Conserved host-pathogen interactions identify novel treatment options in betacoronavirus infections
作者机构:Charity-Universitatsmedizin Berlincorporate member of Freie Umversitat BerlinHumboldt-Universitat zu Berlinand Berlin Institute of HealthBerlinGermany Center for Digital HealthBerlin Institute of Health(BIH)BerlinGermany Health Data Science UnitHeidelberg University Hospital and BioQuantHeidelbergGermany
出 版 物:《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗(英文))
年 卷 期:2021年第6卷第3期
页 面:557-559页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
基 金:Open Access funding enabled and organized by Projekt DEAL
主 题:identif interactions treatment
摘 要:In a recent study published in Science,1 Gordon et *** the host-pathogen interactome of the coronaviruses SARS-CoV-1,SARS-CoV-2,and MERS-CoV,all of which caused lethal outbreaks in the past two *** functionally characterize a number of these interactions,leveraging the information to identify promising candidate molecules for drug-repurposing.