Comparison of outcomes for percutaneous coronary intervention in men and women with unprotected left main disease

作     者：Sheng-Wen LIU Chang-Dong GUAN Feng-Huan HU Jue CHEN Ke-Fei DOU Wei-Xian YANG Yong-Jian WU Yue-Jin YANG Bo XU Shu-Bin QIAO Sheng-Wen LIU;Chang-Dong GUAN;Feng-Huan HU;Jue CHEN;Ke-Fei DOU;Wei-Xian YANG;Yong-Jian WU;Yue-Jin YANG;Bo XU;Shu-Bin QIAO

作者机构：Department of CardiologyFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical SciencesBeijingChina Catheterization LaboratoriesFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical SciencesBeijingChina 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2021年第18卷第3期

页      面：168-174页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：coronary outcome patients 

摘      要：BACKGROUND Percutaneous coronary intervention(PCI)in patients with unprotected left main coronary artery disease(ULMCAD)is increasing strategy in coronary artery ***,there is a lack of knowledge on the impact of sex on outcomes of patients undergoing ULMCAD *** From January 2004 to December 2015,there were 3,960 patients undergoing ULMCAD PCI at our institution,including 3,121(78.8%)men and 839(21.2%)*** clinical outcome included the incidence of major adverse cardiac events(MACE)(the composite of all-cause death,myocardial infarction(MI),and revascularization),all-cause death,MI,revascularization at three years *** Compared with men,women had not significantly different MACE(14.7%vs.14.6%,P=0.89),all-cause death(3.5%vs.3.7%,P=0.76),MI(5.0%vs.4.3%,P=0.38),revascularization(9.1%vs.8.9%,P=0.86),*** adjustment,rates of MACE(HR=1.49;95%CI:1.24−1.81;P0.0001)and all-cause death(HR=1.65;95%CI:1.09−2.48;P=0.017)occurred more frequently in male patients,as well as revascularization(HR=1.46;95%CI:1.16−1.85;P=0.001).CONCLUSION In this analysis,compared to men,women undergoing ULMCAD PCI have better outcomes of MACE,allcause death,and revascularization.