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Women health and microbiota:Different aspects of well-being

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World Journal of Gastroenterology 2024年第10期30卷 1287-1290页

作者： Giulia Nannini Amedeo Amedei Department of Experimental and Clinical Medicine University of FlorenceFlorence 50134Italy network of Immunity in Infection Malignancy and Autoimmunity(NIIMA)Universal Scientific Education and Research Network(USERN)Florence 50134Italy

In this editorial,we comment on the article by Marano et al recently published in the World Journal of Gastroenterology 2023;29(45):*** focus on the role of gut microbiota(GM)in women’s health,highlighting the need to thoroughly comprehend the sex differences in ***,the host and GM support the host’s *** microbiota components consist of viruses,bacteria,fungi,and *** complex is an essential part of the host and is involved in neu-rological development,metabolic control,immune system dynamics,and host dynamic *** has been shown that differences in the GM of males and females can contribute to chronic diseases,such as gastrointestinal,metabolic,neurological,cardiovascular,and respiratory *** differences can also result in some sex-specific changes in *** day,research on GM reveals new and more expansive frontiers,offering a wealth of innovative oppor-tunities for preventive and precision medicine.

关键词： Gut microbiota Women Immune system Well-being Hormones Sexdifferences

Physical Layer Encryption of OFDM-PON Based on Quantum Noise Stream Cipher with Polar Code

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China Communications 2024年第3期21卷 174-188页

作者： Xu Yinbo Gao Mingyi Zhu Huaqing Chen Bowen Xiang Lian Shen Gangxiang Jiangsu Engineering Research Center of Novel Optical Fiber Technology and Communication network Suzhou Key Laboratory of Advanced Optical Communication Network Technologythe School of Electronic and Information EngineeringSoochow UniversityNo.1 Shizi StreetSuzhou 215006China

Orthogonal frequency division multiplexing passive optical network(OFDM-PON) has superior anti-dispersion property to operate in the C-band of fiber for increased optical power budget. However,the downlink broadcast exposes the physical layer vulnerable to the threat of illegal eavesdropping. Quantum noise stream cipher(QNSC) is a classic physical layer encryption method and well compatible with the OFDM-PON. Meanwhile, it is indispensable to exploit forward error correction(FEC) to control errors in data transmission. However, when QNSC and FEC are jointly coded, the redundant information becomes heavier and thus the code rate of the transmitted signal will be largely reduced. In this work, we propose a physical layer encryption scheme based on polar-code-assisted QNSC. In order to improve the code rate and security of the transmitted signal, we exploit chaotic sequences to yield the redundant bits and utilize the redundant information of the polar code to generate the higher-order encrypted signal in the QNSC scheme with the operation of the *** experimentally demonstrate the encrypted 16/64-QAM, 16/256-QAM, 16/1024-QAM, 16/4096-QAM QNSC signals transmitted over 30-km standard single mode fiber. For the transmitted 16/4096-QAM QNSC signal, compared with the conventional QNSC method, the proposed method increases the code rate from 0.1 to 0.32 with enhanced security.

关键词： physical layer encryption polar code quantum noise stream cipher

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A cross-sectional analysis of the effectiveness of a nutritional support programme for people with tuberculosis in Southern Madagascar using secondary data from a non-governmental organisation

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Infectious Diseases of Poverty 2024年第1期13卷 101-102页

作者： Mara Anna Franke Julius Valentin Emmrich Fierenantsoa Ranjaharinony Onja GbrilleRavololohanitra Harizaka Emmanuel Andriamasy Samuel Knauss Nadine Muller Global Digital health Lab at Charité Center for Global health Charité – Universitätsmedizin Berlin Berlin Germany London School of Hygiene and Tropical Medicine London UK Ärzte Für Madagaskar E.V. Leipzig Germany Heidelberg Institute of Global health Heidelberg University Heidelberg Germany Berlin Institute of health at Charité - Universitätsmedizin Berlin Berlin Germany Doctors for Madagascar Antananarivo Madagascar Speciality network: Infectious Diseases and Respiratory Medicine Charité - Universitätsmedizin Berlin Berlin Germany

Background There is a strong,bi-directional link between tuberculosis(TB)and undernutrition:TB often causes undernutrition,and undernourished people are more likely to contract TB and experience worse ***,several TB nutritional support programmes exist;however,evidence on their effectiveness is limited and *** study evaluates the effect of a nutritional support programme implemented for people with TB in the Atsimo-Andrefana region,Madagascar in *** this programme,undernourished people with TB[with a body mass index(BMI)of<18.5 kg/m]receive 0.6 L of vegetable oil and 6.0 kg of a soy-wheat blend per month throughout their TB *** We analysed secondary non-governmental organisation data collected between January and Novem-ber 2022 in the Atsimo-Andrefana region,Southern Madagascar,including information on an individual's medical conditions(e.g.,type of TB,treatment outcomes)and nutritional status measured prior to,during,and after comple-tion of treatment(e.g.,height,weight,mid-upper arm circumference).We conducted descriptive analyses of patient baseline characteristics and outcomes to assess the impact of the provided nutritional support on the BMI of people With *** A total of 1310 people with TB were included in the study[9.9%(130)children under the age of 5,32.1%(420)children between 5 and 18 years,58.0%(760)adults].55.4% of children under 5,28.1% of children between ages 5 and 18,and 81.3%of adults were undernourished at treatment initiation.42.3%(55/130)of children under 5 experi-enced severe acute malnutrition at treatment *** the average BMl of adults with TB receiving food support increased over time,from 17.1 kg/m^(2)(interquartile range:15.8-18.3,range:10.3-22.5)to 17.9 kg/m^(2)(interquartile range:16.6-19.1,range:11.9-24.1),most adults remained undernourished even after completing TB *** The current TB nutritional support programme falls short of sufficiently increasing the BM

关键词： Tuberculosis Sub-Saharan Africa Undernutrition Nutritional support

Method and Practice of Trusted Embedded Computing and Data Transmission Protection Architecture Based on Android

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Chinese Journal of Electronics 2024年第3期33卷 623-634页

作者： Yichuan WANG Wen GAO Xinhong HEI Yanning DU School of Computer Science and Engineering Xi'an University of Technology Shaanxi Key Laboratory for network Computing and Security Technology

In recent years,the rapid development of Internet technology has constantly enriched people's daily life and gradually changed from the traditional computer terminal to the mobile *** with it comes the security problems brought by the mobile *** for Android system,due to its open source nature,malicious applications continue to emerge,which greatly threatens the data security of ***,this paper proposes a method of trusted embedded static measurement and data transmission protection architecture based on Android to reduce the risk of data leakage in the process of terminal storage and *** conducted detailed data and feasibility analysis of the proposed method from the aspects of time consumption,storage overhead and *** experimental results show that this method can detect Android system layer attacks such as self-booting of the malicious module and improve the security of data encryption and transmission process *** with the native system,the additional performance overhead is small.

关键词： Embedded computing Protocols Data security Computer architecture Encryption Internet Data communication

Resonant Beam Communications:A New Design Paradigm and Challenges

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Journal of Communications and Information networks 2024年第1期9卷 80-87页

作者： Yuanming Tian Dongxu Li Chuan Huang Qingwen Liu Shengli Zhou Future network of Intelligence Institute and School of Science and Engineering the Chinese University of Hong KongShenzhen 518172China School of Science and Engineering and the Future network of Intelligence Institute the Chinese University of Hong KongShenzhen 518172China College of Electronics and Information Engineering Tongji UniversityShanghai 201804China Department of Electrical and Computer Engineering University of ConnecticutStorrsCT 06250USA

Resonant beam communications (RBCom), which adopts oscillating photons between two separate retroreflectors for information transmission, exhibits potential advantages over other types of wireless optical communications (WOC). However, echo interference generated by the modulated beam reflected from the receiver affects the transmission of the desired information. To tackle this challenge, a synchronization-based point-to-point RBCom system is proposed to eliminate the echo interference, and the design for the transmitter and receiver is discussed. Subsequently,the performance of the proposed RBCom is evaluated and compared with that of visible light communications(VLC)and free space optical communications (FOC). Finally, future research directions are outlined and several implementation challenges of RBCom systems are highlighted.

关键词： resonant beam communications(RBCom) wireless optical communications(WOC) echo interference elimination mobility multiple access

Multimodal fusion recognition for digital twin

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Digital Communications and networks 2024年第2期10卷 337-346页

作者： Tianzhe Zhou Xuguang Zhang Bing Kang Mingkai Chen Key Laboratory of Broadband Wireless Communication and Sensor network Technology Ministry of EducationNanjing University of Posts and TelecommunicationsNanjing210003China

The digital twin is the concept of transcending reality,which is the reverse feedback from the real physical space to the virtual digital *** hold great prospects for this emerging *** order to realize the upgrading of the digital twin industrial chain,it is urgent to introduce more modalities,such as vision,haptics,hearing and smell,into the virtual digital space,which assists physical entities and virtual objects in creating a closer ***,perceptual understanding and object recognition have become an urgent hot topic in the digital *** surface material classification schemes often achieve recognition through machine learning or deep learning in a single modality,ignoring the complementarity between multiple *** order to overcome this dilemma,we propose a multimodal fusion network in our article that combines two modalities,visual and haptic,for surface material *** the one hand,the network makes full use of the potential correlations between multiple modalities to deeply mine the modal semantics and complete the data *** the other hand,the network is extensible and can be used as a universal architecture to include more *** show that the constructed multimodal fusion network can achieve 99.42%classification accuracy while reducing complexity.

关键词： Digital twin Multimodal fusion Object recognition Deep learning Transfer learning

Optimal Stochastic Scheduling Strategy of Multi-vector Energy Complex Integrated with Full-blown Power-to-biomethane Model

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 863-873页

作者： Guanwei Zeng Chengxi Liu Minfang Liao Yongjian Luo Xuzhu Dong Hubei Engineering and Technology Research Center for AC/DC Intelligent Distribution network WuhanChina the School of Electrical Engineering and Automation Wuhan UniversityWuhanChina

We propose an optimal stochastic scheduling strategy for a multi-vector energy complex(MEC),considering a fullblown model of the power-to-biomethane(Pt M)*** conventional optimization that uses a simple efficiency coefficient to coarsely model energy conversion between electricity and biomethane,a detailed Pt M model is introduced to emphasize the reactor kinetics and chemical equilibria of *** model crystallizes the interactions between the Pt M process and MEC flexibility,allowing to adjust the operating condition of the methanation reactor for optimal MEC operation in stochastic *** optimization and flowsheet design of the Pt M process increase the average selectivity of methane(i.e.,ratio between net biomethane production and hydrogen consumption)up to 83.7%in the proposed synthesis *** results can provide information and predictions to operators about the optimal operating conditions of a Pt M unit while improving the MEC flexibility.

关键词： Multi-vector energy complex optimal stochastic scheduling power-to-biomethane unit process synthesis natural gas

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Bispecific antibody drug conjugates:Making 1+1>2

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Acta Pharmaceutica Sinica B 2024年第5期14卷 1965-1986页

作者： Yilin Gu Zhijia Wang Yuxi Wang Targeted Tracer Research and Development Laboratory Institute of Respiratory HealthFrontiers Science Center for Disease-Related Molecular NetworkNational Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengdu 610041China Frontiers Medical Center Tianfu Jincheng LaboratoryChengdu 610212China

Bispecific antibody‒drug conjugates(BsADCs)represent an innovative therapeutic category amalgamating the merits of antibody‒drug conjugates(ADCs)and bispecific antibodies(BsAbs).Positioned as the next-generation ADC approach,BsADCs hold promise for ameliorating extant clinical challenges associated with ADCs,particularly pertaining to issues such as poor internalization,off-target toxicity,and drug ***,ten BsADCs are undergoing clinical trials,and initial findings underscore the imperative for ongoing *** review initially delves into specific design considerations for BsADCs,encompassing target selection,antibody formats,and the linker–payload *** sections delineate the extant progress and challenges encountered by BsADCs,illustrated through pertinent case *** amalgamation of BsAbs with ADCs offers a prospective solution to prevailing clinical limitations of ***,the symbiotic interplay among BsAb,linker,and payload necessitates further optimizations and coordination beyond a simplistic“1+1”to effectively surmount the extant challenges facing the BsADC domain.

关键词： Bispecific antibody drug conjugates Antibody drug conjugates Bispecific antibody Targeted therapy Safety HER2 EGFR

A New Encrypted Traffic Identification Model Based on VAE-LSTM-DRN

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Computers, Materials & Continua 2024年第1期78卷 569-588页

作者： Haizhen Wang Jinying Yan Na Jia College of Computer and Control Engineering Qiqihar UniversityQiqihar161006China Heilongjiang Key Laboratory of Big Data network Security Detection and Analysis Qiqihar UniversityQiqiharChina

Encrypted traffic identification pertains to the precise acquisition and categorization of data from traffic datasets containing imbalanced and obscured *** extraction of encrypted traffic attributes and their subsequent identification presents a formidable *** existing models have predominantly relied on direct extraction of encrypted traffic data from imbalanced datasets,with the dataset’s imbalance significantly affecting the model’s *** the present study,a new model,referred to as UD-VLD(Unbalanced Dataset-VAE-LSTM-DRN),was proposed to address above *** proposed model is an encrypted traffic identification model for handling unbalanced *** encoder of the variational autoencoder(VAE)is combined with the decoder and Long-short term Memory(LSTM)in UD-VLD model to realize the data enhancement processing of the original unbalanced *** enhanced data is processed by transforming the deep residual network(DRN)to address neural network gradient-related ***,the data is classified and *** UD-VLD model integrates the related techniques of deep learning into the encrypted traffic recognition technique,thereby solving the processing problem for unbalanced *** UD-VLD model was tested using the publicly available Tor dataset and VPN *** UD-VLD model is evaluated against other comparative models in terms of accuracy,loss rate,precision,recall,F1-score,total time,and ROC *** results reveal that the UD-VLD model exhibits better performance in both binary and multi classification,being higher than other encrypted traffic recognition models that exist for unbalanced ***,the evaluation performance indicates that the UD-VLD model effectivelymitigates the impact of unbalanced data on traffic *** can serve as a novel solution for encrypted traffic identification.

关键词： Data enhancement LSTM deep residual network VAE