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Journal of Integrative medicine 2015年第2期13卷 61-64页

作者： Zhao-guo Li College of Foreign Languages Shanghai Normal University Secretariat of Translation Specialty Committee World Federation of Chinese Medicine Societies

The following is a brief analysis about some terms related to paediatrics in traditional chinese medicine （TCM） included in the WHO International Standard Terminologies on Traditional medicine in the Western Pacific Region （abbreviated as the WPRO Standard）EI~ and the Interna- tional Standard chinese-English Basic Nomenclature of chinese medicine compiled by the world federation of chinese medicine societies （abbreviated as the WFCMS Standard）, according to explanations made in the book entitled A Concise Dictionary of Traditional chinese medicinet,

关键词： linguistics terminology translation English terms, traditional chinese medicine paediatrics(TCM)

Comparative study on WHO Western Pacific Region and world federation of chinese medicine societies international standard terminologies on traditional medicine: Diseases in External medicine (Part 1)

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Journal of Integrative medicine 2013年第2期11卷 67-71页

作者： Zhao-guo Li Jian-ming Tan College of Foreign Languages Shanghai Normal University Secretariat of Translation Specialty Committee World Federation of Chinese Medicine Societies

External medicine, also frequently described as surgery, has a history as long as that of traditional chinese medicine （TCM）. There were important doctors in each dynasty who devoted themselves to the study and practice of external medicine. In TCM external medicine, diseases are named either according to their location （such as neck abscess and back carbuncle）, or viscera involved （such as intestinal abscess and lung abscess）, or causes （such as tetanus and chilblain, which are literally known respectively as wind damage of wound and sore caused by cold in TCM）, or shape （such as snake head boil and goose web wind）, or the color （such as erysipelas and vitiligo which are literally known respectively as red toxin and white skin wind）, etc.

关键词： lingrustics terminology translation Engish terms, traditional chinese medicine external medicine (TCM)

Expert Consensus on Integrated Traditional and Western medicine Prevention and Rehabilitation of Malignant Tumor During the Epidemics of Coronavirus Disease 2019(First Edition)Specialty Committee of Classical TCM Formula for Cancer Treatment and Research of world federation of chinese medicine societies

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world Journal of Integrated Traditional and Western medicine 2020年第3期6卷 70-78页

作者： FENG Li WANG Yu-guang HU Zuo-wei FAN Heng ZHANG Ying-wen YANG Chen-guang TANG Dongxin LU Wei-dong LIN Qing-zhong WANG Xiao-hui YIN Yu-kun LIU Li-xing Department of chinese medicine National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing100021China Department of Respiratory Disease Beijing Hospital of Traditional Chinese MedicineCapital Medical University Department of Oncology Wuhan No.1 Hospital Department of Traditional chinese medicine Union HospitalTongji Medical College of Huazhong University of Science and Technology Department of chinese with Western medicine Zhongnan Hospital of Wuhan UniversityWuhanChina Department of Oncology Shanxi Hospital of Traditional Chinese Medicine Department of Oncology The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Center for Integrative Therapies Dana-Farber Cancer InstituteHarvard Medical School Central Taiwan University of Science and Technology Department of Traditional Chinese MedicineFengyuan Hospital of Health Promotion Administration of TaiwanChina French federation of Digestive Cancer

Coronavirus Disease 2019(COVID-19)has caused a global outbreak and become a major public health *** January 20,2020,the announcement of National Health Commission(No.1 of 2020)included COVID-19 as a category B infectious disease in Law of the People's Republic of China on prevention and control of Infectious Diseases,and took preventing and controlling measures like those of category A infectious diseases^([1]).Tumor patients are more susceptible to infection because of their vulnerable nutritional state and systemic immunosuppressive state caused by antitumor treatments,such as radiotherapy,chemotherapy and surgery^([2]).Cancer patients had an estimated 2-fold increased risk of COVID-19 than the general population according to the Report of the WHO-China Joint Mission on COVID-19^([3]);The incidence rate of COVID-19 in cancer patients in Wuhan is 0.79%,while the general population is 0.37%in the same period^([4]).And the COVID-19 cancer patients were with higher risk to become severe condition and worse prognosis,especially in those patients who received chemotherapy or surgery recently,than those without cancer^([5-6]).In addition,the inconvenience for patients going out to see doctors also leads to the delay of diagnosis and *** a result,under the current severe situation,scientific and effective management measures and reasonable responsive strategies are urgently needed to minimize the impact of the epidemic on tumor patients^([7-9]).Especially recently,the outbreak continues to spread in many countries around the *** Health Organization(WHO)believes the COVID-19 epidemic has the characteristics of a pandemic,calling on all countries to take urgent and active *** such circumstances,experts organized by Classical Traditional chinese medicine Prescription for Cancer Treatment and Research Committee of world federation of chinese medicine societies,discussed and formed"Expert Consensus on Integrated Traditional and Western medicine P

关键词： COVID-19 Oncology Traditional chinese medicine

Comparative study on WHO Western Pacific Region and world federation of chinese medicinesocieties international standard terminologies ontraditional medicine: Diseases of Gynecology andObstetrics(Part 2)

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Journal of Integrative medicine 2014年第5期12卷 397-400页

作者： Zhao-guo Li College of Foreign Languages Shanghai Normal University Secretariat of Translation Specialty Committee World Federation of Chinese Medicine Societies

The following is the second discussion about how to understand and translate the names of diseases in tradi- tional chinese medicine （TCM） gynecology and obstetrics included in WHO International Standard Terminologies on Traditional medicine in the Western Pacific Region （abbreviated as the WPRO Standard） and the International Standard chinese-English Basic Nomenclature of chinese medicine compiled by world federation of chinese medicine societies （abbreviated as the WFCM Standard） , according to explanations made in the book entitled A Concise Dictionary of Traditional chinese medicine and the studies made in the book entitled International Standardization of English Translation of Traditional chinese medicine： Study of Theory, Summarization of Practice and Exploration of Methods.

关键词： linguistics terminology translation English terms, traditional chinese medicine gynecology-obstetrics (TCM)

T cell interactions with microglia in immune-inflammatory processes of ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1277-1292页

作者： Yuxiao Zheng Zilin Ren Ying Liu Juntang Yan Congai Chen Yanhui He Yuyu Shi Fafeng Cheng Qingguo Wang Changxiang Li Xueqian Wang School of Traditional chinese medicine Beijing University of Chinese MedicineBeijingChina Library Beijing University of Chinese MedicineBeijingChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

The primary mechanism of secondary injury after cerebral ischemia may be the brain inflammation that emerges after an ischemic stroke,which promotes neuronal death and inhibits nerve tissue *** the first immune cells to be activated after an ischemic stroke,microglia play an important immunomodulatory role in the progression of the *** an ischemic stroke,peripheral blood immune cells(mainly T cells)are recruited to the central nervous system by chemokines secreted by immune cells in the brain,where they interact with central nervous system cells(mainly microglia)to trigger a secondary neuroimmune *** review summarizes the interactions between T cells and microglia in the immune-inflammatory processes of ischemic *** found that,during ischemic stroke,T cells and microglia demonstrate a more pronounced synergistic ***1,Th17,and M1 microglia can co-secrete proinflammatory factors,such as interferon-γ,tumor necrosis factor-α,and interleukin-1β,to promote neuroinflammation and exacerbate brain ***2,Treg,and M2 microglia jointly secrete anti-inflammatory factors,such as interleukin-4,interleukin-10,and transforming growth factor-β,to inhibit the progression of neuroinflammation,as well as growth factors such as brain-derived neurotrophic factor to promote nerve regeneration and repair brain *** interactions between microglia and T cells influence the direction of the subsequent neuroinflammation,which in turn determines the prognosis of ischemic stroke *** trials have been conducted on the ways to modulate the interactions between T cells and microglia toward anti-inflammatory communication using the immunosuppressant fingolimod or overdosing with Treg cells to promote neural tissue repair and reduce the damage caused by ischemic ***,such studies have been relatively infrequent,and clinical experience is still *** summary,in ischemic stroke,T cell subsets and activated micro

关键词： brain immune inflammation interaction ischemic stroke mechanism microglia neuron secondary injury T cells

Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury

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Neural Regeneration Research 2025年第8期20卷 2153-2168页

作者： Xinyu You Lin Niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang National Key Laboratory of chinese medicine Modernization Tianjin University of Traditional Chinese MedicineTianjinChina Haihe Laboratory of Modern chinese medicine Tianjin University of Traditional Chinese MedicineTianjinChina First Teaching Hospital of Tianjin University of Traditional chinese medicine TianjinChina National Clinical Research Center for chinese medicine Acupuncture and Moxibustion TianjinChina

Traumatic brain injury is a prevalent disorder of the central nervous *** addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for patients with traumatic brain injury;however,the underlying pathogenesis remains unclear,and effective intervention methods are *** dysfunction is a significant consequence of traumatic brain *** the most densely innervated peripheral tissue in the body,the gut possesses multiple pathways for the establishment of a bidirectional“brain-gut axis”with the central nervous *** gut harbors a vast microbial community,and alterations of the gut niche contribute to the progression of traumatic brain injury and its unfavorable prognosis through neuronal,hormonal,and immune pathways.A comprehensive understanding of microbiota-mediated peripheral neuroimmunomodulation mechanisms is needed to enhance treatment strategies for traumatic brain injury and its associated *** comprehensively reviewed alterations in the gut microecological environment following traumatic brain injury,with a specific focus on the complex biological processes of peripheral nerves,immunity,and microbes triggered by traumatic brain injury,encompassing autonomic dysfunction,neuroendocrine disturbances,peripheral immunosuppression,increased intestinal barrier permeability,compromised responses of sensory nerves to microorganisms,and potential effector nuclei in the central nervous system influenced by gut ***,we reviewed the mechanisms underlying secondary biological injury and the dynamic pathological responses that occur following injury to enhance our current understanding of how peripheral pathways impact the outcome of patients with traumatic brain *** review aimed to propose a conceptual model for future risk assessment of central nervous system-related diseases while elucidating novel insights into the bidirectional effec

关键词： traumatic brain injury brain-gut-microbiome axis gut microbiota neuroimmune immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

Traditional chinese medicine in the treatment of Helicobacter pylorirelated gastritis:The mechanisms of signalling pathway regulations

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world Journal of Gastroenterology 2025年第3期31卷 11-28页

作者： Pei-Pei Zhang Liang Li Hao-Yu Qu Guang-Yu Chen Meng-Zhou Xie Yan-Kun Chen School of Traditional chinese medicine Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina Hunan Engineering Technology Research Center for Medicinal and Functional Food Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina Key Laboratory of Traditional chinese medicine Heart and Lung Syndrome Differentiation and Medicated Diet and Dietotherapy Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina School of Informatics Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Precision medicine Research and Development Center Zhuhai Institute of Advanced TechnologyChinese Academy of SciencesZhuhai 519000Guangdong ProvinceChina

Helicobacter pylori-associated gastritis(HPAG)is a common condition of the gastrointestinal ***,extensive and long-term antibiotic use has resulted in numerous adverse effects,including increased resistance,gastrointestinal dysfunction,and increased recurrence *** these concerns develop,traditional chinese medicine(TCM)may have *** is based on the concept of completeness and aims to eliminate pathogens and strengthen the *** has the potential to prevent this condition while also boosting the rate of Helicobacter pylori *** review elaborates on the mechanism of TCM treatment for HPAG based on cellular signalling pathways,which reflects the flexibility of TCM in treating diseases and the advantages of multi-level,multipathway,and multi-target treatments for HPAG.

关键词： Helicobacter pylori Helicobacter pylori-associated gastritis Traditional chinese medicine Signalling pathway Eliminate pathogens Strengthen the body

Exploring the interaction between the gut microbiota and cyclic adenosine monophosphate-protein kinase A signaling pathway:a potential therapeutic approach for neurodegenerative diseases

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Neural Regeneration Research 2025年第11期20卷 3095-3112页

作者： Fengcheng Deng Dan Yang Lingxi Qing Yifei Chen Jilian Zou Meiling Jia Qian Wang Runda Jiang Lihua Huang College of Pharmacy Chengdu University of Traditional Chinese MedicineChengduSichuan ProvinceChina State Key Laboratory of Southwestern chinese medicine Resources Chengdu University of Traditional Chinese MedicineChengduSichuan ProvinceChina

The interaction between the gut microbiota and cyclic adenosine monophosphate(cAMP)-protein kinase A(PKA)signaling pathway in the host's central nervous system plays a crucial role in neurological diseases and enhances communication along the gut–brain *** gut microbiota influences the cAMP-PKA signaling pathway through its metabolites,which activates the vagus nerve and modulates the immune and neuroendocrine ***,alterations in the cAMP-PKA signaling pathway can affect the composition of the gut microbiota,creating a dynamic network of microbial-host *** reciprocal regulation affects neurodevelopment,neurotransmitter control,and behavioral traits,thus playing a role in the modulation of neurological *** coordinated activity of the gut microbiota and the cAMP-PKA signaling pathway regulates processes such as amyloid-β protein aggregation,mitochondrial dysfunction,abnormal energy metabolism,microglial activation,oxidative stress,and neurotransmitter release,which collectively influence the onset and progression of neurological *** study explores the complex interplay between the gut microbiota and cAMP-PKA signaling pathway,along with its implications for potential therapeutic interventions in neurological *** pharmacological research has shown that restoring the balance between gut flora and cAMP-PKA signaling pathway may improve outcomes in neurodegenerative diseases and emotional *** can be achieved through various methods such as dietary modifications,probiotic supplements,chinese herbal extracts,combinations of chinese herbs,and innovative dosage *** findings suggest that regulating the gut microbiota and cAMP-PKA signaling pathway may provide valuable evidence for developing novel therapeutic approaches for neurodegenerative diseases.

关键词： cyclic adenosine monophosphate emotional disorders gut microbiota neurodegenerative diseases neurological diseases protein kinase A reciprocal regulation signaling pathway strategy therapies

The fundamental theory of traditional chinese medicine and the consideration in its research strategy

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Frontiers of medicine 2011年第2期5卷 208-211页

作者： Zhenji Li Chunbo Xu world federation of chinese medicine societies Beijing 100101China

Stressing the uniqueness and complexity of traditional chinese medicine(TCM)theory system,this paper analyzes the characteristics of TCM as a discipline from four perspectives:scientific nature,fundamental theory,clinical practice,and pharmacological *** suggests that when the research strategy of TCM theory is designed,the core theory of TCM should be emphasized on the theoretical research on TCM original thinking theory,TCM theory,chinese materia medica and formulas,acupuncture and moxibustion,meridians and collaterals,and other related *** and practitioners should ensure that the basic research on TCM theory is based on clinical practice,research methods(both traditional and contemporary)are exploited,and methodological innovation is *** rule of TCM development should be followed and the characteristics and advantages of TCM carried ***,the methods and theory of contemporary science and technology should be exploited to fulfill the goal of inheriting,enriching,and developing the fundamental theory of TCM.

关键词： fundamental theory traditional chinese medicine research strategy

The complex effects of miR-146a in the pathogenesis of Alzheimer's disease

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Neural Regeneration Research 2025年第5期20卷 1309-1323页

作者： Yunfan Long Jiajia Liu Yu Wang Haidong Guo Guohong Cui Department of Neurology Shanghai No.9 People’s HospitalShanghai Jiaotong University School of MedicineShanghaiChina Academy of Integrative medicine Shanghai University of Traditional Chinese MedicineShanghaiChina School of Integrative medicine Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Neurology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina

Alzheimer's disease is a neurodegenerative disorder characterized by cognitive dysfunction and behavioral *** plaques formed through the extracellular deposition of amyloid-βproteins,as well as neurofibrillary tangles formed by the intracellular deposition of hyperphosphorylated tau proteins,comprise two typical pathological features of Alzheimer's *** symptomatic treatment,there are no effective therapies for delaying Alzheimer's disease ***(miR)are small,non-coding RNAs that negatively regulate gene expression at the transcriptional and translational levels and play important roles in multiple physiological and pathological ***,miR-146a,a NF-κB-regulated gene,has been extensively implicated in the development of Alzheimer's disease through several *** has demonstrated substantial dysregulation of miR-146a both during the initial phases and throughout the progression of this *** R-146a is believed to reduce amyloid-βdeposition and tau protein hyperphosphorylation through the TLR/IRAK1/TRAF6 pathway;however,there is also evidence supporting that it can promote these processes through many other pathways,thus exacerbating the pathological manifestations of Alzheimer's *** has been widely reported that miR-146a mediates synaptic dysfunction,mitochondrial dysfunction,and neuronal death by targeting m RNAs encoding synapticrelated proteins,mitochondrial-related proteins,and membrane proteins,as well as other *** the impact on glial cells,miR-146a also exhibits differential *** one hand,it causes widespread and sustained inflammation through certain pathways,while on the other hand,it can reverse the polarization of astrocytes and microglia,alleviate neuroinflammation,and promote oligodendrocyte progenitor cell differentiation,thus maintaining the normal function of the myelin sheath and exerting a protective effect on *** this review,we provide a

关键词： Alzheimer's disease amyloid-β glial cells microRNAs miR-146a neuroinflammatory