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Structural Health Monitoring by Accelerometric Data of a Continuously Monitored Structure with Induced Damages

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Structural Durability & Health Monitoring 2024年第6期18卷 739-762页

作者： Giada Faraco Andrea Vincenzo De Nunzio Nicola Ivan Giannoccaro Arcangelo Messina Department of Innovation Engineering University of SalentoLecce73100Italy

The possibility of determining the integrity of a real structure subjected to non-invasive and non-destructive monitoring,such as that carried out by a series of accelerometers placed on the structure,is certainly a goal of extreme and current *** the present work,the results obtained from the processing of experimental data of a real structure are *** analyzed structure is a lattice structure approximately 9 m high,monitored with 18 uniaxial accelerometers positioned in pairs on 9 different *** data used refer to continuous monitoring that lasted for a total of 1 year,during which minor damage was caused to the structure by alternatively removing some bracings and repositioning them in the *** methodologies detecting damage based on decomposition techniques of the acquired data were used and tested,as well as a methodology combining the two *** results obtained are extremely interesting,as all the minor damage caused to the structure was identified by the processing methods used,based solely on the monitored data and without any knowledge of the real structure being *** results use 15 acquisitions in environmental conditions lasting 10 min each,a reasonable amount of time to get immediate feedback on possible damage to the structure.

关键词： Structural health monitoring damage detection vibration measurements stochastic subspace identification

Antisense therapy:a potential breakthrough in the treatment of neurodegenerative diseases

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Neural Regeneration Research 2024年第5期19卷 1027-1035页

作者： Roberta Romano Cecilia Bucci Department of Biological and Environmental Sciences and Technologies(DiSTeBA) University of SalentoLecceItaly

Neurodegenerative diseases are a group of disorders characterized by the progressive degeneration of neurons in the central or peripheral nervous ***,there is no cure for neurodegenerative diseases and this means a heavy burden for patients and the health system ***,it is necessary to find new therapeutic approaches,and antisense therapies offer this possibility,having the great advantage of not modifying cellular genome and potentially being *** preclinical and clinical studies aim to test the safety and effectiveness of antisense therapies in the treatment of neurodegenerative *** objective of this review is to summarize the recent advances in the development of these new technologies to treat the most common neurodegenerative diseases,with a focus on those antisense therapies that have already received the approval of the *** and Drug Administration.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis antisense oligonucleotide Huntington’s disease neurodegenerative disorders Parkinson’s disease siRNA

Effects of freeze-thaw cycles on sandstone in sunny and shady slopes

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2503-2515页

作者： Dian Xiao Xiaoyan Zhao Corrado Fidelibus Roberto Tomás Qiu Lu Hongwei Liu Academy of Railway Sciences Corporation Limited BeijingChina Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduChina Department of Civil Engineering University of AlicanteAlicanteSpain Department of Innovation Engineering University of SalentoLecceItaly Department of Earth and Environmental Sciences University of Milano BicoccaMilanItaly

A growing rock engineering activity in cold regions is facing the threat of freeze-thaw(FT)weathering,especially in high mountains where the sunny-shady slope effects strongly control the difference in weathering behavior of *** this paper,an investigation of the degradation of petrophysical characteristics of sandstone specimens subjected to FT cycle tests to simulate the sunny-shady slope effects is *** this aim,non-destructive and repeatable testing techniques including weight,ultrasonic waves,and nuclear magnetic resonance methods on standard specimens were *** the sunny slope specimens,accompanied by the enlargement of small pores,100 FT cycles caused a significant decrease in P-wave velocity with an average of 23%,but a consistent rise of 0.18%in mass loss,34%in porosity,67%in pore geometrical mean radius,and a remarkable 14.5-fold increase in ***,slight changes with some abnormal trends in physical parameters of the shady slope specimens were observed during FT cycling,which can be attributed to superficial granular disaggregation and pore throat *** shocks enhance rock weathering on sunny slopes during FT cycles,while FT weathering on shady slopes is restricted to the small pores and the superficial *** two factors are primarily responsible for the differences in FT weathering intensity between sunny and shady *** conclusions derived from the interpretation of the experimental results may provide theoretical guidance for the design of slope-failure prevention measures and the selection of transportation routes in cold mountainous regions.

关键词： Sunny-shady slope Freeze and thaw Pore structure Tight rocks Talus slope Cold regions

Highly sensitive ratiometric fluorescent fiber matrices for oxygen sensing with micrometer spatial resolution

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Bio-Design and Manufacturing 2024年第3期7卷 292-306页

作者： Giuliana Grasso Valentina Onesto Stefania Forciniti Eliana D’Amone Francesco Colella Lara Pierantoni Valeria Famà Giuseppe Gigli Rui L.Reis J.Miguel Oliveira Loretta L.del Mercato nstitute of Nanotechnology National Research Council(CNR-NANOTEC)c/o Campus Ecoteknevia Monteroni73100 LecceItaly Department of Mathematics and Physics“Ennio De Giorgi” University of Salentoc/o Campus Ecoteknevia Monteroni73100 LecceItaly 3B’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3B’s-PT Government Associate Laboratory 4806-909 Braga/GuimarãesPortugal Department of Experimental Medicine University of Salentoc/o Campus Ecoteknevia Monteroni73100 LecceItaly

Oxygen(O_(2))-sensing matrices are promising tools for the live monitoring of extracellular O_(2) consumption levels in long-term cell *** this study,ratiometric O_(2)-sensing membranes were prepared by electrospinning,an easy,low-cost,scalable,and robust method for fabricating ***(ε-caprolactone)and poly(dimethyl)siloxane polymers were blended with tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II)dichloride,which was used as the O_(2)-sensing probe,and rhodamine B isothiocyanate,which was used as the reference *** functionalized scaffolds were morphologically characterized by scanning electron microscopy,and their physicochemical profiles were obtained by Fourier transform infrared spectroscopy,thermogravimetric analysis,and water contact angle *** sensing capabilities were investigated by confocal laser scanning microscopy,performing photobleaching,reversibility,and calibration curve studies toward different dissolved O_(2)(DO)*** sensing nanofibers showed a high response to changes in DO concentrations in the physiological-pathological range from 0.5%to 20%and good stability under ratiometric *** addition,the sensing systems were highly biocompatible for cell growth promoting adhesiveness and growth of three cancer cell lines,namely metastatic melanoma cell line SK-MEL2,breast cancer cell line MCF-7,and pancreatic ductal adenocarcinoma cell line Panc-1,thus recreating a suitable biological environment in *** O_(2)-sensing biomaterials can potentially measure alterations in cell metabolism caused by changes in ambient O_(2)content during drug testing/validation and tissue regeneration processes.

关键词： Electrospinning Ruthenium(II)dichloride Oxygen sensors Ratiometric imaging Fluorescence

Yan Theorem in L~∞ with Applications to Asset Pricing

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Acta Mathematicae Applicatae Sinica 2007年第4期23卷 551-562页

作者： Gianluca Cassese university of Lugano via G.Buffi 13CH-6904 LuganoSwitzerland and Università del Salento

We prove an L∞ version of the Yan theorem and deduce from it a necessary condition for the absence of free lunches in a model of financial markets, in which asset prices are a continuous R^d valued process and only simple investment strategies are admissible. Our proof is based on a new separation theorem for convex sets of finitely additive measures.

关键词： Arbitrage free lunch fundamental theorem of asset pricing martingale measure Yan theorem

Inverse full state hybrid projective synchronization for chaotic maps with different dimensions

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Chinese Physics B 2016年第9期25卷 251-256页

作者： Adel Ouannas Giuseppe Grassi Laboratory of Mathematics Informatics and Systems (LAMIS) University of Larbi Tebessi Tebessa 12002 Algeria university del salento Dipartimento Ingegneria Innovazione 73100 Lecce Italy

A new synchronization scheme for chaotic（hyperchaotic） maps with different dimensions is ***,given a drive system map with dimension n and a response system with dimension m,the proposed approach enables each drive system state to be synchronized with a linear response combination of the response system *** method,based on the Lyapunov stability theory and the pole placement technique,presents some useful features：（i） it enables synchronization to be achieved for both cases of n 〈 m and n 〉 m;（ii） it is rigorous,being based on theorems;（iii） it can be readily applied to any chaotic（hyperchaotic） maps defined to ***,the capability of the approach is illustrated by synchronization examples between the two-dimensional H′enon map（as the drive system） and the three-dimensional hyperchaotic Wang map（as the response system）,and the three-dimensional H′enon-like map（as the drive system） and the two-dimensional Lorenz discrete-time system（as the response system）.

关键词： chaotic map full state hybrid projective synchronization inverse problem maps with different dimensions

River bank protection from ship-induced waves and river flow

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Water Science and Engineering 2019年第2期12卷 129-135页

作者： Sahameddin Mahmoudi Kurdistani Giuseppe R. Tomasicchin Felice D’Alessandro Leila Hassanabadi Department of Engineering for Innovation University of Salento

A new equation is proposed for the design of armor units on protected river banks under the combined action of ship-induced waves and river *** observed field and experimental data in the literature have been examined and a valuable database has been *** conditions,including the river water depth,flow velocity,river bank slope,Froude number,wave height,wave period,and wave obliquity have been *** from an empirical equation (Bhowmik,1978) that only considers the maximum wave height and river bank slope have been compared with the results calculated by the newly developed *** results have also been verified against field *** show that not only the maximum wave height and river bank slope but also the water depth,flow velocity,wave length,wave obliquity,and wave period are important parameters for predicting the mean diameter of the armor units,highlighting the multivariate behavior of protecting the river bank in the presence of ship-induced waves and river flow velocity.

关键词： River bank protection Hydraulics Ship-induced waves River flow velocity Wave period Wave obliquity Multivariate phenomenon

Dinophysoid dinoflagellates from subphotic depths:Amphisolenia ***,Dinofurcula tricornuta ***.,and Dinophysis profunda ***.(Dinophysales,Dinophyceae)

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Journal of Oceanology and Limnology 2022年第2期40卷 703-711页

作者： Fernando GÓMEZ Department of Biological and Environmental Sciences and Technologies University of SalentoLecce 73100Italy

Three species of dinophysoid planktonic dinoflagellates are described from the eastern Mediterranean *** *** was collected at 70-m depth in the Ionian *** small species showed a more asymmetric midbody and a proportionally longer neck when compared to the closer relative *** individuals of Dinofurcula tricornuta *** at 154-m depth in the Marmara Sea are characterized by three posterior-oriented processes when compared to its congeneric *** is the first record of the genus Dinofurcula beyond the eastern tropical Pacific *** profunda *** at 500-m depth in the Ionian Sea is characterized by ovate hypotheca and a serrate crest-like left sulcal list when compared to its close relative *** findings evidence an undescribed biodiversity in the under-sampled subphotic depths.

关键词： deep ocean Dinophyta Dinoflagellata Mediterranean Sea mesopelagic new species

Static Analysis of Anisotropic Doubly-Curved Shell Subjected to Concentrated Loads Employing Higher Order Layer-Wise Theories

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Computer Modeling in Engineering & Sciences 2023年第2期134卷 1393-1468页

作者： Francesco Tornabene Matteo Viscoti Rossana Dimitri Department of Innovation Engineering School of EngineeringUniversity of SalentoLecce73100Italy

In the presentmanuscript,a Layer-Wise(LW)generalizedmodel is proposed for the linear static analysis of doublycurved shells constrained with general boundary conditions under the influence of concentrated and surface *** unknown field variable is modelled employing polynomials of various orders,each of them defined within each layer of the *** a particular case of the LW model,an Equivalent Single Layer(ESL)formulation is derived *** approaches are outlined for the assessment of external forces,as well as for non-conventional *** doubly-curved shell is composed by superimposed generally anisotropic laminae,each of them characterized by an arbitrary *** fundamental governing equations are derived starting from an orthogonal set of principal ***,generalized blending functions account for the distortion of the physical *** implementation of the fundamental governing equations is performed bymeans of the Generalized Differential Quadrature(GDQ)method,whereas the numerical integrations are computed employing theGeneralized IntegralQuadrature(GIQ)*** the post-processing phase,an effective procedure is adopted for the reconstruction of stress and strain through-the-thickness distributions based on the exact fulfillment of three-dimensional equilibrium equations.A series of systematic investigations are performed in which the static response of structures with various curvatures and lamination schemes,calculated by the present methodology,have been successfully compared to those ones obtained fromrefined finite element three-dimensional *** though the present LW approach accounts for a two-dimensional assessment of the structural problem,it is capable of well predicting the three-dimensional response of structures with different characteristics,taking into account a reduced computational cost and pretending to be a valid alternative to widespread numerical implementations.

关键词： Concentrated load doubly-curved shells generalized differential quadrature laminated anisotropic materials layer-wise theory mapping technique