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Neural Regeneration Research 2024年第6期19卷 1199-1200页

作者： Francesco Margiotia Lorenzo Di Cesare Mannelli Antonino Morabito Carla Ghelardini Elena Lucarini department of Neuroscience Psychology Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section University of Florence department of Neuroscience Psychology Drug Research and Child Health-NEUROFARBA University of Florence 3. Meyer Children's Hospital IRCCS

Abdominal pain is a common symptom associated with irritable bowel syndrome and inflammatory bowel diseases(IBDs), affecting about 20% of the global population(Grundy et al., 2019). Current pain therapies are poorly effective on visceral pain of intestinal origin and present several side effects, hence the need to identify novel molecular and cellular targets for drug development. The pathophysiology of visceral-abdominal pain,

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The role of green industrial transformation in mitigating carbon emissions:Exploring the channels of technological innovation and environmental regulation

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Energy and Built Environment

Energy and Built Environment 2024年第3期5卷 464-479页

作者： Saima Mehmood Khalid Zaman Shiraz Khan Zohaib Ali Haroon ur Rashid Khan department of Economics The University of HaripurHaripurKhyber Pakhtunkhwa 22620Pakistan department of Management Sciences The University of HaripurHaripurKhyber Pakhtunkhwa 22620Pakistan department of Energy and Process Engineering(EPT) Norwegian University of Science and TechnologyHøgskoleringen 1Trondheim 7034Norway Faculty of Business The University of Wollongong in DubaiDubai 20183United Arab Emirates

The industrial sector is vital to economic progress,yet industrial pollution poses environmental and economic *** purpose of the study was to investigate the influence of green industrial transformation in re-ducing Pakistan’s carbon intensity between 1975 and *** emissions are considered an endogenous construct,while foreign direct investment(FDI)inflows,technological innovation,green industrial transforma-tion,environmental legislation,and research and development(R&D)investment are possible *** association between variables is assessed using the robust least-squares *** industrial transforma-tion is connected with lower carbon emissions,yet technical innovation,R&D investment,and inbound FDI raise a country’s carbon *** findings support the pollution haven hypothesis in a *** causality esti-mates indicate that inward FDI contributes to environmental regulations;green industrial transformation directly relates to inbound FDI and R&D expenditures;and technological innovations correspond to inbound FDI,R&D ex-penditures,industrial ecofriendly progression,and environmental *** to the impulse response function,environmental policies are anticipated to have a differential effect on carbon emissions in 2023,2024,2028-2030,while they are likely to decrease in the years 2025-2027 and 2031 ***,inward FDI and technology advancements would almost certainly result in a rise in carbon emissions over *** industrial transitions are projected to result in a ten-year reduction in carbon *** variance decomposi-tion analysis indicates that eco-friendly industrial adaptations would likely have the largest variance error shock on carbon emissions(11.747%),followed by inbound FDI,technological advancements,and regulatory changes,with R&D spending having a minimal impact over ***’s economy should foster a green industrial revolution to avoid pollution and increase environm

关键词： Carbon intensity Industrial green transformation Environmental regulations Technological innovations Robust least squares regression

Sex-specific life-history trait expression in hybrids of a cave- and surface-dwelling fish (Poecilia mexicana, Poecilidae)

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Current Zoology 2024年第4期70卷 421-429页

作者： Rüdiger Riesch Luis R.Arriaga Ingo Schlupp department of Biological Sciences Royal Holloway University of LondonEghamTW20 OEXUK CEFE CNRSUnivMontpellierEPHEIRDMontpellierFrance department of Biology University of OklahomaNormanOK 73019USA

Evaluating the fitness of hybrids can provide important insights into genetic differences between species or diverging *** focused on surface-and cave-ecotypes of the widespread Atlantic molly Poecilia mexicana and raised F1 hybrids of reciprocal crosses to sexual maturity in a common-garden *** were reared in a fully factorial 2 x 2 design consisting of lighting(light ***)and resource availability(high *** food).We quantified survival,ability to realize their full reproductive potential(i.e.,completed maturation for males and 3 consecutive births for females)and essential life-history *** to the performance of pure cave and surface fish from a previous experiment,F1s had the highest death rate and the lowest proportion of fish that reached their full reproductive *** also uncovered an intriguing pattern of sex-specific phenotype expression,because male hybrids expressed cave molly life histories,while female hybrids expressed surface molly life *** results provide evidence for strong selection against hybrids in the cave molly system,but also sug-gest a complex pattern of sex-specific(opposing)dominance,with certain surface molly genes being dominant in female hybrids and certain cavemollygenes beingdominant in malehybrids.

关键词： dominance life-history evolution local adaptation postzygotic isolation selection against hybrids.

The interaction between stock prices and interest rates in Turkey:empirical evidence from ARDL bounds test cointegration

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Financial Innovation 2019年第1期5卷 110-121页

作者： Turgut Tursoy department of banking and Finance Near East UniversityNicosia99138North Cyprus10 MersinTurkey

This paper demonstrates a significant,long-running relationship between stock prices and domestic interest rates in Turkey’s financial markets for the period of 2001 M1-2017 *** analysis is investigated using the autoregressivedistributed lag bounds(ARDL Bounds)test and vector autoregressive ***,cointegrating equations such as the fully modified ordinary least square,dynamic ordinary least squares,and canonical cointegrating regression are applied to check the long-run elasticities in the concerned *** ARDL Bounds and Johansen Cointegration test results show that,dynamically,both prices are significantly related to each *** cointegrating equation outcomes demonstrate elasticities whereby both coefficients have negative ***,the same results are corroborated by the impulse response where all variables respond negatively to each other.

关键词： Stock price Interest rates Cointegration ARDL VAR

Glucocorticoids-based prodrug design: Current strategies and research progress

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Asian Journal of Pharmaceutical Sciences 2024年第3期19卷 45-82页

作者： Hongbing Liu Muse Jia Peifu Xiao Jingxin Gou Tian Yin Haibing He Xing Tang Yu Zhang department of Pharmaceutics Shenyang Pharmaceutical University School of Chinese Materia Medica Shenyang Pharmaceutical University

Attributing to their broad pharmacological effects encompassing anti-inflammation,antitoxin, and immunosuppression, glucocorticoids(GCs) are extensively utilized in the clinic for the treatment of diverse diseases such as lupus erythematosus, nephritis,arthritis, ulcerative colitis, asthma, keratitis, macular edema, and leukemia. However, longterm use often causes undesirable side effects, including metabolic disorders-induced Cushing's syndrome(buffalo back, full moon face, hyperglycemia, etc.), osteoporosis,aggravated infection, psychosis, glaucoma, and cataract. These notorious side effects seriously compromise patients' quality of life, especially in patients with chronic ***, glucocorticoid-based advanced drug delivery systems for reducing adverse effects have received extensive attention. Among them, prodrugs have the advantages of low investment, low risk, and high success rate, making them a promising *** this review, we propose the strategies for the design and summarize current research progress of glucocorticoid-based prodrugs in recent decades, including polymer-based prodrugs, dendrimer-based prodrugs, antibody-drug conjugates, peptide-drug conjugates,carbohydrate-based prodrugs, aliphatic acid-based prodrugs and so on. Besides, we also raise issues that need to be focused on during the development of glucocorticoid-based prodrugs. This review is expected to be helpful for the research and development of novel GCs and prodrugs.

关键词： Glucocorticoids Prodrug design Targeted drug delivery Research progress

Does financial development lower energy intensity?

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Frontiers in Energy 2020年第3期14卷 620-634页

作者： Philip Kofi ADOM Michael Owusu APPIAH Mawunvo Prosper AGRADI department of Development Policy School of Public Service and GovernanceGhana Institute of Management and Public Administration(GIMPA)AchimotaGhana department of Finance Business SchoolUniversity of Cape CoastAccraGhana department of banking and Finance University of Professional StudiesAccraGhana

The growth-induced effects of financial development have been well-established in the empirical literature,as well as the significance of financial development to energy demand ***,the empirical evidence on the relationship between financial development and energy intensity remains sparse in the *** the multifaceted nature of the effects of financial development,the proposed relationship seems a complex one and warrants an empirical *** the case of Ghana,this study provides an empirical answer to the question:does financial development lower energy intensity?To provide solid grounds for either rejection or acceptance of the null hypothesis,this study performed several robustness ***,the evidence revealed that financial development lowers energy ***,the results revealed that the price of energy,trade liberalization and industry structure play significant *** results have important implications for the design of macro energy efficiency policies and the creation of a‘Green Bank’.

关键词： financial development energy intensity energy efficiency Ghana

Preparation and desulfurization activity of nano-CeO_2/γ-Al_2O_3 catalysts

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Rare Metals 2018年第7期37卷 554-560页

作者： Qi Yang Hui Hu Shan-Shan Wang School of Environment Science and Engineering Huazhong University of Science and Technology department of Urban Construction Wuchang Shouyi University Wuhan Zuoling New Town Development and investment Co. Ltd.

γ-A12O3-supported CeO2 catalysts were pre- pared by microemulsion and impregnation methods and characterized by X-ray diffraction （XRD） and scanning electron microscope （SEM） techniques. At the same time, the desulfurization activity of catalysts was investigated. The results show that nanoscale active substances and a high desulfurization effect are achieved by microemulsion, exhibiting a significant dominance compared with traditional impregnation method. The optimal preparation condition is temperature of 30 ℃ and ratio of [H20]/[surface active agent] of 7 with slow demulsification. The activated catalysts still keep high and stable desulfurization activity during a wide temperature range of 450-600 ℃. Among a series of prepared catalysts, the desulfurization rate of 6CeOz/γ-A1203 is the highest, reaching up to 80 % when temperature is higher than 550℃. The catalytic reduction mechanism of SO2 over nano-CeOz/γ-A1203 follows redox mechanism.

关键词： Nano-CeO2/γ-Al2O3 Microemulsion Catalyst Desulfurization

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Adjustment and Institutional Innovation of the New Third Board in China

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China Economic Transition 2018年第3期1卷 112-118页

作者： SONG Guoliang ZHANG Yajing Research Center of Financial Products and investment University of International Business and Economics School of banking&Finance University of International Business and Economics

The new third board(NTB)is an important part of multi-level capital markets in China In 2018,capital markets in China continues to develop along the underlying principle of pursuing progress while ensuring stability,and fulfills the three missions of serving the real economy,preventing risks,and deepening *** will promote the healthy,quality development of multi-level capital *** the National Equities Exchange and Quotations or the NTB will play an important role.

关键词： capital deepening Institutional

Elements Enrichment Characteristics in Interfacial Transition Zone of MgO Concrete

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Wuhan University Journal of Natural Sciences 2013年第1期18卷 88-92页

作者： CHEN Xia ZHAO Wei LI Pengxiang department of Materials and Structure Changjiang River Scientific Research Institute China Power investment Incorporation

Microscopic techniques were employed to investigate element enrichment characteristics in the vicinity of the interracial transition zone （[TZ） of MgO concrete. Results indicated that the morphology of products of hydration in 1TZ was similar to the cement matrix but different by amount, size and crystal features. Elements Ca, Si, AI and Mg were obviously enriched in ITZ and uniformity of their distribution grew with age. MgO was non- uniformly distributed in concrete, accounting for 8.47% and 4.53% respectively in paste and ITZ area despite of fully mixture in construction, yet MgO showed inclination of migrating towards ITZ area with in-depth hydration and the gap in between was mit- igated from 3.94% at 7 d to 1.31% at 240 d so far as 5% of light- burnt MgO was incorporated.

关键词： MgO interracial transition zone elements enrich-ment distribution

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AJAC: Atomic data calculation tool in Python

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Chinese Physics B 2013年第4期22卷 545-557页

作者： Amani Tahat Jordi Marti Kaher Tahat Ali Khwaldeh department of Physics and Nuclear Engineering Technical University of Catalonia Barcelona Spain Saudi Grown investment Company Quai du Seujet 30 Geneva 1201 Switzerland department of Computer Engineering Faculty of Engineering Philadelphia University Amman Jordan

In this work, new features and extensions of a currently used online atomic database management system are reported. A multiplatform flexible computation package is added to the present system, to allow the calculation of various atomic radiative and collisional processes, based on simplifying the use of some existing atomic codes adopted from the literature. The interaction between users and data is facilitated by a rather extensive Python graphical user interface working online and could be installed in personal computers of different classes. In particular, this study gives an overview of the use of one model of the package models （i.e., electron impact collisional excitation model）. The accuracy of computing capability of the electron impact collisional excitation in the adopted model, which follows the distorted wave approximation approach, is enhanced by implementing the Dirac R-matrix approximation approach. The validity and utility of this approach are presented through a comparison of the current computed results with earlier available theoretical and experimental results. Finally, the source code is made available under the general public license and being distributed freely in the hope that it will be useful to a wide community of laboratory and astrophysical plasma diagnostics.

关键词： software engineering atomic data atomic databases

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