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China medical Abstracts(Internal medicine) 2024年第1期41卷 46-46页

作者：张奕秉 Dept Gastroenterol Wenzhou Centr HospDingli Clin CollWenzhou Med UnivWenzhou 325000

Objective To investigate the efficacy of Modified Banxia Xiexin Decoction on patients with functional dyspepsia (FD) and its impact on gastric *** From June 2021 to December 2022,at the Department of Gastroenterology,wenzhou Central Hospital,a total of 56 patients with FD who met the diagnostic criteria of RomeⅣwere prospectively enrolled.

关键词： patients dyspepsia gastric

Modified Guipi decoction in treatment of language development disorders in cbIC type methylmalonic aciduria children with Xin-Pi deficiency syndrome:a randomized controlled trial

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China medical Abstracts(Internal medicine) 2024年第1期41卷 15-16页

作者：李甜馨 Pediatr med coll Henan CM UnivZhengzhou 450000

Objective To observe the clinical efficacy of modified Guipi Decoction (MGD) in treatment of language development disorders in cblC type methylmalonic aciduria (MMA) children with Xin-Pi deficiency *** Totally 61 language development disorders in cblC type MMA children with XinPi deficiency were randomly assigned to the experimental group(31 cases) and the control group(30cases).

关键词： language children assigned

Effects of electroacupuncture on repairing neurological damage following ischemic stroke based on miR-381-mediated SDF-1/CXCR4 signaling pathway

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China medical Abstracts(Internal medicine) 2024年第2期41卷 71-72页

作者：宋雪梅 Rehab med coll Henan TCM UnivZhengzhou 450046

Objective To investigate theeffects of electroacupuncture(EA)on the miR-381,leucine-rich repeat C4 protein(LRRC4),and downstream stromal cell-derived factor-1(SDF-1)/CXC chemokine receptor 4(CXCR4)signaling pathway in rat model of ischemic stroke,and to explore the mechanism by which EA improves neurological damage following ischemic *** Among 50 SPF male SD rats,10 rats were randomly selected into a sham surgery group,and the remaining rats were used to establish the middle cerebral artery occlusion(MCAO)*** 30 successfully modeled rats were randomly divided into a model group,an EA group,and an agonist group,with 10 rats in each group.

关键词： damage CXCR4 cerebral

Untargeted metabolomics methods to study the pattern of metabolites in the serum of brucellosis patientS

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China medical Abstracts(Internal medicine) 2024年第2期41卷 87-88页

作者：鲁婧屹 Sch Public Health Baotou Med CollBaotou 014000

Objective To study the changes in serum small molecule metabolites after brucella infection in humans using untargeted metabolomics methods,and screening representative *** A total of 109 serum samples collected from January 2019 to December 2021 at the Brucellosis Clinic of the Baotou Center for Disease Control and Prevention were divided into acute phase group(n=40),chronic phase group(n=35)of brucellosis,and healthy group(n=34)based on clinical ***-high performance liquid chromatography quadrupole time-of-flight mass spectrometry technology was used to test serum samples and screen for differential *** operating characteristic curve was used to evaluate the predictive ability of differential metabolites for *** pathways were screened using Kyoto Encyclopedia of Genes and Genomes(KECG)pathway toidentifyymetabolic pathways significantly *** A total of 17 differential metabolites were screened between the acute phase group and the healthy group,and 12 differential metabolites were screened between the chronic phase group and the healthy group.

关键词： targeted acute pattern

Effect of Aconiti Lateralis Radix Praeparata combined with Cinnamomi Cortex on intestinal motility and expression of SCF and c-Kit in slow transit constipation rats with Yang deficiency syndrome

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China medical Abstracts(Internal medicine) 2024年第1期41卷 12-13页

作者：张远哲 Basic med coll Guizhou TCM UnivGuiyang 550025

Objective To investigate the effects of the Aconiti lateralis Radix Praeparata-Cinnamomi Cortex (ALRP-CC)compound on the expression of intestinal neurotransmitters and stem cell factor (SCF),c-kitprotooncogeneprotein (c-Kit) in slow transit constipation (STC) rats with Yang deficiency syndrome,and to explore its mechanism of action for improving intestinal motility.

关键词： Radix motility rats

LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway

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China medical Abstracts(Internal medicine) 2024年第2期41卷 104-105页

作者：陶绍能 Dept Nucl med 1st Affil HospWannan Med CollWuhu 241000

Objective To investigate the effects of lncRNA SNHG11 on proliferation,migration,invasion and apoptosis of colorectal cancer cancer cells and possible *** qRT-PCR was performed to detect the expression level of lncRNA... 详细信息

关键词： invasion colorectal cancer

Laparoscopic vs open left hepatectomy for hepatolithiasis

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World Journal of Gastroenterology 2010年第22期16卷 2818-2823页

作者： Tu, Jin-Fu Jiang, Fei-Zhao Zhu, Heng-Liang Hu, Ru-Ying Zhang, Wei-Jian Zhou, Zhen-Xu wenzhou med coll Affiliated Hosp 1 Dept Laparoscop Surg Wenzhou 325000 Zhejiang Peoples R China

AIM: To explore the feasibility and therapeutic effect of total laparoscopic left hepatectomy (LLH) for hepatolithiasis. METHODS: From June 2006 to October 2009, 61 consecutive patients with hepatolithiasis who met the inclusion criteria for LLH were treated in our institute. Of the 61 patients with hepatolithiasis, 28 underwent LLH (LLH group) and 33 underwent open left hepatectomy (OLH group). Clinical data including operation time, intraoperative blood loss, postoperative complication rate, postoperative hospital stay time, stone clearance and recurrence rate were retrospectively analyzed and compared between the two groups. RESULTS: LLH was successfully performed in 28 patients. The operation time of LLH group was longer than that of OLH group (158 ± 43 min vs 132 ± 39 min, P mediate rate 17.9% vs 12.1% and final rate 0% vs 0%) between the twogroups. No perioperative death occurred in either group. Fifty-seven patients (93.4%) were followed up for 2-40 mo (mean 17 mo), including 27 in LLH group and 30 in OLH group. Stone recurrence occurred in 1 patient of each group. CONCLUSION: LLH for hepatolithiasis is feasible and safe in selected patients with an equal therapeutic effect to that of traditional open hepatectomy.

关键词： Hepatolithiasis Laparoscopy Hepatectomy Complication Therapeutic effect

Study on mechanism of Shenqu Zhuyu decoction in improving varicocele rats spermatogenesis based on PINK1/Parkin mediated mitophagy and apoptosis

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China medical Abstracts(Internal medicine) 2024年第2期41卷 75-76页

作者：张芳 Dept Centr Lab 5th Clin Med CollShanxi Med UnivTaiyuan 030012

Objective To observe the effect of the Shenqu Zhuyu Decoction(SZD)on varicocele(VC)rats mitophagy and apoptosis in left testis based on PTENinduced putative kinase 1(PINK1)/E3 ubiquitin protein ligase(Parkin)signaling pathway,and to explore its *** Totally 36 male SD rats were randomly divided into sham operation group,model group and SZD group,12 rats in each *** rats model was established by partial ligation of the left renal vein in model group and SZD *** 48th day after successful molding,the rats in SZD group were treated with SZD(0.7 g/100 g)by gavage,and rats in sham operation group and model group were given the equal volume of normal saline by gavage,twice a day for 60 days.

关键词： PINK1 Parkin apoptosis

Surgically treated primary malignant tumor of small bowel:A clinical analysis

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World Journal of Gastroenterology 2010年第12期16卷 1527-1532页

作者： Han, Shao-Liang Cheng, Jun Zhou, Hong-Zhong Guo, Sheng-Cong Jia, Zeng-Rong Wang, Peng-Fei wenzhou med coll Affiliated Hosp 1 Dept Gen Surg Wenzhou 325000 Zhejiang Prov Peoples R China

AIM:To evaluate the clinical presentation,treatment and survival of patients with primary malignant tumor of small bowel(PMTSB).METHODS:Clinicopathologic data about 141 surgically treated PMTSB patients(91 males and 50 females) at the median age of 53.5 years(range 23-79 years) were retrospectively ***:The most common initial clinical features of the patients were intermittent abdominal discomfort or vague abdominal pain(67.4%),abdominal mass(31.2%),bowel obstruction(24.1%),hemotochezia(21.3%),jaundice(16.3%),fever(14.2%),coexistence of bowel perforation and peritonitis(5.7%),coexistence of gastrointestinal bleeding and shock(5.0%),and intraabdominal bleeding(1.4%).Ileum was the most common site of tumor(44.7%),followed by jejunum(30.5%)and duodenum(24.8%).PMTSB had a nonspecific clinical *** bowel resection(n=81)was the most common surgical procedure,followed by right hemicolectomy(n=15),pancreaticoduodenectomy(n=10),and others(n=19).Twenty-seven adenocarcinoma patients and 13 malignant lymphoma patients received adjuvant chemotherapy with 5-fluorouracil and cyclophosphamide,adriamycin,vincristine and prednisone,*** about 120 patients was obtained during the *** median survival time of PMTSB patients was 20.3 *** 1-,3-and 5-year survival rate was 75.0%(90/120),40.0%(48/120)and 20.8%(25/120),*** was found in 73.7%(42/57),21.1%(12/57)and 15.8%(9/57)of the patients,*** stromal tumor was observed in 80.0%(20/25),72.0%(18/25)and 36.0%(9/25)of the patients,*** was detected in 100.0%(15/15),80.0%(12/15)and 46.7%(7/15)of the patients,*** lymphoma was demonstrated in 69.2%(9/13),30.8%(4/13)and 0%(0/13)of the patients,***:En bloc resection is the principal therapy for most PMTSB and chemotherapy is the important treatment modality for malignant lymphoma and other malignant tumors of small bowel which ca

关键词： Small bowel Malignant tumor Diagnosis Surgical treatment Chemotherapy

Genetic susceptibility of PLCEI gene polymorphism and primary nephrotic syndrome in Guangxi Zhuang children

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China medical Abstracts(Internal medicine) 2024年第1期41卷 52-53页

作者：杨三菊 Dept Pediatr Affil HospYoujiang Ethnic Med CollBaise 533000

Objective To investigate the relationship between single nucleotide polymorphic (SNP) loci of PLCE1 gene and primary nephrotic syndrome (PNS) and its response to glucocorticoid therapy in Guangxi Zhuang children.

关键词： nephrotic glucocorticoid Zhuang