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Clinical feasibility of laparoscopic left lateral segment liver resection with magnetic anchor technique:The first clinical study from China

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1336-1343页

作者： Miao-Miao Zhang Ji-Gang Bai Dong Zhang Jie Tao Zhi-Min Geng Zhuo-Qun Li Yu-xiang Ren Yu-HanZhang Yi Lyu xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Shaanxi Provincial Key Laboratory of Magnetic Medicine The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Zonglian College Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Qide College Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Magnetic anchor technique(MAT)has been applied in laparoscopic cholecystectomy and laparoscopic appendectomy,but has not been reported in laparoscopic partial hepatectomy.AIM To evaluate the feasibility of the MAT in laparoscopic left lateral segment liver resection.METHODS Retrospective analysis was conducted on the clinical data of eight patients who underwent laparoscopic left lateral segment liver resection assisted by MAT in our department from July 2020 to November 2021.The Y-Z magnetic anchor devices(Y-Z MADs)was independently designed and developed by the author of this paper,which consists of the anchor magnet and magnetic grasping apparatus.Surgical time,intraoperative blood loss,intraoperative accidents,operator experience,postoperative incision pain score,postoperative complications,and other indicators were evaluated and analyzed.RESULTS All eight patients underwent a MAT-assisted laparoscopic left lateral segment liver resection,including three patients undertaking conventional 5-port and five patients having a transumbilical single-port operation.The mean operation time was 138±34.32 min(range 95-185 min)and the mean intraoperative blood loss was 123±88.60 mL(range 20-300 mL).No adverse events occurred during the operation.The Y-Z MADs showed good workability and maneuverability in both tissue and organ exposure.In particular,the operators did not experience either a“chopstick”or“sword-fight”effect in the single-port laparoscopic operation.CONCLUSION The results show that the MAT is safe and feasible for laparoscopic left lateral segment liver resection,especially,exhibits its unique abettance for transumbilical single-port laparoscopic left lateral segment liver resection.

关键词： Magnetosurgery/magnetic surgery Magnetic anchor technique Laparoscopic hepatectomy Transumbilical singleport laparoscopy Magnet

Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development

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Neural Regeneration Research 2025年第3期20卷 900-912页

作者： Baoqi Hu Rui Wang Hanyue Zhang xiou Wang Sijia Zhou Bo Ma Yan Luan xin Wang xinlin Chen Zhichao Zhang Qianyan Kang Department of Ophthalmology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology The First Affiliated Hospital of Northwest UniversityXi’anShaanxi ProvinceChina Institute of Neurobiology Xi’an Jiaotong University Health Science CenterXi’anShaanxi ProvinceChina

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures.However,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development studies.Thus,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo retina.In this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in vivo.Initially,we used SOX2 and PAX6 immunostaining to identify retinal progenitor cells.We then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,respectively.Ki-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between groups.Additionally,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,respectively.The timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant retinas.Our study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina development.The findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation.

关键词： bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells

A Degree Condition for Graphs Having All(a,b)-parity Factors

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 656-664页

作者： Hao-dong LIU Hong-liang LU School of Mathematics and Statistics Xi'an Jiaotong UniversityXi'an 710049China

Let a and b be positive integers such that a≤b and a≡b(mod 2).We say that G has all(a,b)-parity factors if G has an h-factor for every function h:V(G)→{a,a+2,…,b-2,b} with b|V(G)| even and h(v)≡b(mod 2) for all v∈V(G).In this paper,we prove that every graph G with n≥2(b+1)(a+b) vertices has all(a,b)-parity factors if δ(G)≥(b^(2)-b)/a,and for any two nonadjacent vertices u,v ∈V(G),max{d_(G)(u),d_(G)(v)}≥bn/a+b.Moreover,we show that this result is best possible in some sense.

关键词： degree condition all(a,b)-factors

Boosting charge transfer via interface charge reconstruction between amorphous NiFe-LDH and crystalline NiCo_(2)O_(4)for efficient alkaline water/seawater oxidation

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Nano Research 2024年第6期17卷 4856-4863页

作者： Zhonghang xing Yi Zhao Yunhai Wang xiaohe Liu Zhiqiang Guo Qingyun Chen International Research Center for Renewable Energy and State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong UniversityXi’an 710049China Department of Environmental science and Engineering Xi’an Jiaotong UniversityXi’an 710049China China School of Geology and Environment Xi’an University of Science and TechnologyXi’an 710049China Changqing Engineering Design Co. Ltd.Xi’an 710018China

Electrocatalysts with optimal efficiency and durability for the oxygen evolution reaction(OER)are becoming increasingly important as the demand for alkaline water/seawater electrolysis technology grows.Herein,a novel rose-shaped NiFe-layered double hydroxide(LDH)/NiCo_(2)O_(4)composed of amorphous wrinkled NiFe-LDH and highly crystalline NiCo_(2)O_(4)was synthesized with rich heterointerfaces.Many unsaturated metal sites are generated due to significant charge reconstruction at the heterointerface between the crystalline and amorphous phases.These metal sites could trigger and provide more active sites.The density functional theory(DFT)reveals that a new charge transfer channel(Co-Fe)was formed at the heterointerface between NiFe-LDH as electron acceptor and NiCo_(2)O_(4)as electron donor.The new charge transfer channel boosts interfacial charge transfer and enhances catalytic efficiency.The NiFe-LDH/NiCo_(2)O_(4)/nickel foam(NF)drives current densities of 10 and 100 mA·cm−2 with overpotentials of 193 and 236 mV,respectively.The composite electrode demonstrates a fast turnover frequency(0.0143 s−1)at 1.45 V vs.RHE(RHE=reversible hydrogen electrode),which is 5.5 times greater than pure NiCo_(2)O_(4),suggesting its superior intrinsic activity.Additionally,NiFe-LDH/NiCo_(2)O_(4)/NF electrode exhibited negligible degradation after 150 h of uninterrupted running in alkaline seawater oxidation.This study introduces a method for preparing high-efficiency electrocatalysts utilized in alkaline water/seawater electrolysis.

关键词： NiFe-layered double hydroxide(LDH)/NiCo_(2)O_(4)/nickel foam(NF) heterogeneous interfaces charge reconstruction water/seawater electrolysis

Regulating the conductance of tungsten diselenide by oxygen plasma and improving its electrical stability by encapsulation

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Nano Research 2024年第4期17卷 3253-3260页

作者： Zhaofang Cheng Shaodan He Shimin Zhang Shijun Duan Min Wang Ziyu Liu Rong Zhang Wenya Qiang Xudong Zhang Minggang xia MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter School of PhysicsXi’an Jiaotong UniversityXi’an 710049China Department of Applied Physics School of PhysicsXi’an Jiaotong UniversityXi’an 710049China Shaanxi Province Key Laboratory of Quantum Information and Optoelectronic Quantum Devices School of PhysicsXi’an Jiaotong UniversityXi’an 710049China

Two-dimensional(2D)tungsten selenide(WSe_(2))is promising candidate material for future electronic applications,owing to its potential for ultimate device scaling.For improving the electronic performance of WSe_(2)-based field-effect transistors(FETs),the modification of surface properties is essential.In this study,the seamless structural phase transition in WSe_(2) lattice is achieved by soft oxygen plasma,regulating the electrical conductance of WSe_(2)-based FETs.We found that during the soft oxygen plasma treatment with optimal processing time,the generated oxygen ions can substitute some selenium atoms and thus locally modify the bond length,inducing 2H→1T phase transition in WSe_(2) with seamless interfaces.The mosaic structures have been proven to tailor the electronic structure and increase the hole carrier concentration inside WSe_(2),significantly increasing the channel conductance of WSe_(2) FETs.With the further increase of the oxygen plasma treatment time,the creation of more selenium vacancy defects leads to the electronic doping,resulting in the reduction of conductance.Benefiting from the hexagonal boron nitride(h-BN)encapsulation to interrupt the partial structural relaxation from 1T to 2H phase,our WSe_(2) FET exhibits high electronic stability with conductance of 6.8×10^(-4) S,which is about four orders of magnitude higher than 2H WSe_(2)(5.8×10^(-8) S).This study could further broaden the WSe_(2) FETs in applications for functionalization and integration in electronics.

关键词： tungsten selenide(WSe2) structural phase transition oxygen plasma conductance hexagonal boron nitride(h-BN)encapsulation

Learning to sample initial solution for solving 0-1 discrete optimization problem by local search

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science China Mathematics 2024年第6期67卷 1317-1340页

作者： xin Liu Jianyong Sun Zongben Xu School of Mathematics and Statistics Xi’an Jiaotong UniversityXi’an710049China

Local search methods are convenient alternatives for solving discrete optimization problems(DOPs).These easy-to-implement methods are able to find approximate optimal solutions within a tolerable time limit.It is known that the quality of the initial solution greatly affects the quality of the approximated solution found by a local search method.In this paper,we propose to take the initial solution as a random variable and learn its preferable probability distribution.The aim is to sample a good initial solution from the learned distribution so that the local search can find a high-quality solution.We develop two different deep network models to deal with DOPs established on set(the knapsack problem)and graph(the maximum clique problem),respectively.The deep neural network learns the representation of an optimization problem instance and transforms the representation to its probability vector.Experimental results show that given the initial solution sampled from the learned probability distribution,a local search method can acquire much better approximate solutions than the randomly-sampled initial solution on the synthesized knapsack instances and the Erd?s-Rényi random graph instances.Furthermore,with sampled initial solutions,a classical genetic algorithm can achieve better solutions than a random initialized population in solving the maximum clique problems on DIMACS instances.Particularly,we emphasize that the developed models can generalize in dimensions and across graphs with various densities,which is an important advantage on generalizing deep-learning-based optimization algorithms.

关键词： discrete optimization deep learning graph convolutional network local search

Flexible pressure sensors with ultrahigh stress tolerance enabled by periodic microslits

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Microsystems & Nanoengineering 2024年第1期10卷 301-311页

作者： Song Wang Chenying Wang Yifan Zhao Yujing Zhang Yaxin Zhang xiangyue Xu Qijing Lin Kai Yao Yuheng Wang Feng Han Yu Sun Zhuangde Jiang State Key Laboratory for Manufacturing Systems Engineering International Joint Laboratory for Micro/Nano Manufacturing and Measurement TechnologiesSchool of Mechanical EngineeringXi’an Jiaotong UniversityXi’anChina State Key Laboratory for Manufacturing Systems Engineering International Joint Laboratory for Micro/Nano Manufacturing and Measurement TechnologiesSchool of Instrument Science and TechnologyXi’an Jiaotong UniversityXi’anChina The Faculty of Electrical Engineering and Computer science Ningbo UniversityNingboChina Department of Mechanical and Industrial Engineering University of TorontoTorontoCanada

Stress tolerance plays a vital role in ensuring the effectiveness of piezoresistive sensing films used in flexible pressure sensors.However,existing methods for enhancing stress tolerance employ dome-shaped,wrinkle-shaped,and pyramidal-shaped microstructures in intricate molding and demolding processes,which introduce significant fabrication challenges and limit the sensing performance.To address these shortcomings,this paper presents periodic microslits in a sensing film made of multiwalled carbon nanotubes and polydimethylsiloxane to realize ultrahigh stress tolerance with a theoretical maximum of 2.477 MPa and a sensitivity of 18.092 kPa−1.The periodic microslits permit extensive deformation under high pressure(e.g.,400 kPa)to widen the detection range.Moreover,the periodic microslits also enhance the sensitivity based on simultaneously exhibiting multiple synapses within the sensing interface and between the periodic sensing cells.The proposed solution is verified by experiments using sensors based on the microslit strategy for wind direction detection,robot movement sensing,and human health monitoring.In these experiments,vehicle load detection is achieved for ultrahigh pressure sensing under an ultrahigh pressure of over 400 kPa and a ratio of the contact area to the total area of 32.74%.The results indicate that the proposed microslit strategy can achieve ultrahigh stress tolerance while simplifying the fabrication complexity of preparing microstructure sensing films.

关键词： robot shaped stress

Miura origami based reconfigurable polarization converter for multifunctional control of electromagnetic waves

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Photonics Research 2024年第3期12卷 581-586页

作者： ZHIBIAO ZHU YONGFENG LI ZHE QIN LIxiN JIANG WENJIE WANG HONGYA CHEN JIAFU WANG YONGQIANG PANG SHAOBO QU Shaanxi Key Laboratory of Artificially-Structured Functional Materials and Devices Air Force Engineering UniversityXi’an 710051China School of Electronic science and Engineering Xi’an Jiaotong UniversityXi’an 710049China

Polarization is one of the basic characteristics of electromagnetic(EM)waves,and its flexible control is very important in many practical applications.At present,most of the multifunction polarization metasurfaces are electrically tunable based on PIN and varactor diodes,which are easy to operate and have strong real-time performance.However,there are still some problems in them,such as few degrees of freedom of planar structure control,complex circuit,bulky sample,and high cost.In view of these shortcomings,this paper proposes a Miura origami based reconfigurable polarization conversion metasurface for multifunctional control of EM waves.The interaction between the electric dipoles is changed by adjusting the folding angleθ,thereby tuning the operating frequency of the polarization conversion and the polarization state of the reflected wave.This mechanical control method brings more degrees of freedom to manipulate EM waves.And the processed sample is with lightweight and low cost.To verify the performance of the proposed origami polarization converter,a Miura origami structure loaded with metal split rings is designed and fabricated.The operating frequency of the structure can be tuned in different folding states.In addition,by controlling the folding angleθ,linear-to-linear and linear-to-circular polarization converters can be realized at different folding states.The proposed Miura origami polarization conversion metasurface provides a new idea for reconfigurable linear polarization conversion and multifunctional devices.

关键词： polarization reconfigurable tuning

Bacteria-responsive programmed self-activating antibacterial hydrogel to remodel regeneration microenvironment for infected wound healing

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National science Review 2024年第4期11卷 254-270页

作者： Yutong Yang Jiaxin Wang Shengfei Huang Meng Li Jueying Chen Dandan Pei Zhen Tang Baolin Guo State Key Laboratory for Mechanical Behavior of Materials and Frontier Institute of science and Technology and Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine ResearchCollege of Stomatology Xi'an Jiaotong University Department of Orthopedics Tangdu Hospital Fourth Military Medical University Department of Orthopedics The First Affiliated Hospital of Xi'an Jiaotong University

There is still an urgent need to develop hydrogels with intelligent antibacterial ability to achieve on-demand treatment of infected wounds and accelerate wound healing by improving the regeneration microenvironment. We proposed a strategy of hydrogel wound dressing with bacteria-responsive self-activating antibacterial property and multiple nanozyme activities to remodel the regeneration microenvironment in order to significantly promote infected wound healing. Specifically, p H-responsive H2O2self-supplying composite nanozyme（MSCO） and p H/enzyme-sensitive bacteria-responsive triblock micelles encapsulated with lactate oxidase（PPEL） were prepared and encapsulated in hydrogels composed of L-arginine-modified chitosan（CA） and phenylboronic acid-modified oxidized dextran（ODP） to form a cascade bacteria-responsive self-activating antibacterial composite hydrogel platform. The hydrogels respond to multifactorial changes of the bacterial metabolic microenvironment to achieve on-demand antibacterial and biofilm eradication through transformation of bacterial metabolites, and chemodynamic therapy enhanced by nanozyme activity in conjunction with self-driven nitric oxide（NO） release. The composite hydrogel showed 'self-diagnostic' treatment for changes in the wound microenvironment.Through self-activating antibacterial therapy in the infection stage to self-adaptive oxidative stress relief and angiogenesis in the post-infection stage, it promotes wound closure, accelerates wound collagen deposition and angiogenesis, and completely improves the microenvironment of infected wound regeneration, which provides a new method for the design of intelligent wound dressings.

关键词： bacterial response hydrogel dressing multiple nanozyme activity biofilm elimination infected motion wound healing