Effects of Overwintering on the Survival and Vector Competence of Aedes albopictus in the Urban Life Cycle of Dengue Virus in Guangzhou,China

作     者：Yue Chen Ronghua Chen Jianrong Gao Chunyuan Li Jun Liu Zhijian Zhou Ruiwen Ren Yue Chen;Ronghua Chen;Jianrong Gao;Chunyuan Li;Jun Liu;Zhijian Zhou;Ruiwen Ren

作者机构：Center for Disease Prevention and Control of the Southern Theatre Command of the PLAGuangzhou510507China Guangdong Arbovirus Diseases Emergency Technology Research CenterGuangzhou510507China 

出 版 物：《Virologica Sinica》 (中国病毒学（英文版）)

年 卷 期：2021年第36卷第4期

页      面：755-761页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：This project was supported by the Provincial Science and Technology Projects of Guangdong Province,China(Grant numbers:2014A020219007,2015A020218003,2016A020219006 and 2017A020215101) the Medical Scientific Research Foundation of Guangdong Province,China(Grant numbers:A2018167) 

主　　题：Dengue virus(DENV) Aedes albopictus Overwintering Vertical transmission Subtropical region 

摘      要：The Pearl River Delta,where Aedes albopictus(***)is the only vector for dengue transmission,has exhibited one of the highest dengue burdens in southern China in recent ***,whether dengue virus(DENV)can overwinter in *** in the Pearl River Delta has not been determined to *** this study,300 field-derived *** mosquitoes from Guangzhou that were infected with the predominant endemic DENV-1 strain were investigated under simulated urban balcony environment from October 16,2016,to June 16,*** vertical transmission of DENV in the infected overwintering *** was *** DENV infected overwintering mosquitoes were evaluated for viral load at nine-time points using reverse transcription-quantitative *** vector competence of the infected overwintering *** was also investigated by using suckling *** mosquitoes and larvae were found during the observation *** vertical transmission of DENV-1 was *** DENV-1-positive rates between overwintering males and females had no *** proportion of DENV-1-positive overwintering mosquitoes decreased over time and had no difference beyond three months after the *** mosquitoes can spread DENV-1 to *** engorged mosquitoes at an ambient temperature below 15℃were *** ratio of engorged mosquitoes was positively correlated with the ambient temperature ranging from 15 to 30℃.Our results demonstrated that DENV can overwinter in *** in the Pearl River Delta,*** is the competent vector for DENV,and maintain autochthonous dengue outbreaks in the Pearl River Delta through vertical transmission.