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Journal of Mechanics Engineering and Automation 2014年第5期4卷 432-440页

作者： luiz Henrique Melo Silva Nobrega Verilton Nunes da Silva Jose Carlos de Lima Junior Joao Bosco de Aquino Silva Igor Lucena Peixoto Andrezza Rafael Franklin Alves Silva Department of Mechanical Engineering Federal University of Paraiba Jo6o Pessoa 58051-900 Brazil Department of Mechanical Engineering Federal Institute of Bahia SimOes Filho 43700-000 Brazil Informatics Center Federal University of Paraiba Jo6o Pessoa 58051-900 Brazil Department of Mechanical Engineering Federal Institute of Paraiba Jo6o Pessoa 58900-000 Brazil

Psychopharmacological Profile of Hydroalcoholic Extract and P-Hydroxybenzoic Acid obtained from <i>Bourreria huanita</i>(Boraginaceae) in Mice

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Pharmacology & Pharmacy 2014年第11期5卷 983-995页

作者： Iandra Holzmann Daiane Cattani Micheli Corso Daiane Perondi Sabrina Zanella Cristiani Burger luiz Carlos Klein Júnior Valdir Cechinel Filho Sully M. Cruz Miguel F. Torres Armando Cáceres Márcia Maria de Souza Programa de Pós-Graduação em Ciências Farmacêuticas Universidade do Vale do Itajaí Itajaí Brazil Núcleo de Investigações Químico Farmacêuticas Universidade do Vale do Itajaí Itajaí Brazil Facultad de CCQQ y Farmacia Universidad de San Carlos Guatemala City Guatemala

Bourreria huanita (Lex.) Hemsl. (Boraginaceae) is a very rare and highly appreciated tree in Mesoamerica for its medicinal properties and beauty. It grows in a region extending from central Mexico to Costa Rica. Ethnobotanical surveys have shown that the infusion of dried flowers is popularly used as a tranquilizer to cure several diseases. In the present study we report the isolation of p-hydroxybenzoic acid (pHBZ) obtained from the hydroalcoholic extract (HE) of B. huanita, and the effect of both, the extract and the compound on the central nervous system in mice. HE of B. huanita (100, 150, 300 mg/kg) and pHBZ (10 mg/kg) were orally administered to mice and 1 h later, behavioral tests were performed. The effects of HE and pHBZ were tested by pentylenetetrazole (PTZ) and strychnine (STR) induced seizures, pentobarbital-induced hypnosis, the forced swimming test and the tail suspension test, the elevated plus maze, apomorphine-induced stereotypy and the climbing test, the inhibitory avoidance test and the open-field test. B. huanita extract produced hypnotic, anxiolytic and antidepressant effects in animals, with no change in motor performance. on the other hand, the extract did not reduce PTZ and STR-induced convulsions, apomorphine-induced stereotypy or climbing. Moreover, no changes were observed in the animals’ memory. The compound pHBZ was effective only in the depression tests. The results obtained in the present study suggest that B. huanita exhibited sedative, antidepressant and hypnotic activities in mice, and that the antidepressant activity may be mediated by an isolated compound identified as pHBZ.

关键词： Bourreria huanita Antidepressant Sedative and Hypnotic Activities P-Hydroxybenzoic Acid

Reality named endoscopic ultrasound biliary drainage

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World Journal of Gastrointestinal Endoscopy 2015年第15期7卷 1181-1185页

作者： Hugo Goncalo Guedes Roberto Iglesias Lopes Joel Fernandez de oliveira Everson luiz de Almeida Artifon Department of Surgery University of Sao Paulo Medical School Division of Gastrointestinal Endoscopy University of S?o Paulo Medical School

Endoscopic ultrasound(EUS) is used for diagnosis and evaluation of many diseases of the gastrointestinal (GI) tract. In the past, it was used to guide a cholangio-graphy, but nowadays it emerges as a powerful thera-peutic tool in biliary drainage. The aims of this review are: outline the rationale for endoscopic ultrasound-guided biliary drainage(EGBD); detail the procedural technique; evaluate the clinical outcomes and limitations of the method; and provide recommendations for the practicing clinician. In cases of failed endoscopic retro-grade cholangiopancreatography(ERCP), patients are usually referred for either percutaneous transhepatic biliary drainage(PTBD) or surgical bypass. Both these procedures have high rates of undesirable complications. EGBD is an attractive alternative to PTBD or surgery when ERCP fails. EGBD can be performed at two locations: transhepatic or extrahepatic, and the stent can be inserted in an antegrade or retrograde fashion. The drainage route can be transluminal, duodenal or trans-papillary, which, again, can be antegrade or retrograde [rendezvous(EUS-RV)]. Complications of all techniques combined include pneumoperitoneum, bleeding, bile leak/peritonitis and cholangitis. We recommend EGBD when bile duct access is not possible because of failed cannulation, altered upper GI tract anatomy, gastric outlet obstruction, a distorted ampulla or a periampullary diverticulum, as a minimally invasive alternative to surgery or radiology.

关键词： Endoscopic ultrasound Rendezvous Biliary drainage obstrutive cancer Papillary obstrution

Effect of Microfocused Ultrasound on Facial Rejuvenation: Clinical and Histological Evaluation

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Journal of Biosciences and Medicines 2021年第7期9卷 112-125页

作者： Patricia Froes Meyer Michelle Meleck Fabio dos Santos Borges Esteban Fortuny Stephany Luanna Queiroga Farias Felipe Alexander Caldas Afonso Ciro Dantas Soares Eneida de Morais Carreiro Rodrigo Marcel Valentim da Silva André luiz Miranda Barbosa Federal University of Rio Grande do Norte (UFRN) Natal Brazil University Centre of Rio Grande do Norte (UNI-RN) Natal Brazil Michelle Meleck Advanced Aesthetics S&atilde o Paulo Brazil Estácio de Sá University Rio de Janeiro Brazil Universidad Finis Terrae Santiago Chile Potiguar University (UNP) Natal Brazil Campinas State University (UNICAMP) Campinas Brazil Fellow da West Virginia University Morgantown USA

Introduction: Micro focused ultrasound (MFU) is formed by mechanical waves emitted in a focused manner, concentrating thermal energy on a certain point or region, promoting a clinical improvement in wrinkles. objective: evaluate the effects of micro focused ultrasound on facial rejuvenation. Methodology: This is an experimental study. The sample consisted of 30 volunteers, who were evaluated before treatment, 45 and 90 days after its beginning. A single application of the MFU was performed across the facial region. The parameters used were: 10 MHz cartridge with depth of 1.5 mm, 7 MHz with depth of 3 mm, and 4 MHz with focal depth of 4.5 mm;doses ranged from 0.1 to 2.0 J, according to the sensitivity of the volunteers treated, and the application time was of approximately 90 minutes. Clinical photographic analysis and facial symmetry analysis using Dolphin Imaging software were performed, and validated questionnaires. Two volunteers were submitted to blepharoplasty surgery, and one to rhytidoplasty surgery 45 days after the application of the MFU. Samples of the treated skin were taken after the surgical procedures and submitted to histological and immunohistochemical analyses. The volunteers answered a questionnaire to assess adverse reactions and satisfaction. Results: We observed a visible clinical improvement on the images by photography, and an improvement of facial symmetry in the measurements of the paralateronasal projection (p = 0.007), left lateral mandibular (p = 0.01), and right lateral mandibular (p = 0.008). The histological analysis showed an increase in the amount of fibroblasts (p = 0.02), blood vessels (p = 0.0062) and inflammatory cells (p = 0.0036), in addition to the production of type 1 collagen. In the immunohistochemical analysis, we observed the presence of the macrophage marker IHQ: CD68, indicating phagocytosis of adipose tissue and the presence of fibrosis. In the analysis of adverse reactions, only transient hyperemia was observed with t

关键词： Skin Aging Mechanical Waves Sagging Wrinkles

Decreased prevalence of celiac disease among Brazilian elderly

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World Journal of Gastroenterology 2013年第12期19卷 1930-1935页

作者： Lucas Malta Almeida luiz Claudio Castro Rosa Harumi Uenishi Fernanda Coutinho de Almeida Patricia Maria Fritsch Lenora Gandolfi Riccardo Pratesi Yanna Karla de Medeiros Nóbrega Graduate Program in Medical Sciences University of Brasilia School of Medicin Doctoral fellow of Coordenao de Aperfeioamento de Pessoal de Nível Superior Graduate Program in Health Sciences University of Brasilia School of Health Sciences Research Center for Celiac disease University of Brasilia School of Medicine Department of Pharmaceutical Sciences University of Brasilia School of Health Sciences Research Center for Celiac Disease University of Brasilia School of Medicine

AIM: To evaluate the prevalence of celiac disease in a group of Brazilian individuals over 60 years of age and compare it with the previously known prevalence in a pediatric group living in the same geographical ***: The research protocol was approved by the Ethics Committee of the University of Brasilia School of Medicine, Brasilia, Brazil. Blood samples from 946 individuals (295 male and 651 female) aged 60 years or older were collected between May 2010 and July 2011. The study subjects' mean and median ages were 68.1 and 67 years, respectively, ranging from 60 to 92 years. That age distribution closely corresponded to the age distribution of the Brazilian population according to the Brazilian 2010 census. The participants were consecutive and unselected outpatients undergoing blood tests at the University of Brasilia Hospital's Clinical Pathology Laboratory. All sera were tested for immunoglobulin A anti-transglutaminase antibodies (IgA-tTG) by enzymelinked immunosorbent assay, and those that were positive were further tested for immunoglobulin A antiendomysium antibodies (IgA-EMA). Human leukocyte antigen (HLA) genotyping was performed for all individuals who exhibited positive serologic results for IgA-tTG and/or ***: out of the 946 studied patients, only one previously diagnosed case of biopsy-proven celiac disease was detected. For the remaining subjects, nine serum samples tested positive for IgA-tTG antibodies; however, none of them tested positive for IgA-EMA antibodies. The HLA genotyping of those nine subjects revealed that one was carrying DQA1*0501 and two were carrying DQB1*0201 alleles. These data showed that, among those 946 elderly individuals, the prevalence of celiac disease (CD) was 0.1% (95%CI: 0.00-0.59). The prevalence of CD for the elderly group was compared with that observed for the group of 2034 children younger than 15 years (age range, 1-14 years; mean age, 8 years) who took part in our previous CD prevalence screen

关键词： Celiac disease Gluten-sensitive enteropathy Epidemiology Elderly Mortality

Physicochemical and Thermal Characterization of the Spirulina platensis

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Journal of Agricultural Science and Technology(B) 2020年第5期10卷 298-307页

作者： Anny Manrich Juliano Elvis de oliveira Maria Alice Martins luiz Henrique Capparelli Mattoso Nanotechnology National Laboratory for Agriculture(LNNA) Embrapa InstrumentaçãoRua XV de Novembro 1452São Carlos 13561-206SPBrazil Engenharia de Materiais Departamento de EngenhariaUniversidade Federal de LavrasAv.Doutor Sylvio Menicucci1001Lavras 37200-900MGBrazil

Cyanobacterium Spirulina platensis is commercially produced as a nutrient source for food,animal feed and pharmaceutical industries,and is also explored in other applications in areas such as material sciences,materials engineering and for the production of biofuels and *** to the increasing interest in the use of this microalga,a complete characterization was intended,as to provide data to the insufficient *** this work,various techniques were used for thermal(thermogravimetric analysis(TGA)/derivative thermogravimetry(DTG),differential scanning calorimetry(DSC)),structural(scanning electron microscopy(SEM)and wide-angle X-ray diffraction(XRD))and chemical(atomic absorption spectroscopy(AAS),attenuated total reflection Fourier transform infrared spectroscopy(ATR-FTIR),energy dispersive X-ray spectroscopy(EDX))characterization of Spirulina cultivated in *** have shown that in addition to the high quantity of protein(over 50%),Brazilian Spirulina is a source for carbohydrates(33%)and also has good thermal stability up to 200°*** pigment protein Phycocyanin could be identified by FTIR and ultraviolet-visible(UV-vis)*** show favorable properties of Spirulina as a source for new materials and biomass.

关键词： Spirulina platensis characterization blue-green algae chemical composition amino acids

Effects of Rate, Time and Splitting of Nitrogen Fertilization on the Technological Quality of Wheat

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Journal of Food Science and Engineering 2013年第1期3卷 9-18页

作者： LidianeBorgesDias de Moraes Janete Deliberali Freo Barbara Biduski Moacir Cardoso Elias luiz Carlos Gutkoski Department of Agroindustrial Science and Technology/DCTA-Federal University of Pelotas/UFPel P.O. Box 354 Cap6o do Le6oCEP 96010900 RS Brazil Food Research Center University of Passo Fundo/UPF BR 285 Passo Fundo CEP 99052900 RS Brazil

Northeastern Brazilian Marine Atmospheric Corrosion Performances of Galvanized Steel and Copper Specimens

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Journal of Chemistry and Chemical Engineering 2011年第5期5卷 435-442页

作者： Kelly Jacqueline Campos Brambilla Princia Aparecida Morais Pereira Kleber Franke Portella Paulo CosarInone Fernando Piazza Jose Maurilio da Silva Guilherme Cunha da Silva Sergio luiz Henke Mairio Seixas Cabussu Dailton Pedreira Cerqueira Rogerio Nascimento Salles Instituto de Tecnologia para o Desenvolvimento Departamento de Materiais Curitiba Parandz PoBox： 19067 81531-980 Brazil Companhia de Eletricidade da Bahia COELBA Departamento de Engenharia de Manuten96o Granjas Rura~ Pres. Vargas s/nSalvador BA 41.290-000 Brazil

optimal Placement of Phasor Measurement Units Using a Modified Canonical Genetic Algorithm for observability Analysis

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Journal of Mechanics Engineering and Automation 2014年第3期4卷 187-194页

作者： Rodrigo Albuquerque Frazao Aureio luiz Magalhfies Denisson oliveira Shigeaki Lima Igor Santos Grenoble Electrical Engineering Laboratory Grenoble Institute of Technology Grenoble 38402 France Institute of Electrical Power Svstems. Federal University ofltaiub6. Itaiub6 37500-903. MG. Brazil Institute of Electrical Engineering Federal University of Maranh6o S6o Luis 65080-040 MA Brazil

This paper proposes a method for optimal placement of synchronized PMUs (phasor measurement units) in electrical power systems using a MCGA (modified canonical genetic algorithm), which the goal is to determine the minimum number of PMUs, as well as the optimal location of these units to ensure the complete topological observability of the system. In case of more than one solution, a strategy of analysis of the design matrix rank is applied to determine the solution with the lower number of critical measurements. In the proposed method of placement, modifications are made in the crossover and mutation genetic operators, as well as in the formation of the subpopulation, and are considered restrictive hypotheses in the search space to improve the performance in solving the optimization problem. Simulations are performed using the IEEE 14-bus, IEEE 30-bus and New England 39-bus test systems. The proposed method is applied on the IEEE 118-bus test system considering the presence of observable zones formed by conventional measurements.

关键词：相量测量单元可观测性分析经典遗传算法优化配置修改 IEEE 最佳位置电力系统

The Ability of Nile Tilapia to Regulate Protein and Energy Intake Evaluated by Carbon Relative Enrichment （δ^13C）

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Journal of Agricultural Science and Technology(B) 2013年第1期3卷 45-55页

作者： André Moreira Bordinhon luiz Edivaldo Pezzato Carlos Ducatti Juliana Céia Denadai Margarida Maria Barros Agriculture and Environment Institute Universidade Federal do Amazonas Humaittá Amazonas 69800-000 Brazil Aquatic organisms Nutrition Laboratory (Aquanutri) College of Veterinary Medicine and Animal Science Sǎo Paulo StateUniversity Botucatu Sǎo Paulo 18610-307 Brasil Environmental Stable lsotopes Center Biosciences Institute Sao Paulo State University Botucatu Sao Paulo 18610-307 Brasil