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PARALLEL FINITE ELEMENT ANALYSIS OF HIGH FREQUENCY VIBRATIONS OF QUARTZ CRYSTAL RESONATORS ON LINUX CLUSTER

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Acta Mechanica Solida Sinica 2008年第6期21卷 549-554页

作者： Ji Wang Yu Wang Wenke Hu Wenhua Zhao Jianke Du Dejin Huang Piezoelectric Device Laboratory School of Engineering Ningbo University Ningbo 315211 China Vectron International （China） Inc. 308 Fengju Road Plant 8 Waigaoqiao Free Trade Zone Shanghai 200131 China

Quartz crystal resonators are typical piezoelectric acoustic wave devices for frequency control applications with mechanical vibration frequency at the radio-frequency （RF） range. Precise analyses of the vibration and deformation are generally required in the resonator design and improvement process. The considerations include the presence of electrodes, mountings, bias fields such as temperature, initial stresses, and acceleration. Naturally, the finite element method is the only effective tool for such a coupled problem with multi-physics nature. The main challenge is the extremely large size of resulted linear equations. For this reason, we have been employing the Mindlin plate equations to reduce the computational difficulty. In addition, we have to utilize the parallel computing techniques on Linux clusters, which are widely available for academic and industrial applications nowadays, to improve the computing efficiency. The general principle of our research is to use open source software components and public domain technology to reduce cost for developers and users on a Linux cluster. We start with a mesh generator specifically for quartz crystal resonators of rectangular and circular types, and the Mindlin plate equations are implemented for the finite element analysis. Computing techniques like parallel processing, sparse matrix handling, and the latest eigenvalue extraction package are integrated into the program. It is clear from our computation that the combination of these algorithms and methods on a cluster can meet the memory requirement and reduce computing time significantly.

关键词： plate vibration quartz resonator FEM parallel computing

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Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line

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Frontiers of Medicine 2013年第4期7卷 462-476页

作者： Douglas D.Fang Joan Cao Jitesh P.Jani Konstantinos Tsaparikos Alessandra Blasina Jill Kornmann Maruja E.Lira Jianying Wang Zuzana Jirout Justin Bingham Zhou Zhu Yin Gu Gerrit Los Zdenek Hostomsky Todd VanArsdale Oncology Research Unit PfizerInc.10777 Science Center DriveSan DiegoCA 92121USA WuXi AppTec(Shanghai)Co. Ltd.288 Fute Zhong RdWaigaoqiao Free Trade ZoneShanghai 200131China

Evaluating the effects of novel drugs on appropriate tumor models has become crucial for developing more effective therapies that target highly tumorigenic and drug-resistant cancer stem cell(CSC)*** this study,we demonstrate that a subset of cancer cells with CSC properties may be enriched into tumor spheroids under stem cell conditions from a non-small cell lung cancer cell *** these CSC-like cells with gemcitabine alone and a combination of gemcitabine and the novel CHK1 inhibitor PF-00477736 revealed that PF-00477736 enhances the anti-proliferative effect of gemcitabine against both the parental and the CSC-like cell ***,the CSC-like cells exhibited resistance to gemcitabine-induced ***,the spheroid-forming CSC-like cells may serve as a model system for understanding the mechanism underlying the drug resistance of CSCs and for guiding the development of better therapies that can inhibit tumor growth and eradicate CSCs.

关键词： drug resistance cancer stem cell checkpoint kinase 1(CHK1) PF-00477736 lung cancer tumorigenicity

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Implementing Park-Port Linking Strategies and Building an International free trade Logistics Park

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上海海事大学学报 2004年第2期25卷 112-117页

作者： YIN Nan - hua( General Manager of Shanghai waigaoqiao Logistics Center Co. , Ltd.Commander - in - chief of Project Construction Headquarters of the Shanghaiwaigaoqiao free trade Logistics Park) General Manager of Shanghai waigaoqiao Logistics Center Co. Ltd.Commander-in-chief of Project Construction Headquarters of the Shanghai Waigaoqiao Free Trade Logistics Park

Since Pudong has begun to develop and open up, The Shanghai waigaoqiao Bonded Area has seen decades of development in attracting investments from o-verseas, expanding foreign trade, promoting industrial upgrading, and providing impetus to regional economic development. With China’s entry to the WTO and the rapid progress of a global economy, the development of the modem logistics industry has altered industrial

关键词：一卯 mode free Implementing Park-Port Linking Strategies and Building an International free trade Logistics Park line

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浅谈焊接过程中三种力现象(英文)

浅谈焊接过程中三种力现象(英文)

Coevolutionary insights between promoters and transcription factors in the plant and animal kingdoms

2007中国高端SMT学术会议

作者： Rob DiMatteo Product Manager BTU International 25 Jia Tai Road Waigaoqiao Free Trade Zone.Shanghai 200131

Cooling Control Why it''''s important? Integral part of the reflow process Solder joint is not formed until solder is cooled below liquidus temperature Long term reliability influenced by coohng rate Product handling-...

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Zoological Research 2022年第5期43卷 805-812页

作者： Jing-Song Zhang Hai-Quan Wang Jie Xia Kun Sha Shu-Tao He Hao Dai Xiao-Hu Hao Yi-Wei Zhou Qiu Wang Ke-Ke Ding Zhang-Lei Ju Wen Wang Luo-Nan Chen Key Laboratory of Systems Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesShanghai 200031China Department of General Surgery Shanghai General Hospital of Shanghai Jiao Tong University School of MedicineShanghai 200080China College of Information Engineering Zhejiang University of TechnologyHangzhouZhejiang 310023China Naval Healthcare Information Center Faculty of Military Health ServicesNaval Medical UniversityShanghai 200433China Bioinformatics Core of Excellence Department GenScript Biotech CorporationNanjingJiangsu 211110China waigaoqiao free trade zone Wuxi BiologicsShanghai 200131China Department of Cardiology Tongji HospitalTongji University School of MedicineShanghai 200065China School of Ecology and Environment Northwestern Polytechnical UniversityXi’anShaanxi 710072China State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China Key Laboratory of Systems Health Science of Zhejiang Province School of Life ScienceHangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesChinese Academy of SciencesHangzhouZhejiang 310024China Guangdong Institute of Intelligence Science and Technology ZhuhaiGuangdong 519031China

The divergence and continuous evolution of plants and animals contribute to ecological *** and transcription factors(TFs) are key determinants of gene regulation and transcription ***,theevolutionary trajectories and relationships of promoters and TFs are still poorly understood. Here, we conducted extensive analysis of large-scale multi-omics sequences in 420 animal species and 223 plant species spanning nearly a billion years of evolutionary history. Results showed that promoter GC-contentandTFisoelectricpoints,as features/signatures that accompany long biological evolution, exhibited increasing growth in animal cells but a decreasing trend in plant cells. Furthermore, the evolutionary trajectories of promoter and TF signatures in the animal kingdom provided further evidence that Mammalia as well as Aves evolved directly from the ancestor Reptilia. The strong correlation between promoter and TF signatures indicates that promoters and TFs formed antagonistic coevolution in the animal kingdom, but mutualistic coevolution in the plant kingdom. The distinct coevolutionary patterns potentially drive the plant-animal divergence, divergent evolution and ecological diversity.

关键词： Molecularevolution Coevolution Promoter Transcription factor Plant-animal divergence

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