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Attempted Removal of Oxygen Function at 1-Position of 10-Deacetylbaccatin Ⅲ

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Chinese Chemical Letters 1998年第4期9卷 373-375页

作者： Da Li YIN yoshinori SEKIGUCHI Kazuya KAMEO(Institute of Materia Medica, Chinese Academy of Med. Sci. & Peking Union Med. College, Bejing 100050 (Taisho Pharmaceutical Co. Ltd. 403 yoshino-cho 1-chome Ohmiya-shi, Saitama, 330, Japan) Institute of Materia Medica Chinese Academy of Med. Sci. Peking Union Med. College Beijing 100050 China Taisho Pharmaceutical Co. Ltd. Ohmiya-shi Saitama 330 403 Yoshino-Cho 1-Chome Japan

1-Hydroxyl acetylation of 10-deacetylbaccatin Ⅲ was achieved by removing the neighboring bulky 2-benzoyl group and oxidizing 2-hydroxyl group to a ketone function, but attempted reductive cleavage of 1-acetoxy gave r... 详细信息

关键词： taxoids baccatin Ⅲ SmI_2 reduction

Spinal cord injury regenerative therapy development:integration of design of experiments

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Neural Regeneration Research 2025年第9期20卷 2571-2573页

作者： Yuji Okano Hideyuki Okano Yoshitaka Kase Division of CNS Regeneration and Drug Discovery International Center for Brain Science(ICBS)Fujita Health UniversityKutsukake-ChoToyoake-ShiAichiJapan Department of Extended Intelligence for Medicine The Ishii-Ishibashi LaboratoryKeio University School of MedicineShinanomachiShinjuku-KuTokyoJapan Keio University Regenerative Medicine Research Center Kawasaki-kuKawasaki-shiJapan

Spinal cord injury(SCI)can cause motor and sensory paralysis,and autonomic nervous system disorders including malfunction of urination and defecation,thereby significantly impairing the quality of *** continue to explo re new stem cell strategies for the treatment of paralysis by transpla nting human induced pluripotent stem cell-derived neural ste m/progenitor cells(hiPSCNS/PCs)into spinal cord injured tissues.

关键词： Spinal paralysis injury

Formation of ST Plasmas by ECH on LATE

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Plasma Science and Technology 2004年第4期6卷 2364-2366页

作者： M.Uchida T.Maekawa H.Tanaka H.Igami T.Yoshinaga K.Katsuura M.Konno Kyoto University Kita shirakawa Oiwake-choKyoto 606-8502JapanKyoto UniversityKita shirakawa Oiwake-choKyoto 606-8502JapanKyoto UniversityKita shirakawa Oiwake-choKyoto 606-8502JapanKyoto UniversityKita shirakawa Oiwake-choKyoto 606-8502JapanKyoto UniversityKita shirakawa Oiwake-choKyoto 606-8502JapanKyoto UniversityKita shirakawa Oiwake-choKyoto 606-8502JapanKyoto UniversityKita shirakawa Oiwake-choKyoto 606-8502Japan

Experiments on formation of spherical tokamak (ST) plasmas by electroncyclotron heating (ECH) alone without a central OH solenoid have been carried out on LATE (LowAspect ratio Torus Experiments). By injecting a 2.45 GHz microwave pulse of 6.3 kW for 4 seconds, aplasma current is initiated and ramped up to I_p approx= 3 kA, and finally maintained for 1 secondby adjusting the external vertical field. Magnetic measurements show that closed flux surfaces areformed and the last closed flux surface has an aspect ratio of A ～ 1.3 and an elongation of κ～1.3. The electron density measured by an interferometer is more than 1.5 x 10^(11) cm^(-3) whichexceeds twice of the plasma cut-off density, suggesting that electron cyclotron heating bymode-converted electron Bernstein waves may take place.

关键词： spherical tokamak non-inductive start-up electron cyclotron heating

On the Plasma (ion) Carburized Layer of High Nitrogen Austenitic Stainless Steel

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材料热处理学报 2004年第5期25卷 375-377页

作者： Y. Ueda N. Kanayama K. Ichii T. Oishi H. Miyake Shimane Institute for Industrial Technology 1 Hokuryo-cho Matsue Shimane 690-0816 JapanShimane Institute for Industrial Technology 1 Hokuryo-cho Matsue Shimane 690-0816 JapanFaculty of Engineering Kansai University 3-3-35 Yamate-cho Suita Osaka 564-8680 JapanFaculty of Engineering Kansai University 3-3-35 Yamate-cho Suita Osaka 564-8680 JapanFaculty of Engineering Kansai University 3-3-35 Yamate-cho Suita Osaka 564-8680 Japan

The manganese concentration of austenitic stainless steel decreases from the inner layer towards the surface of the plasma (ion) carburized layer due to the evaporation of manganese from the specimen surface. The carbon concentration in the carburized layer is influenced by alloyed elements such as Cr, Ni, Si, and Mo, as well as Nitrogen. This study examined the effects of nitrogen on the properties of the carburized layer of high nitrogen stainless steel. Plasma (ion) carburizing was carried out for 14.4 ks at 1303 K in an atmosphere of CH4+H2 gas mixtures under a pressure of 350 Pa. The plasma carburized layer of the high nitrogen stainless steel was thinner than that of an austentric stainless steel containing no nitrogen. This suggested that the nitrogen raised the activity of carbon in the plasma carburized layer, GDOES measurement indicated that the nitrogen level in the layer did not vary after plasma (ion) carburizing.

关键词：等离子渗碳高氮不锈钢奥氏体 GDOES

Evaluation of Important Factors Affecting Quench Distortion of Carburized Hypoid Gear with Shaft by Using Computer Simulation Methods

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材料热处理学报 2004年第5期25卷 480-485页

作者： Tsuyoshi Sugimoto Youichi Watanabe Nissan Motor Co. Ltd. 6-1 Daikoku-cho Tsurumi Yokohama JapanNissan Motor Co. Ltd. 6-1 Daikoku-cho Tsurumi Yokohama Japan

To minimize quenching distortion and dispersion, carburizing and quenching process conditions must be optimized; this includes the parts racking design used for quenching. We investigated some factors affecting carburized quenching distortion with an experiment using a hypoid gear having a shaft and with numerical simulation methods. The experimental results and those obtained from simulation were generally in agreement. Focusing on the surface temperature distribution in the gear, we studied quenching distortion characteristics in terms of changes in tooth profile and helix deviation. In our experiments, distortions occur during quenching in 373 K oil after austenitized temperature treatments conducted with various attitudes. We calculated the distortions by simulating the carburized oil-quenching process for the hypoid gear. Our results show large differences between the cooling rates of the tooth toe, middle section, and heel edges, and these greatly influence the change in tooth profile and helix deviation. We found that reducing the differences in temperatures on the gear surfaces during quenching is most important for minimizing the quench distortion of the hypoid gear.

关键词：淬火变形螺旋偏差外形偏差冷却曲线传热系数准双曲面齿轮

Analysis of Aerodynamic Load on Straight-bladed Vertical Axis Wind Turbine

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Journal of Thermal Science 2014年第4期23卷 315-324页

作者： Qing’an LI Takao MAEDA Yasunari KAMADA Junsuke MURATA Toshiaki KAWABATA Kazuma FURUKAWA Division of System Engineering Mie University1577 Kurimamachiya-choTsuMie 514-8507JAPAN Division of Mechanical Engineering Mie University1577 Kurimamachiya-choTsuMie 514-8507JAPAN

This paper presents a wind tunnel experiment for the evaluation of energy performance and aerodynamic forces acting on a small straight-bladed vertical axis wind turbine(VAWT) depending on several values of tip speed ratio. In the present study, the wind turbine is a four-bladed VAWT. The test airfoil of blade is symmetry airfoil(NACA0021) with 32 pressure ports used for the pressure measurements on blade surface. Based on the pressure distributions which are acted on the surface of rotor blade measured during rotation by multiport pressure-scanner mounted on a hub, the power, tangential force, lift and drag coefficients which are obtained by pressure distribution are discussed as a function of azimuthally position. And then, the loads which are applied to the entire wind turbine are compared with the experiment data of pressure distribution. As a result, it is clarified that aerodynamic forces take maximum value when the blade is moving to upstream side, and become small and smooth at downstream side. The power and torque coefficients which are based on the pressure distribution are larger than that by torque meter.

关键词： Wind Turbine Wind Energy Straight-bladed VAWT Tip Speed Ratio Pressure Distribution

Estimate of the Deposition Profile of Carbon Pellets Using a High-Speed VUV Imaging System in the LHD

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Plasma Science and Technology 2013年第12期15卷 1178-1183页

作者：明廷凤 Satoshi OHDACHI Yasuhiro SUZUKI LHD Experiment Group The Graduate University for Advanced Studies 322-60roshi-cho Toki 509-5292 Japan National Institute for Fusion Science 322-60roshi-cho Toki 509-5292 Japan

The deposition profile of the impurity pellet is measured by a two-dimensional fast- framing vacuum ultraviolet （VUV） camera system in the large helical device （LHD）. The fast framing camera selectively measures the emission from the hydrogen-like ions of carbon （C VI） with a frame rate of several kHz. From the emission profile of the hydrogen-like carbon ions, which are in the process of ionization, the initial deposition profile of the carbon is estimated using a simple one-dimensional transport model.

关键词： VUV impurity transport carbon pellet injection LHD

Performance and Internal Flow of Sirocco Fan Using Contra-Rotating Rotors

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Journal of Thermal Science 2008年第1期17卷 35-41页

作者： J.Fukutomi T.Shigemitsu T.Yasunobu Institute of Science and Technology The University of Tokushima2-1 Minamijyosanjima-choTokushima 770-8506JAPAN Institute of Science and Technology The University of Tokushima2-1 Minamijyosanjima-choTokushima 770-8506JAPAN Research Associate Graduate School of Advanced Technology and Science The University of Tokushima2-1 Minamijyosanjima-choTokushima 770-8506JAPAN

A sirocco fan using contra-rotating rotors in which an inner rotor is settled inside the sirocco fan rotor and each rotor rotates in an opposite direction was proposed for the purpose of getting the higher pressure and making the structure of a sirocco fan more compact. If the high discharge pressure is obtained with the adoption of the contra-rotating rotors, it could be used for various purposes. Pressure coefficient of a sirocco fan with contra-rotating rotors is 2.5 times as high as the conventional sirocco fan and the maximum efficiency point of contra-rotating rotors shifts to larger flow rate than a conventional sirocco fan. On the other hand, it was clarified from the flow measurement results that circumferential velocity component at the outlet of the outer rotor of contra-rotating ro- tors becomes larger than a conventional one. In the present paper, the performance of a conventional sirocco fan and a sirocco fan with contra-rotating rotors are shown and the internal flow field at the outlet of outer rotor of both cases is clarified. Then, the effect of different kind of contra-rotating rotors on the performance and internal flow field is investigated and the rotor design with higher performance would be discussed.

关键词： Sirocco fan High pressure Contra-rotating rotors Slow angle Circular arc blade Aerofoil blade

Performance Analysis of Mini Centrifugal Pump with Splitter Blades

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Journal of Thermal Science 2013年第6期22卷 573-579页

作者： T. Shigemitsu J. Fukutomi T. Wada H. Shinohara Institute of Technology and Science The University of Tokushima 2-1 Minamijosanjima-cho Tokushima 770-8506Japan Graduate School of Advanced Technology and Science The University of Tokushima 2-1 Minamijosanjima-choTokushima 770-8506 Japan

Design method for a mini centrifugal pump is not established because the internal flow condition for these small-sized fluid machines is not clarified and conventional theory is not suitable for small-sized pumps. Then, a semi-open impeller for the mini centrifugal pump with 55mm impeller diameter is adopted in this research to take simplicity and maintenance into consideration. Splitter blades are adopted in this research to improve the performance and internal flow condition of mini centrifugal pump having large blade outlet angle. The performance tests are conducted with these rotors in order to investigate the effect of the splitter blades on the performance and internal flow condition of the mini centrifugal pump. A three dimensional steady numerical flow analysis is conducted to analyze rotor, volute efficiency and loss caused by a vortex. It is clarified from the experimental results that the performance of the mini centrifugal pump is improved by the effect of the splitter blades. Flow condition at outlet of the rotor becomes uniform and back flow regions are suppressed in the case with the splitter ***, the volute efficiency increases and the vortex loss decreases. In the present paper, the performance of the mini centrifugal pump is shown and the flow condition is clarified with the results of the experiment and the numerical flow analysis. Furthermore, the performance analyses of the mini centrifugal pumps with and without the splitter blades are conducted.

关键词： Centrifugal pump Performance Internal flow Splitter blade