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Asymptomatic Screening of Clients on Opioid Substitution Therapy for Tuberculosis: An Experience from India

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Journal of Tuberculosis Research 2019年第3期7卷 131-134页

作者： Banuru Muralidhara Prasad Mandeep Singh Mukesh Gupta Thekkur K. Pruthu Rajeev Kumar Parmesh C. Bhatnagar Sarabjit Singh Chadha The International Union against Tuberculosis and Lung Disease (The Union) New Delhi India Medical Officer at ost Centre Government of Punjab Jalandhar Punjab India Radiologist at Private Health Facility Jalandhar Punjab India Voluntary Health Association of India (VHAI) New Delhi India Foundation for Innovate New Diagnosis (FIND) New Delhi India

Clients on Opioid Substitution Therapy (ost) may be at risk of TB. We screened for tuberculosis in asymptomatic ost clients using Chest-X-ray (CXR) and sputum from those with CXR suggestive of TB were tested using Xpert MTB/Rif. Among 472 who underwent CXR, 0.1% had CXR suggestive of TB. The number needed to screen was 118 clients for one CXR suggestive of TB. All four clients with CXR suggestive of TB underwent MTB/Rif assay and one was diagnosed with TB. The TB patient was asymptomatic and could have been missed through the passive approach. We recommend further studies to explore ACF among ost clients.

关键词： ost Tuberculosis Active case Finding Screening Chest X-Ray

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老年人的蛋白质摄入量和骨病

营养健康新观察 2009年第1期 20-25页

作者： René Rizzoli Patrick Ammann Thierry Chevalley Jean-Philippe Bonjour 王劲 Bony diseases division centre collaborateur de I'OMS pour I'ostéoporose et les maladies osseusesdépartement de médecine internehpital cantonal universitaire

营养不良、大多数显著的蛋白质缺乏,不仅通过减少骨量,而且通过改变肌肉功能来导致骨质疏松性骨折的发生。此外,营养不良与骨质疏松性骨折发病率增加有关。生长调节素系统(IGF-1)可能直接涉及老年人髋部骨质疏松性骨折及其并发症的发病... 详细信息

营养不良、大多数显著的蛋白质缺乏,不仅通过减少骨量,而且通过改变肌肉功能来导致骨质疏松性骨折的发生。此外,营养不良与骨质疏松性骨折发病率增加有关。生长调节素系统(IGF-1)可能直接涉及老年人髋部骨质疏松性骨折及其并发症的发病机制。低IGF-1水平是髋骨骨折的危险因素。维生素D和钙摄入量合适的研究对象,给予纠正自然蛋白质摄入量不足的蛋白质补充量可增加循环血中IGF-1,改善髋骨骨折后的临床结局,和预防股骨近端骨矿物质密度的丢失。补充蛋白质也可明显减少住院患者康复治疗的时间。这些资料强调了适量营养素摄入量在骨质疏松性骨折防治方面的重要性。

关键词：骨折 IGF-1 营养骨质疏松症

Bridging the Divide Between Iterative Optical Polishing and Automation

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Nanomanufacturing and Metrology 2023年第3期6卷 69-90页

作者： David Walker Juan I.Ahuir‑Torres Yasemin Akar Paul A.Bingham Xun Chen Michal Darowski Oliver Fähnle Philippe Gambron Frankie F.Jackson Hongyu Li Luke Mason Rakesh Mishra Abdullah Shahjalal Guoyu Yu University of Huddersfeld Laboratory for Ultra Precision Surfaces SciTech DaresburyTechSpace OneDaresbury WA44ABUK General Engineering Research Institute Liverpool John Moores UniversityLiverpool L33AFUK Department of Engineering and Technology University of HuddersfeldWest Yorkshire HD13DHUK Materials and Engineering Research Institute Shefeld Hallam UniversityShefeld S11WBUK Departement Technik OST-Eastern Switzerland University of Applied SciencesWerdenbergstrasse 49471 BuchsSwitzerland Research Center for Space Optical Engineering Harbin Institute of TechnologyHarbin 150001China STFC Hartree Centre Rutherford Appleton LaboratoryDidcot OX110DEUK Daresbury Laboratory STFC Hartree CentreDaresbury WA44ADUK Department of ICT University of AgderGrimstadNorway Zeeko Ltd CoalvilleLeicestershire LL673FWUK

Several recent business reports have described the global growth in demand for optical and photonic components,paralleled by technical reports on the growing shortage of skilled manufacturing staff to meet this *** is remarkable that producing ultraprecision surfaces remains so dependent on people,in contrast to other sectors of the economy,e.g.,car ***,training can play some role,but ultimately,only process automation can provide the *** paper explores why automation is a challenge and summarizes multidisciplinary work aiming to assemble the building blocks required to realize automation.

关键词： Optics Photonics Polishing Glass Ultraprecision Abrasives Asphere Free-form Deterministic

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老年人的蛋白质摄入量和骨病

老年人的蛋白质摄入量和骨病

ABA Signaling in Guard Cells Entails a Dynamic Protein-Protein Interaction Relay from the PYL-RcaR Family Receptors to Ion Channels

作者： Ren Rizzoli Patrick Ammann Thierry Chevalley Jean-Philippe Bonjour 王劲 Bony diseases division centre collaborateur de I’ OMS pou l’ ost oporose et lesmaladies osseuses d partement dem decine internehopital cantonal universitaireCH 1211 Geneva 14Switzerland

关键词：骨折 IGF-1 营养骨质疏松症

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Molecular Plant 2013年第2期6卷 528-538页

作者： Sung Chul Lee Chae Woo Lim Wenzhi Lan Kai He Sheng Luan Department of Plant and Microbial Biology University of California Berkeley CA 94720 USA School of Biological Sciences (BK21 Program) Chung-Ang University Seoul 156-756 Korea Plant Molecular Biology Institute and College of Life Sciences Nanjing University China WCU Program Chonnam National University Gwangju Korea

Plant hormone abscisic acid （ABA） serves as an integrator of environmental stresses such as drought to trig-ger stomatal closure by regulating specific ion channels in guard cells. We previously reported that SLAC1, an outward anion channel required for stomatal closure, was regulated via reversible protein phosphorylation events involving ABA signaling components, including protein phosphatase 2C members and a SnRK2-type kinase （ost1）. In this study, we reconstituted the ABA signaling pathway as a protein-protein interaction relay from the PYL/RcaR-type receptors, to the PP2C-SnRK2 phosphatase-kinase pairs, to the ion channel SLAC1. The ABA receptors interacted with and inhibited PP2C phosphatase activity against the SnRK2-type kinase, releasing active SnRK2 kinase to phosphorylate, and activate the SLAC1 channel, leading to reduced guard cell turgor and stomatal closure. Both yeast two-hybrid and bimolecular fluorescence complementation assays were used to verify the interactions among the components in the pathway. These biochemical assays demonstrated activity modifications of phosphatases and kinases by their interaction partners. The SLAC1 channel activity was used as an endpoint readout for the strength of the signaling pathway, depending on the presence of different combinations of signaling components. Further study using transgenic plants overexpressing one of the ABA receptors demonstrated that changing the relative level of interacting partners would change ABA sensitivity.

关键词： abscisic acid ABA receptor protein kinase protein phosphatase SLAC1.

经皮穿刺椎间盘内注射乙醇胶髓核溶解术在难治性坐骨神经痛的保守治疗的队列研究

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国际医学放射学杂志 2016年第1期 92-92页

作者： S.Touraine J.Damiano O.Tran J.D.Laredo 梁静 Radiologie ostéo-Articulaire Hpital Lariboisière

摘要目的研究保守治疗失败后经皮穿刺注射乙醇胶髓核溶解术在缓解椎间盘突出造成坐骨神经痛的治疗效果。材料与方法 42例病人保守治疗失败后,在透视引导下行经皮穿刺注射乙醇胶的手术。病人纳入标准:1根据可视疼痛模拟标尺(VAS),病人至... 详细信息

摘要目的研究保守治疗失败后经皮穿刺注射乙醇胶髓核溶解术在缓解椎间盘突出造成坐骨神经痛的治疗效果。材料与方法 42例病人保守治疗失败后,在透视引导下行经皮穿刺注射乙醇胶的手术。病人纳入标准:1根据可视疼痛模拟标尺(VAS),病人至少6周坐骨神经痛大于4/10;2依据MRI或CT检查,病人椎间盘突出小于3个月。VAS评分系统确定基线、1个月后和3个月后的疼痛程度;评估病人相关因素(年龄、性别、疼痛的持续时间)对于经皮穿刺注射乙醇胶髓核溶解术结果的影响,并评估椎间盘突出的相关因

关键词：溶解术椎间盘突出脊柱病经皮穿刺髓核坐骨神经痛保守治疗酒醇一元醇乙醇

视神经脊髓炎病人脊髓病变:MRI长期随访的回顾性研究

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国际医学放射学杂志 2009年第6期 607-607页

作者： Krampla W Aboul-Enein F Jecel J Lang W Fertl E Hruby W 王东烨 Department of Radiology SMZ-Ost Donauspital1220Langobardenstrasse 122ViennaAustria

视神经脊髓炎(neuromyelitis optica,NMO)是以视经和脊髓特殊病变类型而具特征的。有关NMO脊髓病变长期MRI随访研究很罕见,或仅有短期观察报道。对9例诊为NMO或复发性纵向广泛性横贯脊髓炎(longitudinallyxtensive transverse myelitis,... 详细信息

视神经脊髓炎(neuromyelitis optica,NMO)是以视经和脊髓特殊病变类型而具特征的。有关NMO脊髓病变长期MRI随访研究很罕见,或仅有短期观察报道。对9例诊为NMO或复发性纵向广泛性横贯脊髓炎(longitudinallyxtensive transverse myelitis,LETM)伴

关键词： MRI 征象视神经脊髓炎脊髓病变回顾性研究病人长期随访

动脉内注射微粒型类固醇对小鼠模型微血管灌注的毒性作用

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国际医学放射学杂志 2016年第4期 437-437页

作者： E.Laemmel N.Segal M.Mirshahi D.Azzazene S.Le Marchand M.Wybier 董帜 Service de Radiologie ostéoarticulaire Hpital Lariboisière

摘要目的采用活体显微镜研究几种微粒型类固醇药物对活体小鼠模型微血管灌注的作用,并探讨这些微粒型类固醇药物与红细胞在体外的相互作用。材料与方法本研究符合国家动物实验伦理委员会的指南要求。采用活体显微镜检查小鼠提睾肌,对几... 详细信息

摘要目的采用活体显微镜研究几种微粒型类固醇药物对活体小鼠模型微血管灌注的作用,并探讨这些微粒型类固醇药物与红细胞在体外的相互作用。材料与方法本研究符合国家动物实验伦理委员会的指南要求。采用活体显微镜检查小鼠提睾肌,对几种微粒型类固醇对在体微血管灌注的

关键词：小鼠模型微血管类固醇微粒

CT引导经皮穿刺激光凝固治疗手和足的骨样骨瘤

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国际医学放射学杂志 2009年第1期32卷 92-92页

作者： L. Zouari V. Bousson B. Hamzé E. Roulot F. Roqueplan J. D. Laredo 鞠志国 Service de Radiologie ostéo-Articulaire Höpital Lariboisière Paris France

除了在手、足等小管状骨以外，CT引导下经皮穿刺局部消融治疗骨样骨瘤已能在很大程度上替代外科手术。本研究目的是描述CT引导经皮穿刺激光凝固法治疗的15例手和足的骨样骨瘤的技术特点和CT结果。回顾性分析1994--2004年间在本院就诊的... 详细信息

除了在手、足等小管状骨以外，CT引导下经皮穿刺局部消融治疗骨样骨瘤已能在很大程度上替代外科手术。本研究目的是描述CT引导经皮穿刺激光凝固法治疗的15例手和足的骨样骨瘤的技术特点和CT结果。回顾性分析1994--2004年间在本院就诊的经CT引导下行激光凝固治疗的15例病人的医疗病历。

关键词：骨样骨瘤手足激光凝固法

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