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Time and Dose-related Effects of the Pyrethroid Fluvalinate on Haemolymph Carbohydrates and Gut Lipids of Honeybees,Following in vivo Injection of very Low Doses

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Biomedical and Environmental Sciences 1993年第2期6卷 145-153页

作者： K.M'DIAYE M.BOUNIAS university University of AvignonBiomathematics & Toxicology23 rue du 58eR.I.F 84000 AvignonFranceof AvignonBiomathematics & Toxicology23 rue du 58eR.I.F 84000 AvignonFrance

The injection to emerging adult workerbees with fluvalinate doses ranging from 1 femtomol to 1 nanomol per individual resulted in a reduction of haemolymph carbohydrate concentrations, particularly at the lowest dose 1 hour after injections. At the same time, a large increase was observed for triacylglycerols and to a much lesser extent for steroids and phospholipids with 0.1 picomol per bee. By contrast, fatty acids, steroids and triacylglycerols exhibited a depress at the higher dose. Most responses were thus biphasic, showing that much attention should be paid to the effects of very low doses of pesticide.

关键词： Time and Dose-related Effects of the Pyrethroid Fluvalinate on Haemolymph Carbohydrates and Gut Lipids of Honeybees,Following in vivo Injection of very Low Doses very

Performance of beacon safety message dissemination in Vehicular Ad hoc NETworks (VANETs)

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Journal of Zhejiang university-Science A(Applied Physics & Engineering) 2007年第12期8卷 1990-2004页

作者： YOUSEFI Saleh FATHY Mahmood BENSLIMANE Abderrahim Computer Engineering Faculty Iran University of Science and TechnologyNarmak Tehran 16846-13114 Tehran Iran Laboratoire d'Informatique d'avignon LIA 339 chemin des Meinajaries BP 1228-84911 Avignon cedex 9 France

Currently, there is a growing belief that putting an IEEE 802.11-like radio into road vehicles can help the drivers to travel more safely. Message dissemination protocols are primordial for safety vehicular applications. There are two types of safety messages which may be exchanged between vehicles: alarm and beacon. In this paper we investigate the feasibility of deploying safety applications based on beacon message dissemination through extensive simulation study and pay special attention to the safety requirements. Vehicles are supposed to issue these messages periodically to announce to other vehicles their current situation and use received messages for preventing possible unsafe situations. We evaluate the performance of a single-hop dissemination protocol while taking into account the quality of service (QoS) metrics like delivery rate and delay. We realize that reliability is the main concern in beacon message dissemination. Thus, a new metric named effective range is defined which gives us more accurate facility for evaluating QoS in safety applications specifically. Then, in order to improve the performance, the effects of three parameters including vehicle's transmission range, message transmission's interval time and message payload size are studied. Due to special characteristics of the safety applications, we model the relationship between communication-level QoS and application-level QoS and evaluate them for different classes of safety applications. As a conclusion, the current technology of IEEE 802.11 MAC layer has still some challenges for automatic safety applications but it can provide acceptable QoS to driver assistance safety applications.

关键词： Safety applications Inter-vehicle communications Vehicular Ad hoc NETworks (VANETs) Application level QoS Effective range

Specific alterations of regional myocardial work in strength-trained athletes using anabolic androgenic steroids compared to athletes with genetic hypertrophic cardiomyopathy

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Journal of Sport and Health Science 2023年第4期12卷 477-485页

作者： Antoine Grandperrin Frédéric Schnell Erwan Donal Elena Galli Christophe Hedon Olivier Cazorla Stéphane Nottin avignon university LaPEC UPR 4278Avignon F-84000France Rennes university CHU RennesInsermLTSI-UMR 1099Rennes F-35000France Montpellier university PhyMedExpINSERMCNRSPhysiology and Experimental Heart and Muscle MedicineMontpellier 34295France

Background:Strength-trained athletes using anabolic androgenic steroids(AAS)have left ventricular(LV)hypertrophy and myocardial fibrosis that can lead to sudden cardiac death.A similar feature was described in athletes with hypertrophic cardiomyopathy(HCM),which complicates the diagnosis for *** this context,we aimed to compare the LV function of the 2 populations by measuring global and regional strain and myocardial work using speckle-tracking ***:Twenty-four strength-trained asymptomatic athletes using AAS(AAS-Athletes),22 athletes diagnosed with HCM(HCM-Athletes),and 20 healthy control athletes(Ctrl-Athletes)underwent a resting echocardiography to assess LV *** evaluated LV global and regional strains and myocardial work,with an evaluation of the constructive work(CW),wasted work,and work efficiency(WE).Results:Compared to Ctrl-Athletes,both AAS-Athletes and HCM-Athletes had a thicker interventricular septum,with maj ored values in *** strain was reduced in AAS-Athletes and even more in ***,global WE was significantly diminished in both AAS and HCM-Athletes(93%±2%in Ctrl-Athletes,90%±4%in AAS-Athletes,and 90%±5%in HCM-Athletes(mean±SD);p<0.05).Constructive work and WE regional analysis showed specific alterations,with the basal septal segments preferentially affected in AAS-Athletes,and both septal and apical segments affected in ***:The regional evaluation of myocardial work reported specific alterations of the major LV hypertrophy induced by the regular use of AAS compared to the LV hypertrophy due to *** finding could help clinicians to differentiate between these 2 forms of pathological hypertrophy.

关键词： Anabolic androgenic steroids Hypertrophic cardiomyopathy Left ventricular function Myocardial work Speckle-tracking echocardiography

A time fractional model to represent rainfall process

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Water Science and Engineering 2014年第1期7卷 32-40页

作者： Jacques GOLDER Maminirina JOELSON Marie-Christine NEEL Liliana DI PIETRO Department of Physics University of Avignon Mediterranean Environment and Agro-Hydro System Modelisation Laboratory French National Institute for Agricultural Research

This paper deals with a stochastic representation of the rainfall process. The analysis of a rainfall time series shows that cumulative representation of a rainfall time series can be modeled as a non-Gaussian random walk with a log-normal jump distribution and a time-waiting distribution following a tempered a-stable probability law. Based on the random walk model, a fractional Fokker-Planck equation （FFPE） with tempered a-stable waiting times was obtained. Through the comparison of observed data and simulated results from the random walk model and FFPE model with tempered a-stable waiting times, it can be concluded that the behavior of the rainfall process is globally reproduced, and the FFPE model with tempered a-stable waiting times is more efficient in reproducing the observed behavior.

关键词： rainfall process heavy-tailed probability distribution tempered a-stable probability law log-normal law Hurst exponent continuous time random walk model fractional Fokker-Planck equation

Estimates of Maize Plant Density from UAV RGB Images Using Faster-RCNN Detection Model:Impact of the Spatial Resolution

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Plant Phenomics 2021年第1期3卷 181-196页

作者： K.Velumani R.Lopez-Lozano S.Madec W.Guo J.Gillet A.Comar F.Baret Hiphen SAS 120 Rue Jean DaussetAgroparcBâtiment Technicité84140 AvignonFrance INRAE UMR EMMAHUMT CAPTE228 Route de l'AérodromeDomaine Saint Paul-Site Agroparc CS 4050984914 Avignon Cedex 9France Arvalis 228Route de l'Aérodrome-CS 4050984914 Avignon Cedex 9France International Field Phenomics Research Laboratory Institute for Sustainable Agro-Ecosystem ServicesGraduate School of Agricultural and Life SciencesThe University of TokyoTokyoJapan

Early-stage plant density is an essential trait that determines the fate of a genotype under given environmental conditions and management *** use of RGB images taken from UAVs may replace the traditional visual counting in fields with improved throughput,accuracy,and access to plant ***,high-resolution images are required to detect the small plants present at the early *** study explores the impact of image ground sampling distance(GSD)on the performances of maize plant detection at three-to-five leaves stage using Faster-RCNN object detection *** collected at high resolution(GSD≈0:3 cm)over six contrasted sites were used for model *** additional sites with images acquired both at high and low(GSD≈0:6 cm)resolutions were used to evaluate the model *** show that Faster-RCNN achieved very good plant detection and counting(rRMSE=0:08)performances when native high-resolution images are used both for training and ***,good performances were observed(rRMSE=0:11)when the model is trained over synthetic low-resolution images obtained by downsampling the native training high-resolution images and applied to the synthetic low-resolution validation ***,poor performances are obtained when the model is trained on a given spatial resolution and applied to another spatial *** on a mix of high-and low-resolution images allows to get very good performances on the native high-resolution(rRMSE=0:06)and synthetic low-resolution(rRMSE=0:10)***,very low performances are still observed over the native low-resolution images(rRMSE=0:48),mainly due to the poor quality of the native low-resolution ***,an advanced super resolution method based on GAN(generative adversarial network)that introduces additional textural information derived from the native high-resolution images was applied to the native low-resolution validation *** show some signi

关键词： RCNN Faster Image

LiDAR Is Effective in Characterizing Vine Growth and Detecting Associated Genetic Loci

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Plant Phenomics 2023年第4期5卷 836-851页

作者： Elsa Chedid Komlan Avia Vincent Dumas Lionel Ley Nicolas Reibel Gisèle Butterlin Maxime Soma Raul Lopez-Lozano Frédéric Baret Didier Merdinoglu Éric Duchêne INRAE University of StrasbourgUMR SVQV28rue de Herrlisheim68000 ColmarFrance INRAE UEAV28rue de Herrlisheim68000 ColmarFrance INRAE Aix-Marseille UniversitéUMR RECOVER3275 Route de Cézanne13182 Aix-en-ProvenceFrance INRAE Avignon UniversitéUMR EMMAHUMT CAPTE228route de l'aérodrome84914 AvignonFrance

The strong societal demand to reduce pesticide use and adaptation to climate change challenges the capacities of phenotyping new varieties in the ***-throughput phenotyping is a way to obtain meaningful and reliable information on hundreds of genotypes in a limited *** evaluated traits related to growth in 209 genotypes from an interspecific grapevine biparental cross,between IJ119,a local genitor,and Divona,both in summer and in winter,using several methods:fresh pruning wood weight,exposed leaf area calculated from digital images,leaf chlorophyll concentration,and LiDAR-derived apparent *** high-density genetic information obtained by the genotyping by sequencing technology(GBS),we detected 6 regions of the grapevine genome[quantitative trait loci(QTL)]associated with the variations of the traits in the *** detection of statistically significant QTLs,as well as correlations(R^(2))with traditional methods above 0.46,shows that LiDAR technology is effective in characterizing the growth features of the *** calculated with LiDAR-derived total canopy and pruning wood volumes were high,above 0.66,and stable between growing *** variables provided genetic models explaining up to 47%of the phenotypic variance,which were better than models obtained with the exposed leaf area estimated from images and the destructive pruning weight *** results highlight the relevance of LiDAR-derived traits for characterizing genetically induced differences in grapevine growth and open new perspectives for high-throughput phenotyping of grapevines in the vineyard.

关键词： LiDAR traits hundreds

Ageing evaluation of cable insulations subjected to radiation ageing:Application of principal component analyses to Fourier Transform Infra-Red and dielectric spectroscopy

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High Voltage 2022年第4期7卷 652-665页

作者： Simone Vincenzo Suraci Sandrine Amat Lea Hippolyte Astrid Malechaux Davide Fabiani Claire Le Gall Océane Juan Nathalie Dupuy LIMES Department of ElectricalElectronic and Information EngineeringUniversity of BolognaBolognaItaly Aix Marseille university Avignon UniversitéCNRSMarseilleFrance Institut de Radioprotection et de Sûreté Nucléaire MarseilleFrance

The evolution of properties of crosslinked polyethylene(XLPE)-based insulating mate-rials under radio-chemical ageing conditions is presented and *** total,seven different polymer compounds were tested,characterised by an increasing quantity of additives,for example,antioxidants(AOs)and fillers as flame *** were analysed using different testing techniques,that is,Fourier Transform Infra-Red and dielectric *** allowed a broad characterisation of the polymer,bringing to good correlations between the arising of new chemical groups caused by ageing and the modifications on the complex ***-based AOs are found to be the most efficient in terms of protection against *** the contrary,flame retardants are concluded not to have any impact on the material *** data were then treated using the principal component *** data treatment successfully distinguished the material composition(with and without additives)and the ageing *** results confirm the relevance of this analysis in understanding the impact of irradiation on the chemical and functional properties of the polymer materials studied.

关键词： component principal bringing

Global Wheat Head Detection Challenges:Winning Models and Application for Head Counting

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Plant Phenomics 2023年第3期5卷 460-473页

作者： Etienne David Franklin Ogidi Daniel Smith Scott Chapman Benoit de Solan Wei Guo Frederic Baret Ian Stavness UMR 1114 EMMAH INRAEAvignonFrance Arvalis–Institut du Végétal ParisFrance Department of Computer Science University of SaskatchewanSaskatoonCanada School of Food and Agricultural Sciences University of QueenslandBrisbaneAustralia Graduate School of Agricultural and Life Sciences The University of TokyoTokyoJapan

Data competitions have become a popular approach to crowdsource new data analysis methods for general and specialized data science *** competitions have a rich history in plant phenotyping,and new outdoor field datasets have the potential to embrace solutions across research and commercial *** developed the Global Wheat Challenge as a generalization competition in 2020 and 2021 to find more robust solutions for wheat head detection using field images from different *** analyze the winning challenge solutions in terms of their robustness when applied to new *** found that the design of the competition had an influence on the selection of winning solutions and provide recommendations for future competitions to encourage the selection of more robust solutions.

关键词： Wheat specialized competition

Azoximer bromide and hydroxyapatite:promising immune adjuvants in cancer

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Cancer Biology & Medicine 2023年第12期20卷 1021-1034页

作者： Jean-François Rossi Patrick Frayssinet Maksim Matciyak Nikolai Tupitsyn Institut du Cancer avignon-Provence Sainte Catherine–Department of Hematology-BiotherapyAvignon 84918France university of Montpellier UFR MédecineMontpellier 34090France HASTIM Inc. Rue de CauletToulouse 31300France Petrovax NPO Pharm Moscow 123112Russia Laboratory of Immunology of Hematopoiesis N.N.Blokhin Cancer Research Center(RCRC)Moscow 123112Russia

Immune adjuvants are immune modulators that have been developed in the context of infectious *** is currently a growing interest in immune adjuvants due to the development of immunotherapy against *** adjuvant mechanisms of action are focused on the initiation and amplification of the inflammatory response leading to the innate immune response,followed by the adaptive immune *** main activity lies in the support of antigen presentation and the maturation and functions of dendritic *** immune adjuvants are associated with a vaccine or incorporated into the new generation of m RNA *** immune adjuvants are used as ***(HA)ceramics and azoximer bromide(AZB)are overlooked molecules that were used in early clinical trials,which demonstrated clinical efficacy and excellent tolerance *** combined in an autologous vaccine was previously developed in the veterinary field for use in canine spontaneous ***,an original immune modulator derived from a class of heterochain aliphatic polyamines that is licensed in Russia,the Commonwealth of Independent States,and Slovakia for infectious and inflammatory diseases,is and now being developed for use in cancer with promising *** two immune adjuvants can be combined in various immunotherapy strategies.

关键词： Immune adjuvants cancer azoximer bromide hydroxyapatite Toll receptor agonists immunotherapy