Impact of leg bending in the patient-specific computational fluid dynamics of popliteal stenting
作者机构：Department of Civil Engineering and ArchitectureUniversity of PaviaPaviaItaly Department of Surgical and Integrated Diagnostic SciencesUniversity of GenoaGenoaItaly Department of RadiologyIRCCS Ospedale Policlinico San MartinoGenoaItaly Vascular and Endovascular Surgery UnitIRCCS Ospedale Policlinico San MartinoGenoaItaly
出 版 物：《Acta Mechanica Sinica》 (力学学报（英文版）)
年 卷 期：2021年第37卷第2期
页 面：279-291页
核心收录：
学科分类：080704[工学-流体机械及工程] 080103[工学-流体力学] 08[工学] 0807[工学-动力工程及工程热物理] 0801[工学-力学（可授工学、理学学位）]
主 题：Popliteal artery aneurysm Peripheral stenting Endovascular treatment Femoropopliteal segment Medical image analysis
摘 要：Endovascular treatment of the femoro-popliteal artery has recently become a valuable therapeutic option for popliteal arterial ***,its efficacy remains controversial due to the relatively high rate of complications,such as stent occlusion as result of intra-stent *** elucidation of the interplay among vessel geometrical features,local hemodynamics,and leg bending seems crucial to understand onset and progression of popliteal intra-stent *** this aim,patient-specific computational fluid dynamic simulations were performed in order to assess the intra-stent hemodynamics of two patients endovascularly treated for popliteal arterial aneurysm by stent-grafts and experiencing intra-stent *** Newtonian and non-Newtonian blood rheological models were *** were presented in terms of tortuosity,luminal area exposed to low(1.5 Pa)time-averaged wall shear stress(TAWSS),area exposed to high(0.3)oscillatory shear index(OSI),and flow *** outcomes demonstrated that leg bending induced significant hemodynamic differences(50%increase)in both patients for all the considered variables,except for OSI in one of the two considered *** both leg configurations,stent-graft overlapping induced a severe discontinuity of the lumen diameter where the proximal stented zone is characterized by low tortuosity,low velocity,low helicity,low TAWSS,and high OSI;while the distal part has higher tortuosity,velocity,helicity,TAWSS,and lower *** study on applied boundary conditions showed that the different inlet velocity profiles for a given inlet waveform affect slightly the numerical solution;conversely,the shape and magnitude of the prescribed inlet waveform is *** on the comparison between the Newtonian and non-Newtonian blood models,the area with low TAWSS is greater in the Newtonian model for both patients,while no significant difference occurs between the surfaces with hig
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