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Endoscopic techniques for the diagnosis of pancreatic cystic lesions

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World Journal of Gastroenterology 2025年第1期31卷 1-7页

作者： Sahib Singh Saurabh Chandan Rakesh Vinayek Jahnvi Dhar Jayanta Samanta Gabriele Capurso Ivo Boskoski Cristiano Spada Jorge D Machicado Stefano Francesco Crinò Antonio Facciorusso Department of Internal Medicine Sinai HospitalBaltimoreMD 21215United States Division of Gastroenterology and Hepatology Creighton University School of MedicineOmahaNE 68131United States Department of Gastroenterology Sinai Hospital of BaltimoreBaltimoreMD 21215United States Department of Gastroenterology Postgraduate Institute of Medical Education and ResearchChandigarh 160012India Division of Pancreato-Biliary Endoscopy and Endosonography Pancreas Translational and Clinical Research CenterIRCCS San Raffaele Scientific InstituteVita-Salute San Raffaele UniversityMilano 20132Italy Digestive Endoscopy Unit Fondazione Policlinico Universitario Agostino Gemelli IRCSSUniversitàCattolica del Sacro Cuore di RomaCenter for Endoscopic Research Therapeutics and TrainingRoma 00168Italy Department of Gastroenterology and Endoscopy Catholic UniversityRoma 00168Italy Department of Gastroenterology University of Michigan HealthAnn ArborMI 48107United States Department of Endoscopy University of VeronaVerona 37121VenetoItaly Gastroenterology Unit Department of Medical and Surgical SciencesUniversity of FoggiaFoggia 71122Italy

Pancreatic cysts are mostly incidental findings on computed tomography or magnetic resonance imaging scans,with few patients presenting with abdominal pain or other *** accurate diagnosis of cysts is important as management depends on the type(neoplastic or non-neoplastic).Cross-sectional imaging is fast being replaced with endoscopic ultrasound(EUS)and various techniques based on that such as EUS-guided fine needle aspiration,EUS-guided needle confocal laser endomicroscopy,EUS-through-the-needle biopsy,and contrast-enhanced *** studies have reported varying diagnostic and adverse event rates with these *** addition,American,European,and Kyoto guidelines for the diagnosis and management of pancreatic cysts have provided different *** this editorial,we elaborate on the clinical guidelines,recent studies,and comparison of different endoscopic methods for the diagnosis of pancreatic cysts.

关键词： Endoscopic ultrasound Fine needle aspiration Needle confocal laser endomicroscopy Through-the-needle biopsy Contrast-enhanced endoscopic ultrasound

Insular mammalian fauna dynamics and paleogeography:A lesson from the Western Mediterranean islands

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Integrative Zoology 2018年第1期13卷 2-20页

作者： Maria Rita PALOMBO Department of Earth Science Sapienza University of RomeRomaItaly CNR-IGAG Monterotondo(Roma)Italy

Since the time of Darwin(1859)and Wallace(1869),islands have been regarded by scientists as a prime target for scrutinizing the forces that may influence evolution and diversification and important elements in biogeographic *** research aims to scrutinize whether and to what extent the composition and structure of past mammal insular faunas and their changes through time may provide sound clues for inferring the paleogeographical evolution of a *** a case study,I critically analyzed the dynamics shown by the Plio-Pleistocene mammalian fauna of 3 Western Mediterranean insular districts,the Balearic Islands,Sardinia and Sicily,each characterized by its own peculiar paleobiogeographical evolutionary *** revision of faunas and the critical analysis of the dispersal ability of the ancestors of island settlers have allowed hypothesizing on the time and mode of island *** results obtained confirm that the early isolation of the Balearic Islands from the mainland led to the establishment of an endemic fauna since the pre-Messinian Miocene(?Astaracian European Land Mammal Age,MN7/8),and that Sardinia has definitely been isolated since the Pliocene,although dispersal events led to some faunal turnovers during the *** addition,the results suggest for Sicily a complex,still imperfectly disentangled history of alternate phases of complete separation and sporadic,more or less difficult connections with southern Italy.

关键词： dispersal islands mammal Plio–Pleistocene Western Mediterranean

Helicobacter pylori infection and drugs malabsorption

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World Journal of Gastroenterology 2014年第30期20卷 10331-10337页

作者： Edith Lahner Camilla Virili Maria Giulia Santaguida Bruno Annibale Marco Centanni Gastrointestinal Unit Department of Digestive and Liver Disease"Sapienza" University of Roma00189 RomaItaly Endocrinology Unit Department of Medico-Surgical Sciences and Biotechnologies"Sapienza" University of Roma04100 LatinaItaly

Drug absorption represents an important factor affecting the efficacy of oral drug *** secretion and motility seem to be critical for drug absorption.A causal relationship between impaired absorption of orally administered drugs and Helicobacter pylori(***)infection has been *** have been reported between poor bioavailability of l-thyroxine and l-dopa and *** *** to the Maastricht Florence Consensus Report on the management of *** infection,*** treatment improves the bioavailability of both these drugs,whereas the direct clinical benefits to patients still await to be *** strong seems the association between *** infection and other drugs malabsorption,such as delavirdine and *** exact mechanisms forming the basis of the relationship between *** infection and impaired drugs absorption and/or bioavailability are not fully *** infection may trigger a chronic inflammation of the gastric mucosa,and impaired gastric acid secretion often *** reduction of acid secretion closely relates with the wideness and the severity of the damage and may affect drug *** minireview focuses on the evidence of *** infection associated with impaired drug absorption.

关键词： Drug malabsorption Helicobacter pylori gastritis Gastric hypoacidity Thyroxine treatment Thyroxine malabsorption Human immunodeficiency virus Delavirdine L-dopa Parkinson's disease Ketaconazole

Testing of the Ultra-Micro Gas Turbine Devices (1 - 10 kW) for Portable Power Generation at university of roma 1: First Tests Results

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Engineering（科研） 2013年第5期5卷 481-489页

作者： Alfonso Calabria Roberto Capata Mario Di Veroli Gianluca Pepe Department of Mechanical and Aerospace Engineering Sapienza—University of Roma Roma Italy

The ever increasing development of portable electronics has led to a higher demand for compact and reliable power sources. Significant resources are being presently dedicated to the study of micro machined gas turbines, because of their remarkable power density. The paper reports the procedures and the results of a series of tests conducted at the Department of Mechanical & Aerospace Engineering of university of roma 1, to obtain the map of an ultra-micro gas turbine device, and the head losses and the combustion efficiency of the corresponding ultra-micro combustion chamber, fed by a mixture of butane and propane. This work is a part of a research aimed at the conception, design and prototyping of an ultra-micro thermo-electrical device for portable power generation. The novelty of the research consists in the fact that the thermal engine is a (ultra-micro) gas turbine set. In a subsequent stage, several different configurations have been assessed to select the most proper geometry and structural characteristics of the most relevant components (radial compressor, radial turbine, combustion chamber, electric motor and generator, bearings, regenerative heat exchanger).

关键词： Ultra-Micro Components Gas Turbine Radial Compressor Combustion Chamber

A simplified Parisi ansatz

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Communications in Theoretical Physics 2021年第5期73卷 92-101页

作者： Simone Franchini sapienza Universita di roma 1 Piazza Aldo Moro00185 RomaItaly

Based on simple combinatorial arguments,we formulate a generalized cavity method where the Random Overlap Structure(ROSt)probability space of Aizenmann,Sims and Starr is obtained in a constructive way,and we use it to... 详细信息

关键词： Sherrington–Kirkpatrick model cavity methods Parisi formula

The effect of different intensity measures and earthquake directions on the seismic assessment of skewed highway bridges

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Earthquake Engineering and Engineering Vibration 2017年第1期16卷 165-179页

作者： M.Bayat F.Daneshjoo N.Nistico Department of Civil and Environmental Engineering Tarbiat Modares UniversityTehranIran Department of Structural and Geotechnical Engineering Universitd degli Studi di Roma'La Sapienza'RomaItaly

In this study the probable seismic behavior of skewed bridges with continuous decks under earthquake excitations from different directions is investigated. A 45° skewed bridge is studied. A suite of 20 records is used to perform an Incremental Dynamic Analysis （IDA） for fragility curves. Four different earthquake directions have been considered： -45°, 0°, 22.5, 45°. A sensitivity analysis on different spectral intensity measures is presented; efficiency and practicality of different intensity measures have been studied. The fragility curves obtained indicate that the critical direction for skewed bridges is the skew direction as well as the longitudinal direction. The study shows the importance of finding the most critical earthquake in understanding and predicting the behavior of skewed bridges.

关键词： skewed highway bridge earthquake direction spectral intensity measure analytical fragility curve

Non-locality and collective emission in disordered lasing resonators

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Light(Science & Applications) 2013年第1期2卷 79-84页

作者： Marco Leonetti Claudio Conti Cefe Lopez ISC-CNR UOS Sapienza00185 RomaItaly Institute for Material Science Madrid(ICMM-CSIC) 28049 MadridSpain Department of Physics University SapienzaI-00185 RomaItaly

Random lasing is observed in optically active resonators in the presence of *** the optical cavities involved are open,the modes are coupled,and energy may pour from one state to another provided that they are spatially *** the electromagnetic modes are spatially localized,our system may be actively switched to a collective state,presenting a novel form of non-locality revealed by a high degree of spectral correlation between the light emissions collected at distant *** a nutshell,light may be stored in a disordered nonlinear structure in different fashions that strongly differ in their spatial *** effect is experimentally demonstrated and theoretically explained in titania clusters embedded in a dye,and it provides clear evidence of a transition to a multimodal collective emission involving the entire spatial extent of the disordered *** results can be used to develop a novel type of miniaturized,actively controlled all-optical chip.

关键词： collective emission disorder nanophotonics random lasing

Compressing deep-quaternion neural networks with targeted regularisation

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CAAI Transactions on Intelligence Technology 2020年第3期5卷 172-176页

作者： Riccardo Vecchi Simone Scardapane Danilo Comminiello Aurelio Uncini Department of Information Engineering Electronics and Telecommunications(DIET)‘Sapienza’University of RomeRoma Lazio 00185Italy

In recent years,hyper-complex deep networks(such as complex-valued and quaternion-valued neural networks–QVNNs)have received a renewed interest in the *** find applications in multiple fields,ranging from image reconstruction to 3D audio *** to their real-valued counterparts,quaternion neural networks require custom regularisation strategies to avoid *** addition,for many real-world applications and embedded implementations,there is the need of designing sufficiently compact networks,with few weights and ***,the problem of regularising and/or sparsifying QVNNs has not been properly addressed in the literature as of *** this study,the authors show how to address both problems by designing targeted regularisation strategies,which can minimise the number of connections and neurons of the network during *** this end,they investigate two extensions of ℓ1 and structured regularisations to the quaternion *** the authors’experimental evaluation,they show that these tailored strategies significantly outperform classical(realvalued)regularisation approaches,resulting in small networks especially suitable for low-power and real-time applications.

关键词： networks neural valued

The "meso" of the rectum and the "meso" of the pancreas: similar terms but distinct concepts in surgical oncology

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Hepatobiliary & Pancreatic Diseases International 2015年第5期14卷 548-551页

作者： Nadia Peparini Roberto Caronna Piero Chirletti Azienda Sanitaria Locale roma H-Distretto 3 Department of Surgical Sciences Sapienza University of Rome

A correspondence between the ＂meso＂ of the rectum and of the pancreas has recently been reported. Here we highlight the differences between mesorectum and mesopancreas. Based on anatomical findings from a series of 89 consecutive pancreaticoduodenectomies and 71 consecutive total mesorectal excisions, we observed that in contrast to the mesorectum, the mesopancreas did not have well-defined anatomic boundaries and was continuous and connected through its components with the para-aortic area. In rectal cancer,tumor deposits and nodal involvement could be confined to the mesorectum（i.e., within the mesorectal fascia）, whereas in pancreatic carcinoma, tumor deposits and nodal metastases occurred in the boundless mesopancreatic area. Total mesorectal excision was made en bloc with the rectum by dissecting along the mesorectal fascia; this was not the case for mesopancreatic excision since anatomical demarcation of the mesopancreas did not exist. Moreover, the growth pattern of pancreatic cancer showed greater dispersion, which was more prominent at the invasive front of the tumor and could potentially affect the status of the resection margin. These findings indicate that the mesorectum and mesopancreas are completely distinct from the pathological, surgical, and oncological standpoints.

关键词： pancreatic head carcinoma surgical procedure therapy pancreatic cancer