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Morphometric evaluation of wound healing in burns treated with Ulmo (Eucryphia cordifolia) honey alone and supplemented with ascorbic acid in guinea pig (Cavia porcellus)

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Burns & Trauma 2016年第4期4卷 264-272页

作者： Carolina Schencke Adriana Vasconcellos Cristian Sandoval Paulina Torres Francisca Acevedo Mariano del Sol Doctoral Program in Morphological Sciences Universidad de La FronteraTemucoChile CONICYT-PCHA/National Doctorate Programme/2014-21141130 SantiagoChile Facultad de Medicina Universidad de La FronteraTemucoChile Doctoral Program in Morphological Sciences Universidad de La FronteraTemucoChile CIMA Research Group Facultad de OdontologíaUniversidad de La FronteraTemucoChile CONICYT-PCHA/Doctorado Nacional/2015-21150991 SantiagoChile Scientific and Technological Bioresource Nucleus Universidad de La FronteraTemucoChile Facultad de Medicina Universidad de La FronteraTemucoChile Centro de Excelencia en Estudios Morfológicos y Quirúrgicos(CEMyQ) Universidad de La FronteraTemucoChile Centro de Investigación en Ciencias Biomédicas Universidad Autónoma de ChileTemucoChile

Background:In the context of the search for cost-efficient treatments,Ulmo(Eurcyphia cordifolia)honey is an excellent alternative for treating burn wounds and could have a profound medical,social,and economic *** acid is an enzymatic co-factor necessary for the synthesis of collagen and the proliferation of fibroblasts and has been proposed as a coadjuvant to strengthen the healing effects of *** aim of this work was to evaluate by morphometric studies the healing wounds caused by burns treated with Ulmo honey alone and supplemented with ascorbic acid in guinea pig(Cavia porcellus).Methods:Fifteen guinea pigs were used and divided randomly into three groups:positive control(C+),experimental with unsupplemented honey(H),and experimental with supplemented honey(SH).A uniform deep burn covering 1 cm2of the back skin was *** following indices were calculated for the morphometric study:superficial contraction index of the wound,deep contraction index of the wound,wound severity index,global healing index,global contraction index,and dermal proliferation ***:The superficial contraction index of the wound,global healing index,global contraction,and dermal proliferation area values of the experimental with supplemented honey group were higher than the other groups(P<0.05).Conclusions:According to these results,the combination of honey with an antioxidant(ascorbic acid)promotes an appropriate action to support the healing *** study showed that by supplementing the Ulmo honey with ascorbic acid,the healing and contraction effects can be strengthened in burn wounds compared to unsupplemented *** results were proof of the synergy between honey and ascorbic acid in healing burn wounds.

关键词： Honey Ascorbic acid Burn Morphometry Wound healing

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Prevalence of gastroesophageal reflux disease:a population-based cross-sectional study in southern Chile

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Gastroenterology Report 2020年第4期8卷 286-292,I0001,I0002页

作者： Carlos Manterola Luis Grande Luis Bustos Tamara Otzen Center of Morphological and Surgical Studies Universidad de La FronteraTemucoChile department of Surgery Universidad de La FronteraTemucoChile department of Surgery Hospital del MarUniversitat Auto`noma de BarcelonaBarcelonaSpain department of Public Health Universidad de La FronteraTemucoChile

Background This study assessed the prevalence of gastroesophageal reflux disease(GERD)in a general adult population from temuco in southern *** association of GERD with demographic variables was also *** A cross-sectional study among the general population of temuco in southern Chile was conducted in 2017,using a validated and reliable questionnaire for detecting *** urban area of temuco,with a population of 245,317 inhabitants(2002 census),was divided into four zones,which were representative of the socioeconomic sectors of the *** sample size was estimated assuming a prevalence of 52.8%,an accuracy of 3.0%,a confidence level of 95.0%,and a design effect of *** sampling was used to build *** prevalence of GERD was determined and associated factors were studied by means of bivariate and multivariate *** A total of 1,069 subjects(47.9%women,median age 40 years)from the selected subareas were *** prevalence of GERD was 44.8%.The most frequently reported symptom was regurgitation(54.8%).One-third of subjects took medication to control symptoms and was considered‘sick’by the instrument,although>68%of them had never sought medical *** was a significant association between GERD and age(Pder(P=0.001).Conclusions In this population-based study,the prevalence of GERD was high(44.8%).GERD was associated with age and female gender.

关键词： gastroesophageal reflux disease prevalence cross-sectional studies evidence-based medicine clinical epidemiology

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The Lid-Driven Square Cavity Flow: From Stationary to Time Periodic and Chaotic

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Communications in Computational Physics 2007年第5期2卷 900-932页

作者： Salvador Garcia departamento de Ciencias Matem´aticas y F´ısicas Universidad Cat´olica de TemucoCasilla 15-D TemucoChile

Ranging from Re=100 to Re=20,000,several computational experiments are conducted,Re being the Reynolds *** primary vortex stays put,and the longterm dynamic behavior of the small vortices determines the nature of the *** low Reynolds numbers,the solution is stationary;for moderate Reynolds numbers,it is time *** high Reynolds numbers,the solution is neither stationary nor time periodic:the solution becomes *** the small vortices,the merging and the splitting,the appearance and the disappearance,and,sometime,the dragging away from one corner to another and the impeding of the merging—these mark the route to *** high Reynolds numbers,over weak fundamental frequencies appears a very low frequency dominating the spectra—this very low frequency being weaker than clear-cut fundamental frequencies seems an indication that the global attractor has been *** global attractor seems reached for Reynolds numbers up to Re=15,*** is the lid-driven square cavity flow;the motivations for studying this flow are recalled in the Introduction.

关键词： Finite differences staggered marker-and-cell(MAC)mesh incremental unknowns generalized Stokes equations incompressible Navier-Stokes equations chaos.

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Inference for a truncated positive normal distribution

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Applied Mathematics(A Journal of Chinese Universities) 2018年第2期33卷 163-176页

作者： Hector J.Gomez Neveka M.Olmos Hector Varela Heleno Bolfarine departamento de Ciencias Matematicas y Ffsicas Facultad de IngenierlaUniversidad Catolica de TemucoTemucoChile departamento de Matematicas Facultad de Ciencias BasicasUniversidad de AntofagastaAntofagastaChile departamento de Estatfstica IMEUniversidade de Sao PauloSao PauloBrazil

The main object of this paper is to study an extension of the half normal distribution defined by adding a positive truncation to it. The new model is more flexible than the half-normal distribution and contains the half normal distribution as a special case. Properties of this distribution, such as moments, hazard function and entropy are studied and parameters estimation is dealt with by using inoinents and inaxiinuin likelihood. A real data application indicates good fit performance of the new model when compared to other competitors in litera- tures.

关键词： half-normal distribution maximum likelihood truncation

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Dietary carbohydrate-to-protein ratio influences growth performance,hepatic health and dynamic of gut microbiota in atlantic salmon(Salmo salar)

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Animal Nutrition 2022年第3期10卷 261-279页

作者： Alejandro Villasante Carolina Ramírez Hector Rodríguez Patricio Dantagnan Adrian Hernandez Elías Figueroa Jaime Romero Facultad de Medicina Veterinaria y Agronomía Universidad de Las AmericasSantiagoChile Laboratorio de Biotecnología de Alimentos Unidad de AlimentosInstituto de Nutricion y Tecnología de Los Alimentos(INTA)Universidad de ChileSantiagoChile Programa de Anatomía y Biología del desarrollo Facultad de MedicinaUniversidad de ChileSantiagoChile Núcleo de Investigacion en Produccion Alimentaria Facultad de Recursos NaturalesUniversidad Catolica de TemucoTemucoChile

Atlantic salmon(Salmo salar)fed a carbohydrate-rich diet exhibit suboptimal growth performance,along with other metabolic *** is well known that gut microbes play a pivotal role in influencing metabolism of the host,and these microbes can be modified by the *** main goal of the present study was to determine the effect of feeding graded levels of digestible carbohydrates to Atlantic salmon on the distal intestine digesta microbiota at 3 sampling times(i.e.,weeks 4,8 and 12),during a 12-week trial.A low carbohydrate-to-high protein diet(LC/HP,0%wheat starch),a medium carbohydrate-tomedium protein diet(MC/MP,15%wheat starch)or a high carbohydrate-to-low protein diet(HC/LP,30%wheat starch)was fed to triplicate fish tanks(27 to 28 fish per tank).We performed an in-depth characterization of the distal intestine digesta ***,growth parameters,liver histology and the expression of genes involved in hepatic neolipogenesis in fish were *** fed a HC/LP diet showed greater hepatosomatic and viscerosomatic indexes(P=0.026 and P=0.018,respectively),lower final weight(P=0.005),weight gain(P=0.003),feed efficiency(P=0.033)and growth rate(P=0.003)compared with fish fed the LC/HP ***,feeding salmon a high digestible carbohydrate diet caused greater lipid vacuolization,steatosis index(P=0.007)and expression of fatty acid synthase(fas)and delta-6 fatty acyl desaturase(d6fad)(P=0.001 and P=0.001,respectively)in the liver compared with fish fed the LC/HP ***,the major impact of feeding a carbohydrate-rich diet to Atlantic salmon in beta diversity of distal intestine digesta microbiota was observed at week 4(HC/LP vs MC/MP and HC/LP vs LC/HP;P=0.007 and P=0.008,respectively)and week 8(HC/LP vs MC/MP;P=0.04),no differences between experimental groups were detected after 12 weeks of ***,at the end of the trial,there was a negative correlation between lactic acid bacteria(LAB)members,including Leuconostoc and Lactobacil

关键词： Microbiota Microbiome Atlantic salmon Steatosis Lactic acid bacteria Probiotics

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Gastric trichobezoar associated with perforated peptic ulcer and Candida glabrata infection

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World Journal of Clinical Cases 2014年第12期2卷 918-923页

作者： Héctor Losada Morales Cecilia Huenchullán Catalán Rodrigo Arriagada demetrio Macarena Espinoza Rivas Natalia Castagnoli Parraguez Martín Alanis Alvarez Cirugía Hepato-pancreática y Biliar Departamento de Cirugía Clínica Alemana de Temuco Temuco 4810297 Chile Cirugía Hepato-pancreática y Biliar Departamento de Cirugía y Traumatología Universidad de La Frontera Temuco 4781218 Chile departamento de Imágenes Clínica Alemana de Temuco Temuco 4810297 Chile departamento de Ginecología y Obstetricia Clínica Alemana de Temuco Temuco 4810297Chile

Bezoars are accumulations of human or plant fiber located in the gastrointestinal tract of both humans and animals. Patients remain asymptomatic for several years, and the symptoms develop as these accumulations increase in size to the point of obstruction or perforation. We report the case of a 21-year-old patient at 10 d postpartum, who presented with acute abdomen associated with sepsis. Given the urgency of the clinical picture, at no point was the presence of a giant bezoar at gastric level suspected, specifically a trichobezoar. The emergency abdominal and pelvic ultrasound revealed only unspecific signs of perforated hollow viscus. Diagnosis was therefore made intraoperatively. A complete gastric trichobezoar was found with gastric perforation and secondary peritonitis. The peritoneal fluid culture revealed Candida glabrata.

关键词： Bezoar Postpartum period Acute abdomen

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Symplectic feedback using Hamiltonian Lie algebra and its applications to an inverted pendulum

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控制理论与应用（英文版） 2013年第2期11卷 275-281页

作者： J. Lorca ESPIRO C. Munoz POBLETE departamento de Ciencias Fisicas Facultad de Ingenieria Ciencias y Administracion Universidad de La FronteraAvenida Francisco Salazar 01145 Casilla 54-D Temuco Chile departamento de Ingenieria Electrica Facultad de Ingenieria Ciencias y Administracion Universidad de La FronteraAvenida Francisco Salazar 01145 Casilla 54-D Temuco Chile

From the symplectic representation of an autonomous nonlinear dynamical system with holonomic con- straints, i.e., those that can be represented through a symplectic form derived from a Hamiltonian, we present a new proof on the realization of the symplectic feedback action, which has several theoretical advantages in demonstrating the uniqueness and existence of this type of solution. Also, we propose a technique based on the interpretation, construction and character- ization of the pull-back differential on the symplectic manifold as a member of a one-parameter Lie group. This allows one to synthesize the control law that governs a certain system to achieve a desired behavior; and the method developed from this is applied to a classical system such as the inverted pendulum.

关键词： Hamiltonian systems Symplectic structures Lie algebra Nonlinear dynamical systems Geometric con-trol

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Impacts of fire severity and cattle grazing on early plant dynamics in old-growth Araucaria-Nothofagus forests

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Forest Ecosystems 2019年第4期6卷 298-311页

作者： Paola Arroyo-Vargas Andres Fuentes-Ramírez Bart Muys Aníbal Pauchard Laboratorio de Biometría Departamento de Ciencias ForestalesUniversidad de La FronteraCasilla 54-DTemucoChile Programa de Magíster en Manejo de Recursos Naturales Facultad de Ciencias Agropecuarias y ForestalesUniversidad de La FronteraCasilla 54-DTemucoChile Butamallin Research Center for Global Change Universidad de La FronteraTemucoChile Instituto de Ecología y Biodiversidad(IEB) SantiagoChile department of Earth and Environmental Sciences University of LeuvenCelestijnenlaan 200EBox 24113001 LeuvenBelgium Laboratorio de Invasiones Biológicas(LIB) Facultad de Ciencias ForestalesUniversidad de ConcepciónCasilla 160-CConcepciónChile.

Background: Fire has historically shaped the dynamics of Araucaria araucana-Nothofagus pumilio forests in the Andean region of South America. Nevertheless, human disturbances and stronger drought events have resulted in increased occurrence and severity of wildfires. Regardless of their conservation relevance, the initial response to fire of Araucaria-Nothofagus forests has not been well documented. Through this research we tested the hypothesis that plant composition of Araucaria-Nothofagus forest after fire will initially differ in its recovery depending on fire severity, but over time, plant similarity will increase among areas with different levels of fire severity. The study was carried out in old-growth Araucaria-Nothofagus forests in south-central Chile(38°S) that were burned in 2015. We studied vegetation response to three levels of fire severity(low(LS), moderate(MS) and high(HS) severity), also including an adjacent unburned forest(UN), which were assessed one, two and three years after fire. We also evaluated the impact of cattle on plant recovery after fire. We measured species richness, abundance, plant diversity and origin of all vascular plant ***: Species richness and plant abundance responded differently to fire severity. Time-since-fire had a significant effect on plant richness and abundance. Plant composition within LS areas was similar to UN areas, but MS and HS areas were significantly less diverse compared to UN and LS. In absence of other major disturbances, similarity in plant composition tended to increase over time across the different levels of fire severity, becoming more similar to UN. We also found a synergetic effect of cattle and fire on species richness. This interaction promotes the establishment of nonnative species and limits the recovery of native species following ***: Fire severity had a significant impact on the plant community of old-growth Araucaria-Nothofagus forests,especially in areas of high fir

关键词： Fire severity gradient Wildfire Post-fire plant recovery Cattle exclusion Synergistic effects of disturbances Araucaria araucana Nothofagus pumilio

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Phase transitions in four-dimensional AdS black holes with a nonlinear electrodynamics source

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Communications in Theoretical Physics 2021年第12期73卷 119-128页

作者： Ramon Becar P A Gonzalez Joel Saavedra Yerko Vasquez Bin Wang departamento de Ciencias Matematicas y Fisicas Universidad Catolica de TemucoMontt 56Casilla 15-DTemucoChile Facultad de Ingenieria y Ciencias Universidad Diego PortalesAvenida Ejercito Libertador 441Casilla 298-VSantiagoChile Instituto de Ffsica Pontificia Universidad Catolica de ValparaisoCasilla 4950ValparaisoChile departamento de Ffsica Facultad de CienciasUniversidad de La SerenaAvenida Cistemas 1200La SerenaChile Center for Gravitation and Cosmology College of Physical Science and TechnologyYangzhou UniversityYangzhou 225009China

In this work we consider black hole solutions to Einstein’s theory coupled to a nonlinear powerlaw electromagnetic field with a fixed exponent *** study the extended phase space thermodynamics in canonical and grand canonical ensembles,where the varying cosmological constant plays the role of an effective thermodynamic *** examine thermodynamical phase transitions in such black holes and find that both first-and second-order phase transitions can occur in the canonical ensemble while,for the grand canonical ensemble,Hawking-Page and second-order phase transitions are allowed.

关键词： black hole thermodynamics nonlinear Maxwell

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Analysing changes in spatial point patterns:A proposal using data from a forest thinning experiment

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Forest Ecosystems 2022年第6期9卷 878-887页

作者： Christian Salas-Eljatib Joaquín Riquelme-Alarcon Pablo J.Donoso Diego Ponce Daniel P.Soto Centro de Modelacion y Monitoreo de Ecosistemas Escuela de Ingeniería ForestalUniversidad MayorSantiagoChile Vicerrectoría de Investigacion y Postgrado Universidad de La FronteraTemucoChile departamento de Silvicultura y Conservacion de la Naturaleza Universidad de ChileSantiagoChile Instituto de Bosques y Sociedad Universidad Austral de ChileValdiviaChile Corporacion Nacional Forestal ValdiviaChile departamento de Ciencias Naturales y Tecnología Universidad de AysenCoyhaiqueChile

Spatial patterns reveal critical features at the individual and community ***,how to evaluate changes in spatial characteristics remains largely *** assess spatial changes in spatial point patterns by augmenting current statistical functions and *** fitted functions to describe unmarked and marked(tree size)spatial patterns using data from a large-scale silvicultural experiment in southern ***,we compute the mingling index to represent spatial tree *** proffer the pair correlation function difference before and after treatment to detect changes in the unmarked-point pattern of trees and the semivariogram-ratio to evaluate changes in the marked-point *** research provides a quantitative assessment of a critical aspect of forest heterogeneity:changes in spatial unmarked and marked-point *** proposed approach can be a powerful tool for quantifying the impacts of disturbances and silvicultural treatments on spatial patterns in forest ecosystems.

关键词： Spatial diversity Marked-point process Spatial heterogeneity Conspecific Variable-density thinning Nothofagus

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