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Characterization of the effects of hyaluronan oligosaccharides on human gut microbiota using a simulated batch fermentation system

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Food science and Human Wellness 2024年

作者： Xinwei Gao Hongkang Zhu Litao Hu Jieyu Sun Wenjie Zuo Ping Liu Yang Wang Guocheng Du Zhen Kang The science Center for Future Foods， Jiangnan university The Key Laboratory of Carbohydrate Chemistry and Biotechnology， Ministry of Education， Jiangnan university The Key Laboratory of Industrial Biotechnology， Ministry of Education， School of Biotechnology， Jiangnan university School of Food science and technology， Jiangnan university

The prebiotic effects of hyaluronan (ha) are widely recognized， contributing to improved gut health and immune modulation. Despite its extensive use as dietary supplement， the specific interactions between ha oligosaccharides (o-has) and the gut microbiome remain largely unexplored. To investigate its role and metabolic fate in gut homeostasis， 200 mg/day of o-has (average molecule weight 1k Da) were added to an automated computer-controlled SIMulator of the Gastrointestinal tract (SIMGI). The results revealed a significant reshaping of the intestinal flora composition by o-has， notably reducing the Firmicutes/Bacteroides ratio. Fermentation of o-has by gut microbiota significantly increased the abundance of Bifidobacteria， Prevotellaceae＿Prevotella， Dialister， Eubacterium， and Sutterella， but decreased that of Catenibacterium， Oscillospira， Klebsiella， and Citrobacter (P hancements in the content of short-chain fatty acids (SCFAs) such as acetic acid， propionic acid and n-butyric acid， highlighting the significant impact of o-has at the genus level. Furthermore， analysis of microbial function predicted the downregulation of pathological events in nine human diseases， particularly infectious ones (parasitic and bacterial). Potential inhibitions were observed in metabolic pathways associated with pentose and glucuronate interconversions as well as cationic antimicrobial peptide resistance. These findings underscore the in vitro prebiotic effects of o-has and their potential relevance in managing diverticular diseases or preventing metabolic disorders through the regulation of gut microbiota.

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A new method for evaluating wedges of steel plates and strips

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Journal of Iron and Steel Research International 2024年第7期31卷 1719-1735页

作者： Xiao-bao Ma Xiao-xin Ma Tao Wang Zhong-kai Ren Yu-cheng Ren College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan 030024ShanxiChina Ministry of Education Engineering Research Center of Advanced Metal Composite Forming technology and Equipment Taiyuan University of TechnologyTaiyuan 030024ShanxiChina National Key Laboratory of Metal Forming technology and Heavy Equipment Taiyuan University of TechnologyTaiyuan 030024ShanxiChina China National Heavy Machinery Research Institute Co. Ltd.Xi'an 710018ShaanxiChina Faculty of Mechanical Engineering Hebei University of ArchitectureZhangjiakou 075000HebeiChina

To overcome the inaccuracy problem of the traditional wedge evaluation of steel plates and strips caused by the ran-domness of the thicknesses of two local points and improve the reliability of the wedge index,the double-centroid method for the wedge evaluation was proposed,and a model based on the centroid theory was ***,an integral model for the discrete thickness values of the cross-section profiles was *** discussion focused on the distinct characteristics of the two-point method,asymmetric method,and double-centroid method in evaluating the asymmetric distribution of *** three methods were employed to evaluate the wedge values of both the theoretical and measured cross-sections of steel plates and strips,and the accuracies of three wedge evaluation models were analyzed and *** results showed that the double-centroid method objectively reflects the degree and variation characteristics of the wedge values of the cross-sections of steel plates and strips,and this method is feasible,reliable,and outstanding.

关键词： Steel plate and strip Wedge Two-point method Double-centroid method Reliability

The Effect of Moisture in Different Altitude Layers on the Eastward Propagation of MJO

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Journal of Meteorological Research 2024年第3期38卷 437-452页

作者： Xiaoyu ZHU Zhong ZHONG Yimin ZHU Yunying LI Yijia HU Yao ha College of Meteorology and Oceanography National University of Defense TechnologyChangsha410000China Key Laboratory for Virtual Geographic Environment School of Geography ScienceNanjing Normal UniversityNanjing210023China Jiangsu Collaborative Innovation Center for Climate Change School of Atmospheric SciencesNanjing UniversityNanjing210000China

In this study,driven by ERA5 reanalysis data,the Weather Research and Forecasting(WRF)version 4.0 was used to investigate the eastward propagation of the Madden-Julian oscillation(MJO)in the tropical atmosphere during December-February(DJF)of 2007/*** experiment with 11 cumulus parameterization schemes respectively shows that the Grell 3D scheme is one of several worse ones in describing MJO *** addition,still by use of the Grell 3D scheme,four nudging assimilation experiments for water vapor in all model vertical layers(Ndg_all),lower layers(Ndg_low),middle layers(Ndg_mid),and upper layers(Ndg_upp)were *** is found that when the water vapor in the model approaches to the observed value,the model performance for MJO activities is improved *** the four nudging simulations,Ndg_all certainly performs *** Ndg_mid is important for the MJO-filtered profiles related to moisture,Ndg_low and Ndg_upp exhibit superiority to Ndg_mid in simulating MJO eastward ***_low has advantages when MJO features are represented by zonal wind at 850 hPa and precipitation because the lower-level MJO-filtered moisture is conducive to the existence of lower-level condensational heating to the east of the MJO convective ***_upp performs better when describing the MJO eastward propagation features by outgoing longwave radiation(OLR)since it can capture the moisture and cloud top temperature of deep convection associated with MJO,as well as front Walker *** results suggest that the lower-level moisture is more important in regulating the MJO eastward propagation,and the observed maximum MJO-filtered moisture in the middle troposphere might be a phenomenon accompanying the MJO deep convection,but not a factor controlling its eastward propagation.

关键词： Madden-Julian oscillation(MJO) nudging technique Weather Research and Forecasting(WRF)model vertical moisture structure

Synthesis of waterborne polyurethane-humic acid cross-linked biomass porous materials for the adsorption of methylene blue

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Chinese Journal of Chemical Engineering 2024年第3期67卷 27-38页

作者： Shanghong Ma Jianbo Qu haitao Zhang Xiubin Cui Peng Ye Qingfei Hu Mingzhen Chao State Key Laboratory of Biobased Material and Green Papermaking Qilu University of TechnologyShandong Academy of SciencesJinan 250353China Faculty of Light Industry Qilu University of TechnologyShandong Academy of SciencesJinan 250353China

A series of adsorbent materials(WPU-hax-y)with a three-dimensional porous structure,green sustainability,and excellent performance were prepared and evaluated for the removal of methylene blue using nontoxic and environmentally friendly waterborne polyurethane as the matrix material and humic acid,a biomass material,as the functional *** newly synthesized adsorbents were characterized by infrared spectroscopy,scanning electron microscopy,specific surface area,and *** effects of contact time(0-8 h),starting concentration(10-100 mg·L^(-1)),pH(3-11),solution temperature(30-60℃),and coexisting ions(Ca2+,Na+,K+,Mg2+)on the performance were ***-first-order,pseudo-second-order,elovich,and intra-particle diffusion models were used to analyze the adsorption kinetics;the Langmuir,Freundlich,Temkin,and Dubin-Radushkovich adsorption isotherms were evaluated;and the adsorption behavior of the adsorbent materials was found to be more appropriate for the pseudo-second-order model for chemical pollutant removal than the Langmuir model,which depends on monolayer ***-ha2-3 stood out with a maximum adsorption capacity of 813.0081 mg·g^(-1) fitted to the pseudo-second-order and 309.2832 mg·g^(-1) fitted to the Langmuir model,showing superior adsorption performance and regenerability.

关键词： Porous media Bioenergy Sustainability Waste water

Excessive manure application stimulates nitrogen cycling but only weakly promotes crop yields in an acidic Ultisol:Results from a 20-year field experiment

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Journal of Integrative Agriculture 2024年第7期23卷 2434-2445页

作者： Song Wan Yongxin Lin hangwei Hu Milin Deng Jianbo Fan Jizheng He Key Laboratory for Humid Subtropical Eco-geographical Processes of Ministry of Education School of Geographical Sciences/School of Carbon Neutrality Future TechnologyFujian Normal UniversityFuzhou 350007China School of Agriculture and Food Faculty of ScienceThe University of MelbourneParkvilleVictoria 3010Australia State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China

Population growth and growing demand for livestock products produce large amounts of manure,which can be harnessed to maintain soil sustainability and crop ***,the impacts of excessive manure application on crop yields,nitrogen(N)-cycling processes and microorganisms remain ***,we explored the effects of 20-year of excessive rates(18 and 27 Mg ha^(–1)yr^(–1))of pig manure application on peanut crop yields,soil nutrient contents,N-cycling processes and the abundance of N-cycling microorganisms in an acidic Ultisol in summer and winter,compared with none and a regular rate(9 Mg ha^(–1)yr^(–1))of pig manure ***-term excessive pig manure application,especially at the high-rate,significantly increased soil nutrient contents,the abundance of N-cycling functional genes,potential nitrification and denitrification activity,while it had a weaker effect on peanut yield and plant *** with manure application,seasonality had a much weaker effect on N-cycling gene *** forest analysis showed that available phosphorus(AP)content was the primary predictor for N-cycling gene abundance,with significant and positive associations with all tested N-cycling *** study clearly illustrated that excessive manure application would increase N-cycling gene abundance and potential N loss with relatively weak promotion of crop yields,providing significant implications for sustainable agriculture in the acidic Ultisols.

关键词： denitrification manure amendment nitrification N-cycling functional genes peanut yields

Towards the performance limit of catenary meta-optics via field-driven optimization

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Opto-Electronic Advances 2024年第5期7卷 33-42页

作者： Siran Chen Yingli ha Fei Zhang Mingbo Pu hanlin Bao Mingfeng Xu Yinghui Guo Yue Shen Xiaoliang Ma Xiong Li Xiangang Luo National Key Laboratory of Optical Field Manipulation science and technology Chinese Academy of SciencesChengdu 610209China State Key Laboratory of Optical Technologies on Nano-Fabrication and Micro-Engineering Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China College of Materials science and Opto-Electronic technology University of Chinese Academy of SciencesBeijing 100049China Research Center on Vector Optical Fields Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China Department of Electrical and Computer Engineering University of California Los Angeles(UCLA)Los AngelesCalifornia 90095USA

Catenary optics enables metasurfaces with higher efficiency and wider bandwidth,and is highly anticipated in the imaging system,super-resolution lithography,and broadband ***,the periodic boundary approximation without considering aperiodic electromagnetic crosstalk poses challenges for catenary optical devices to reach their performance ***,perfect control of both local geometric and propagation phases is realized through field-driven optimization,in which the field distribution is calculated under real boundary *** from other optimization methods requiring a mass of iterations,the proposed design method requires less than ten iterations to get the efficiency close to the optimal *** on the library of shape-optimized catenary structures,centimeter-scale devices can be designed in ten seconds,with the performance improved by ~15%.Furthermore,this method has the ability to extend catenary-like continuous structures to arbitrary polarization,including both linear and elliptical polarizations,which is difficult to achieve with traditional design *** provides a way for the development of catenary optics and serves as a potent tool for constructing high-performance optical devices.

关键词： catenary optics catenary structures field-driven optimization

Construction of coal pitch-based ha-K grafted poly condensates and their excellent anti-temperature and viscosity-reducing properties

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Petroleum science 2024年第4期21卷 2806-2816页

作者： Jing Tan Wei Zhang Xiu-Ling Yan hao Zhou Sher Bahadar Khan Seitkhan Azat Shi-You Yan hao-Jie Ma Xin-Tai Su Xinjiang Key Laboratory of Clean Conversion and High Value Utilization of Biomass Resources College of Chemistry and Chemical Engineering Yili Normal University School of Environment and Energy Guangdong Provincial Key Laboratory of Solid Wastes Pollution Control and Recycling South China University of Technology Drilling Fluid Branch of CNPC Xibu Drilling Engineering Company Limited Department of Chemistry Faculty of Science King Abdulaziz University PO Box 80203 Faculty of Chemistry and Chemical technology Al-Farabi Kazakh National University Urumchi Huatailong Chemical Additives Co. Ltd.

Humic acids(has) are widely used as filtrate and viscosity reducers in drilling fluids. However, their practical utility is limited due to poor stability in salt resistance and high-temperature resistance. Hightemperature coal pitch(CP) is a by-product from coal pyrolysis above 650.C. The substance's molecular structure is characterized by a dense arrangement of aromatic hydrocarbon and alkyl substituents. This unique structure gives it unique chemical properties and excellent drilling performance, surpassing traditional humic acids in drilling operations. Potassium humate is prepared from CP(CP-ha-K) by thermal catalysis. A new type of high-quality humic acid temperature-resistant viscosity-reducer(Graft CP-ha-K polymer) is synthesized with CP-ha-K, hydrolyzed polyacrylonitrile sodium salt(Na-HPAN),urea, formaldehyde, phenol and acrylamide(AAM) as raw materials. The experimental results demonstrate that the most favorable conditions for the catalytic preparation of CP-ha-K are 1 wt% catalyst dosage, 30 wt% KOH dosage, a reaction temperature of 250.C, and a reaction time of 2 h, resulting in a maximum yield of CP-ha-K of 39.58%. The temperature resistance of the Graft CP-ha-K polymer is measured to be 177.39.C, which is 55.39.C higher than that of commercial ha-K. This is due to the abundant presence of amide, hydroxyl, and amine functional groups in the Graft CP-ha-K polymer,which increase the length of the carbon chains, enhance the electrostatic repulsion on the surface of solid particles. After being aged to 120.C for a specified duration, the Graft CP-ha-K polymer demonstrates significantly higher viscosity reduction(42.12%) compared to commercial ha-K(C-ha-K). Furthermore,the Graft CP-ha-K polymer can tolerate a high salt concentration of 8000 mg.L-1, measured after the addition of optimum amount of 3 wt% Graft CP-ha-K polymer. The action mechanism of Graft CP-ha-K polymer on high-temperature drilling fluid is that the Graft CP-ha-K polymer can increase the re

关键词： Viscosity breaker Heat resistance Base mud Graft CP-ha-K polymer CP Salt resistance

New Collective Signatures Based on the Elliptic Curve Discrete Logarithm Problem

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Computers, Materials & Continua 2022年第10期73卷 595-610页

作者： Tuan Nguyen Kim Duy Ho Ngoc Nikolay A.Moldovyan School of Computer science Duy Tan UniversityDa NangVietnam Department of Information technology Ha NoiVietnam ITMO university St.PetersburgRussia

There have been many digital signature schemes were developed based on the discrete logarithm problem on a finite *** this study,we use the elliptic curve discrete logarithm problem to build new collective signature *** cryptosystem on elliptic curve allows to generate digital signatures with the same level of security as other cryptosystems but with smaller *** extend practical applicability and enhance the security level of the group signature protocols,we propose two new types of collective digital signature schemes based on the discrete logarithm problem on the elliptic curve:i)the collective digital signature scheme shared by several signing groups and ii)the collective digital signature scheme shared by several signing groups and several individual *** two new types of collective signatures have combined the advantages of group digital signatures and collective digital *** signatures have a fixed size and do not depend on the number of members participating in the creation of the final collective *** of the advantages of the proposed collective signature protocols is that they can be deployed on top of the available public key infrastructures.

关键词： Elliptic curve signing group individual signer collective signature group signature

Tuning interfacial charge transfer for efficient visible-light-driven photodegradation and simultaneous H_(2)evolution

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Journal of Materials science & technology 2024年第1期168卷 35-49页

作者： Zhiyang Li Yaogang Chen Yinghe Zhang Wei Ai Qian Lei Tingjun Yao Dan Zhong Wenjie Liu Wenbiao Jin Lei Yang State Key Laboratory of Urban Water Resource and Environment Shenzhen Key Laboratory of Organic Pollution Prevention and ControlSchool of Civil and Environmental EngineeringHarbin Institute of Technology ShenzhenShenzhen 518055China Key Laboratory of Northwest Water Resources Environment and EcologyMinistry of EducationSchool of Environmental and Municipal EngineeringXi’an University of Architecture and TechnologyXi’an 710055China CNAS Accredited Test Center Guangdong Engineering Technology Research Center of Air PurificationHealthlead Co.Ltd.Shenzhen 518055China School of science Harbin Institute of Technology ShenzhenShenzhen 518055China

The edge-graphitized carbon nitride(C_(3)N_(4)-C g)was prepared by secondary pyrolysis to construct ZnO/C_(3)N_(4)-C g(ZCN)type-Ⅱheterojunction photocatalyst via a facile sonication dispersion method,which achieved∼7.04-fold and∼18.3-fold enhanced visible-light-driven photocatalytic performance for refrac-tory micropollutant removal and simultaneous hydrogen(H_(2))evolution respectively compared to con-ventional ZnO/g-C_(3)N_(4)Step-scheme *** apparent quantum efficiency of the ZCN_(0.4)het-erojunction reaches 0.92%(λ=420 nm).Such excellent performance stems from that the edge-graphene moieties stitched onto the interface of heterojunction extend light absorption to the full visible spec-trum,meanwhile,the built-in electric field generated during Fermi level alignment accompanying fa-vorable band-bending structure provides an effective pathway for the rapid migration of photoinduced electrons via the edge graphene channel to improve interfacial charge separation ***,the midgap states introduced in ZCN heterojunction could temporarily retain photoexcited electrons to effectively inhibit the in situ carrier recombination for improved photocatalytic H_(2)***,ZCN/peroxymonosulfate system exhibited excellent anti-interference performance against complex water bodies under visible illumination due to the synergistic effect between the co-existing anions and organic ***,the eco-friendly nature of the ZCN/peroxymonosulfate system showed no biotoxicity of reaction filtrate on cell proliferation after treatment,which avoided secondary ***-ering the outstanding performance in photocatalysis,the ZCN system exhibits broad potential for practical applications in water pollution control and green energy production.

关键词： ZnO C_(3)N_(4)-C g Heterojunction Photodegradation Hydrogen evolution