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Assessing the impact of concurrent high-fructose and highsaturated fat diets on pediatric metabolic syndrome:A review

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World Journal of Clinical Pediatrics 2024年第2期13卷 62-79页

作者： Manuel Alejandro Vargas-Vargas Marcela González-Montoya Olin Torres-Isidro Claudia Isabel García-Berumen Omar Ortiz-Avila Elizabeth Calderón-Cortés Christian Cortés-Rojo Instituto de Investigaciones Químico–Biológicas Universidad Michoacana de San Nicolás de HidalgoMorelia 58030MichoacánMexico Facultad de Enfermería Universidad Michoacana de San Nicolás de HidalgoMorelia 58020MichoacánMexico

High-saturated fat(HF)or high-fructose(HFr)consumption in children predispose them to metabolic syndrome(MetS).In rodent models of MetS,diets containing individually HF or HFr lead to a variable degree of ***,simultaneous intake of HF plus HFr have synergistic effects,worsening MetS *** children,the effects of HF or HFr intake usually have been addressed ***,we have reviewed the outcomes of HF or HFr diets in children,and we compare them with the effects reported in *** humans,HFr intake causes increased lipogenesis,hypertriglyceridemia,obesity and insulin *** the other hand,HF diets promote low grade-inflammation,obesity,insulin *** the deleterious effects of simultaneous HF plus HFr intake on MetS development in rodents,there is little information about the combined effects of HF plus HFr intake in *** aim of this review is to warn about this issue,as individually addressing the effects produced by HF or HFr may underestimate the severity of the outcomes of Western diet intake in the pediatric *** consider that this is an alarming issue that needs to be assessed,as the simultaneous intake of HF plus HFr is common on fast food menus.

关键词： Fructose Saturated fat Metabolic syndrome Insulin resistance Type 2 diabetes Ultra processed foods Children Obesity Dyslipidemia Non-alcoholic fatty liver disease

Systemic Acquired Resistance of Soybean to Soybean Rust Induced by Shale Water

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American Journal of Plant Sciences 2015年第14期6卷 2249-2256页

作者： Yeshwant R. Mehta Mariana S. Marangoni Janaina N. Matos José Marcos G. Mandarino Rafael Galbieri Instituto AgronÔ mico do paraná-iapar Rodovia Celso Garcia Cid Londrina Brazil Embrapa Soja Londrina Brazil Instituto Mato-Grossense do AlgodÃ o (IMA) Primavera do Leste Brazil

Shale water as a by-product obtained by Petrobras, Brazil, during the process of extraction of petroleum from fossil rock may act as an inducer of Systemic Acquired Resistance (SAR) to some plant pathogens. The objective of the present investigation was to verify the effect of seed treatment and foliar application with shale water in inducing SAR of soybean to soybean rust under greenhouse and field conditions. In greenhouse experiments, seed treatment alone with shale water significantly reduced the severity of soybean rust and the control efficiency after 11 and 14 days after inoculation was between 54.1% and 57.8%. Whereas seed treatment and only one foliar application with shale water the control efficiency due to SAR 14 and 11 days after inoculation was between 99.7% and 100%, respectively. Such treatments gave similar results under field experiments where the control efficiency of soybean rust was between 79.0% and 99.35% in shale water treated plots as compared to the untreated plots, in 2015. Consequently, this resulted in yield increase between 14.8% and 28.8% depending upon the seed treatment and foliar applications with shale water alone or in mixture with a fungicide. Seed health testing revealed lower number of seeds infected with some pathogens in treatments where either shale water or fungicide was used. Seed treatment and one foliar application were sufficient to induce SAR against soybean rust. This is the first report to demonstrate SAR of soybean to soybean rust induced by shale water. Patent regarding this investigation is deposited with Petrobras, Brazil, under the number EVP 14/022.

关键词： Glycine max Phakospora pachyrhizi Asian Soybean Rust

Integrative Analysis of Transcriptome and Phenolic Compounds Profile Provides Insights into the Quality of Soursop (Annona muricata L.) Fruit

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1717-1732页

作者： Yolotzin Apatzingán Palomino-Hermosillo Ángel Elpidio Díaz-Jasso Rosendo Balois-Morales Verónica AlhelíOchoa-Jiménez Pedro Ulises Bautista-Rosales Guillermo Berumen-Varela Unidad de Tecnología de Alimentos-Secretaría de Investigación y Posgrado Universidad Autónoma de Nayarit.Ciudad de la Cultura SNTepic63000NayaritMéxico Programa Académico de Biología Unidad Académica de AgriculturaUniversidad Autónoma de NayaritKm.9.Carretera Tepic-CompostelaXalisco63780NayaritMéxico Estancias Posdoctorales-Consejo Nacional de Humanidades Ciencias y TecnologíasCoordinación de Apoyos a Becarios e InvestigadoresDirección de PosgradoCiudad de México03940México

Soursop(Annona muricata L.)is a tropical fruit highly valued for its uniqueﬂavor,nutritional value,and health-promoting *** ripening process of soursop involves complex changes in gene expression and metabo-lite accumulation,which have been studied using various omics *** analysis has provided insights into the regulation of key genes involved in ripening,while metabolic compound analysis has revealed the presence of numerous bioactive compounds with potential health beneﬁ***,the integration of transcrip-tome and metabolite compound data has not been extensively explored in ***,in this paper,we present a comprehensive analysis of the transcriptome and phenolic compound proﬁles of soursop during *** integration analysis showed that the genes and phenolic compounds were mainly involved in the starch and sucrose metabolism pathways during soursop ***,the phenolic compounds Kaempferol 3-Q-galactoside,Procyanidin C1,Procyanidin trimmer C1,and m-Coumaric,as well as the genes Ubiquitin-like protein 5(UBL5_ARATH),ATP-dependent zinc metalloprotease FTSH8(FTSH8_ORYSJ),Zinc transporter 4(ZIP4_AR-ATH),Thioredoxin-like 3-1(TRL31_ORYSJ),Mitogen-activated protein kinase YODA(YODA_ARATH),R-man-delonitrile lyase-like(MGL_ARATH),26s protease regulatory subunit 6A homolog(PRS6_SOLLC),Cytochrome P45072A13(C7A13ARATH),Cytochrome P45084A1(C84A1_ARATH)and Homoserine O-trans-acetylase(MET2-ORYSJ)were correlated and differentially accumulated and expressed,*** study provides new insights into the molecular mechanisms underlying soursop ripening and may contribute to the development of strategies for improving the nutritional quality and shelf life of this important fruit.

关键词： Bioinformatics data integration genes metabolites postharvest storage ripening

Influence of dissolved organic matter character on mercury incorporation by planktonic organisms: An experimental study using oligotrophic water from Patagonian lakes

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Journal of Environmental Sciences 2013年第10期25卷 1980-1991页

作者： María C.Diéguez Claudia P.Queimalios Sergio Ribeiro Guevara Mark Marvin-DiPasquale Carolina Soto Crdenas María A.Arribre Laboratorio de Fotobiología INIBIOMA CONICET-UNComahue Laboratorio de Fotobiolog INIBIOMA CONICET-UNComahue Laboratorio de Anlisis por Activación Neutrónica Centro Atómico Bariloche CNEA United States Geological Survey Laboratorio de Anlisis por Activacio Neutrónica Centro Atómico Bariloche CNEA

Ligands present in dissolved organic matter （doM） form complexes with inorganic divalent mercury （Hg^2＋） affecting its bioavailability in pelagic food webs. This investigation addresses the influence of a natural gradient of doM present in Patagonian lakes on the bioaccumulation of Hg^2＋（the prevailing mercury species in the water column of these lakes） by the algae Cryptomonas erosa and the zooplankters Brachionus calyciflorus and Boeckella antiqua. Hg^2＋ accumulation was studied through laboratory experiments using natural water of four oligotrophic Patagonian lakes amended with^197Hg^2＋. The bioavailability of Hg^2＋ was affected by the concentration and character of doM. The entrance of Hg^2＋ into pelagic food webs occurs mostly through passive and active accumulation. The incorporation of Hg^2＋ by Cryptomonas, up to 27% of the Hg^2＋ amended, was found to be rapid and dominated by passive adsorption, and was greatest when low molecular weight compounds with protein-like or small phenolic signatures prevailed in the doM. Conversely, high molecular weight compounds with a humic or fulvic signature kept Hg^2＋ in the dissolved phase, resulting in the lowest Hg^2＋ accumulation in this algae. In Brachionus and Boeckella the direct incorporation of Hg from the aqueous phase was up to 3% of the Hg^2＋ amended. The dietary incorporation of Hg^2＋ by Boeckella exceeded the direct absorption of this metal in natural water, and was remarkably similar to the Hg^2＋ adsorbed in their prey. Overall, doM concentration and character affected the adsorption of Hg^2＋ by algae through competitive binding, while the incorporation of Hg^2＋ into the zooplankton was dominated by trophic or dietary transfer.

关键词： mercury dissolved organic matter plankton mercury incorporation Patagonian lakes Argentina

Deciphering the fiber quality of Gossypium barbadense *** in La Convención,Cusco,Perú

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Journal of Cotton Research 2024年第3期7卷 231-242页

作者： MORALES-ARANIBAR Luis SAENZ Manuel Canto MORALES-ARANIBAR Carlos Genaro RIVERA Marite Yulisa Nieves AGUILERA Jorge González STEINER Fábio BARDIVIESSO Diógenes Martins ZUFFO Alan Mario National Intercultural University of Quillabamba Cusco 08741Peru Universidad Nacional Agraria La Molina(UNALM) Lima 012Peru Graduate School Jorge Basadre Grohmann National UniversityTacna 583000Peru National Institute of Agrarian Innovation(INIA) Lima 15024Peru Department of Agronomy State University of Mato Grosso do Sul(UEMS)Cassilândia 79540‑000MSBrazil Department of Agronomy State University of Maranhão(UEMA)Balsas 65800‑000MABrazil

Background The quality of cotton fiber determines its value in the textile market,influencing agricultural profitability and the efficiency of textile *** selection of genotypes with superior fibers is a key factor for genetic improvement programs seeking adaptability and sustainability in the face of climate *** demonstrates the strategic importance of this plant for sustainable agriculture and the global textile *** objective of this research was to decipher the fiber quality of Gossypium barbadense *** in the native Amazonian communities of La Convención,Cusco-Perú,and to evaluate other critical aspects of native cotton that have not yet been *** methodology included non-probability sampling for accessibility,qualitative and quantitative analyses,and multivariate *** fiber length(mm),micronaire index(maturity/fineness),fiber strength(gf/tex),length uniformity index(%),fiber elongation(%),maturation index(%),and short fiber index(%)were the fiber characteristics evaluated using the HVI method in cotton *** Cotton accessions collected from Koribeni(Gossypium spp.)and Shivankoreni(Gossypium barbadense ***)stood out for their fiber quality properties,especially length,strength,and uniformity,which highlights their relevance for advanced textile applications and potential for use in plant genetic improvement *** These findings reinforce the need to conserve and study these native cotton accessions from the Peruvian Amazon region,which can offer promising perspectives for the textile industry and agricultural biodiversity.

关键词： Cotton Sustainability Amazonian communities Cotton fiber quality

Dynamics in the emergence of dormant and non-dormant herbaceous species from the soil seed bank from a Brazilian dry forest

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Journal of Plant Ecology 2020年第3期13卷 256-265页

作者： José Djalma de Souza Bruno Ayron de Souza Aguiar Danielle Melo dos Santos Vanessa Kelly Rodrigues de Araujo Júlia Arruda Simões Juliana Ramos de Andrade Elcida de Lima Araújo Departamento de Biologia Universidade Federal Rural de PernambucoRecifePernambucoBrazil2Universidade Federal de Pernambuco-Centro Acadêmico de VitóriaPernambucoBrazil

Aims In dry tropical forests,herbaceous species may have dormancy mechanisms and form persistent and transient seed banks in the *** acquired,these mechanisms are efficient for the establishment and survival of these herbs,especially in forests with unpredictable climates,such as the ***,our objective was to verify whether the studied herbaceous species adopt the physical dormancy mechanism and how these natural barriers are overcome,to understand the temporal dynamics existing in the soil seed bank from a Brazilian dry tropical *** Seeds of five native herbaceous species from the Caatinga forests were selected and submitted to pre-germinative treatments for verifying the presence of physical *** collected soil samples in the rainy and dry seasons for four consecutive years and monitored the emergence of the selected herbaceous in the *** verified the differences in germination and seed bank emergence in the soil by generalized linear *** Findings The presence and absence of physical dormancy were observed in seeds from Caatinga herbaceous *** found intraspecific and interspecific differences in the herbaceous emergence from soil seed banks between years and climatic *** perennial herbs,consecutive lack of emergence between seasons and years was frequent,which suggests a direct relationship with the mechanism of physical dormancy and the environmental conditions necessary to overcome integument *** these species,seed dimorphism and dormancy may confer additional advantages to their ***,presenting intermediate levels of physical dormancy in an annual species may be an evolutionary adjustment to rainfall *** contrast,we found that the annual herb without dormancy is more sensitive to seasonal and interannual climate changes,as evidenced by the increase and significant reduction of its emergence in the soil seed *** differences acquired evoluti

关键词： establishment herbaceous species physical dormancy seed bank seed germination semiarid

Psychopharmacological Profile of Hydroalcoholic Extract and P-Hydroxybenzoic Acid Obtained from <i>Bourreria huanita</i>(Boraginaceae) in Mice

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Pharmacology & Pharmacy 2014年第11期5卷 983-995页

作者： Iandra Holzmann Daiane Cattani Micheli Corso Daiane Perondi Sabrina Zanella Cristiani Burger Luiz Carlos Klein Júnior Valdir Cechinel Filho Sully M. Cruz Miguel F. Torres Armando Cáceres Márcia Maria de Souza Programa de Pós-Graduação em Ciências Farmacêuticas Universidade do Vale do Itajaí Itajaí Brazil Núcleo de Investigações Químico Farmacêuticas Universidade do Vale do Itajaí Itajaí Brazil Facultad de CCQQ y Farmacia Universidad de San Carlos Guatemala City Guatemala

Bourreria huanita (Lex.) Hemsl. (Boraginaceae) is a very rare and highly appreciated tree in Mesoamerica for its medicinal properties and beauty. It grows in a region extending from central Mexico to Costa Rica. Ethnobotanical surveys have shown that the infusion of dried flowers is popularly used as a tranquilizer to cure several diseases. In the present study we report the isolation of p-hydroxybenzoic acid (pHBZ) obtained from the hydroalcoholic extract (HE) of B. huanita, and the effect of both, the extract and the compound on the central nervous system in mice. HE of B. huanita (100, 150, 300 mg/kg) and pHBZ (10 mg/kg) were orally administered to mice and 1 h later, behavioral tests were performed. The effects of HE and pHBZ were tested by pentylenetetrazole (PTZ) and strychnine (STR) induced seizures, pentobarbital-induced hypnosis, the forced swimming test and the tail suspension test, the elevated plus maze, apomorphine-induced stereotypy and the climbing test, the inhibitory avoidance test and the open-field test. B. huanita extract produced hypnotic, anxiolytic and antidepressant effects in animals, with no change in motor performance. On the other hand, the extract did not reduce PTZ and STR-induced convulsions, apomorphine-induced stereotypy or climbing. Moreover, no changes were observed in the animals’ memory. The compound pHBZ was effective only in the depression tests. The results obtained in the present study suggest that B. huanita exhibited sedative, antidepressant and hypnotic activities in mice, and that the antidepressant activity may be mediated by an isolated compound identified as pHBZ.

关键词： Bourreria huanita Antidepressant Sedative and Hypnotic Activities P-Hydroxybenzoic Acid

Shade coffee plantations maintain woody plant diversity and structure in a cloud forest landscape of southern Mexico

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Journal of Forestry Research 2021年第2期32卷 637-648页

作者： Edson AAlvarez-Alvarez R.Carlos Almazán-Nunez Fernando González-García Marlene Brito-Millán Alfredo Méndez-Bahena Sergio García-Ibáñez Maestría en Recursos Naturales y Ecología Facultad de Ecología MarinaUniversidad Autónoma de Guerrero39390 AcapulcoGuerreroMexico Laboratorio Integral de Fauna Silvestre Facultad de Ciencias Químico-BiológicasUniversidad Autónoma de Guerrero39090 Chilpancingo de los BravoGuerreroMexico Red Biología y Conservación de Vertebrados Instituto de EcologíaA.C.CP 91073 XalapaVeracruzMexico University of California Institute for Mexico and the United States(UC MEXUS) Cuerpo Académico Biodiversidad y Gestión Ambiental SustentableFacultad de Ciencias Químico-BiológicasUniversidad Autónoma de Guerrero39090 Chilpancingo de los BravoGuerreroMexico Laboratorio de Biología de la Conservación Facultad de Ciencias Químico-BiológicasUniversidad Autónoma de Guerrero39090 Chilpancingo de los BravoGuerreroMexico Laboratorio de Ecología Cuantitativa Facultad de Ecología MarinaUniversidad Autónoma de Guerrero39390 AcapulcoGuerreroMexico

Cloud forest ecosystems of the Latin American tropics are highly threatened by changes in land-use such as expanding croplands and livestock pastures that promote shifts in the structure and composition of plant communities in these ***,shade coffee plantations represent a forest management alternative that has been shown to maintain biodiversity in these *** this study,we evaluated changes in the composition,diversity,and structure of Mexican cloud-forest woody species for three land use categories:cattle pastures,shade coffee plantations and advanced succession *** each category,fifteen 0.28-ha plots were established and the composition and diversity of vegetation was *** of species was analyzed using ordination methods,and alpha diversity was compared using Hill ***-seven woody species belonging to 40 families were *** richness and diversity was high in both the advanced successional forest and coffee plantations compared to cattle *** composition and structure was similar between late succession forests and coffee plantations with both land uses also being more structurally complex than cattle *** results show how shade coffee cultivation is a land-use activity that maintains woody plant communities in a manner that aligns with biodiversity conservation.

关键词： Land uses Late succession Plant diversity Shade coffee Vegetation structure

A new microchannel capillary flow assay (MCFA) platform with lyophilized chemiluminescence reagents for a smartphone-based POCT detecting malaria

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Microsystems & Nanoengineering 2020年第1期6卷 1316-1333页

作者： Sthitodhi Ghosh Kashish Aggarwal Vinitha T.U Thinh Nguyen Jungyoup Han Chong H.Ahn Department of Electrical Engineering and Computer Science Microsystems and BioMEMS LaboratoryUniversity of CincinnatiCincinnatiOH 45221USA mico BioMed USA Inc. 10999 Reed Hartman HighwaySTE 309CCincinnatiOH 45242USA

There has been a considerable development in microfluidic based immunodiagnostics over the past few years which has greatly favored the growth of novel point-of-care-testing(POCT).However,the realization of an inexpensive,low-power POCT needs cheap and disposable microfluidic devices that can perform autonomously with minimum user *** work,for the first time,reports the development of a new microchannel capillary flow assay(MCFA)platform that can perform chemiluminescence based ELISA with lyophilized chemiluminescent *** new MCFA platform exploits the ultra-high sensitivity of chemiluminescent detection while eliminating the shortcomings associated with liquid reagent handling,control of assay sequence and user *** functionally designed microchannels along with adequate hydrophilicity produce a sequential flow of assay reagents and autonomously performs the ultra-high sensitive chemiluminescence based ELISA for the detection of malaria biomarker such as *** MCFA platform with no external flow control and simple chemiluminescence detection can easily communicate with smartphone via USB-OTG port using a custom-designed optical *** use of the smartphone for display,data transfer,storage and analysis,as well as the source of power allows the development of a smartphone based POCT analyzer for disease *** paper reports a limit of detection(LOD)of 8 ng/mL by the smartphone analyzer which is sensitive enough to detect active malarial *** MCFA platform developed with the smartphone analyzer can be easily customized for different biomarkers,so a hand-held POCT for various infectious diseases can be envisaged with full networking capability at low cost.

关键词： POCT smart capillary