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Molecular regulation of the key specialized metabolism pathways in medicinal plants

Journal of Integrative Plant Biology 2024年第3期66卷 510-531页

作者： Min shi siwei Zhang Zizhen Zheng Itay Maoz Lei Zhang Guoyin Kai zhejiang provincial international s&t cooperation base for active ingredients of medicinal and edible plants and health Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and TransformationSchool of Pharmaceutical SciencesJinhua AcademyZhejiang Chinese Medical UniversityHangzhou 310053China Department of Postharvest science Agricultural Research OrganizationVolcani CenterRishonLeZion 7505101Israel Department of Pharmaceutical Botany School of PharmacyNaval Medical UniversityShanghai 200433China

the basis of modern pharmacology is the human ability to exploit the production of specialized metabolites from medical plants,for example,terpenoids,alkaloids,and phenolic ***,in most cases,the availability of these valuable compounds is limited by cellular or organelle barriers or spatio-temporal accumulation patterns within different plant *** factors(tFs)regulate biosynthesis of these specialized metabolites by tightly controlling the expression of biosynthetic ***-edge technologies and/or combining multiple strategies and approaches have been applied to elucidate the role of *** this review,we focus on recent progress in the transcription regulation mechanism of representative high-value products and describe the transcriptional regulatory network,and future perspectives are discussed,which will help develop high-yield plant resources.

关键词： biosynthesis medicinal plants omics secondary metabolism transcription factors

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Recent Advances in Nano‑Enabled seed treatment strategies for sustainable Agriculture:Challenges,Risk Assessment,and Future Perspectives

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Nano-Micro Letters 2023年第4期15卷 153-189页

作者： Amruta shelar shivraj Hariram Nile Ajay Vikram singh Dirk Rothenstein Joachim Bill Jianbo Xiao Manohar Chaskar Guoyin Kai Rajendra Patil Department of technology Savitribai Phule Pune UniversityPuneMaharashtra 411007India zhejiang provincial international s&t cooperation base for active ingredients of medicinal and edible plants and health School of Pharmaceutical ScienceJinhua AcademyZhejiang Chinese Medical UniversityHangzhou 310053ZhejiangPeople’s Republic of China Department of Chemical and Product safety German Federal Institute for Risk Assessment(BfR)Max‑Dohrn‑Strasse10589 BerlinGermany Institute for Materials science University of Stuttgart70569 StuttgartGermany international Research Center for Food Nutrition and safety Jiangsu UniversityZhenjiang 212013People’s Republic of China Faculty of science and technology Savitribai Phule Pune UniversityPuneMaharashtra 411007India Department of Biotechnology Savitribai Phule Pune UniversityPuneMaharashtra 411007India

Agro seeds are vulnerable to environmental stressors,adversely affecting seed vigor,crop growth,and crop *** agrochemical-based seed treatments enhance seed germination,but they can also cause damage to the environment;therefore,sustainable technologies such as nano-based agrochemicals are urgently *** can reduce the dose-dependent toxicity of seed treatment,thereby improving seed viability and ensuring the controlled release of nanoagrochemical active ingredients However,the applications of nanoagrochemicals to plants in the field raise concerns about nanomaterial safety,exposure levels,and toxicological implications to the environment and human *** the present comprehensive review,the development,scope,challenges,and risk assessments of nanoagrochemicals on seed treatment are ***,the implementation obstacles for nanoagrochemicals use in seed treatments,their commercialization potential,and the need for policy regulations to assess possible risks are also *** on our knowledge,this is the first time that we have presented legendary literature to readers in order to help them gain a deeper understanding of upcoming nanotechnologies that may enable the development of future generation seed treatment agrochemical formulations,their scope,and potential risks associated with seed treatment.

关键词： Agro seeds Environmental seed stressors Nanoagrochemicals toxicological implications Risk regulations

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