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Tourism Marketing Strategies for Satellite City against the Background of New Urbanization

Journal of Landscape Research 2016年第1期8卷 83-85,88页

作者： GAN Chang XIAO Hui ZENG Bo CHEN Lijun College of Tourism Culture and Geosciences Huanggang Normal University

Considering the development features of new urbanization, and tourism development conditions of xinzhou District, Wuhan City, this paper explored the inner integrated point of new urbanization and tourism industry, and on this basis proposed strategies for tourism marketing of satellite city by innovating traditional marketing, and applying new marketing methods, so as to build a high-efficiency, high-coverage marketing network, to promote the development of urban tourism, the integration of industries, and economic strength of satellite city, and to push forward the further implementation of new urbanization.

关键词： New urbanization Satellite city Tourism marketing xinzhou District

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Najaatra venom peptide selectively blocks voltage-gated sodium channel Nav1.8 to abolish pain

Najaatra venom peptide selectively blocks voltage-gated sodi...

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第12届生物毒素研究及医药应用学术大会

作者： Fan Zhang Dongfan Tang Heng Zhang xinzhou Wu Zhonghua Liu Songping Liang College of Life Sciences Hunan Normal University

The tetrodotoxin-resistant voltage-gated sodium channel(VGSC) Nav1.8 is expressed predominantly in small nociceptive primary afferent nerves and contributes to inflammatory and neuropathic *** we described the discovery of μ-EPTX-Na1 a,a unique 62-residue peptide from Najaatra venom,that potently blocked Nav1.8(IC50 of 167 nM) in rat dorsal root ganglion neurons,whereas micromolar concentration of u-EPTX-Nala showed no inhibition on Navl.9 and tetrodotoxin-sensitive VGSC currents in these *** the five VGSC subtypes(Nav1.3-1.5,Nav1.7 and Nav1.8) expressed heterologously,human Nav1.8 was the most sensitive to μ-EPTX-Na1(IC50 of 386 nM) with the selectivity at least 20-folds over other VGSC *** neuropathic and chronic inflammatory pain models,μ-EPTX-Nala displayed analgesic effect,even more potent than morphine in rodent models of acid-induced pain,formalin-induced secondary mechanical allodynia and intraplantar complete Freund’s adjuvant injection-induced pain,and similar to morphine in rodent models of thermal pain and partial nerve ligation-induced *** antinociceptive effect of this peptide was not associated with obvious side *** study establishes μ-EPTX-Nala as a promising lead molecule for the development of novel analgesics targeting Nav1.8,which might be suitable for treating a wide range of human pain pathologies.

关键词： Nav1.8 snake venom peptide antinociceptive

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Quantum anomalous Hall effect and giant Rashba spin-orbit splitting in graphene system co-doped with boron and 5d transition-metal atoms

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Frontiers of physics 2018年第5期13卷 79-86页

作者： xinzhou Deng Hualing Yang Shifei Qi Xiaohong Xu Zhenhua Qiao CQD Hefei National Laboratory for Physical Sciences at Microscale and Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of China Hefei 230026 China CAS Key Laboratory of Strongly-Coupled Quantum Matter Physics and Department of Physics University of Science and Technology of China Hefei 230026 China School of Chemistry and Materials Science Shanxi Normal University Linfen 041004 China

Quantum anomalous Hall effect （QAHE） is a fundamental quantum transport phenomenon in con- densed matter physics. Until now, the QAHE has only been experimentally realized for Cr/V-doped （Bi, Sb）2We3 but at an extremely low observational temperature, thereby limiting its potential appli- cation in dissipationless quantum electronics. By employing first-principles calculations, we study the electronic structures of graphene co-doped with 5d transition metal and boron atoms based on a com- pensated n-p co-doping scheme. Our findings are as follows： i） The electrostatic attraction between the n- and p-type dopants effectively enhances the adsorption of metal adatoms and suppresses their undesirable clustering, ii） Hf-B and Os-B co-doped graphene systems can establish long-range ferro- magnetic order and open larger nontrivial band gaps because of the stronger spin-orbit coupling with the non-vanishing Berry curvatures to host the high-temperature QAHE. iii） The calculated Rashba splitting energies in Re-B and Pt-B co-doped graphene systems can reach up to 158 and 85 meV, re- spectively, which are several orders of magnitude higher than the reported intrinsic spin-orbit coupling strength.

关键词： graphene quantum anomalous Hall effect spin-orbit coupling

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