The neurosphere assay:an effective in vitro technique to study neural stem cells
The neurosphere assay: an effective in vitro technique to study neural stem cells作者机构:Instituto de Medicina Molecular João Lobo AntunesFaculdade de MedicinaUniversidade de LisboaLisboaPortugal Instituto de Farmacologia e NeurociênciasFaculdade de MedicinaUniversidade de LisboaLisboaPortugal Instituto de Biologia MolecularFaculdade de MedicinaUniversidade de LisboaLisboaPortugal
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2021年第16卷第11期
页 面:2229-2231页
核心收录:
学科分类:0710[理学-生物学] 07[理学] 071006[理学-神经生物学]
基 金:supported by IF/01227/2015 and UID/BIM/50005/2019,projeto financiado pela Fundação para a Ciência e a Tecnologia(FCT)/Ministério da Ciência,Tecnologia e Ensino Superior(MCTES)através de Fundos do Orçamento de Estado.RS(SFRH/BD/128280/2017),FFR(IMM/CT/35-2018),DML(PD/BD/141784/2018) RSR(SFRH/BD/129710/2017)received a fellowship from FCT
摘 要:Neural stem cells(NSCs)are known to be present in the adult mammalian brain where they constitutively differentiate into the neuronal,astroglial,and oligodendroglial lineages,in defined processes termed neurogenesis,ast rogl iogenesis and oligodendrogenesis,respectively(reviewed in Braun and Jessberger,2014).During brain development,NSCs are present throughout the brain,becoming progressively restricted to defined brain *** the adult brain,NSCs are mainly present in areas classically known as neurogenic niches,*** subventricular zone(SVZ),along the lateral walls of the lateral ventricles,and the subgranular zone,located in the dentate gyrus(DG)of the hippocampus.