Cardiothyreosis in Sub-Saharan Africa (Benin)

作     者：Annelie Kerekou-Hode Philippe Adjagba Samiratou Mama Bio Aude Gaou 

作者机构：University Clinic of Endocrinology National University Hospital Center Hubert Koutoukou Manga Cotonou Benin University Cardiology Clinic National University Hospital Center Hubert Koutoukou Manga Cotonou Benin 

出 版 物：《Open Journal of Endocrine and Metabolic Diseases》 (内分泌与新陈代谢疾病期刊（英文）)

年 卷 期：2019年第9卷第11期

页      面：119-126页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Hyperthyroidism Cardiothyreosis Africa 

摘      要：This is a retrospective study over a 5-year period from January 1, 2013 to December 31, 2018. The diagnosis of cardiothyreosis was retained before clinical signs of hyperthyroidism confirmed to biology by an elevation of T4 and a collapse of ultrasensitive TSH associated with at least one of the following heart failure: insufficiency heart disease, coronary heart failure, rhythm disorder. Sociodemographic, anthropometric, clinical and paraclinical data were analyzed from medical records. Follow-up was evaluated over a period of 6 months to one year after being put on synthetic antithyroids. Results: Of 72 patients seen with hyperthyroidism conditions during the period, we identified 10 cases of cardiothyresis at the departments of Endocrinology and Cardiology of the CNHU/HKM Teaching hospital of Cotonou, Benin. The frequency of cardiothyreosis among hyperthyroidsis was 13.88%. The mean-age for our patients was 50.9 years with bounds from 29 to 79 years. The predominance was female, 8 women for 2 men. A clinical background of high blood pressure is founded in 6/10 patients;4/10 had a history of hyperthyroidism. All patients had heart failure associated with complete arrhythmia by atrial fibrillation in 6 patients. The multi-modular goiter was found in 5/10 of the patients, the vascular goiter 5/10. Synthetic antithyroids, hygienic-dietary measures and a specific treatment for heart failure were used. The average length of hospital’s stay was 7 days. Immediate development is satisfactory with euthyroidism in all patients and improved functional signs. Conclusion: Cardiothyreosis is infrequent in Cotonou. This is a serious complication of hyperthyroidism, which is expensive to manage. Hence the need for early diagnosis and effective treatment of hyperthyroidism.