Genome-wide evolution of MAPKs family and their expression in response to bacterial infection in seahorse Hippocampus erectus

作     者：Kai WANG Xin WANG Qiang ZOU Han JIANG Rongrong ZHANG Yanan TIAN Lele ZHANG Qiang LIN Kai WANG;Xin WANG;Qiang ZOU;Han JIANG;Rongrong ZHANG;Yanan TIAN;Lele ZHANG;Qiang LIN

作者机构：School of AgricultureLudong UniversityYantai 264025China CAS Key Laboratory of Tropical Marine Bio-resources and EcologySouth China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)Guangzhou 511458China Yantai Branch of Shandong Technology Transfer CenterChinese Academy of SciencesYantai 264003China University of Chinese Academy of SciencesBeijing 100049China 

出 版 物：《Journal of Oceanology and Limnology》 (海洋湖沼学报（英文）)

年 卷 期：2021年第39卷第6期

页      面：2309-2321页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 0905[农学-畜牧学] 09[农学] 071007[理学-遗传学] 090501[农学-动物遗传育种与繁殖] 

基　　金：Supported by the Shandong Province Science and Technology Support Program for Outstanding Youth of Colleges and Universities(No.2020KJF007) the Shandong Province Science and Technology Research Program for Colleges and Universities(No.J18KA146) the Yantai Foundation for Development of Science and Technology(Nos.2020LJRC120,2019CXJJ040) the Weihai Foundation for Development of Science and Technology(No.2017GNS10) the Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(No.GML2019ZD0407) the Guangdong Basic and Applied Basic Research Foundation(No.2019A1515110199) 

主　　题：mitogen-activated protein kinases(MAPKs) Hippocampus erectus genomic structure positive selection immune regulation 

摘      要：Seahorses have evolved many unique biological traits,including a male brood pouch,the absence of caudal and pelvic fins,and the lack of spleen and gut-associated lymphatic *** mitogenactivated protein kinases(MAPKs)are known to be involved in various important biological processes including growth,differentiation,immunity,and stress ***,we hypothesized that the adaptive evolution and expression of the MAPK gene family in seahorse may differ from those of other teleost *** identified positive selection sites in the erk2,erk5,jnk1,and p38αMAPK genes of the lined seahorse Hippocampus erectus and tiger-tailed seahorse Hippocampus comes.A novel expression profile of MAPK cascade genes was found in seahorse larvae during the first day after birth based on the RNA-seq data of ***,which refl ected vital signs of immune response to its parental immune *** expression patterns of the four positively selected MAPK genes were analyzed following the bacterial challenge of Vibrio fortis,revealing their upregulation pattern in brood pouch and other immune *** study enriched our knowledge of the evolution of the *** MAPK subfamilies,and could help better understanding the functional role of MAPKs in teleosts.