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Laser processing effects on Ti−45Nb alloy surface,corrosive and biocompatible properties

Transactions of Nonferrous Metals Society of China 2024年第8期34卷 2533-2551页

作者： I.CVIJOVIĆ-ALAGIĆ S.LAKETIĆ M.MOMČILOVIĆ J.CIGANOVIĆ Đ.VELJOVIĆ J.BAJAT V.KOJIĆ M.RAKIN vinča institute of nuclear sciences-national institute of thеrepublic of serbia University of BelgradeP.O.Box 52211001 BelgradeSerbia Faculty of Technology and Metallurgy University of BelgradeKarnegijeva 411120 BelgradeSerbia Oncology institute of Vojvodina Faculty of MedicineUniversity of Novi SadPut Dr Goldmana 421204 Sremska KamenicaSerbia

the Ti−45Nb(wt.%)alloy properties were investigated in relation to its potential biomedical *** surface modification was utilized to improve its performance in biological *** a result of the laser treatment,(Ti,Nb)O scale was formed and various morphological features appeared on the alloy *** electrochemical behavior of Ti−45Nb alloy in simulated body conditions was evaluated and showed that the alloy was highly resistant to corrosion deterioration regardless of additional laser surface modification ***,the improved corrosion resistance after laser treatment was evident(the corrosion current density of the alloy before laser irradiation was 2.84×10^(−8)A/cm2,while that after laser treatment with 5 mJ was 0.65×10^(−8)A/cm2)and ascribed to the rapid formation of a complex and passivating bi-modal surface oxide *** cytotoxicity and effects of the Ti−45Nb alloy laser surface modification on the MRC-5 cell viability,morphology,and proliferation were also *** Ti−45Nb alloy showed no cytotoxic ***,cells showed improved viability and adherence to the alloy surface after the laser irradiation *** highest average cell viability of 115.37%was attained for the alloy laser-irradiated with 15 *** showed that the laser surface modification can be successfully utilized to significantly improve alloy performance in a biological environment.

关键词： Ti−45Nb alloy laser surface scanning electrochemical properties biocompatibility cell morphology

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Impact of Microstructural and Surface Modifications on the Ti-45Nb Alloy’s Response to Bio-Environment

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Acta Metallurgica Sinica(English Letters) 2024年第7期37卷 1215-1230页

作者： Ivana Cvijović-Alagić Slađana Laketić MilošMomčilović Jovan Ciganović Jelena Bajat Vesna Kojić vinča institute of nuclear sciences-national institute of the republic of serbia University of BelgradeMike Petrovića Alasa 12-1411000BelgradeSerbia Faculty of Technology and Metallurgy University of BelgradeKarnegijeva 411000BelgradeSerbia Oncology institute of Vojvodina Faculty of MedicineUniversity of Novi SadPut Doktora Goldmana 4Sremska Kamenica21204Sremska KamenicaSerbia

the Ti-45Nb (mass%) alloy’s corrosive and biocompatible response in simulated physiological conditions was investigated before and after its additional high-pressure torsion (HPT) and laser irradiation processing. the grain size reduction from 2.76 µm to ~ 200 nm and the appearance of laser-induced morphologically altered and highly oxidized surface led to the significant improvement of alloy corrosion resistance and cell–implant interaction. Moreover, an additional increase of the laser pulse energy from 5 to 15 mJ during the alloy irradiation in the air led to an increase in the surface oxygen content from 13.64 to 23.89% accompanied by an increase of excellent cell viability from 127.18 to 134.42%. As a result of the controlled alloy microstructural and surface modifications, the formation of protective bi-modal mixed Ti- and Nb-oxide external scale was enabled. the presence of this surface oxide scale enhanced the alloy’s resistance to corrosion deterioration and simultaneously boosted cell viability and proliferation.

关键词： Ti-45Nb alloy High-pressure torsion Laser surface scanning Corrosion resistance Biocompatible properties

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Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease

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Neural Regeneration Research 2024年第8期19卷 1641-1642页

作者： Sanja Ivkovic Djuro Koruga Department of Molecular Biology and Endocrinology “VINCA”Institute of Nuclear Sciences-National Institute of Republic of SerbiaUniversity of BelgradeBeogradSrbija TFT Nano Center BelgradeSerbia

Fullerenes:the extensive development of nanoscience that has marked this century continues to evolve,producing new materials,structures,and devices for the treatments of diverse *** are a family of nanoparticles with great applicative promise due to their small size(approximately 1 nm in diameter),structure,and capacity to cross biological barriers.

关键词： treatment evolve size

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Physiological strategies in wild rodents:immune defenses of commensal rats

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Integrative Zoology 2024年第3期19卷 350-370页

作者： Ivana MIRKOV Dina TUCOVIC Jelena KULAS Anastasija MALESEVIC Dragan KATARANOVSKI Milena KATARANOVSKI Aleksandra POPOV ALEKSANDROV Immunotoxicology Group Department of EcologyInstitute for Biological Research“Sinisa Stankovic”—National Institute of Republic of SerbiaUniversity of BelgradeBelgradeSerbia

the importance of issues associated with urban/commensal rats and mice(property damage,management costs,and health risks)press upon research on these *** the demography of commensal rodents is mostly studied,the need for understanding factors influencing their natural morbidity/mortality is also *** this respect,more attention is expected to be paid to immunity,the physiological mechanism of defense against host survival threats(pathogens,parasites,diseases).Commensal rats and mice carry numerous pathogens that evoke diverse immune *** state of immunity in commensal house mice is studied in great detail,owing to the use of laboratory strains in biomedical *** commensal rats are,compared to mice,carriers of more zoonotic agents,rats’immunity is studied mainly in that *** of these zoonotic agents cause chronic,asymptomatic infections,which justified studies of immunological mechanisms of pathogen tolerance versus clearance regulation in *** of some infections in specific tissues/organs pressed upon analysis of local/regional immune responses and/or immunopathology.A survey of immunological activity/responses in commensal rats is given in this review,with mention of existing data in commensal *** should throw some light on the factors relevant to their morbidity and lifespan,supplementing the knowledge of commensal rodent ecology.

关键词： commensal rats and mice immunopathology infection inflammation tolerance

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In vivo femtosecond laser nanosurgery of the cell wall enabling patch-clamp measurements on filamentous fungi

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Microsystems & Nanoengineering 2024年第2期10卷 251-267页

作者： Tanja Pajić Katarina Stevanović Nataša V.Todorović Aleksandar J.Krmpot Miroslav Živić Svetlana Savić-Šević Steva M.Lević Marina Stanić Dejan Pantelić Brana Jelenković Mihailo D.Rabasović institute of Physiology and Biochemistry“Ivan Djaja” Faculty of BiologyUniversity of BelgradeStudentski trg 1611158BelgradeSerbia institute for Biological Research“Siniša Stanković” University of BelgradeNational Institute of the Republic of SerbiaBulevar Despota Stefana 14211000BelgradeSerbia institute of Physics Belgrade University of BelgradeNational Institute of the Republic of SerbiaPregrevica 11811080BelgradeSerbia University of Belgrade Faculty of AgricultureNemanjina Street 611080BelgradeSerbia institute for Multidisciplinary Research University of BelgradeKneza Višeslava 111030BelgradeSerbia

Studying the membrane physiology of filamentous fungi is key to understanding their interactions with the environment and crucial for developing new therapeutic strategies for disease-causing ***,their plasma membrane has been inaccessible for a micron-sized patch-clamp pipette for pA current recordings due to the rigid chitinous cell ***,we report the first femtosecond IR laser nanosurgery of the cell wall of the filamentous fungi,which enabled patch-clamp measurements on protoplasts released from hyphae.A reproducible and highly precise(diffraction-limited,submicron resolution)method for obtaining viable released protoplasts was *** release from the nanosurgery-generated incisions in the cell wall was achieved from different regions of the *** plasma membrane of the obtained protoplasts formed tight and high-resistance(GΩ)contacts with the recording *** entire nanosurgical procedure followed by the patch-clamp technique could be completed in less than 1 *** to previous studies using heterologously expressed channels,this technique provides the opportunity to identify new ionic currents and to study the properties of the ion channels in the protoplasts of filamentous fungi in their native environment.

关键词： patch recording laser

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Measurement of yields and angular distributions ofγ-quanta from the interaction of 14.1 MeV neutrons with oxygen,phosphorus,and sulfur

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Chinese Physics C 2024年第3期48卷 79-92页

作者： D.N.Grozdanov N.A.Fedorov S.B.Dabylova Yu.N.Kopatch I.N.Ruskov V.R.Skoy T.Yu.Tretyakova C.Hramco P.I.Kharlamov G.V.Pampushik P.G.Filonchik A.V.Andreev Joint institute for nuclear Research(JINR) DubnaRussia institute for nuclear Research and nuclear Energy Bulgarian Academy of SciencesSofiaBulgaria Faculty of Physics Lomonosov Moscow State UniversityMoscowRussia L.N.Gumilyov Eurasian national University AstanaKazakhstan Skobeltsyn institute of nuclear Physics Moscow State UniversityMoscowRussia institute of Chemistry of Moldova ChisinauRepublic of Moldova Moscow institute of Physics and Technology MoscowRussia

A study of the inelastic scattering of neutrons with an energy of 14.1 MeV on the nuclei of oxygen,phosphorus,and sulfur was performed at the TANGRA facility at JINR(Dubna).the experiment aimed to refine existing data and obtain new data on the yields and angular distributions ofγ-quanta emitted by the studied nuclei due to neutron-induced nuclear reactions using the tagged neutron *** types of detector systems were used to registerγ-***γ-ray yields were measured using a high-purity germanium(HPGe)*** angular distributions ofγ-rays were obtained using a system of 18 scintillation detectors based on bismuth germanite Bi_(4)Ge_(3)O_(12)(BGO)located around the *** performed experiments measured the yields of two transitions for the reaction of tagged neutrons with 16O,nine transitions for the reaction with ^(31)P,and nine transitions for the reaction with ^(32)S for the first *** angular anisotropy of theγ-radiation accompanying the inelastic scattering of neutrons with an energy of 14.1 MeV on ^(31)P nuclei was also measured for the first time.

关键词： tagged neutron method yields of gamma-quanta high-resolution gamma-spectrometry neutron-nuclear reactions neutron scattering

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Functional Optical Fiber Sensors Detecting Imperceptible Physical/Chemical Changes for Smart Batteries

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Nano-Micro Letters 2024年第8期16卷 268-308页

作者： Yiding Li Li Wang Youzhi Song Wenwei Wang Cheng Lin Xiangming He institute of nuclear and New Energy Technology Tsinghua UniversityBeijing 100084People’s Republic of China national Engineering Research Center of Electric Vehicles Beijing Institute of Technology(BIT)Beijing 100081People’s Republic of China Shenzhen Automotive Research institute of BIT(Shenzhen Research institute of national Engineering Research Center of Electric Vehicles) Shenzhen 518118People’s Republic of China

the battery technology progress has been a contradictory process in which performance improvement and hidden risks *** the battery is still a“black box”,thus requiring a deep understanding of its internal *** battery should“sense its internal physical/chemical conditions”,which puts strict requirements on embedded sensing *** paper summarizes the application of advanced optical fiber sensors in lithium-ion batteries and energy storage technologies that may be mass deployed,focuses on the insights of advanced optical fiber sensors into the processes of one-dimensional nano-micro-level battery material structural phase transition,electrolyte degradation,electrode-electrolyte interface dynamics to three-dimensional macro-safety *** paper contributes to understanding how to use optical fiber sensors to achieve“real”and“embedded”*** the inherent advantages of the advanced optical fiber sensor,it helps clarify the battery internal state and reaction mechanism,aiding in the establishment of more detailed *** advancements can promote the development of smart batteries,with significant importance lying in essentially promoting the improvement of system ***,with the help of smart batteries in the future,the importance of consistency can be weakened or even *** application of advanced optical fiber sensors helps comprehensively improve the battery quality,reliability,and life.

关键词： Smart battery Advanced embedded optical fiber sensor Battery internal physical/chemical state Quality-reliability-life characteristic

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Multi-layer phenomena in petawatt laser-driven acceleration of heavy ions

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Plasma Science and Technology 2024年第2期26卷 70-76页

作者：苏琬晴曹喜光马春旺王玉廷张国强 College of Physics Henan Normal UniversityXinxiang 453007People's Republic of China Shanghai Advanced Research institute Chinese Academy of SciencesShanghai 201210People's Republic of China Shanghai institute of Applied Physics Chinese Academy of SciencesShanghai 201800People's Republic of China University of Chinese Academy of sciences Bejing 100049People's Republic of China institute of nuclear Science and Technology Henan Academy of ScienceZhengzhou 450046People's Republic of China

Laser-accelerated high-flux-intensity heavy-ion beams are important for new types of accelerators.A particle-in-cell program(Smilei) is employed to simulate the entire process of Station of Extreme Light(SEL) 100 PW laser-accelerated heavy particles using different nanoscale short targets with a thickness of 100 nm Cr, Fe, Ag, Ta, Au, Pb, th and U, as well as 200 nm thick Al and Ca. An obvious stratification is observed in the simulation. the layering phenomenon is a hybrid acceleration mechanism reflecting target normal sheath acceleration and radiation pressure acceleration, and this phenomenon is understood from the simulated energy spectrum,ionization and spatial electric field distribution. According to the stratification, it is suggested that high-quality heavy-ion beams could be expected for fusion reactions to synthesize superheavy nuclei. Two plasma clusters in the stratification are observed simultaneously, which suggest new techniques for plasma experiments as well as thinner metal targets in the precision machining process.

关键词： petawatt laser-plasma interaction laser-driven heavy-ion accelerator for synthesizing superheavy nuclei particle-in-cell multi-layer phenomena target fabrication

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Design of a 3D-printed liquid lithium divertor target plate and its interaction with high-density plasma

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Plasma Science and Technology 2024年第8期26卷 112-120页

作者：苑聪聪叶宗标刘建星郭恒鑫彭怡超廖加术陈波陈建军王宏彬韦建军张秀杰芶富均 institute of nuclear Science and Technology Sichuan UniversityChengdu 610064People’s Republic of China institute of Atomic and Molecular Physics Sichuan UniversityChengdu 610064People’s Republic of China Southwestern institute of Physics Chengdu 610064People’s Republic of China

A liquid Li divertor is a promising alternative for future fusion *** this work a new divertor model is proposed,which is processed by 3D-printing technology to accurately control the size of the internal capillary *** a steady-state heat load of 10 MW m^(-2),the thermal stress of the tungsten target is within the bearing range of tungsten by finite-element *** order to evaluate the wicking ability of the capillary structure,the wicking process at 600℃ was simulated by *** result was identical to that of the corresponding *** 1 s,liquid lithium was wicked to the target surface by the capillary structure of the target and quickly spread on the target *** the wicking process,the average wicking mass rate of lithium should reach 0.062 g s^(-1),which could even supplement the evaporation requirement of liquid lithium under an environment>950℃.Irradiation experiments under different plasma discharge currents were carried out in a linear plasma device(SCU-PSI),and the evolution of the vapor cloud during plasma irradiation was *** was found that the target temperature tends to plateau despite the gradually increased input current,indicating that the vapor shielding effect is gradually *** irradiation experiment also confirmed that the 3D-printed tungsten structure has better heat consumption performance than a tungsten mesh structure or multichannel *** results reveal the application potential and feasibility of a 3D-printed porous capillary structure in plasma-facing components and provide a reference for further liquid-solid combined target designs.

关键词： fusion divertor 3D-printing tungsten lithium liquid metal

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A dual-route optical emission spectroscopy diagnostic with wide spectral range and high wavelength resolution on HL-2A tokamak

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Plasma Science and Technology 2024年第3期26卷 25-30页

作者：陈越高继昆龙婷聂林高金明马尧黄渊田文静刘延民朱晓东庄革钟武律许敏 School of Physical sciences School of Nuclear Sciences and TechnologyUniversity of Science and Technology of ChinaHefei 230026People's Republic of China Southwestern institute of Physics Chengdu 610041People's Republic of China Tsinghua University Beijing 100084People's Republic of China

A dual-route optical emission spectroscopy(D-OES)diagnostic is newly developed to monitor the optical emission from the X-point plasma region on the HL-2 A *** diagnostic is composed of an imaging system,a beam-splitting system for dual-route measurements,fiber bundles,a spectrometer system,and a control and acquisition *** route is used to obtain wide-spectral-range spectra,and the other route is used to acquire high-wavelengthresolution line *** spectral resolution of the wide-range spectrometers is 0.8 nm with a coverage of 800 nm(@200-1000 nm).the spectral resolution of the high-resolution spectrometer is 0.01 nm with a coverage of 6 nm(@200-660 nm).the spatial resolution of each route of D-OES is about 4 cm with 11 *** temporal resolution is 16 ms at maximum in the single-channel ***-range spectra(containing Balmer series and a Fulcher band)and highly resolved Ha line shapes are obtained by D-OES in the hydrogen glow discharge in the lab.D-OES measurements are carried out in the high-density deuterium experiments of *** electron density n_(e)and deuterium temperature T_(D) in the X-point multifaceted asymmetric radiation from the edge(MARFE)region are derived simultaneously by fitting the measured D_(a) *** density n_(e)is observed to increase from~8.7×10^(18)m^(-3)to~7.8×10^(19)m^(-3),and the temperature T_(D)drops from~14.4 eV to~2.3 eV after the onset of MARFE in the discharge#38260.

关键词： optical emission spectroscopy Balmer series tokamak

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