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Chaos generator for secure transmission using a sine map and an RLC series circuit

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Science China(Information Sciences) 2010年第1期53卷 129-136页

作者： CHARG Pascal FOURNIER-PRUNARET Danièle TAHA Abdel-Kaddous LATTIS EA no.4155 INSAToulouse University135 avenue de Rangueil 31077 Toulouse Cedex 4France

This paper deals with the model analysis of a chaos generator for secure transmission. In this proposed system discrete value signals and continuous value signals are used together and are interacting one another. The main advantage of this system is that a discrete chaotic map can be implemented in the digital circuit with many parameters, and initial condition can be set with a great accuracy. Also, the problem of periodicity which is always encountered in any fully discrete systems can be avoided. A chaotic behavior study of the system is then provided, in which bifurcation phenomena are explained and chaotic attractors are shown. Finally, an asymptotic chaotic behavior of the proposed system is derived.

关键词： chaos generator nonlinear map hybrid circuit secure transmission

A cost driven predictive maintenance policy for structural airframe maintenance

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Chinese Journal of Aeronautics 2017年第3期30卷 1242-1257页

作者： Yiwei WANG Christian GOGU Nicolas BINAUD Christian BES Raphael T.HAFTKA Nam H.KIM universite de toulouse INSA/UPS/ISAE/Mines Albi ICA UMR CNRS 5312 Toulouse 31400 Frallce Department of Mechanical & Aerospace Engineering University of Florida Gainesville 32611 USA

Airframe maintenance is traditionally performed at scheduled maintenance *** decision to repair a fuselage panel is based on a fixed crack size threshold,which allows to ensure the aircraft safety until the next scheduled maintenance *** progress in sensor technology and data processing techniques,structural health monitoring（SHM） systems are increasingly being considered in the aviation *** systems track the aircraft health state continuously,leading to the possibility of planning maintenance based on an actual state of aircraft rather than on a fixed *** paper builds upon a model-based prognostics framework that the authors developed in their previous work,which couples the Extended Kalman filter（EKF） with a firstorder perturbation（FOP） *** using the information given by this prognostics method,a novel cost driven predictive maintenance（CDPM） policy is proposed,which ensures the aircraft safety while minimizing the maintenance *** proposed policy is formally derived based on the trade-off between probabilities of occurrence of scheduled and unscheduled maintenance.A numerical case study simulating the maintenance process of an entire fleet of aircrafts is *** the condition of assuring the same safety level,the CDPM is compared in terms of cost with two other maintenance policies：scheduled maintenance and threshold based SHM *** comparison results show CDPM could lead to significant cost savings.

关键词： Extended Kalman filter First-order perturbation method Model-based prognostic Predictive maintenance Structural airframe maintenance

Interleukin 7 regulates switch transcription in developing B cells

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Cellular & Molecular Immunology 2021年第3期18卷 776-778页

作者： Audrey Dauba Fatima-Zohra Braikia Chloe Oudinet Ahmed Amine Kham lichi Mnstitut de Pharmacologie et de Biologie Structurale IPBSUniversite de ToulouseCNRSUniversity Paul Sabatier31077 ToulouseFrance

Class switch recombination(CSR)enables activated mature B cells to change immunoglobulin(Ig)isotype expression from IgM to IgG,IgE,or *** process requires activation-induced cytidine deaminase(AID)expression and transcription of the target sequences at the Ig heavy chain(IgH)constant locus,which is composed of multiple constant(C_(H))genes,each specifying an Ig isotype.

关键词： Interleukin enable IgH

Degradation of PAI/PEI Enamel under High Temperature (Up to 400°C)

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Materials Sciences and Applications 2022年第1期13卷 1-21页

作者： Fabrice Aymonino Thierry Lebey David Malec Dominique Mary LAboratoire PlAsma et Conversion d’Energie (LAPLACE) Université de Toulouse Toulouse France

This work deals with the understanding of the degradation of the primary insulation (PEI/PAI) of rotating machines working temporarily under high-temperature. The main domain of application of these motors is the smoke extraction either from tunnels or underground parking when a fire occurs. In such a critical situation, the internal temperature of the motor winding may reach temperatures up to 400°C. Under such very high thermal stresses, the behaviour of the electrical insulation is not well understood. This work proposes an analysis of the decomposition gases under very high temperatures and the corresponding degradation pathway. A simple method is proposed to identify whether the insulation of such motors has been strongly damaged during the working time at very high temperatures, thus allowing estimating if it can still continue to operate.

关键词： Polyesterimide (PEI) Polyamide-Imide (PAI) Enamel Electrical Insulation Rotating Machine High Temperature Thermal Degradation

αV integrin:A new gastrin target in human pancreatic cancer cells

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World Journal of Gastroenterology 2011年第40期17卷 4488-4495页

作者： Celine Cayrol Claudine Bertrand Aline Kowalski-Chauvel Laurence Daulhac Elizabeth Cohen-Jonathan-Moyal Audrey Ferrand Catherine Seva INSERM UMR1037-Cancer Research Center of toulouse Paul Sabatier university toulouse Ⅲ 31432 Toulouse cedex 4 France INSERM U766 Department of pharma-cology Clermont 1 university of Pharmacy 63001 Clermont-Ferrand France

AIM： To analyse αv integrin expression induced by gas- trin in pancreatic cancer ***： αv integrin mRNA expression in human pan- creatic cancer cells was analysed using a ＂cancer genes＂ array and confirmed by real-time reverse transcription- polymerase chain reaction （PCR）. Western blotting and semi-quantitative immunohistochemistry were used to examine protein levels in human pancreatic cancer cell lines and pancreatic tissues, respectively, The role of αv integrin on gastrin-induced cell adhesion was examined using blocking anti-αv integrin monoclonal antibodies. Adherent cells were quantified by staining with crystal ***： Using a ＂cancer genes＂ array we identi- fied c^v integrin as a new gastrin target gene in human pancreatic cancer cells. A quantitative real-time PCR approach was used to confirm αv integrin gene expression. We also demonstrate that Src family kinases and the PI 3-kinase, two signalling pathways specifically activated by the CCK-2 receptor （CCK2R）, are involved in gastrin-mediated αv integrin expression. In contrast, inhibition of the ERK pathway was without any effect on αv integrin expression induced by gastrin. Our results also show that gastrin modulates cell adhesion via αv integrins. Indeed, in vitro adhesion assays performed on fibronectin show that gastrin significantly increases adhesion of pancreatic cancer cells. The use of blocking anti-αv integrin monoclonal antibodies completely reversed the increase in cell-substrate adhesion induced by gastrin. In addition, we showed in vivo that the targeted CCK2R expression in the pancreas of Elas-CCK2 mice, leads to the overexpression of αv integrin. This process may contribute to pancreatic turnout development observed in these transgenic ***： αv integrin is a new gastrin target in pancreatic cancer models and contributes to gastrin effects on cell adhesion.

关键词： v integrin Cell adhesion CCK-2 receptor Gastrin Pancreatic cancer

Tourism and Rural Heritage: A Win-Win Relation? The Conditions of Heritage Making in Touristic Rural Regions

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Built Heritage 2019年第2期3卷 24-36页

作者： Alain Bourdin Tingting Wan Philippe Delbos Lab'urba École d'urbanisme de ParisUniversitéde Paris-EstParisFrance LAVUE/CNRS UniversitéParis NanterreParisFrance Heritage Architect ToulouseFrance

The relationship between heritage and rural development takes place within the heritage making pro*** presents different characteristics of what exists in urban context,especially through the role that can play the built heritage in the reception of the *** study of the case of a French department,the Gers,characterised by an important intangible heritage linked to gastronomy and agriculture,but away from the major flows of mass tourism,reveals three major criteria for success:the importance of organising an actor’s network that gathers the world of local economy,tourism and heritage,in conjunction with local authorities;the existence of a strong legitimation structure that justifies these *** France it was developed from a scientific approach:that of rural ethnology;the inscription in a temporality which allows successive stages and which is as much that of the local development project as that of the patrimonial action itself.

关键词： heritagisation rural heritage local development intangible heritage cooperation heritage legitimation owners

Functionalized liposomes for targeted breast cancer drug delivery

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Bioactive Materials 2023年第6期24卷 401-437页

作者： Janske Nel Kamil Elkhoury Émilie Velot Arnaud Bianchi Samir Acherar Grégory Francius Ali Tamayol Stéphanie Grandemange Elmira Arab-Tehrany universitéde Lorraine LIBioF-54000NancyFrance LAAS-CNRS F-31400ToulouseFrance universitéde Lorraine CNRSIMoPAF-54000NancyFrance universitéde Lorraine CNRSLCPMF-54000NancyFrance universitéde Lorraine CNRSLCPMEF-54000NancyFrance Department of Biomedical Engineering University of Connecticut Health CenterFarmingtonCT06030USA universitéde Lorraine CNRSCRANF-54000NancyFrance

Despite the exceptional progress in breast cancer pathogenesis,prognosis,diagnosis,and treatment strategies,it remains a prominent cause of female mortality ***,although chemotherapies are effective,they are associated with critical limitations,most notably their lack of specificity resulting in systemic toxicity and the eventual development of multi-drug resistance(MDR)cancer *** have proven to be an invaluable drug delivery system but of the multitudes of liposomal systems developed every year only a few have been approved for clinical use,none of which employ active *** this review,we summarize the most recent strategies in development for actively targeted liposomal drug delivery systems for surface,transmembrane and internal cell receptors,enzymes,direct cell targeting and dual-targeting of breast cancer and breast cancer-associated cells,e.g.,cancer stem cells,cells associated with the tumor microenvironment,etc.

关键词： Liposomes Breast cancer Anti-cancer agents Targeted drug delivery Surface functionalization Receptor-targeted drug delivery

Oil and fatty acid accumulation during coriander (Coriandrum sativum L.) fruit ripening under organic cultivation

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The Crop Journal 2015年第4期3卷 366-369页

作者： Quang-Hung Nguyen Thierry Talou Mureil Cerny Philippe Evon Othmane Merah université Fédérale de toulouse Midi-Pyrénées INP-ENSIACET Laboratoire de Chimie Agro-industrielle Institut National de Recherche Agronomique UMR 1010 CAI

To evaluate the accumulation of oil and fatty acids in coriander during fruit ripening, a field experiment was conducted under organic cultivation conditions in Auch(near toulouse,southwestern France) during the 2009 cropping season. The percentage and composition of the fatty acids of coriander were determined by gas chromatography. Our results showed that rapid oil accumulation started in early stages(two days after flowering, DAF). Twelve fatty acids were identified. Saturated and polyunsaturated acids were the dominant fatty acids at earlier stages(2–12 DAF), but decreased after this date. After this stage,petroselinic acid increased to its highest amount at 18 DAF. In contrast, palmitic acid followed the opposite trend. Saturated and polyunsaturated fatty acids decreased markedly and monounsaturated fatty acids increased during fruit maturation. It appears that the fruit of coriander may be harvested before full maturity.

关键词： Oil content Petroselinic acid Coriander Organic cultivation Fatty acid accumulation

Numerical Approximation of Port-Hamiltonian Systems for Hyperbolic or Parabolic PDEs with Boundary Control

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Journal of Applied Mathematics and Physics 2021年第6期9卷 1278-1321页

作者： Andrea Brugnoli Ghislain Haine Anass Serhani Xavier Vasseur Robotics and Mechatronics Department University of Twente Enschede Netherlands ISAE-SUPAERO Université de Toulouse Toulouse France CERFACS Toulouse France

We consider the design of structure-preserving discretization methods for the solution of systems of boundary controlled Partial Differential Equations (PDEs) thanks to the port-Hamiltonian formalism. We first provide a novel general structure of infinite-dimensional port-Hamiltonian systems (pHs) for which the Partitioned Finite Element Method (PFEM) straightforwardly applies. The proposed strategy is applied to abstract multidimensional linear hyperbolic and parabolic systems of PDEs. Then we show that instructional model problems based on the wave equation, Mindlin equation and heat equation fit within this unified framework. Secondly, we introduce the ongoing project SCRIMP (Simulation and Control of Interactions in Multi-Physics) developed for the numerical simulation of infinite-dimensional pHs. SCRIMP notably relies on the FEniCS open-source computing platform for the finite element spatial discretization. Finally, we illustrate how to solve the considered model problems within this framework by carefully explaining the methodology. As additional support, companion interactive Jupyter notebooks are available.

关键词： Port-Hamiltonian Systems Partial Differential Equations Boundary Control Structure-Preserving Discretization Finite Element Method