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Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance neural regeneration after traumatic brain injury

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Neural Regeneration Research 2023年第9期18卷 1990-1998页

作者： Xiao-Yin Liu Yin-He Feng Qing-Bo Feng Jian-Yong Zhang Lin Zhong Peng Liu Shan Wang Yan-Ruo Huang Xu-Yi Chen Liang-Xue Zhou Department of Neurosurgery West China HospitalWest China Medical SchoolSichuan UniversityChengduSichuan ProvinceChina Tianjin Key Laboratory of Neurotrauma Repair Pingjin Hospital Brain CenterCharacteristic Medical Center of Chinese People’s Armed Police ForceTianjinChina Department of Respiratory and Critical Care Medicine People’s Hospital of Deyang CityAffiliated Hospital of Chengdu College of MedicineDeyangSichuan ProvinceChina Department of Liver Surgery&Liver Transplantation State Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengduProvinceChina Department of General Surgery the Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou ProvinceChina The First Affiliated Hospital of Chengdu Medical College ChengduSichuan ProvinceChina Department of Anesthesiology Huashan HospitalFudan UniversityShanghaiChina Institute of Medical security for maritime Rights Protection of Characteristic Medical center of Chinese People’s Armed Police Force TianjinChina

There are various clinical treatments for traumatic brain injury,including surgery,drug therapy,and rehabilitation therapy;howeve r,the therapeutic effects are *** combined with exosomes represent a promising but challenging method for improving the repair of traumatic brain *** this study,we determined the ability of a novel 3D-printed collagen/chitosan scaffold loaded with exosomes derived from neural stem cells pretreated with insulin-like growth factor-1(3D-CC-INEXOS) to improve traumatic brain injury repair and functional recove ry after traumatic brain injury in *** scaffolds comprising collagen,chitosan,and exosomes derived from neural stem cells pretreated with insulin-like growth fa ctor-1(INEXOS) continuously released exosomes for *** of 3D-CC-INExos scaffolds significantly improved motor and cognitive functions in a rat traumatic brain injury model,as assessed by the Morris water maze test and modified neurological seve rity *** addition,immunofluorescence staining and transmission electron microscopy showed that3D-CC-INExos implantation significantly improved the recove ry of damaged nerve tissue in the injured *** conclusion,this study suggests that transplanted3D-CC-INExos scaffolds might provide a potential strategy for the treatment of traumatic brain injury and lay a solid foundation for clinical translation.

关键词： 3D printing angiogenesis chitosan collagen exosomes functional recovery insulin-like growth factor-1 neural regeneration neural stem cells traumatic brain injury

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Preparation of WO_(3) nanorods with high specific surface area using double-walled carbon nanotubes as template

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Rare Metals 2022年第3期41卷 1051-1056页

作者： Yan-Hong Yin Chun-An Ma Zi-Ping Wu Li-Tao Chen You-Qun Chu State Key Laboratory Breeding Base for Green Chemistry Synthesis Technology International Science and Technology Cooperation Base of Energy Materials and ApplicationCollege of Chemical Engineering and Materials ScienceZhejiang University of TechnologyHangzhou 310032China Engineering Research center of High-Efﬁciency Development and Application Technology of Tungsten Resources(Ministry of Education) School of Materials Science and EngineeringJiangxi University of Science and TechnologyGanzhou 341000China

The preparation of WO_(3) nanorods by double-walled carbon nanotube(DWCNT)template was investi-gated in this *** to that the prepared H_(2)WO_(4)can be isolated by the homogenously dispersed DWCNT bun-dles and secondary accumulation can be avoided effec-tively,the growth of H_(2)WO_(4) can be restrained,and H_(2)WO_(4) nanorods with diameter of 10–50 nm can be *** calcination of the prepared DWCNT/H_(2)WO_(4) com-posite in oxygen,WO_(3) nanorods with diameter of 10–100 nm and high specific surface area of 16.4 m^(2)·g^(-1) can be *** is concluded that the DWCNTs play an im-portant role in the effective mediation of the morphology and size of nano-WO_(3).

关键词： Tungsten oxide Nanorods Double-walled carbon nanotubes Template

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Biomimetic Moth-eye Anti-reflective Poly-(methyl methacrylate)Nanostructural Coating

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Journal of Bionic Engineering 2019年第6期16卷 1030-1038页

作者： Hongbo Xu Liuting Gong Shoucai Zhang Renping Ma Lei Pan Jiupeng Zhao Yao Li MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001China Beijing Institute of Space Mechanics and Electricity Beijing 100094China Beijing Vocational College of Labour and Social security Beijing 102200China center for Composite Material Harbin Institute of TechnologyHarbin 150001China

This study reports a simple imprinting method for the fabrication of biomimetic moth-eye antireflective polymethyl methacrylate(PMMA)nanostructures on the surface of the *** antireflection structured silicon was obtained by Reactive Ion Etching(RIE)*** using the antireflection structured silicon substrate as the imprinting stamp,the biomimetic moth-eye polymer structures showed tapered holes,whose depth and periodicity were around 780 nm and 580 nm,*** reflectance of the resulting PMMA structures was reduced from 10% to less than 1% in the wavelength range from 300 nm to 1600 *** simple methodology can be scaled up via self-loading and nanoimprinting,which may have a promising application in optoelectronic devices and solar cells.

关键词： nanoimprinting sub-wavelength structure antireflective biomimetic moth-eye

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Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants

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Virologica Sinica 2022年第6期37卷 938-941页

作者： Xiaorui Xing Lei Wang Zhen Cui Wangjun Fu Tao Zheng Lili Qin Pingju Ge Aidong Qian Nan Wang Shuai Yuan College of Veterinary Medicine Jilin Agricultural UniversityChangchun130118China College of Animal Science and Technology Jilin Provincial Engineering Research Center of Animal ProbioticsKey Lab of Animal ProductionProduct Quality and SecurityJoint Laboratory of Modern Agricultural Technology International CooperationMinistry of EducationJilin Agricultural UniversityChangchun130118China CAS Key Laboratory of Infection and Immunity National Laboratory of MacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing100101China University of Chinese Academy of Sciences Beijing100101China Acrobiosystems Beijing100101China State Key Laboratory of Virology Wuhan Institute of VirologyChinese Academy of SciencesWuhan430071China

Dear Editor,The COVID-19 pandemic, which is caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), has led to millions of lives lost worldwide. The trimeric spike protein(S) decorating the membrane surface of the infectious virion is responsible for the attachment and entry by binding to the receptor angiotensin-converting enzyme 2(ACE2) in the early replication cycle(Zhou P. et al., 2020). Two subunits S1 and S2 are included in the trimeric glycoprotein.

关键词： ACE2 al. acute

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In-situ growth of CoNi bimetal anchored on carbon nanoparticle/nanotube hybrid for boosting rechargeable Zn-air battery

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Journal of Energy Chemistry 2022年第3期31卷 348-355,I0010页

作者： Jun Li Yongxia Wang Zhengyu Yin Rui He Yihao Wang Jinli Qiao State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Environmental Science and EngineeringDonghua UniversityShanghai 201620China Shanghai Institute of Pollution Control and Ecological security Shanghai 200092China

Exploring highly efficient non-precious metal based catalysts for bifunctional oxygen electrode is crucial for rechargeable metal-air *** this study,with MOFs as precursors,a facile coprecipitation method is designed to realize in-situ growth of the CoNi anchored carbon nanoparticle/nanotube(CoNi/N-CNN)hybrid,which can achieve the simultaneous maximum exposure of both oxygen evolution reaction(OER)and oxygen reduction reaction(ORR)active *** from the unique structure,the CoNi/N-CNN catalyst exhibits excellent electrocatalytic performance for ORR(E_(onset)=1.183 V,E_(1/2)=0.819 V)and a low operating voltage of 1.718 V at 10 mA cm^(−2)(Ej=10)for ***,the home-made rechargeable Zn-air battery with CoNi/N-CNN delivers a high discharge power density up to 209 mW cm^(−2),and an outstanding charge–discharge cycling *** boosted bifunctional electrocatalytic activity can be ascribed to the strong coupling effect between Co/Ni center sites and defect-rich N-anchored carbon featured with porous and nanotube structure,which can introduce uniformly dispersed active sites,tailored electronic configuration,superb conductivity and convenient charge transfer *** hybrid non-precious bimetal based electrocatalyst provides the possibility to develop the low-cost and high-efficient ORR/OER bifunctional electrocatalysts in rechargeable metal-air battery.

关键词： Co Ni/N-CNN Bifunctional electrocatalyst Oxygen electrode Rechargeable Zn-air battery

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An Improved iBAT-COOP Protocol for Cooperative Diversity in FANETs

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Computers, Materials & Continua 2021年第5期67卷 2527-2546页

作者： Shahzad Hameed Qurratul-Ain Minhas Sheeraz Ahmed Shabana Habib Mohammad Kamrul Hasan Muhammad Islam Sheroz Khan Quaid-i-Azam University IslamabadPakistan Iqra National University PeshawarPakistan Network and Communication Technology Lab Center for Cyber SecurityUKMBangiMalaysia Department of Information Technology College of ComputerQassim UniversityBuraydahSaudi Arabia Department of Electrical Engineering Onaizah College of Engineering&Information TechnologyAl-QassimSaudi Arabia

Flying ad hoc networks(FANETs)present a challenging environment due to the dynamic and highly mobile nature of the *** network topology and uncertain node mobility structure of FANETs do not aim to consider only one path *** different techniques are adopted to address the issues arising in FANETs,from game theory to clustering to channel estimation and other statistical *** approaches mostly employ traditional concepts for problem *** of the novel approaches that provide simpler solutions to more complex problems is to use biologically inspired *** Nature-inspired schemes address cooperation and alliance which can be used to ensure connectivity among network *** such species that resembles the dynamicity of FANETs are *** this paper,the biologically inspired metaheuristic technique of the BAT Algorithm is proposed to present a routing protocol called iBATCOOP(Improved BAT Algorithm using cooperation technique).We opt for the design implementation of the natural posture of bats to handle the necessary flying ***,we envision the concept of cooperative diversity using multiple relays and present an iBAT-COOP routing protocol for *** paper employs cooperation for an optimal route selection and reflects on distance,Signal to Noise Ratio(SNR),and link conditions to an efficient level to deal with FANET’s *** way of simulations,the performance of iBAT-COOP protocol outperforms BAT-FANET protocol and reduces packet loss ratio,end-to-end delay,and transmission loss by 81%,21%,and 82%***,the average link duration is improved by 25%compared to the BAT-FANET protocol.

关键词： Routing protocols UAVs FANETs iBATCOOP BATCOOP

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中日韩合作的发展、困境与前景

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China International Studies 2024年第2期 41-68页

作者：巴殿君左天全 center for Northeast Asian Studies Jilin University Institute for Northeast Asian Studies Jilin University

China,Japan,and the Republic of Korea(ROK)are geographically adjacent countries with a major influence in East *** China-Japan-ROK trilateral cooperation mechanism,since its inception in 1999,has made important contributions to the development of the three countries,the prosperity of the broader region,and the world ***,global economic growth is faltering,the political landscape is beset with polarization,security issues are emerging in different regions on a more frequent basis,and the global industrial chain is undergoing a reconstruction.

关键词： landscape peace cooperation

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The Prospect of Situation on the Korean Peninsula and China’s Role

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China International Studies 2020年第2期65卷 51-68页

作者： Zhang Chi the center for Political and Social security Studies Shanghai Institute for Global Security and Governance

The situation on the Korean Peninsula has witnessed a major shift since 2018:the road towards a resolution of the Korean Peninsula nuclear issue has returned to the path of negotiation,and major breakthroughs and improvements have been made in bilateral relations between the US and the DPRK,between North and South Korea,as well as between China and North ***,with major disputes in core issues remaining including the pathway toward nuclear dismantlement and the removal of international sanctions,negotiations between the US and the DPRK have *** the end of 2019,the fifth plenary session of the seventh Central Committee of the Workers’Party of Korea(WPK)made a great strategic adjustment,shifting from the approach of devoting itself to domestic economic development and facilitating negotiations with a peaceful posture,to one of stressing both the economy and the military domestically and exerting more pressure to push negotiations diplomatically.

关键词： breakthrough shifting Korea

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Characteristics of the pollutant emissions in a tunnel of Shanghai on a weekday

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Journal of Environmental Sciences 2018年第9期30卷 136-149页

作者： Rui Li Ya Meng Hongbo Fu Liwu Zhang Xingnan Ye Jianmin Chen Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention Department of Environmental Science&EngineeringInstitute of Atmospheric SciencesFudan UniversityShanghai200433P.R.China Shanghai Institute of Pollution Control and Ecological security Shanghai 200092P.R.China Collaborative Innovation center of Atmospheric Environment and Equipment Technology(CICAEET) Nanjing University of Information Science and TechnologyNanjing 210044China

Tunnel displays a typical semi-closed environment, and multitudes of the pollutants tend to accumulate. The samples of gaseous pollutants and particulate matter （PM） were collected from the Xiangyin tunnel at Shanghai to investigate the characteristics of the pollutant emissions. The results indicated that both gaseous pollutants and PM exhibited much higher concentrations during the rush hours in the morning and at night due to vehicle emission. Two peaks of the PM concentration were observed in the scope of 0.7-1.1 and 3.3-4.7 μm, accounting for 14.6% and 20.3% of the total concentrations, respectively. Organic matter （OM）, EC, and many water-soluble ions were markedly higher at the rush hours in the morning than those at night, implicating comprehensive effects of vehicle types and traffic volume. The particle number concentrations exhibited two peaks at Aitken mode （25 nm and 100 rim） and accumulation mode （600 nm）, while the particle volume concentration displayed high values at the accumulation mode （100-500 nm） and coarse mode （2.5-4.0 μm）. The peak around 100 nm was detected in the morning rush hours, but it diminished with the decrease of the traffic volume. Individual-particle analysis revealed that main particles in the tunnel were Fe-rich particles, K-rich particles, mineral particles, Ca-S rich particles and A1-Si particles. The particles collected at the rush hours displayed marked different morphologies, element concentrations and particle sizes compared to the ones collected at the non-rush period. The data presented herein could shed a light on the feature of vehicle emissions.

关键词： Tunnel Vehicle emission Size distribution Morphology

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FedIERF: Federated Incremental Extremely Random Forest for Wearable Health Monitoring

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Journal of Computer Science & Technology 2023年第5期38卷 970-984页

作者：胡春雨忽丽莎袁林陆佃杰吕蕾陈益强 Key Laboratory of Computing Power Network and Information security Ministry of EducationShandong Computer Science Center(National Supercomputer Center in Jinan)Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353China Shandong Provincial Key Laboratory of Computer Networks Shandong Fundamental Research Center for Computer ScienceJinan 250000China Shandong Provincial Key Laboratory for Novel Distributed Computer Software Technology Jinan 25000China Institute of Information Technology Hebei University of Economics and BusinessShijiazhuang 050061China School of Information Science and Engineering Shandong Normal UniversityJinan 250358China Institute of Computing Technology Chinese Academy of SciencesBeijing 100190China

Wearable health monitoring is a crucial technical tool that offers early warning for chronic diseases due to its superior portability and low power ***,most wearable health data is distributed across dfferent organizations,such as hospitals,research institutes,and companies,and can only be accessed by the owners of the data in compliance with data privacy *** first challenge addressed in this paper is communicating in a privacy-preserving manner among different *** second technical challenge is handling the dynamic expansion of the federation without model *** address the first challenge,we propose a horizontal federated learning method called Federated Extremely Random Forest(FedERF).Its contribution-based splitting score computing mechanism significantly mitigates the impact of privacy protection constraints on model *** on FedERF,we present a federated incremental learning method called Federated Incremental Extremely Random Forest(FedIERF)to address the second technical *** introduces a hardness-driven weighting mechanism and an importance-based updating scheme to update the existing federated model *** experiments show that FedERF achieves comparable performance with non-federated methods,and FedIERF effectively addresses the dynamic expansion of the *** opens up opportunities for cooperation between different organizations in wearable health monitoring.

关键词： federated learning incremental learning random forest wearable health monitoring

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