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Recovery after ischemic stroke:Effects of FuekFone home-based program on upper limb and cognitive function

international Journal of Nursing Sciences 2024年第4期11卷 414-420,I0001页

作者： Yaowalak Kumkwan Ketsarin Utriyaprasit Thitipong Tankumpuan Zeng Lertmanorat Boonyanit Mathayomchan Faculty of Nursing Mahidol UniversityNakhon PathomThailand Engineering Faculty of Engineering Mahidol UniversityNakhon PathomThailand international College Mahidol UniversityNakhon PathomThailand

Objectives:This study aimed to explore the effects of the“FuekFone(F.F.)home-based program”on the upper limb and cognitive function of ischemic stroke patients after ***:A single group pre-and post-test design was conducted.A total of 40 patients with recovery after ischemic stroke were recruited from two university hospitals in *** study was conducted between June 2022 and January *** underwent a six-week“***-based program,”which combined an upper limb and cognitive function rehabilitation device with Android games,including stationary barrel,adventure walk,adventure stroll,sliding barrel,sauce squeeze,and cut *** game has different difﬁculty *** can perform corresponding exercises through the games according to their conditions under the guidance of medical *** patients played for 24 min per time,4 min each game,three days a *** second week,let the patients play games for 30 min per time,5 min each game,3 days a ***,in the 3e6 weeks,let the patients play games for 1 h per time,10 min each game,5 days a *** the pre-and post-intervention,the Thai version of the National Institutes of Health Stroke Scale(NIHSS),the Motor Assessment Scale,and the Montreal Cognitive Assessment(MoCA score)were administered to patients at discharge and at 2,4,and 6 weeksafter discharge,and the results were ***:All participants completed this *** had statistically improved upper limb function(upper arm function score,hand movements score,advanced hand activities score,total Motor Assessment Scale score)and MoCA score at 2,4,and 6 weeks after discharge(Pstudy times,we found statistically improved upper limb function(upper arm function score,hand movements score,advanced hand activities score,total Motor Assessment Scale score)and MoCA score at 4,and 6 weeks after discharge when compared to af

关键词： Application program Cognitive Home-based program Ischemic stroke Patients Upper extremity

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Optimization design and experiment of the variable differential gear train planting mechanism

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international Journal of Agricultural and Biological Engineering 2024年第2期17卷 85-93页

作者： Xiong Zhao Ziwei Liu Yuanwu Jia Xingxiao Ma Pengfei Zhang Jianneng Chen School of Mechanical Engineering Zhejiang Sci-Tech UniversityHangzhou 310018China Xi’an international University Engineering College Xi’an 710077China Hangzhou Vocational&Technical College Hangzhou 310018China

In order to improve the adaptability of the planting mechanism for different plant spacings,a variable differential gear train planting mechanism based on precise pose and trajectory control was proposed by combining the open chain 2R rod group and the variable differential gear *** to the pose requirements of receiving seedling point,transporting seedling point and planting point,three precise pose points of constrained planting trajectory were *** the three-position motion generation structural synthesis method,combined with computer-aided optimization design software,a set of mechanism parameters that meet the planting requirements were *** on the optimized mechanism parameters,by only changing the coordinates of two trajectory shape control points,three planting trajectories with key point position information adapted to 300 mm,400 mm and 500 mm plant spacing were obtained by interpolation,and three pairs of total transmission ratio of three groups of variable differential gear trains were *** distributing the total transmission ratio of the mechanism,the fixed axis gear train and the differential gear train are *** fixed axis gear train included a pair of non-circular gear pairs and a pair of positive gear pairs,which were convenient for disassembly and *** former drives the sun gear at variable speed,and the latter drives the planet carrier at uniform *** on this structure,the transmission ratio of the positive gear pair is-1,and the transmission ratio of the differential gear train is *** sub-transmission ratio of the single-stage non-circular gear pair was calculated and the pitch curves of three pairs of noncircular gears were *** pairs of non-circular gear pairs with different transmission ratios were replaced in turn and three sets of planting mechanisms were modeled in three *** virtual prototype motion simulation was completed by ADAMS software,and the p

关键词： plant spacing planting mechanism variable differential gear train precise pose trajectory control parameter optimization

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Understanding the Historical Significance and Contemporary Value of the Distinctive Features of Chinese Civilisation

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international Understanding 2024年第2期 8-17页

作者：无 CPC Leading group of the Chinese Academy of Social Sciences

At a meeting on cultural inheritance and development held in Beijing,June 2,2023,President Xi Jinping put forward a holistic and systematic explanation of the distinctive features of Chinese civilisation-consistency,originality,unity,inclusiveness,and a peaceful *** by the scientific methodology of dialectical and historical materialism and an overarching strategic perspective on the great undertakings of socialism with Chinese characteristics in the new era,President Xi Jinping's profound exposition has granted us a deeper understanding of the laws underlying the development of Chinese civilisation by shedding light on its intrinsic *** understanding bears not just immense historical importance but also significant contemporary value.

关键词： peace historical civil

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Computer-controlled ultra high voltage amplifier for dielectric elastomer actuators

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Biomimetic Intelligence & Robotics 2024年第1期4卷 14-23页

作者： Ardi Wiranata Zebing Mao Yu Kuwajima Yuya Yamaguchi Muhammad Akhsin Muflikhun Hiroki Shigemune Naoki Hosoya Shingo Maeda Department of Mechanical and Industrial Engineering University of Gadjah MadaYogyakarta 55281Indonesia Department of Mechanical Engineering Tokyo Institute of TechnologyTokyo 152-8550Japan Department of Engineering and Science Shibaura Institute of TechnologyTokyo 135-8548Japan Department of Electrical Engineering Shibaura Institute of TechnologyTokyo 135-8548Japan Department of Engineering Science and Mechanics Shibaura Institute of TechnologyTokyo 135-8548Japan Living Systems Materialogy(LiSM)Research group International Research Frontiers Initiative(IRFI)Tokyo Institute of TechnologyYokohama 226-8501Japan

Soft robotics is a breakthrough technology to support human-robot *** soft structure of a soft robot can increase safety during human and robot *** of the promising soft actuators for soft robotics is dielectric elastomer actuators(DEAs).DEAs can operate silently and have an excellent energy *** simple structure of DEAs leads to the easy fabrication of soft *** simplicity combined with silent operation and high energy density make DEAs interesting for soft robotics *** actuation follows the Maxwell-pressure *** pressure produced in the DEAs actuation depends much on the voltage *** DEAs requires high voltage to gain an *** the power consumption of DEAs is in the milli-Watt range,the current needed to operate the DEAs can be *** commercially available DC-DC converters can convert the volt range to the kV *** order to get a voltage in the 2-3 kV range,the reliable DC-DC converter can be pricy for each *** problem hinders the education of soft actuators,especially for a newcomer laboratory that works in soft electric *** paper introduces an entirely do-it-yourself(DIY)Ultrahigh voltage amplifier(UHV-Amp)for education in soft ***-Amp can amplify 12 V to at a maximum of 4 kV *** a demonstration,we used this UHV-Amp to test a single layer of powdered-based *** strategy to build this educational type UHV-Amp was utilizing a Cockcroft-Walton circuit structure to amplify the voltage range to the kV *** its current state,the UHV-Amp has the potential to achieve approximately 4 *** created a simple platform to control the UHV-Amp from a personal *** near future,we expect this easy control of the UHV-Amp can contribute to the education of soft electric actuators.

关键词： Dielectric elastomer actuators Electric amplifier Soft actuators Soft robotics Soft actuator education

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Brain protective effect of dexmedetomidine vs propofol for sedation during prolonged mechanical ventilation in non-brain injured patients

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World Journal of Psychiatry 2024年第3期14卷 370-379页

作者： Hong-Xun Yuan Li-Na Zhang Gang Li Li Qiao Intensive Care Unit Peking University International HospitalBeijing 102206China Central Operating Room The Affiliated Beijing Chaoyang Hospital of Capital Medical UniversityBeijing 100020China

BACKGROUND Dexmedetomidine and propofol are two sedatives used for long-term *** remains unclear whether dexmedetomidine provides superior cerebral protection for patients undergoing long-term mechanical *** To compare the neuroprotective effects of dexmedetomidine and propofol for sedation during prolonged mechanical ventilation in patients without brain *** Patients who underwent mechanical ventilation for>72 h were randomly assigned to receive sedation with dexmedetomidine or *** Richmond Agitation and Sedation Scale(RASS)was used to evaluate sedation effects,with a target range of-3 to *** primary outcomes were serum levels of S100-βand neuron-specific enolase(NSE)every 24 *** secondary outcomes were remifentanil dosage,the proportion of patients requiring rescue sedation,and the time and frequency of RASS scores within the target *** A total of 52 and 63 patients were allocated to the dexmedetomidine group and propofol group,*** data were comparable between *** significant differences were identified between groups within the median duration of study drug infusion[52.0(IQR:36.0-73.5)h vs 53.0(IQR:37.0-72.0)h,P=0.958],the median dose of remifentanil[4.5(IQR:4.0-5.0)μg/kg/h vs 4.6(IQR:4.0-5.0)μg/kg/h,P=0.395],the median percentage of time in the target RASS range without rescue sedation[85.6%(IQR:65.8%-96.6%)vs 86.7%(IQR:72.3%-95.3),P=0.592],and the median frequency within the target RASS range without rescue sedation[72.2%(60.8%-91.7%)vs 73.3%(60.0%-100.0%),P=0.880].The proportion of patients in the dexmedetomidine group who required rescue sedation was higher than in the propofol group with statistical significance(69.2%vs 50.8%,P=0.045).Serum S100-βand NSE levels in the propofol group were higher than in the dexmedetomidine group with statistical significance during the first six and five days of mechanical ventilation,respectively(all P<0.05).CONCLUSION Dexmedetomidine demonstrated

关键词： Dexmedetomidine Propofol Sedation Prolonged mechanical ventilation Brain protective

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Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex promotes intestinal development as a new iron supplement

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Science China Life Sciences 2024年

作者： Yingying Feng Yuying Wu Jialu Wang Zhenglin Dong Qian Yu Shuangshuang Xia Chunxue Liu Haihua Wang Xin Wu Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences CAS Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical Agriculture Chinese Academy of Sciences ANYOU Biotechnology group Co.Ltd Qingdao Seawin Biotech group Co. Ltd

Iron is a crucial micronutrient, and its deficiency can have detrimental effects on the health of infants. Dietary polysaccharide-iron(Ⅲ) complexes(PICs) are promising for addressing iron deficiency due to their minimal adverse reactions and high iron absorption rate. This study aimed to investigate the effects of dietary Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex(EP-Fe) on newborns, using 3-day weaned piglets as the iron-deficiency model. Results showed that EP-Fe improved iron levels and promoted intestinal development in piglets. Transcriptome sequencing revealed that EP-Fe increased the survival of intestinal epithelial cells under hypoxia by upregulating the expression of genes that promote the development of the vascular system. Additionally, EP-Fe enhanced the mucosal barrier functions by inhibiting myosin light chain kinase(MLCK)/phosphorylated myosin light chain(p-MLC)signaling pathway to increase the expression of intestinal tight junction proteins. Furthermore, the 16S rRNA gene sequencing of gut microbiota showed that EP-Fe promoted the enrichment of Bacteroides＿fragilis and other gut microbes that can metabolize carbohydrates. In conclusion, EP-Fe is an effective iron supplement for newborns, and it can be developed as a comprehensive nutritional supplement.

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Dynamical Modeling and Dynamic Characteristics Analysisof a Coaxial Dual-Rotor System

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Journal of Dynamics, Monitoring and Diagnostics 2024年第2期3卷 99-111页

作者： Yubin Yue Hongjun Wang Shenglun Zhang China Academy of Machinery Science and Technology group Co. Ltd.BeijingChina School of Mechanical and Electrical Engineering Beijing Information Science and Technology UniversityBeijingChina Key Laboratory of Modern Measurement and Control Technology Ministry of EducationBeijing Information Science and Technology UniversityBeijingChina Beijing international Science and Technology Cooperation Base of High-end Equipment Intelligent Perception and Control Beijing Information Science and Technology UniversityBeijingChina

The dual-rotor structure serves as the primary source of vibration in aero-engines. Understanding itsdynamical model and analyzing dynamic characteristics, such as critical speed and unbalanced response, arecrucial for rotor system dynamics. Previous work introduced a coaxial dual-rotor-support scheme for aeroengines,and a physical model featuring a high-speed flexible inner rotor with a substantial length-to-diameter ratiowas designed. Then a finite element (FE) dynamic model based on the Timoshenko beam elements and rigid bodykinematics of the dual-rotor system is modeled, with the Newmark method and Newton–Raphson method used forthe numerical calculation to study the dynamic characteristics of the system. Three different simulation models,including beam-based FE (1D) model, solid-based FE (3D) model, and transfer matrix model, were designed tostudy the characteristics of mode and the critical speed characteristic of the dual-rotor system. The unbalancedresponse of the dual-rotor system was analyzed to study the influence of mass unbalance on the rotor system. Theeffect of different disk unbalance phases and different speed ratios on the dynamic characteristics of the dual-rotorsystem was investigated in detail. The experimental result shows that the beam-based FE model is effective andsuitable for studying the dual-rotor system.

关键词： coaxial dual-rotor system dynamical modeling dynamic characteristics analysis rotor dynamics

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Dynamic changes of rumen microbiota and serum metabolome revealed increases in meat quality and growth performances of sheep fed bio‑fermented rice straw

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1207-1226页

作者： Yin Yin Kyawt Min Aung Yao Xu Zhanying Sun Yaqi Zhou Weiyun Zhu Varijakshapanicker Padmakumar Zhankun Tan Yanfen Cheng Laboratory of Gastrointestinal Microbiology National Center for International Research on Animal Gut NutritionNanjing Agricultural UniversityNanjing 210095China Department of Animal Nutrition University of Veterinary ScienceNay Pyi Taw 15013Myanmar international Livestock Research Institute Nairobi 00100Kenya College of Animal Science Tibet Academy of Agricultural and Animal Husbandry SciencesLhasa 850000China State Key Laboratory of Grassland Agro‑Ecosystems Center for Grassland MicrobiomeCollege of Pastoral Agriculture Science and TechnologyLanzhou UniversityLanzhou 730000China

Background Providing high-quality roughage is crucial for improvement of ruminant production because it is an essential component of their *** previous study showed that feeding bio-fermented rice straw(BF)improved the feed intake and weight gain of ***,it remains unclear why feeding BF to sheep increased their feed intake and weight ***,the purposes of this research were to investigate how the rumen micro-biota and serum metabolome are dynamically changing after feeding BF,as well as how their changes influence the feed intake,digestibility,nutrient transport,meat quality and growth performances of *** growing Hu sheep were allocated into 3 groups:alfalfa hay fed group(AH:positive control),rice straw fed group(RS:negative control)and BF fed group(BF:treatment).Samples of rumen content,blood,rumen epithelium,muscle,feed offered and refusals were collected for the subsequent *** Feeding BF changed the microbial community and rumen fermentation,particularly increasing(P<0.05)relative abundance of Prevotella and propionate production,and decreasing(P<0.05)enteric methane *** histomorphology(height,width,area and thickness)of rumen papillae and gene expression for carbohydrate trans-port(MCT1),tight junction(claudin-1,claudin-4),and cell proliferation(CDK4,Cyclin A2,Cyclin E1)were improved(P<0.05)in sheep fed ***,serum metabolome was also dynamically changed,which led to up-regulating(P<0.05)the primary bile acid biosynthesis and biosynthesis of unsaturated fatty acid in sheep fed *** a result,the higher(P<0.05)feed intake,digestibility,growth rate,feed efficiency,meat quality and mono-unsaturated fatty acid concentration in muscle,and the lower(P<0.05)feed cost per kg of live weight were achieved by feeding *** Feeding BF improved the growth performances and meat quality of sheep and reduced their feed ***,bio-fermentation of rice straw could be an innovative way for improving rum

关键词： Bio-fermentation Growth rate Meat quality Metabolome Microbiota Rice straw

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Unleashing the Power of Multi-Agent Reinforcement Learning for Algorithmic Trading in the Digital Financial Frontier and Enterprise Information Systems

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Computers, Materials & Continua 2024年第8期80卷 3123-3138页

作者： Saket Sarin Sunil K.Singh Sudhakar Kumar Shivam Goyal Brij Bhooshan Gupta Wadee Alhalabi Varsha Arya Chandigarh College of Engineering and Technology Chandigarh160019India Department of Computer Science and Information Engineering Asia UniversityTaichung413Taiwan Symbiosis Centre for Information Technology(SCIT) Symbiosis International UniversityPune411057India Center for Interdisciplinary Research University of Petroleum and Energy Studies(UPES)Dehradun248007India Department of Computer Science Immersive Virtual Reality Research GroupKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Business Administration Asia UniversityTaichung413Taiwan Department of Electrical and Computer Engineering Lebanese American UniversityBeirut11022801Lebanon UCRD Chandigarh UniversityChandigarh140413India

In the rapidly evolving landscape of today’s digital economy,Financial Technology(Fintech)emerges as a trans-formative force,propelled by the dynamic synergy between Artificial Intelligence(AI)and Algorithmic *** in-depth investigation delves into the intricacies of merging Multi-Agent Reinforcement Learning(MARL)and Explainable AI(XAI)within Fintech,aiming to refine Algorithmic Trading *** meticulous examination,we uncover the nuanced interactions of AI-driven agents as they collaborate and compete within the financial realm,employing sophisticated deep learning techniques to enhance the clarity and adaptability of trading *** AI-infused Fintech platforms harness collective intelligence to unearth trends,mitigate risks,and provide tailored financial guidance,fostering benefits for individuals and enterprises navigating the digital *** research holds the potential to revolutionize finance,opening doors to fresh avenues for investment and asset management in the digital ***,our statistical evaluation yields encouraging results,with metrics such as Accuracy=0.85,Precision=0.88,and F1 Score=0.86,reaffirming the efficacy of our approach within Fintech and emphasizing its reliability and innovative prowess.

关键词： Neurodynamic Fintech multi-agent reinforcement learning algorithmic trading digital financial frontier

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Developing Skills in Intra-Workplace Rehabilitation Education: Paper III

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Open Journal of Therapy and Rehabilitation 2024年第1期12卷 70-100页

作者： Fukumi Hiragami Research Institute of Health and Welfare Kibi International University Takahashi Japan

Rehabilitation is a medical discipline which is needed wherever people have lost full functionality, and it is needed increasingly in noncommunicable diseases, such as neurological problems, but also, and perhaps more importantly, in middle- and high-income countries, where populations are growing more aged. The burden is borne by the health care systems, especially where family cannot take the full load of care. Rehabilitation is also a discipline which is carried out most effectively in multi- or interdisciplinary teams, which carry their own weight of learning and group tensions. They are also bound to consider best practice guidelines. Furthermore, there is also a wide gap between learning in college or university and practice in the ward which leads to a loss of confidence in newly trained medical and paramedical personnel such as doctors, nurses, physiatrists, occupational therapists and physiotherapists. There is a genuine need for expert rehabilitation specialists who can mediate within teams as well as between groups and patients and their families. This paper lays out the range of considerations such a rehabilitation therapist must have under their belt. A model is presented. There are also two sets of parameters when using the model in practice. The first is the levels at which it works: hospital, departmental and individual. Then there are the specific challenges. Curriculum practice guidelines work at the hospital and departmental and professional levels;teamwork with its intrinsic challenges is of paramount importance;finally, the individuals will learn how to represent their insights in writing, most specifically represented in full-blown case reports. If the levels and roles coordinate, rehabilitation medicine should develop favourably.

关键词： Rehabilitation Clinical Practice Teamwork Case Studies Writing up Case Reports

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