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From 0D to 3D:Hierarchical structured high-performance free-standing silicon anodes based on binder-induced topological network architecture

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Journal of Energy Chemistry 2024年第6期93卷 16-23,I0002页

作者： Yihong Tong Ruicheng Cao Guanghui Xu Yifeng xia Hongyuan Xu Hong Jin Hui Xu xi’an jiaotong university suzhou Academy Suzhou 215123JiangsuChina Nano Science and Technology institute University of Science and Technology of ChinaSuzhou 215123JiangsuChina

Free-standing silicon anodes with high proportion of active materials have aroused great attention;however,the mechanical stability and electrochemical performance are severely suppressed.Herein,to resolve the appeal issues,a free-standing anode with a"corrugated paper"shape on micro-scale and a topological crosslinking network on the submicron and nano-scale is designed.Essentially,an integrated three-dimensional electrode structure is constructed based on robust carbon nanotubes network with firmly anchored SiNPs via forming interlocking junctions.In which,the hierarchical interlocking structure is achieved by directional induction of the binder,which ensures well integration during cycling so that significantly enhances mechanical stability as well as electronic and ionic conductivity of electrodes.Benefiting from it,this anode exhibits outsta nding performance under harsh service conditions including high Si loading,ultrahigh areal capacity(33.2 mA h cm^(-2)),and high/low temperatures(-15-60℃),which significantly extends its practical prospect.Furthermore,the optimization mechanism of this electrode is explored to verify the crack-healing and structure-integration maintaining along cycling via a unique self-stabilization process.Thus,from both the fundamental and engineering views,this strategy offers a promising path to produce high-performance free-standing electrodes for flexible device applications especially facing volume effect challenges.

关键词： Topological network Self-stabilization Flexibility Free-standing Silicon anode

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Random fractal-based computational design of an ice-ray (IR) lattice shell structure

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Frontiers of Architectural Research 2024年第2期13卷 406-424页

作者： Iasef Md Rian Department of Architecture Xi'an Jiaotong-Liverpool UniversitySuzhou 215123China

Chinese ice-ray (IR) lattices, known for their intricate and visually fascinating random patterns as decorative elements in traditional 18th-century Chinese window design, exhibit underlying stiffness as latticed window fences. Such unique patterns represent a new morphology within the family of stochastic lattices. However, the latent structural potential within the random patterns of ice-ray lattices remains largely unexplored, particularly in the context of lattice shell design. This study systematically studies the geometric qualities of ice-ray lattice patterns and develops an algorithm to model these patterns for ice-ray lattice shell design. Subsequently, it assesses the structural feasibility and effectiveness of these lattice shells in comparison to conventional gridshells. The practicality of constructing random lattice shells using digital fabrication tools is also explored. Employing fractal geometry as a foundational framework, this research not only offers insights into the potential of ice-ray lattices for innovative lattice shell design but also introduces a new structural morphology to the field, expanding the possibilities of incorporating stochastic patterns in lattice shell design. Ultimately, it opens up new opportunities for innovative lattice shell designs, emphasizing the potential of stochastic patterns in structural applications.

关键词： Ice-ray pattern Fractals Random Lattice shells Computational design Digital fabrication

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The Role of Childhood Circumstances in Healthy Aging Inequalities Among Older Adults—China,2011–2020

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China CDC weekly 2024年第11期6卷 208-212,I0004-I0007页

作者： Peng Nie xili Lin Lanlin Ding School of Economics and Finance Xi’an Jiaotong UniversityXi’an CityShaanxi ProvinceChina Global Health institute Xi’an Jiaotong University Health Science CenterXi’an CityShaanxi ProvinceChina National School of Development Peking UniversityBeijingChina

What is already known about this topic?Addressing health disparities is a worldwide priority,with a well-established acknowledgment of the influence of childhood circumstances on these discrepancies.In China,particularly among the elderly,health inequalities are a notable concern.What is added by this report?The inequality in healthy aging has increased from 2011 to 2020,both in general and concerning childhood factors.Nevertheless,the impact of early-life healthcare access and parental health behaviors on healthy aging gaps has reduced among older adults in better health within the top segment of healthy aging.What are the implications for public health practice?Efforts towards reducing regional health disparities and improving healthcare access for children,along with promoting the health and well-being of parents,especially in economically disadvantaged households,are crucial policy considerations.

关键词： ledgment inequalities circumstances

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Heat management technology for solid-state high voltage and high repetitive pulse generators:Towards better effects and reliability

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High Voltage 2024年第1期9卷 2-21页

作者： Yanan Wang Linyuan Ren Zihao Yang Saikang Shen Zichen Deng Qi Yuan Weidong Ding Zhenjie Ding School of Electrical Engineering Xi'an Jiaotong UniversityXi'anChina School of Electronic and Information Engineering Xi'an Jiaotong UniversityXi'anChina

Solid-state high voltage high repetitive pulse generators have a broad prospect in various applications.The high power and high-frequency operation of the pulse generator suffer from the massive heat dissipation problem,which limits the improvement of the output parameters and even affects the lifetime.This article focuses on heat management technology for high voltage high repetitive pulse generators.Firstly,the typical circuit topology of the high repetitive pulse generators was summarised.From the perspective of different application requirements,the demands of the heat management design were concluded.Moreover,the heat generation characteristics and difficulties of solid-state high voltage high repetitive pulse generators were analysed.Then,the different stateof-art cooling techniques were reviewed,and their applicability and limitations for the high voltage high repetitive generators were discussed.Finally,a flow chart for heat management design was given.

关键词： pulse state high

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Acoustic carrier signal transmission technology and its potential for in-site monitoring of sliding electrical contact used in gas-insulated switchgear/gas-insulated transmission line

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High Voltage 2024年第2期9卷 287-295页

作者： Chen Chen Yutong Zhang Huijun Zhao Zongren Peng Qingyu Wang xi'an jiaotong university Xi'anChina

A wireless signal transmission technology based on acoustic carrier is proposed,which overcomes the limitation of electromagnetic signal shielding and shows great potential for in-site monitoring of sliding electrical contact used in gas-insulated switchgear(GIS)/gasinsulated transmission line(GIL).Here,the state parameter of the sliding electrical contact is modulated onto the frequency domain of an ultrasound wave.As a mechanical wave,the ultrasonic wave is immune to electromagnetic shielding,so that it could carry the sensing signal to penetrate the metal shielding layer and transmit to the external terminals of GIS/GIL.The principle and signal modulation process of the acoustic carrier based transmission system have been demonstrated in detail.Both simulation and experiment have been conducted to analyse the system characteristics as well as optimise the system configuration.As a proof-of-concept application,the in situ and on-line monitoring of the thermal rise of a slide electrical contact both in a current loading equivalent model and a prototype of GIS is demonstrated.Experimental results fit well with the physical process,and show a good measurement accuracy of 0.6%and tem-perature sensitivity of 400 Hz/℃.

关键词： electrical potential Acoustic

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Femtosecond laser fabrication of 3D vertically aligned micro-pore network on thick-film Li4Ti5O12 electrode for high-performance lithium storage

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Journal of Energy Chemistry 2024年第8期95卷 250-262页

作者： Quansheng Li xiaofei Sun Xuesong Mei Lingzhi Wang Minxing Yang Jianlei Cui Wenjun Wang State Key Laboratory for Manufacturing System Engineering Xi'an Jiaotong University Shaanxi Key Laboratory of Intelligent Robots Xi'an Jiaotong University School of Mechanical Engineering Xi'an Jiaotong University

The development of energy storage devices with high energy density relies heavily on thick film electrodes, but it is challenging due to the limited ion transport kinetics inherent in thick electrodes. Here,we report on the preparation of a directional vertical array of micro-porous transport networks on LTO electrodes using a femtosecond laser processing strategy, enabling directional ion rapid transport and achieving good electrochemical performance in thick film electrodes. Various three-dimensional(3D)vertically aligned micro-pore networks are innovatively designed, and the structure, kinetics characteristics, and electrochemical performance of the prepared ion transport channels are analyzed and discussed by multiple characterization and testing methods. Furthermore, the rational mechanisms of electrode performance improvement are studied experimentally and simulated from two aspects of structural mechanics and transmission kinetics. The ion diffusion coefficient, rate performance at 60 C,and electrode interface area of the laser-optimized 60-15% micro-porous transport network electrodes increase by 25.2 times, 2.2 times, and 2.15 times, respectively than those of untreated electrodes.Therefore, the preparation of 3D micro-porous transport networks by femtosecond laser on ultra-thick electrodes is a feasible way to develop high-energy batteries. In addition, the unique micro-porous transport network structure can be widely extended to design and explore other high-performance energy materials.

关键词： Femtosecond laser Ion transport kinetics Laser processing Micro-porous transport networks Thick film electrodes

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Broad-spectrum ginsentides are principal bioactives in unraveling the cure-all effects of ginseng

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Acta Pharmaceutica Sinica B 2024年第2期14卷 653-666页

作者： Shining Loo Antony Kam Bamaprasad Dutta xiaohong Zhang Nan Feng Siu Kwan Sze Chuan-Fa Liu xiaoliang Wang James P.Tam School of Biological Sciences Nanyang Technological UniversitySingapore 637551Singapore Academy of Pharmacy Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China Department of Biological Sciences Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China institute of Materia Medica Chinese Academy of Medical SciencesBeijing 100050China Department of Health Sciences Brock UniversityNiagara RegionON L2S 3A1Canada

Stress and illness connection is complex and involves multiple physiological systems.Panax ginsengs,reputed for their broad-spectrum“cure-all”effect,are widely prescribed to treat stress and related illnesses.However,the identity of ginseng’s“cure-all”medicinal compounds that relieve stress remains unresolved.Here,we identify ginsentides as the principal bioactives that coordinate multiple systems to restore homeostasis in response to stress.Ginsentides are disulfide-rich,cell-penetrating and proteolytic-stable microproteins.Using affinity-enrichment mass spectrometry target identification together with in vitro,ex vivo and in vivo validations,we show that highly purified or synthetic ginsentides promote vasorelaxation by producing nitric oxide through endothelial cells via intracellular PI3K/Akt signaling pathway,alleviate a1-adrenergic receptor overactivity by reversing phenylephrine-induced constriction of aorta,decrease monocyte adhesion to endothelial cells via CD166/ESAM/CD40 and inhibit P2Y12 receptors to reduce platelet aggregation.Orally administered ginsentides were effective in animal models to reduce ADP-induced platelet aggregation,to prevent collagen and adrenalineinduced pulmonary thrombosis as well as anti-stress behavior of tail suspension and forced swimming tests in mice.Together,these results strongly suggest that ginsentides are the principal panacea compounds of ginsengs because of their ability to target multiple extra-and intra-cellular proteins to reverse stress-induced damages.

关键词： Ginseng Cysteine-rich peptides Microproteins Cure-all Stress Homeostasis

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ROS-responsive hydrogels with spatiotemporally sequential delivery of antibacterial and anti-inflammatory drugs for the repair of MRSA-infected wounds

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Regenerative Biomaterials 2024年第1期3卷 119-131页

作者： Bowen Qiao Jiaxin Wang Lipeng Qiao Aziz Maleki Yongping Liang Baolin Guo Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research College of StomatologyXi’an Jiaotong UniversityXi’an 710049China State Key Laboratory for Mechanical Behavior of Materials Frontier Institute of Science and TechnologyXi’an Jiaotong UniversityXi’an 710049China Zanjan Pharmaceutical Nanotechnology Research Center(ZPNRC) Zanjan 45139-56184Iran Department of Orthopaedics The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061People’s Republic of China

For the treatment of MRSA-infected wounds,the spatiotemporally sequential delivery of antibacterial and anti-inflammatory drugs is a promising strategy.In this study,ROS-responsive HA-PBA/PVA(HPA)hydrogel was prepared by phenylborate ester bond cross-linking between hyaluronic acid-grafted 3-amino phenylboronic acid(HA-PBA)and polyvinyl alcohol(PVA)to achieve spatiotemporally controlled release of two kinds of drug to treat MRSA-infected wound.The hydrophilic antibiotic moxifloxacin(M)was directly loaded in the hydrogel.And hydrophobic curcumin(Cur)with anti-inflammatory function was first mixed with Pluronic F127(PF)to form Cur-encapsulated PF micelles(Cur-PF),and then loaded into the HPA hydrogel.Due to the different hydrophilic and hydrophobic nature of moxifloxacin and Cur and their different existing forms in the HPA hydrogel,the final HPA/M&Cur-PF hydrogel can achieve different spatiotemporally sequential delivery of the two drugs.In addition,the swelling,degradation,self-healing,antibacterial,anti-inflammatory,antioxidant property,and biocompatibility of hydrogels were tested.Finally,in the MRSA-infected mouse skin wound,the hydrogel-treated group showed faster wound closure,less inflammation and more collagen deposition.Immunofluorescence experiments further confirmed that the hydrogel promoted better repair by reducing inflammation(TNF-a)and promoting vascular(VEGF)regeneration.In conclusion,this HPA/M&CurPF hydrogel that can spatiotemporally sequential deliver antibacterial and anti-inflammatory drugs showed great potential for the repair of MRSA-infected skin wounds.

关键词： MRSA-infected wounds spatiotemporally sequential delivery antibacterial anti-inflammatory

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A 28/56 Gb/s NRZ/PAM-4 dual-mode transceiver with 1/4 rate reconfigurable 4-tap FFE and half-rate slicer in a 28-nm CMOS

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Journal of Semiconductors 2024年第6期45卷 35-46页

作者： Yukun He Zhao Yuan Kanan Wang Renjie Tang Yunxiang He xian Chen Zhengyang Ye xiaoyan Gui School of Microelectronics Xi’an Jiaotong UniversityXi’an 710049China

A 28/56 Gb/s NRZ/PAM-4 dual-mode transceiver(TRx)designed in a 28-nm complementary metal-oxide-semiconduc-tor(CMOS)process is presented in this article.A voltage-mode(VM)driver featuring a 4-tap reconfigurable feed-forward equal-izer(FFE)is employed in the quarter-rate transmitter(TX).The half-rate receiver(RX)incorporates a continuous-time linear equal-izer(CTLE),a 3-stage high-speed slicer with multi-clock-phase sampling,and a clock and data recovery(CDR).The experimen-tal results show that the TRx operates at a maximum speed of 56 Gb/s with chip-on board(COB)assembly.The 28 Gb/s NRZ eye diagram shows a far-end vertical eye opening of 210 mV with an output amplitude of 351 mV single-ended and the 56 Gb/s PAM-4 eye diagram exhibits far-end eye opening of 33 mV(upper-eye),31 mV(mid-eye),and 28 mV(lower-eye)with an output amplitude of 353 mV single-ended.The recovered 14 GHz clock from the RX exhibits random jitter(RJ)of 469 fs and deterministic jitter(DJ)of 8.76 ps.The 875 Mb/s de-multiplexed data features 593 ps horizontal eye opening with 32.02 ps RJ,at bit-error rate(BER)of 10-5(0.53 UI).The power dissipation of TX and RX are 125 and 181.4 mW,respectively,from a 0.9-V sup-ply.

关键词： transceiver(TRx) feed-forward equalizer(FFE) clock and data recovery(CDR) continuous time linear equalizer(CTLE)

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Knocking down AR promotes osteoblasts to recruit prostate cancer cells by altering exosomal circ-DHPS/miR-214-3p/CCL5 pathway

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Asian Journal of Andrology 2024年第2期26卷 195-204页

作者： Zhao Yang Jia-Qi Chen Tian-Jie Liu Yu-Le Chen Zhen-Kun Ma Yi-Zeng Fan Zi-xi Wang Shan Xu Ke Wang xin-Yang Wang Lei Li Hong-Jun xie Department of Urology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061China

Tumor-derived exosomes have been shown to play a key role in organ-specific metastasis,and the androgen receptor regulates prostate cancer(PCa)progression.It is unclear whether the androgen receptor regulates the recruitment of prostate cancer cells to the bone microenvironment,even bone metastases,through exosomes.Here,we found that exosomes isolated from PCa cells after knocking down androgen receptor(AR)or enzalutamide treatment can facilitate the migration of prostate cancer cells to osteoblasts.In addition,AR silencing or treatment with the AR antagonist enzalutamide may increase the expression of circular RNA-deoxyhypusine synthase(circ-DHPS)in PCa cells,which can be transported to osteoblasts by exosomes.Circ-DHPS acts as a competitive endogenous RNA(ceRNA)against endogenous miR-214-3p to promote C-C chemokine ligand 5(CCL5)levels in osteoblasts.Increasing the level of CCL5 in osteoblasts could recruit more PCa cells into the bone microenvironment.Thus,blocking the circ-DHPS/miR-214-3p/CCL5 signal may decrease exosome-mediated migration of prostate cancer cells to osteoblasts.

关键词： androgen receptor circRNA exosome prostate cancer

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