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Effects of ciprofloxacin on testicular tissue and sperm quality in rabbits

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Asian pacific Journal of Reproduction 2020年第2期9卷 83-88页

作者： Reza Kheirandish Ladan Emadi Baharak Akhtardanesh Shahrzad Azizi Masoud Imani Fatemeh Mahmoodabadi Fereshteh Irani Homa Shokrizadeh Department of Pathobiology Faculty of Veterinary MedicineShahid Bahonar University of KermanKermanIran Department of Basic Sciences Faculty of Veterinary MedicineShahid Bahonar University of KermanKermanIran Department of Clinical Sciences Faculty of Veterinary MedicineShahid Bahonar University of KermanKermanIran Faculty of Veterinary Medicine Shahid Bahonar University of KermanKermanIran

Objective:To investigate the hormonal,histopathological toxicity and sperm quality of ciprofloxacin in male genital system in the rabbit ***:Twenty adult New Zealand male rabbits were randomly divided into the treatment and control groups,and respectively received 30 mg/kg/day ciprofloxacin and normal saline intraperitoneally for 14 *** samples and testicular tissues were taken for testosterone by enzyme linked immunosorbent assay method,and measurement of histopathologic and histomorphometric investigations was made on the 14th day of the experiment and 56 days after the last dose of ***,epididymis sperm sample was collected for quality ***:On day 14 of the experiment,histopathologic examination revealed severe degenerative changes in the epithelium of seminiferous tubules and loss of all germ cells in most tubes in the treatment *** the histomorphometric study,significant reductions in the seminiferous tubules diameter,epithelium height,and Johnsen’score were *** day 56 after the last dose of ciprofloxacin,the seminiferous tubules revealed regeneration in the treatment group and no significant difference was observed in the spermatogenesis parameters except epithelial height parameter between the control group and the treatment *** sperm quality parameters were significantly decreased on day 56 after the last dose of *** levels did not significantly change during the follow-ups ***:There is potential reversible testicular toxicity for ciprofloxacin in the rabbit model in according to relative regeneration of spermatogenic epithelium after 56 days of last dose of *** quality will be improved with a delay after complete regeneration of seminiferous tubules.

关键词： Ciprofloxacin Testis Rabbits Histopathology Testosterone Histomorphometry

Performance improvement of a crumb rubber modified bitumen using recycled glass powder

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Journal of Zhejiang university-Science A(Applied Physics & Engineering) 2013年第11期14卷 805-814页

作者： Mojtaba GHASEMI Seyed Morteza MARANDI Department of Civil Engineering Shahid Bahonar UniversityKerman 761691 4111 Iran

In this study, the efficiency of bitumen and asphalt mixtures modified with crumb rubber(CR) and recycled glass powder(RGP) is evaluated. From an environmental point of view, the application of RGP in asphalt mixtures is considered beneficial since it prevents accumulation of waste glass in the natural environment. Rheological and mechanical properties of modified bitumen samples were investigated by laboratory methods such as bitumen conventional tests and dynamic shear rheometer(DSR), and also by asphalt mixture performance tests including Marshall stability, indirect tensile strength(ITS),compressive strength, and indirect tensile stiffness modulus. The results showed that the application of RGP in place of CR has no negative impact on the efficiency of bitumen and asphalt mixtures and even improves their engineering properties except for the toughness index(TI). Moreover, a modification with 5% CR and 5% RGP in asphalt mixtures results in the best overall performance.

关键词： Crumb rubber(CR) Recycled glass powder(PGP) Rheological properties Performance testing Stone matrix asphalt(SMA)

Herd-prevalence of Coxiella burnetii(Q fever) antibodies in dairy cattle farms based on bulk tank milk analysis

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Asian Pacific Journal of Tropical Medicine 2011年第1期4卷 58-60页

作者： Mohammad Khalili Ehsanollah Sakhaee Mohammad Reza Aflatoonian Naser Shahabi-Nejad Research Center of Tropical and Infectious Diseases Kerman University of Medical SciencesKermanIran Department of Pathobiology School of Veterinary MedicineShahid Bahonar University of KermanIran Department of Clinical Sciences School of Veterinary MedicineShahid Bahonar University of KermanIran

Objective:To determine the prevalence of Coxiella burnetii(***) antibody positive randomly selected dairy herds in southeast Iran(kerman).Methods:Bulk tank milk samples were collected randomly from 44 sufficiently large commercial dairy herds,included near 12 000 dairy cattle,in kerman(The largest province of Iran),southeast *** samples were tested for antibodies against *** using the commercial CHEKIT(?) Q fever antibody ELISA Test Kit(Idexx,Liebefeld-Bern,Switzerland).Results:The prevalence of positive,negative and intermediate herds were 45.4%,43.2%and 11.4%,***:The result supports the hypothesis of high prevalence and endemic pattern of Q fever in *** investigation highlights the importance of further studies on Q fever in Iran.

关键词： Q fever Coxiella burnetii Bulk tank milk Dairy cattle ELISA Iran

The impact of COVID-19 on liver injury in various age

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World Journal of Virology 2023年第2期12卷 91-99页

作者： Amin Sadeghi Dousari Seyed Soheil Hosseininasab Fatemeh Sadeghi Dousari Masoumeh Fuladvandi Naghmeh Satarzadeh Department of Microbiology Jiroft University of Medical SciencesJiroft ***Iran Faculty of Pharmacy Kerman University of Medical SciencesKerman ***Iran Department of Midwifery Jiroft University of Medical SciencesJiroft ***Iran Department of Nursing Aligoudarz School of NursingLorestan University of Medical SciencesKhorramabad ***Iran Department of Pharmaceutical Biotechnology Kerman University of Medical SciencesKerman ***Iran

The coronavirus disease 2019(COVID-19)disease was first detected in December 2019 in Wuhan,*** disease is currently one of the most important global health *** novel coronavirus COVID-19 is a respiratory illness,that has caused a deadly pandemic that is spreading rapidly around the *** is not only a respiratory system virus that causes severe lung disease,but also a systemic disease agent that can affect all *** with COVID-19 disease usually have respiratory signs,however,the liver disorder is not an uncommon *** addition,many studies around the world have revealed that the liver is injured to various degrees in patients with severe acute respiratory syndrome coronavirus 2 *** review mainly focuses on the impact of COVID-19 on Liver Injury at various ages.

关键词： Liver injury Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus 2 Minireview

Mathematical and statistical modeling of morphometric and planar parameters of barchans in Pashoeyeh Erg in the west of Lut Desert,Iran

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Journal of Arid Land 2021年第8期13卷 801-813页

作者： Hossein GHAZANFARPOUR Mohsen POURKHOSRAVANI Sayed H MOUSAVI Ali MEHRABI Department of Geography and Urban Planning Shahid Bahonar University of KermanKerman ***Iran Department of Geography and Ecotourism Faculty of Natural Resources and GeosciencesUniversity of KashanKashan ***Iran

Barchan dunes are among the most common accumulative phenomena made by wind erosion,which are usually formed in regions where the prevailing wind direction is almost constant throughout the year and there is not enough sand to completely cover the land *** are among the most common windy landscapes in Pashoueyeh Erg in the west of Lut Desert,*** study aims to elaborate on morphological properties of barchans in this region using mathematical and statistical *** results of these methods are very important in investigating barchan shapes and identifying their *** shapes were mathematically modeled by simulating them in the coordinate system through nonlinear parabolic equations,so that two separate equations were calculated for barchan windward and slip-face *** type and intensity of relationships between barchan morphology and mathematical parameters were determined by the statistical *** results indicated that the existing relationships followed the power correlation with the maximum coefficient of determination and minimum error of *** the above two methods is a powerful basis for stimulating barchans in virtual and laboratory *** most important result of this study is to convert the mathematical and statistical models of barchan morphology to each *** length is one of the most important parameters of barchan parabolas,suggesting different states of barchans in comparison with each *** the barchan's focal length decreases,its opening becomes narrower,and the divergence of the barchan's horns *** with longer focal length have greater width,dimensions,and *** general,identifying and estimating the morphometric and planar parameters of barchans is effective in how they move,how much they move,and how they behave in the *** cases play an important role in the management of desert areas.

关键词： barchan dunes desert parabolic equations statistical model wind erosion Pashoueyeh Erg Lut Desert

Classification and assessment of rock mass parameters in Choghart iron mine using P-wave velocity

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Journal of Rock Mechanics and Geotechnical Engineering 2017年第2期9卷 318-328页

作者： Mohammadreza Hemmati Nourani Mohsen Taheri Moghadder Mohsen Safari Department of Mining and Metallurgy Yazd UniversityYazdIran Department of Mining Engineering Shahid Bahonar University of KermanKermanIran Department of Mining Engineering Birjand University of TechnologyBirjandIran

Engineering rock mass classification,based on empirical relations between rock mass parameters and engineering applications,is commonly used in rock engineering and forms the basis for designing rock *** basic data required may be obtained from visual observation and laboratory or field ***,owing to the discontinuous and variable nature of rock masses,it is difficult for rock engineers to directly obtain the specific design parameters *** an alternative,the use of geophysical methods in geomechanics such as seismography may largely address this *** this study,25 seismic profiles with the total length of 543 m have been scanned to determine the geomechanical properties of the rock mass in blocks Ⅰ,Ⅲ and Ⅳ-2 of the Choghart iron ***,rock joint measurements and sampling for laboratory tests were *** results show that the rock mass rating（RMR） and Q values have a close relation with P-wave velocity parameters,including P-wave velocity in field(V;).P-wave velocity in the laboratory(V;) and the ratio of V;V;(i.e.K;= V;/V;.However,Q value,totally,has greater correlation coefficient and less error than the RMR,In addition,rock mass parameters including rock quality designation（RQD）,uniaxial compressive strength（UCS）,joint roughness coefficient（JRC） and Schmidt number（RN） show close relationship with P-wave *** equation based on these parameters was obtained to estimate the P-wave velocity in the rock mass with a correlation coefficient of 91%.The velocities in two orthogonal directions and the results of joint study show that the wave velocity anisotropy in rock mass may be used as an efficient tool to assess the strong and weak directions in rock mass.

关键词： Rock mass classification P-wave velocity Q system Rock mass rating(RMR) Geophysical methods

Experimental study on the effect of bottomless structure in front of a bottom outlet on a sediment ?ushing cone

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International Journal of Sediment Research 2021年第3期36卷 335-347页

作者： Hadi Haghjouei Majid Rahimpour Kourosh Qaderi Sameh A.Kantoush Department of Water Engineering Shahid Bahonar University of Kerman

One of the main problems in reservoirs is sedimentation which reduces the operating life of dams if a proper plan and analysis method are not in *** techniques to manage sediment in reservoirs include several sustainable management techniques that route sediment through or around the *** of the main economical methods in arid and semi-arid regions is pressurized flushing using moderate drawdown of the water level of the reservoir to evacuate sediment deposited behind *** the current study,the effect of a new structure called a dendritic bottomless extended （DBE） outlet structure at three angles of 30°,45°,and 60° on pressurized flushing efficiency was ***,45 experiments were designed for three discharge rates （Q;） ,three sediment levels （H;）,four types of structure,and a no-structure condition （reference test）.The results indicated that the DBE structure with a 30° angle between the branches,a sedimentary dimensionless index of ■,and a flow dimensionless index of ■（where g is the acceleration of gravity and Do is the diameter of the bottom outlet） lead to 10-fold increase in the sediment flushing cone dimensions and sediment removal efficiency compared to the results of the reference ***,according to a statistical analysis of the results,a dimensionless equation for calculating the sediment flushing cone dimensions was developed for the tested sediment characteristics.

关键词： Reservoir Sediment removal efficiency Sediment flushing cone Bottom outlet Dendritic bottomless extended structure

Critical care nurses＇ attitude towards life-sustaining treatments in South East Iran

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World Journal of Emergency Medicine 2016年第1期7卷 59-64页

作者： Farideh Razban Sedigheh Iranmanesh Hasan Eslami Aliabadi Mansooreh Azzizadeh Forouzi Neuroscience Research Center Institute of Neuropharmacology University of Medical Sciences Kerman Iran School of Nursing and Midwifery Kerman University of Medical Sciences Kerman Iran Birjand university of Medical Sciences Birjand Iran

BACKGROUND:Life-sustaining treatments(LSTs)may prolong life but greatly decrease the quality of *** factor influencing decision-making about withholding and withdrawing these treatments is the attitude of *** study aimed to evaluate the attitude of critical care nurses towards life-sustaining treatments in South East ***:In this cross-sectional study,"Ethnicity and Attitudes towards Advance Care Directives Questionnaire"was used to investigate the attitude of 104 critical care nurses towards lifesustaining treatments in three hospitals affiliated to kerman university of Medical ***:The findings of this study indicated that although a majority of critical care nurses(77%)did not have personal desire for use of LSTs including CPR and mechanical ventilation,they had moderately negative to neutral attitude towards general use of LSTs(2.95 of 5).CONCLUSIONS:These findings suggest that nurses'attitude towards LSTs can be changed by inclusion of specific courses about death,palliative care and life-sustaining treatments in undergraduate and postgraduate nursing *** Muslim nurses about religious aspects of LSTs may also improve their attitudes.

关键词： Life-sustaining treatments Critical care nurse Attitude South East Iran

Simultaneous investigation of blast induced ground vibration and airblast effects on safety level of structures and human in surface blasting

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International Journal of Mining Science and Technology 2014年第5期24卷 663-669页

作者： Faramarzi Farhad Ebrahimi Farsangi Mohammad Ali Mansouri Hamid Department of Mining Engineering Shahid Bahonar University of Kerman

The significance of studying, monitoring and predicting blast induced vibration and noise level in mining and civil activities is justified in the capability of imposing damages, sense of uncertainty due to negative psychological impacts on involved personnel and also judicial complaints of local inhabitants in the nearby area. This paper presents achieved results during an investigation carried out at Sungun Copper Mine, Iran. Besides, the research also studied the significance of blast induced ground vibration and airblast on safety aspects of nearby structures, potential risks, frequency analysis, and human *** to the United States Bureau of Mines(USBM) standard, the attenuation equations were developed using field records. A general frequency analysis and risk evaluation revealed that: 94% of generated frequencies are less than 14 Hz which is within the natural frequency of structures that increases risk of damage. At the end, studies of human response showed destructive effects of the phenomena by ranging between 2.54 and 25.40 mm/s for ground vibrations and by the average value of 110 dB for noise levels which could increase sense of uncertainty among involved employees.

关键词：安全水平地面振动结构喷砂表面喷气爆炸人类