检索结果-南通市图书馆

Trends in the rates of hospitalizations for acute stroke among patients over 90 years of age with atrial fibrillation in the United States： from 2005 to 2014

引用

Journal of Geriatric Cardiology 2017年第9期14卷 547-552页

作者： Ghanshyam PS Shantha Amgad Mentias Musab Alqasrawi Abdul Qazi Chakradhari Inampudi Kongkiat Chaikriangkrai Abhishek Deshmuk Steven Bailin Michael Giudici Alexander Mazur Division of Cardiovascular Medicine University of Iowa Hospitals and Clinics lowa City lowa USA Mayo Clinic Rochester MN USA

Background Acute stroke （AS） rates in patients over 90 years of age （very elderly） with atrial fibrillation （AF） in the United States（US） are not known. We assessed trends in hospitalizations for AS among very elderly with AF in the US from 2005 to 2014. Methods Weused the nationwide inpatient sample （NIS） from the USA; 2005-2014. AF and AS diagnoses were abstracted using international classifica-tion of diseases, 9th Revision, clinical modification （ICD-9-CM） codes. Results From 2005 to 2014, 3,606,073 hospitalizations of veryelderly with AF were reported. Of these, 188,948 hospitalizations （141,822 hospitalizations in women and 47,126 hospitalizations in men）had AS as the primary diagnosis. Age adjusted AS hospitalizations increased in the total cohort （3217/million in 2005 to 3871/million in2014）, in women （3540/million in 2005 to 4487/million in 2014） and in men （2490/million in 2005 to 3173/million in 2014）（P 〈 0.001）.Anticoagnlation rates increased in women （8% in 2005 to 19.9% in 2014） and in men （8.9% in 2005 to 21.6% in 2014）. AS rates, thoughnumerically lower than the total cohort, showed an increasing trend in anticoagnlated patients as well （all anticoagulated patients： 212/millionin 2005 to 513/million in 2014; anticoagulated women： 224/million in 2005 to 529/million in 2014, anticoagnlated men： 184/million in 2005to 518/million in 2014）. Conclusions There is an increasing trend in AS hospitalizations among nonagenarians with AF in the US despiteimproving utilization of anticoagulants in this patient population. The etiologies driving this alarming trend are unclear and require fur-ther study.

关键词： Anticoagulation Atrial fibrillation Nonagenarian Stroke

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Micro-recanalization in a biodegradable graft for reconstruction of the vas deferens is enhanced by sildenafil citrate

引用

Asian Journal of Andrology 2010年第6期12卷 814-818页

作者： Peter A. Holoch Surya K. Mallapragada Carlos A. Ariza Thomas S. Griffith Barry R. DeYoung Moshe Wald DePartment of Urology University of lowa lowa City 1A 52242 USA Department of Chemical Engineering Iowa State University Ames IA 50011 USA Department of Pathology University of Iowa Iowa City IA 52242 USA

This study investigated the effect of sildenafil citrate on micro-recanalization and neovascularization, which were previously demonstrated in a rat model using biodegradable grafts （BGs） for vas deferens reconstruction. A total of 24 male rats underwent bilateral vasectomy with removal of a 0.5-cm vasal segment and were randomly assigned to four groups. Groups 1 and 2 underwent immediate vasovasostomy. Groups 3 and 4 underwent interposition of a 0.5-cm BG in the vasal gap. Groups 1 and 3 were given 5 mg kg-1 day-1 oral sildenafil. Other groups were given placebo. Rats were housed with females 12 weeks postoperatively. Reconstructed vasal segments were harvested 16 weeks postoperatively and analyzed histologically. Fluid from the distal vasal stump was analyzed for motile sperm. Urine samples obtained 16 weeks postoperatively were analyzed for cGMP levels. cGMP levels in rats treated with sildenafil were signifcantly higher than in control rats. No pregnancies were sired by grafted groups. In all, 5/6 rats in group 1 and 3/6 rats in group 2 sired litters. No motile sperm were noted in the vasal fluid of the grafted groups. Motile sperm were noted in all rats in group 1 and in 5/6 rats in group 2. In addition, 29 and 4 microcanals were detected in the sildenafil and placebo groups, respectively （P = 0.023）. No microcanal exceeded 3 mm in length. An average of 12 and 28 blood vessels per graft were noted in the placebo and sildenafil groups, respectively （P 〈 0.0001）. In conclusion, sildenafil enhances micro-recanalization and neovascularization in BG used for vas deferens reconstruction, but does not increase the microcanal length after 16 weeks.

关键词： graft infertility male sildenafil citrate vas deferens vasectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Analytical methods for investigating in vivo fate of nanoliposomes:A review

引用

Journal of Pharmaceutical Analysis 2018年第4期8卷 219-225页

作者： Chong Su Yingze Liu Yang He Jingkai Gu College of Life Science Jilin University Department of Pharmaceutical Sciences and Experimental Therapeutics College of Pharmacy University of lowa

Nanoliposomes are considered to be the most successful nanoparticle drug delivery system, but their fate in vivo has not been fully understood due to lack of reliable bioanalytical methods, which seriously limits the development of liposomal drugs. Hence, an overview of currently used bioanalytical methods is imperative to lay the groundwork for the need of developing a bioanalytical method for liposome measurements in vivo. Currently, major analytical methods for nanoliposomes measurement in vivo include fluorescence labeling, radiolabeling, magnetic resonance imaging（MRI）, mass spectrometry and computed tomography. In this review, these bioanalytical methods are summarized, and the advantages and disadvantages of each are discussed. We provide insights into the applicability and limitations of these analytical methods in the application of nanoliposomes measurement in vivo, and highlight the recent development of instrumental analysis techniques. The review is devoted to providing a comprehensive overview of the investigation of nanoliposomes design and associated fate in vivo, promoting the development of bioanalytical techniques for nanoliposomes measurement, and understanding the pharmacokinetic behavior, effectiveness and potential toxicity of nanoliposomes in vivo.

关键词： Liposomes Analytical methods In vivo fate Liposomal drug

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of Topography and Land Use Change on Gully Development in Typical Mollisol Region of Northeast China

引用

Chinese Geographical Science 2016年第6期26卷 779-788页

作者： LI Hao Richard M CRUSE LIU Xiaobing ZHANG Xingyi Key Laboratory of Mollisols Agroecology Northeast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081China university of Chinese Academy of Sciences Beijing 100049China Department of Agronomy lowa State UniversityAmes500011 lowaUSA

Due to high intensity agricultural exploitation since the middle of the 20 th century, farmland gullies have become a pervasive form of water erosion in Northeast China. Yet few researches are concentrated on how topography and land use affect long-term gully development in this region. In this study, gully distribution in a village with an area of 24.2 km^2 in the central Mollisols area of Northeast China in different times were compared by Aerial photography(1968), Quickbird image(2009) and field survey, and factors affecting gully development including land use and topography were analyzed. The results showed that the total gully number decreased from 104 to 69, while occupying area rose from 34.8 ha to 78.4 ha from 1968 to 2009. Fundamental gully distribution had been formed by 1968 as most of 2009′s gullies were evolved from 1968′s gullies′ merge and width expansion process, and new gullies those initiated after 1968 occupied only 7% of total gully area in 2009. Gully area increasing ratio in grassland was the highest and that in forestland was the lowest. The threshold catchment area between simple and complex gully development was around 15 ha to 25 ha. This threshold value sets apart catchment areas that will develop simple or complex gullies in areas with similar environmental conditions. Gully control measurements were urgent because if appropriate gully control implements would not be applied, present gully erosion crisis could be doubled within 50 years.

关键词： gully erosion land use topographic threshold Mollisols Northeast China

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Studies on Antimicrobial Resistance Transfer In vitro and Existent Selectivity of Avian Antimicrobial-Resistant Enterobacteriaccae In vivo

引用

Agricultural Sciences in China 2008年第5期7卷 636-640页

作者： SONG Li NING Yi-bao ZHANG Qi-jing YANG Cheng-hua GAO Guang HAN Jian-feng China institute of Veterinary Drug Control Beijing 100081 P.R.China College of Veterinary Medicine lowa State University lowa 50011-1250 USA

Increasing antimicrobial resistance （AR） has become a severe problem of public health in the world, whereas control of the AR of bacteria will be based on investigation of the AR mechanism. Furthermore, understanding the existent selectivity of AR organisms from animals can prevent the emergence and diffusion of AR effectively. PCR amplifications of gyrA and parC genes have been performed for detecting fluoroquinolones-resistance （FR） genes. A conjugational transfer test has been carried out using a donor which is resistant to tetracycline （TE）, ampicillin （AMP）, sulfamethoxazole-trimethoprim （SXT）, and a recipient which is sensitive to TE, AMP, and SXT. The AR strains have been passed 20 passages. Two groups of chicken inoculated multi-AR Escherichia coli （E. coli） and multi-AR Salmonella, respectively, are mix-fed. The result shows that amino acid codons of Ser-83 and Asp-87 are mutations from gyrA and there are no mutations from parC genes in all the FR strains. Resistance to TE, AM, and SXT can transfer among E. coli and the conjugal transfer frequency of TE is 3×10^-7. AR can inherit in 20 passages at least. The multi-AR E. coli and Salmonella can be isolated from all chickens three days after inoculation but CIP-resistant strains decrease during the time run out and disappear at 23 days after inoculation. The results indicate that the mutations of gene gyrA are correlative with the FR phenotype. AR genes that are not connected to the chromosome can transfer horizontally and vertically. AR bacteria can diffuse quickly and eliminate naturally from the host if the chicken is not under the pressure of this antibiotic.

关键词： antimicrobial-resistance transfer in vitro enterobacteriaccae diffusion elimination

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Function Identification of the Candidate Disease-Resistance Gene in Cabbage

引用

Agricultural Sciences in China 2008年第3期7卷 314-320页

作者： CAO Bi-hao LEI Jian-jun XIANG Chen-bin CHEN Guo-ju ZENG Guo-ping David J. Oliver ZHAO Shuang LU Ling-ling Horticulture Biotechnology Research Institute the Genetic and Quality hnproved Center of Vegetable South China Agricultural UniversityGuangzhou 510642 P.R.China Department of Botany lowa State University Ames lowa 50011 USA 不详

In order to understand the function of TuR2, a candidate disease-resistance gene was isolated from cabbage, we transformed it into mustard （Brassicajuncea L. Linshicaoyaozi） which was susceptible to TuMV through Agrobacterium tumefacine-mediated method. Transgenic plants were detected by Southern blotting and Northern blotting. Our results confirmed that the TuR2 gene had been integrated into the mustard genome, and it showed different expression levels among primary transplants （T0）. The primary transplants （T0） and the first progenies of transgenic plants （T1） were inoculated with TuMV in a greenhouse. The transgenic plants had high TuMV-resistance, whereas the serious virus disease symptom was observed in CK （no transformation plants）. The TuR2 gene in the first progenies of transgenic plants （T1） showed dominant monogenic inheritance. Compared with CK, the progenies containing TuR2 gene had stronger resistance to TuMV. The TuR2 gene which was isolated from cabbage had the function of TuMV-resistance.

关键词： TuR2 gene function identification TuMV-resistance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unveiling a new regulator: Vacuolar V-ATPase mediates brassinosteroid signaling in Arabidopsis

引用

Molecular Plant 2024年第2期17卷 227-229页

作者： Shikha Malik Justin W.Walley Department of Plant Pathology Entomologyand Microbiologylowa State UniversityAmesIA 50011USA

Plant growth and development are intricately regulated by hormones such as auxins,gibberellins,jamonates,cytokinins,and brassinosteroids(BRs).BRs are a group of plant steroid hormones that play a vital role in plant growth and response to the *** regulate many biological processes including cell elongation,cell division,and male fertility,as well as abiotic and biotic stress responses.

关键词： media fertility brassinosteroid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multi-objective Dynamic Reconfiguration for Urban Distribution Network Considering Multi-level Switching Modes

引用

Journal of Modern Power Systems and Clean Energy 2022年第5期10卷 1241-1255页

作者： Hongjun Gao Wang Ma Yingmeng Xiang Zao Tang Xiandong Xu Hongjin Pan Fan Zhang Junyong Liu College of Electrical Engineering Sichuan UniversityChengdu 610065China Iowa State university Ameslowa50010USA Key Laboratory of Smart Gridof Ministry of Education Tianjin UniversityTianjin 300072China

The increasing integration of photovoltaic generators(PVGs) and the uneven economic development in different regions may cause the unbalanced spatial-temporal distribution of load demands in an urban distribution network(UDN). This may lead to undesired consequences, including PVG curtailment, load shedding, and equipment inefficiency, etc. Global dynamic reconfiguration provides a promising method to solve those challenges. However, the power flow transfer capabilities for different kinds of switches are diverse, and the willingness of distribution system operators(DSOs) to select them is also different. In this paper, we formulate a multi-objective dynamic reconfiguration optimization model suitable for multi-level switching modes to minimize the operation cost, load imbalance, and the PVG curtailment. The multi-level switching includes feeder-level switching, transformer-level switching, and substation-level switching. A novel load balancing index is devised to quantify the global load balancing degree at different levels. Then, a stochastic programming model based on selected scenarios is established to address the uncertainties of PVGs and loads. Afterward, the fuzzy c-means(FCMs) clustering is applied to divide the time periods of reconfiguration. Furthermore, the modified binary particle swarm optimization(BPSO)and Cplex solver are combined to solve the proposed mixed-integer second-order cone programming(MISOCP) model. Numerical results based on the 148-node and 297-node systems are obtained to validate the effectiveness of the proposed method.

关键词： Binary particle swarm optimization(BPSO) dynamic reconfiguration multi-level switching mixed-integer second-order cone programming(MISOCP) urban distribution network(UDN)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Highly efficient and anti-poisoning single-atom cobalt catalyst for selective hydrogenation of nitroarenes

引用

Nano Research 2022年第12期15卷 10006-10013页

作者： Yuemin Lin Renfeng Nie Yuting Li Xun Wu Jiaqi Yu Shaohua Xie Yajing Shen Shanjun Mao Yuzhuo Chen Dan Lu Zongbi Bao Qiwei Yang Qilong Ren Yiwen Yang Fudong Liu Long Qi Wenyu Huang Zhiguo Zhang Key Laboratory of Biomass Chemical Engineering of Ministry of Education Cllege of Chemical and Biological EngineeringZhejiang University38 Zheda RoadHangzhou 310027China U.S.DOE Ames Laboratory lowa State UniversityAmeslowa 50011USA Department of Chemistry Iowa State UniversityAmeslowa 50011USA College of Chemical Engineering Zhengzhou UniversityZhengzhou 450001China Department of Civil Environmentaland Construction EngineeringCatalysis Cluster for Renewable Energy and Chemical Transformations(REACT)Nano Science Technology Center(NSTC)University of Central FloridaOrlandoFL 32816USA Advanced Materials and Catalysis Group Institute of CatalysisDepartment of ChemistryZhejiang UniversityHangzhou 310028China Institute of Zhejiang university-Quzhou Quzhou 324000China

Developing non-precious metal catalysts to selectively reduce functionalized nitroarenes with high efficiency is urgently desirable for the production of value-added ***,we report a novel,efficient,anti-poisoning single-atom cobalt catalyst(Co-NAC)for the highly selective hydrogenation of the nitro to amino group for nitroarenes baring various functional groups,including vinyl,cyano,and *** a combination of structure characterization techniques,we have confirmed that the cobalt species are predominantly present in the form of four-coordinated Co single sites anchored on nitrogen-assembly carbon(NAC)as the ordered mesoporous ***-NAC catalysts enable the full conversion and>99%selectivity with molecular H2 as a green reductant under mild conditions(80℃,2 MPa H2).As for the selective hydrogenation of 3-nitrostyrene,Co-NAC catalyst affords high catalytic productivity(19.7 h-1),which is superior to the cobalt nanoparticles(NPs)catalysts and most of the recently reported Co-based *** is attributed to the highly accessible atomically-dispersed Co active sites,the high surface area with ordered-mesoporous morphology and the prominent high content of nitrogen ***,Co-NAC catalyst displays resistance towards sulfur-containing poisons(20 equivalents)and strong non-oxidizing acid(8 M),showing great potential for continuous application in the chemical industry.

关键词： cobalt single-atom selective hydrogenation nitroarenes 3-nitrostyrene poisoning resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ON DISTRIBUTIVE MODULES AND LOCALLY DISTRIBUTIVE RINGS

引用

Chinese Annals of Mathematics,Series B 1991年第1期12卷 26-32页

作者： K.R.Fuller 薛卫民 Department of Mathematics University of Iowalowa CityIowaU.S.A. Department of Mathematics Fujian Normal UniversityFuzhouFujianChina.

Distributive modules over artinian rings are characterized via module diagrams,andit is shown that a left artinian ring is(two-sided)locally distributive in case its leftindecomposable injective modules and projective modules are *** latter resultis used to show that a locally distributive artinian ring and the endomorphism ring of itsminimal cogenerator have identical diagrams.

关键词： projective identical sided latter rings locally maximal 任尹 algebra indeed

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：