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Nanowire-mediated miR NA delivery

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Science China Life Sciences 2024年

作者： Yuan Wang Bing Chen Laboratory for Biomaterials and Drug Delivery Department of Anesthesiology Division of Critical Care Medicine Boston Children's Hospital Harvard Medical School College of Electronic and Optical Engineering and College of Flexible electronics (Future Technology) Nanjing University of Posts and Telecommunications

In the ever-evolving nanomedicine and biotechnology, the pursuit of advanced drug delivery systems that induce precise positioning and targeting in the complex biological landscape for personalized and efficient therapies has become a paramount endeavor (Vargason et al., 2021).Central to this trend is the delivery of functional microRNAs (miRNAs), which play crucial roles in regulating gene expression (Li et al., 2021).

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An LED-Side-Pumped Intracavity Frequency-Doubled Nd,Ce:YAG Laser Producing a 2W Q-Switched Red Beam

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Chinese Physics Letters 2024年第3期41卷 44-47页

作者：沈建平徐少聪芦鹏江容容王巍张四维邢凤阳陈阳陈亮 College of Electronic and Optical Engineering&College of Flexible electronics Nanjing University of Posts and TelecommunicationsNanjing 210046China Laser Institute Qilu University of Technology(Shandong Academy of Sciences)Qingdao 266000China

We report a high-average-power acousto-optic(AO)Q-switched intracavity frequency-doubled red laser based on a high-efficiency light-emitting-diode(LED)pumped two-rod Nd,Ce:YAG laser *** quasi-continuous wave operation... 详细信息

关键词： pumped switched laser

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Depolarization Degree to Determine Dihedral Attribute of Radar Target

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Journal of Electromagnetic Analysis and Applications 2024年第6期16卷 85-101页

作者： Faisal Aldhubaib electronics Department Faculty of Technological Studies Public Authority for Applied Education Shuwaikh Kuwait

This paper investigates the ability of the depolarization degree, derived from the characteristic polarization states at the resonant frequency set, to identify corner or swept, i.e. dihedral, changes in same-class targets by a metallic wire example. A well-estimated depolarization degree requires a robust extraction of the fundamental target resonance set in two orthogonal sets of fully co-polarized and cross-polarized polarization channels, then finding the null polarization states using the Lagrangian method. Such depolarization degree per resonance mode has the potential to form a robust feature set because it is relatively less sensitive to onset ambiguity, invariant to rotation, and could create a compact, recognizable, and separable distribution in the proposed feature space. The study was limited to two targets with two swept changes of fifteen degrees within normal incidence;under a supervised learning approach, the results showed that the identification rate converging to upper-bound (100%) for a signal-to-noise ratio above 20 dB and lower-bound around (50%) below −10 dB.

关键词： Polarimetry Radar Target Recognition Time-Domain Analysis Remote Sensing

“Steric Armor”Strategy of Blue Fluorescent Emitters against Photooxidation-Induced Degradation

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Chinese Journal of Chemistry 2024年第11期42卷 1223-1229页

作者： Sha-Sha Wang Jing-Rui Zhang Kuan-De Wang Hao-Ran Li Peng-Hui Meng Yang Zhou Xiang Yu Ying Wei Quan-You Feng Yu-He Kan Ling-Hai Xie Centre for Molecular Systems and Organic Devices(CMSOD) State Key Laboratory of Organic Electronics and Information Displays&Institute of Advanced MaterialsJiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)Nanjing University of Posts&TelecommunicationsNanjingJiangsu210023 China Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials School of Chemistry and Chemical EngineeringHuaiyin Normal UniversityHuai'anJiangsu223300 China

Stability against oxygen is an important factor affecting the performance of organic semiconductor *** photooxidation stability can prolong the service life of the device and maintain the mechanical and photoelectric properties of the ***,various encapsulation methods from molecular structure to macroscopic device level are used to improve photooxidation ***,we adopted a crystallization strategy to allow 14H-spiro[dibenzo[c,h]acridine-7,9′-fluorene](SFDBA)to pack tightly to resist fluorescence decay caused by *** this case,the inert group of SFDBA acts as a“steric armor”,protecting the photosensitive group from being attacked by ***,compared with the fluorescence quenching of SFDBA powder under 2 h of sunlight,SFDBA crystal can maintain its fluorescence emission for more than 8 h under the same ***,the photoluminescence quantum yields(PLQYs)of the crystalline film is 327%higher than that of the amorphous *** shows that the crystallization strategy is an effective method to resist oxidation.

关键词： Organic semiconductor Photooxidation Spirocyclic aromatic hydrocarbons Crystal engineering Fluorescence

高灵敏度和高线性度的可拉伸应变传感器的分层结构设计

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Science China Materials 2024年第7期67卷 2319-2328页

作者：武春锦彭义豪王少龙邱炳人李冠军曹玉杰赖文勇 State Key Laboratory of Organic electronics and Information Displays Institute of Advanced Materials(IAM)School of Chemistry and Life SciencesNanjing University of Posts&TelecommunicationsNanjing 210023China School of Environmental Science Nanjing Xiaozhuang UniversityNanjing 211171China

对柔性电子设备日益增长的需求使得开发具有高灵敏度和高线性度的传感器更加迫切.由于拉伸应变下不可逆结构损伤诱导电阻线性急剧增加,现有的可拉伸应变传感器难以完美地同时实现这两个特性.针对这一问题,本文提出了一种兼具表面褶皱和... 详细信息

对柔性电子设备日益增长的需求使得开发具有高灵敏度和高线性度的传感器更加迫切.由于拉伸应变下不可逆结构损伤诱导电阻线性急剧增加,现有的可拉伸应变传感器难以完美地同时实现这两个特性.针对这一问题,本文提出了一种兼具表面褶皱和体相梯度孔隙的新型分级互连结构,利用水热活化机制精确控制纳米级褶皱间距,通过调控相分离中热力学和动力学行为构筑出体相梯度多孔结构,通过改变器件两侧曲率实现各向异性特征,深入研究各种设计的功效、量化几何结构对灵敏度的有效贡献和追踪形态演变.基于器件显著的灵敏度和各向异性,所制备的传感器能够有效监测静态和动态位移、表面运动、二维应变信号变化以及预测液位随时间变化.本工作为实现高质量的感知能力提供了一种广泛适用、适应性强、可扩展且具有成本效益的方法.

关键词： stretchable electronics stretchable strain sensors surface wrinkles sensitivity linearity

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Application of Stork Optimization Algorithm for Solving Sustainable Lot Size Optimization

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Computers, Materials & Continua 2024年第8期80卷 2005-2030页

作者： Tareq Hamadneh Khalid Kaabneh Omar Alssayed Gulnara Bektemyssova Galymzhan Shaikemelev Dauren Umutkulov Zoubida Benmamoun Zeinab Monrazeri Mohammad Dehghani Department of Mathematics Al Zaytoonah University of JordanAmman11733Jordan faculty of Information Technology Al-Ahliyya Amman UniversityAmman19328Jordan Department of Mathematics Faculty of ScienceThe Hashemite UniversityP.O.Box 330127Zarqa13133Jordan Department of Computer Engineering International Information Technology UniversityAlmaty050000Kazakhstan faculty of Engineering Liwa CollegeAbu Dhabi41009United Arab Emirates Department of Electrical and electronics Engineering Shiraz University of TechnologyShiraz***Iran

The efficiency of businesses is often hindered by the challenges encountered in traditional Supply Chain Manage-ment(SCM),which is characterized by elevated risks due to inadequate accountability and *** address these challenges and improve operations in green manufacturing,optimization algorithms play a crucial role in supporting decision-making *** this study,we propose a solution to the green lot size optimization issue by leveraging bio-inspired algorithms,notably the Stork Optimization Algorithm(SOA).The SOA draws inspiration from the hunting and winter migration strategies employed by storks in *** theoretical framework of SOA is elaborated and mathematically modeled through two distinct phases:exploration,based on migration simulation,and exploitation,based on hunting strategy *** tackle the green lot size optimization issue,our methodology involved gathering real-world data,which was then transformed into a simplified function with multiple constraints aimed at optimizing total costs and minimizing CO_(2) *** function served as input for the SOA ***,the SOA model was applied to identify the optimal lot size that strikes a balance between cost-effectiveness and *** extensive experimentation,we compared the performance of SOA with twelve established metaheuristic algorithms,consistently demonstrating that SOA outperformed the *** study’s contribution lies in providing an effective solution to the sustainable lot-size optimization dilemma,thereby reducing environmental impact and enhancing supply chain *** simulation findings underscore that SOA consistently achieves superior outcomes compared to existing optimization methodologies,making it a promising approach for green manufacturing and sustainable supply chain management.

关键词： Optimization supply chain management sustainable lot size optimization bio-inspired metaheuristic stork

An Enhanced Clustering-Based(k, t)-Anonymity Algorithm for Graphs

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Chinese Journal of electronics 2024年

作者： Yuanyuan WANG Xing ZHANG Zhiguang CHU Wei SHI Xiang LI School of electronics and Information Engineering Liaoning University of Technology Key Laboratory of Security for Network and Data in Industrial Internet of Liaoning Province faculty of Information Technology Beijing University of Technology

As people become increasingly reliant on the Internet, securely storing and publishing private data has become an important issue. In real life, the release of graph data can lead to privacy breaches, which is a highly challenging problem. Although current research has addressed the issue of identity disclosure, there are still two challenges: First, the privacy protection for large-scale datasets is not yet comprehensive; Second, it is difficult to simultaneously protect the privacy of nodes, edges, and attributes in social networks. To address these issues, this paper proposes a(k, t)-graph anonymity algorithm based on enhanced clustering. The algorithm uses k-means++ clustering for k-anonymity and t-closeness to improve k-anonymity. We evaluated the privacy and efficiency of this method on two datasets and achieved good results. This research is of great significance for addressing the problem of privacy breaches that may arise from the publication of graph data.

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Dual-Mode Resonant Sectorial Monopole Antenna with Stable Backfire Gain

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Chinese Journal of electronics 2024年

作者： Feiyan JI Heng ZHANG Xiuqiong XING Wenjun LU Lei ZHU Jiangsu Key Laboratory of Wireless Communications Nanjing University of Posts and Telecommunications Key Laboratory of Wireless Sensor Network & Communication Shanghai Institute of Microsystem and Information TechnologyChinese Academy of Sciences Department of Electrical and Computer Engineering Faculty of Science and Technology University of Macau

A novel design approach to wideband, dual-mode resonant monopole antenna with stable, enhanced backfire gain is advanced. The sectorial monopole evolves from a linear, 0.75-wavelength electric prototype monopole under wideband dual-mode resonant operation. As theoretically predicted by the two resonant modes TE9/5,1and experimentally validated at 2.4-GHz band, the designed antenna exhibits a wide impedance bandwidth over 90.1%(i.e., 2.06-5.44 GHz), in which the stable gain bandwidth in the backfire,-x-direction(θ = 90°, φ = 180°) with peak value of 3.2 dBi and fluctuation less than 3 dB is up to 45.3%(i.e., 3.74-5.44 GHz). It is concluded that the stable wideband backfire gain frequency response should be owing to the high-order resonant mode in the unique sectorial monopole antennas.

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Optimization of Cooperative RelayingMolecular Communications for Nanomedical Applications

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1259-1275页

作者： Eman S.Attia Ashraf A.M.Khalaf Fathi E.Abd El-Samie Saied M.Abd El-atty Konstantinos A.Lizos Osama Alfarraj Heba M.El-Hoseny Department of Electrical Engineering Faculty of EngineeringMinia UniversityMinia61111Egypt Department of electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Department of Informatics Faculty of Mathematics and Natural SciencesUniversity of Oslo(UiO)OsloNorway Computer Science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Department of Computer science The Higher Future Institute for Specialized Technological StudiesEl ShoroukEgypt

Recently,nano-systems based on molecular communications via diffusion(MCvD)have been implemented in a variety of nanomedical applications,most notably in targeted drug delivery system(TDDS)***,because the MCvD is unreliable and there exists molecular noise and inter symbol interference(ISI),cooperative nano-relays can acquire the reliability for drug delivery to targeted diseased cells,especially if the separation distance between the nano transmitter and nano receiver is *** this work,we propose an approach for optimizing the performance of the nano system using cooperative molecular communications with a nano relay scheme,while accounting for blood flow effects in terms of drift *** fractions of the molecular drug that should be allocated to the nano transmitter and nano relay positioning are computed using a collaborative optimization problem solved by theModified Central Force Optimization(MCFO)*** the previous work,the probability of bit error is expressed in a closed-form *** is used as an objective function to determine the optimal velocity of the drug molecules and the detection threshold at the nano *** simulation results show that the probability of bit error can be dramatically reduced by optimizing the drift velocity,detection threshold,location of the nano-relay in the proposed nano system,and molecular drug budget.

关键词： Nanomedical system molecular communication cooperative relay optimization