检索结果-南通市图书馆

Mechanisms of vascular injury in neurotrauma: A critical review of the literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Meta-Analysis 2024年第3期12卷 6-16页

作者： Jonathan Willman Annu Lisa Kurian Brandon Lucke-Wold College of Medicine University of FloridaGainesvilleFL 32610United States College of Medicine Florida State UniversityTallahasseeFL 32304United States department of Neurosurgery University of FloridaGainesvilleFL 32611United States

One in every two individuals will experience a traumatic brain injury in their lifetime with significant impacts on the global economy and healthcare system each *** injury is a key aspect of neurotrauma to both the brain and the spinal cord and an important avenue of current and future research seeking innovative *** this paper,we discuss primary and secondary neurotrauma,mechanisms of injury,the glymphatic system,repair and *** of these topics are directly connected to the vasculature of the central ner-vous system,affecting severity of injury and ***,neurova-scular injury in trauma represents a promising target for future therapeutics and innovation.

关键词： Neurotrauma Neurovascular injury Primary neurotrauma Secondary neurotrauma traumatic brain injury traumatic spinal cord injury Glymphatic system Vascular Injury

Bioinspired Hemostatic Strategy via Pulse Ejections for Severe Bleeding Wounds

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2024年第1期2023卷 281-299页

作者： Bitao Lu Enling Hu Weiwei Ding Wenyi Wang Ruiqi Xie Kun Yu Fei Lu Guangqian Lan Fangyin Dai State Key Laboratory of Silkworm Genome Biology College of SericultureTextile and Biomass SciencesSouthwest UniversityChongqing 400715China Chongqing Engineering Research Center of Biomaterial Fiber and Modern Textile Chongqing 400715China Division of trauma and Surgical Intensive Care Unit Research Institute of General SurgeryJinling HospitalMedical School of Nanjing UniversityNanjing210002 Jiangsu ProvinceChina department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHong KongChina

Efficient hemostasis during emergency trauma with massive bleeding remains a critical challenge in prehospital ***,multiple hemostatic strategies are critical for treating large bleeding *** this study,inspired by bombardier beetles to eject toxic spray for defense,a shape-memory aerogel with an aligned microchannel structure was proposed,employing thrombin-carrying microparticles loaded as a built-in engine to generate pulse ejections for enhanced drug *** aerogels,after contact with blood,can rapidly expand inside the wound,offering robust physical barrier blocking,sealing the bleeding wound,and generating a spontaneous local chemical reaction causing an explosivelike generation of CO_(2) microbubbles,which provide propulsion thrust to accelerate burst ejection from arrays of microchannels for deeper and faster drug *** ejection behavior,drug release kinetics,and permeation capacity were evaluated using a theoretical model and experimentally *** novel aerogel showed remarkable hemostatic performance in severely bleeding wounds in a swine model and demonstrated good degradability and biocompatibility,displaying great potential for clinical application in humans.

关键词： wound sealing offering

Isolation and characterization of mesenchymal stem cells in orthopaedics and the emergence of compact bone mesenchymal stem cells as a promising surgical adjunct

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2020年第11期12卷 1341-1353页

作者： Albert Anastasio Marina Gergues Michael S Lebhar Pranela Rameshwar Joseph Fernandez-Moure department of Orthopedic Surgery Duke University Health SystemDurhamNC 27710United States department of Medicine Hematology/OncologyRutgers UniversityNew Jersey Medical SchoolNewarkNJ 07103United States School of Medicine Duke University School of MedicineDurhamNC 27710United States department of Medicine-Hematology/Oncology Rutgers School of Biomedical Health ScienceNewarkNJ 07103United States department of Surgery Division of TraumaAcuteand Critical Care SurgeryDuke University School of MedicineDurhamNC 27710United States

The potential clinical and economic impact of mesenchymal stem cell(MSC)therapy is *** act through multiple pathways:(1)as“trophic”cells,secreting various factors that are immunomodulatory,anti-inflammatory,antiapoptotic,proangiogenic,proliferative,and chemoattractive;(2)in conjunction with cells native to the tissue they reside in to enhance differentiation of surrounding cells to facilitate tissue *** have developed methods for the extraction and expansion of MSCs from animal and human *** many sources of MSCs exist,including adipose tissue and iliac crest bone graft,compact bone(CB)MSCs have shown great potential for use in orthopaedic *** MSCs exert powerful immunomodulatory effects in addition to demonstrating excellent regenerative capacity for use in filling boney *** MSCs have been shown to have enhanced response to hypoxic conditions when compared with other forms of *** work is needed to continue to characterize the potential applications for CB MSCs in orthopaedic trauma.

关键词： Compact bone Mesenchymal stem cells Stem cells trauma Orthopedic Regeneration

Novel predictors of permanent pacemaker implantation following transcatheter aortic valve replacement

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2023年第11期15卷 582-598页

作者： Somto Nwaedozie Haibin Zhang Javad Najjar Mojarrab Param Sharma Paul Yeung Peter Umukoro Deepa Soodi Rachel Gabor Kelley Anderson Romel Garcia-Montilla department of Cardiovascular Disease Marshfield ClinicMarshfieldWI 54449United States Hospitalist Medicine Marshfield ClinicMarshfieldWI 54449United States department of Nephrology Henry Ford Health SystemDetroitMI 48202United States department of Hospital Medicine Marshfield ClinicMarshfieldWI 54449United States department of Nephrology Hendricks Regional HealthDanvilleIN 46122United States Clinical Research Center Marshfield ClinicMarshfieldWI 54449United States department of trauma Surgery and Surgical Critical Care Marshfield ClinicMarshfieldWI 54449United States

BACKGROUND Conduction and rhythm abnormalities requiring permanent pacemakers(PPM)are short-term complications following transcatheter aortic valve replacement(TAVR),and their clinical outcomes remain *** novel predictors of post-TAVR PPM,like QRS duration,QTc prolongation,and supraventricular arrhythmias,have been poorly *** To evaluate the effects of baseline nonspecific interventricular conduction delay and supraventricular arrhythmia on post-TAVR PPM requirement and determine the impact of PPM implantation on clinical *** RESULTS Out of the 357 patients that met inclusion criteria,the mean age was 80 years,188(52.7%)were male,and 57(16%)had a PPM *** demographics,valve type,and cardiovascular risk factors were similar except for type II diabetes mellitus(DM),which was more prevalent in the PPM cohort(59.6%vs 40.7%;P=0.009).The PPM cohort had a significantly higher rate of pre-procedure right bundle branch block,prolonged QRS>120 ms,prolonged QTc>470 ms,and supraventricular *** was a consistently significant increase in the odds ratio(OR)of PPM implantation for every 20 ms increase in the QRS duration above 100 ms:QRS 101-120[OR:2.44;confidence intervals(CI):1.14-5.25;P=0.022],QRS 121-140(OR:3.25;CI:1.32-7.98;P=0.010),QRS 141-160(OR:6.98;CI:3.10-15.61;P120(aOR:2.18;CI:1.02-4.66;P=0.045)and marginally significant for supraventricular arrhythmias(aOR:1.82;CI:0.97-3.42;P=0.062).The PPM cohort had a higher adjusted OR of heart failure(HF)hospitalization(aOR:2.2;CI:1.1-4.3;P=0.022)and nonfatal myocardial infarction(MI)(aOR:3.9;CI:1.1-14;P=0.031)without any difference in mortality(aOR:1.1;CI:0.5-2.7;P=0.796)at one *** Pre-TAVR type II DM and QRS duration>120,regardless of the presence of bundle branch blocks,are predictors of post-TAVR *** 1-year post-

关键词： Transcatheter aortic valve replacement Balloon-expandable valve Self-expandable valve Myocardial infarction Left bundle-branch block Nonspecific inter-ventricular defect Coronary artery bypass graft Coronary artery disease

Description of trauma among French service members in the department of defense trauma Registry: Understanding the nature of trauma and the care provided

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Military Medical Research 2019年第4期6卷 275-283页

作者： Marc A.Schweizer Jud C.Janak Zsolt T.Stockinger Tristan Monchal united states department of defense joint trauma system Joint Base San Antonio Fort Sam HoustonHoustonTX 78234USA Naval Medical Readiness Training Command Jacksonville JacksonvilleFL 32212USA Sainte Anne Military Hospital 600-83800 Toulon Cedex 9BPFrance

Background:Since 2001,the French Armed Forces have sustained many casualties during the Global War on Terror;however,even today,there is no French Military trauma *** French service members(SMs)were treated in US Military Medical Treatment Facilities(MTFs)and were recorded in the US department of defense trauma Registry(Do DTR).Our objective was to conduct a descriptive analysis of the injuries sustained by French SMs reported in the Do DTR and subsequent care provided to them to assist in understanding the importance of building a French Military trauma ***:Using Do DTR data collected from 2001 to 2017,a retrospective descriptive analysis was *** identified 59 French SMs treated in US *** characteristics of the SMs’demographics,injuries,care provided to them,and discharge outcomes were ***:Among the 59 French SMs identified,46(78%)sustained battle injuries(BIs)and 13(22%)sustained nonbattle injuries(NBIs).There were 47(80%)SMs injured in Afghanistan(Opération Pamir),while 12(20%)were injured in Opération Chammal in Iraq and *** accounted for 52.5%of injuries,while 25.4%were due to gunshot wounds;all were *** majority of reported injuries were penetrating(59.3%),most of which were BIs(71.7%).The mean Injury Severity Score for BIs was 12(SD=8.9)compared to 6(SD=1.7)for *** half of SMs(n=30;51%)were injured in Afghanistan between the years 2008–*** a total of 246 injuries sustained by 59 patients,extremities were the body part most prone to BIs followed by the head and *** SMs died after admission(6.8%).Conclusions:The Do DTR provides extensive data on trauma injuries that can be used to inform injury prevention and clinical *** majority of injuries sustained by French SMs were BIs,caused by explosives,and predominantly occurring to the extremities;these findings are similar to those of other studies conducted in combat *** is a need to establish a French Military tr

关键词： French service members US military treatment facility trauma registry

Ultrasound-assisted musculoskeletal procedures:A practical overview of current literature

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2011年第7期2卷 57-66页

作者： Nelson A Royall Emily Farrin David P Bahner Stanislaw PA Stawicki department of Emergency Medicine The Ohio State University Medical CenterColumbusOH 43210United States department of Orthopaedics The Ohio State University Medical CenterColumbusOH 43210United States department of Surgery Division of Critical CareTrauma and BurnThe Ohio State Unviersity Medical CenterColumbusOH 43210United States

Traditionally performed by a small group of highly trained specialists,bedside sonographic procedures involving the musculoskeletal system are often delayed despite the critical need for timely diagnosis and *** to this limitation,a need evolved for more portability and accessibility to allow performance of emergent musculoskeletal procedures by adequately trained non-radiology *** emergence of ultrasound-assisted bedside techniques and increased availability of portable sonography provided such an opportunity in select clinical *** review summarizes the current literature describing common ultrasound-based musculoskeletal ***-depth discussion of each ultrasound procedure including pertinent technical details,indications and contraindications is *** the limited amount of prospective,randomized data in this area,a substantial body of observational and retrospective evidence suggests potential benefits from the use of musculoskeletal bedside sonography.

关键词： Musculoskeletal ultrasound-guided procedures Arthrocentesis Tendon injection Articular injection Fluid collection Abscess drainage Foreign body removal

Evaluation of biogenic markers-based phenotyping for resistance to Aphanomyces root rot in field pea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Information Processing in Agriculture 2022年第1期9卷 1-10页

作者： Afef Marzougui Abirami Rajendran D.Scott Mattinson Yu Ma Rebecca J.McGee Manuel Garcia-Perez Stephen P.Ficklin Sindhuja Sankaran department of Biological systems Engineering Washington State UniversityPullmanWAUnited States department of Horticulture Washington State UniversityPullmanWAUnited States united states department of Agriculture-Agricultural Research Service Grain Legume Genetics and Physiology Research UnitWashington State UniversityPullmanWAUnited States

Biogenic volatile organic compounds(VOCs)emitted by plants can reveal information about plant adaptation,defense processes,and biological ***,such VOC data may be utilized to capture phenotypic plant responses to the *** this study,the main objective was to evaluate the potential of biogenic compounds,including VOCs,to phenotype two pea cultivars,Ariel(susceptible)and Hampton(high levels of partial resistance)for resistance to Aphanomyces root rot *** were monitored non-destructively for VOC emission at three-time points(15,20,and 30 days after inoculation,DAI)using dynamic headspace sampling with gas chromatography-flame ionization detec-tion(GC-FID)system,as well as destructively at the end of the experiments,using solvent extraction and pyrolysis of both shoot and root tissues.A non-inoculated control(mock-inoculated with distilled water)was utilized to compare the plant responses within a *** common chemical peaks between control and inoculated samples of both culti-vars(RT_(cm))were analyzed after normalizing the relative peak intensity of inoculated samples with those of control samples,prior to a comparison between *** addi-tion,unique chemical peaks(RT_(uq))present in inoculated samples,but not in control sam-ples were also identified and their relative peak intensities were *** the released green leaf volatiles(RT_(cm)),the normalized relative peak intensity of hexanal emis-sion,at 20 DAI,was higher in Ariel than that of *** addition,several putative chemical peaks(both RT_(cm) and RT_(uq)),previously known as indicators for disease response,exhibited some differences in their emission rates between pea cultivars in at least one of the time *** destructive sampling revealed that shoot samples produced more putative unique biomarkers(RT_(uq))than the root *** on the differences in puta-tive chemical peaks between cultivars,this initial study supports the concept of utilizat

关键词： Plant breeding Pulse crop Volatile organic compounds Plant phenotyping Biotic stress

Quantum parameter estimation in a spin-boson dephasing quantum system by periodical projective measurements

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2018年第4期27卷 242-249页

作者： Le Yang Hong-Yi Dai Ming Zhang College of Artificial Intelligence National University of Defense Technology Changsha 410073 China department of Physics National University of Defense Technology Changsha 410073 China Interdisciplinary Center for Quantum Information National University of Defense Technology Changsha 410073 China

In this paper,we explore how to estimate the phase damping parameter γ and the tunneling amplitude parameter ？from a spin-boson dephasing quantum model by periodical projective *** preparation of initial states is accomplished by performing the period measurements in our *** parameter γ can be always estimated when projective measurement bases are chosen as θ = π/2 and φ = *** on the estimated value of γ and the interval information of ？,we can select another measurement bases（θ = π/4 and φ = π/2） to obtain the estimated value of ？.A coherent control is indispensable to estimate ？ if γ is in the interval of ？;whereas the control is not necessary if γ is out of the known interval of ？.We establish the relation between the optimal period time and the parameter γ or ？ in terms of Fisher *** the optimal measurement period cannot be selected beforehand,the aforementioned relation can be utilized to adjust the measurement period to approach the optimal one.

关键词： parameter estimation periodical projective measurement spin-boson model dephasing quantum system

A New Approach to the Quantum Adiabatic Condition

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2012年第10期29卷 5-8页

作者： GUO Chu DUAN Qian-Heng CHEN Ping-Xing department of Physics National University of Defense TechnologyChangsha 410073 State Key Laboratory of High Performance Computing National University of Defense TechnologyChangsha 410073

The quantum adiabatic theorem is the basis of adiabatic quantum ***,the exact necessary and sufficient conditions for adiabatic evolution are still under *** discuss the adiabatic condition of a system undergoing a special evolution route,and obtain an explicit formula that is necessary and sufficient for the adiabatic evolution in this *** on this formula,we find that the traditional adiabatic condition is neither sufficient nor ***,we show that no adiabatic process can occur even the evolution speed goes to 0 in some examples,which is surprising since the adiabatic theorem states that if the evolution of a system is slow enough,the adiabatic process could occur.

关键词： computation adiabatic quantum