Novel antibacterial cellulose diacetate-based composite 3D scaffold as potential wound dressing

作     者：Wencheng Liang Mingli Jiang Junyong Zhang Xiaoming Dou Yan Zhou Yun Jiang Li Zhao Meidong Lang Wencheng Liang;Mingli Jiang;Junyong Zhang;Xiaoming Dou;Yan Zhou;Yun Jiang;Li Zhao;Meidong Lang

作者机构：Center of Photonics&Bio-Medical DiagnosisSchool of ScienceEast China University of Science and TechnologyShanghai 200237China State Key Laboratory of Bioreactor EngineeringSchool of BiotechnologyEast China University of Science and TechnologyShanghai 200237China Shanghai Key Laboratory of Advanced Polymeric MaterialsKey Laboratory for Ultrafine Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China State Key Laboratory of Bioreactor EngineeringNew World Institute of BiotechnologyEast China University of Science and TechnologyShanghai 200237China The Library of Zhejiang University of TechnologyZhejiang University of TechnologyHangzhou 310023China 

出 版 物：《Journal of Materials Science & Technology》 (材料科学技术（英文版）)

年 卷 期：2021年第89卷第30期

页      面：225-232页

核心收录：

学科分类：0817[工学-化学工程与技术] 0806[工学-冶金工程] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0703[理学-化学] 0802[工学-机械工程] 0801[工学-力学（可授工学、理学学位）] 0702[理学-物理学] 

基　　金：financially supported by the National Key Research and Development Program(No.2016YFC1100703) 

主　　题：Cellulose diacetate Electrospinning 3D scaffold Wound dressing 

摘      要：In this work,novel antibacterial cellulose diacetate/poly(ethylenimine)/hyaluronic acid(CDA/PEI/HA)composite three-dimension(3D)scaffolds were prepared through electrospinning and ***,CDA/PEI 2D composite nanofiber membranes were prepared by electrospinning,and then the CDA/PEI/HA 3D composite scaffolds were fabricated by post-processing and freeze-drying of CDA/PEI *** particular,HA was added to improve the biocompatibility of composite *** with CDA/PEI scaffolds,CDA/PEI/HA composite scaffolds showed higher water absorbing rate,higher water retention rate and higher mechanical ***,CDA/PEI/HA composite scaffolds with abundant positive charge were benefit for improving antibacterial ***/PEI/HA scaffolds with biology function of HA were benefit for improving hemocompatibility and cell proliferation of CDA/PEI *** summary,antibacterial CDA/PEI/HA scaffolds could protect wound from bacterial infection,improve cellular behavior and accelerate wound ***,CDA/PEI/HA scaffolds could be potential application for wound dressing.