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Prevalence of hypercoagulable states in stented thrombotic iliac vein compression syndrome with comparison of re-intervention and anticoagulation regimens

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World Journal of radiology 2021年第12期13卷 371-379页

作者： Peyton Cramer Cheryl Mensah Maria DeSancho Anuj Malhotra Ronald Winokur Andrew Kesselman Department of radiology Division of Interventional RadiologyNew York Presbyterian Hospital/Weill Cornell MedicineNew YorkNY 10065United States Department of Medicine Division of Hematology-OncologyNew York Presbyterian Hospital/Weill Cornell MedicineNew YorkNY 10065United States Department of radiology Division of Interventional RadiologyThomas Jefferson University HospitalPhiladelphiaPennsylvania 19107United States

BACKGROUND Endovascular therapy is playing an increasing role in the treatment of iliofemoral venous *** stent patency is multifactorial,and current management is based on best clinical practices,varying by *** To evaluate how thrombophilia influences management and outcomes of patients who undergo venous stenting for thrombotic iliac vein compression *** A retrospective observational analysis was performed on 65 patients with thrombotic iliac vein compression syndrome that underwent common iliac vein(CIV)stenting between December 2013 and December 2019 at a large academic *** criteria included CIV stenting and iliac vein *** lesions and iliocaval thrombosis and/or occlusions were excluded.A total of 65 patients were selected for final *** information,procedural data points,and post-procedural management and outcomes were *** analyses included Fisher's exact and Chi-square tests to compare discrete variables and the Wilcoxon rank-sum test to compare continuous variables between thrombophilia positive and negative *** 65 patients underwent successful balloon angioplasty and CIV *** these patients,33(50.8%)underwent thrombophilia testing,with 16(48.5%)testing *** patency on ultrasound did not significantly differ between thrombophilia positive and negative patients at 1 mo(92.3%vs 81.3%,P=0.6),6 mo(83.3%vs 80%,P>0.9),or 12 mo(77.8%vs 76.9%,P=0.8).Immediately after stent placement,thrombophilia patients were more likely to be placed on dual therapy(aspirin and anticoagulation)or triple therapy(aspirin,clopidogrel,and anticoagulation)(50%vs 41.2%,P>0.9),and remain on dual therapy at 6 mo(25%vs 12.5%,P=0.5)and 12 mo(25%vs 6.7%,P=0.6).There was no significant difference in re-intervention rates(25%vs 35.3%,P=0.7)or number of reinterventions(average 2.3 vs 1.3 per patient,P=0.4)between thrombophilia positive and negative ***

关键词： Thrombophilia Iliac vein compression syndrome Iliac vein stent May Thurner Anticoagulation Endovascular

Structural changes in the gray matter of unmedicated patients with obsessive-compulsive disorder: a voxel-based morphometric study

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Neuroscience Bulletin 2013年第5期29卷 642-648页

作者： Ling Tan Qing Fan Chao You Jijun Wang Zhao Dong Xuemei Wang Kemin Chen Zeping Xiao Kaida Jiang Department of radiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Department of Clinical Psychology Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine School of Pharmacy Shanghai University of Traditional Chinese Medicine

The aim of the current study was to use whole brain voxel-based morphometry（VBM）to assess the gray matter（GM）changes in unmedicated patients with obsessive-compulsive disorder（OCD）compared with normal *** compared the GM volumes in28 patients with 22 matched healthy controls using a1.5T ***-dimensional T1-weighted magnetic resonance images were obtained from all *** was performed to detect GM volume differences between the two *** detected increased regional GM volumes in the bilateral middle temporal gyri,bilateral middle occipital gyri,bilateral globus pallidus,right inferior parietal gyrus,left superior parietal gyrus,right parahippocampus,right supramarginal gyrus,right medial superior frontal gyrus,and left inferior frontal opercular cortex in the OCD patients relative to controls（P〈0.001,uncorrected,cluster size〉100 voxels）.No decreased GM volume was found in the OCD group compared with normal *** findings suggest that structural changes in the GM are not limited to fronto-striato-thalamic circuits in the pathogenesis of ***-parietal cortex may also play an important role.

关键词： obsessive-compulsive disorder magnetic resonance imaging voxel-based morphometry gray matter

Surgical outcomes of mini-open Wiltse approach and conventional open approach in patients with single-segment thoracolumbar fractures without neurologic injury

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The Journal of Biomedical Research 2015年第1期29卷 76-82页

作者： Haijun Li Lei Yang Hao Xie Lipeng Yu Haifeng Wei Xiaojian Cao Department of Orthopaedics the First Affiliated Hospital of Nanjing Medical University Department of Orthopaedics the Second Affiliated Hospital of Nanjing Medical University Department of radiology Taizhou People's Hospital affiliated to Nantong University

This study aimed to introduce a novel mini-open pedicle screw fixation technique via Wiltse approach, and com- pared it with the traditional posterior open method. A total of 72 cases of single-segment thoracolumbar fractures without neurologic injury underwent pedicle screw fixation via two different approaches. Among them, 37 patients were treated using posterior open surgery, and 35 patients received mini-open operation via Wiltse approach. Crew placement accuracy rate, operative time, blood loss, postoperative drainage, postoperative hospitalization time, radiation exposure time, postoperative improvement in R value, Cobb＇s angle and visual analog scale （VAS） scores of the two methods were compared. There were no significant differences in the accuracy rate of pedicle screw placement, radiation exposure and postoperative R value and Cobb＇s angle improvement between the two groups. However, the mini-open method had obvious advantages over the conventional open method in operative time, blood loss, postoperative drainage, postoperative hospitalization time, and postoperative improvement in VAS. The mini-open pedicle screw technique could be applied in treatment of single-segment thoracolumbar fracture without neurologic injury and had advantages of less tissue trauma, short operative and rehabilitative time on the premise of guaranteed accuracy rate and no increased radiation exposure.

关键词： thoracolumbar fracture pedicle screw Mini-open Wiltse approach minimally invasive

Recent advances of deep learning in psychiatric disorders

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Precision Clinical Medicine 2020年第3期3卷 202-213页

作者： Lu Chen Chunchao Xia Huaiqiang Sun West China Medical Publishers West China Hospital of Sichuan UniversityChengdu 610041China Department of radiology West China Hospital of Sichuan UniversityChengdu 610041China

Deep learning(DL)is a recently proposed subset of machine learning methods that has gained extensive attention in the academic world,breaking benchmark records in areas such as visual recognition and natural language *** fromconventional machine learning algorithm,DL is able to learn useful representations and features directly from raw data through hierarchical nonlinear *** of its ability to detect abstract and complex patterns,DL has been used in neuroimaging studies of psychiatric disorders,which are characterized by subtle and diffuse ***,we provide a brief review of recent advances and associated challenges in neuroimaging studies of DL applied to psychiatric *** results of these studies indicate that DL could be a powerful tool in assisting the diagnosis of psychiatric *** conclude our review by clarifying the main promises and challenges of DL application in psychiatric disorders,and possible directions for future research.

关键词： deep learning machine learning neuroimaging autoencoders convolutional neural networks deep belief networks mental disorders psychiatric disorders

Glucose uptake and distribution across the human skeleton using state-of-the-art total-body PET/CT

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骨研究:英文版 2023年第3期11卷 586-594页

作者： Weizhao Lu Yanhua Duan Kun Li Jianfeng Qiu Zhaoping Cheng Department of radiology Shandong First Medical University&Shandong Academy of Medical SciencesTaian 271016China Department of PET-CT the First Affiliated Hospital of Shandong First Medical UniversityShandong Provincial Qianfoshan Hospital Affiliated with Shandong UniversityJinan 250014China

A growing number of studies have demonstrated that the skeleton is an endocrine organ that is involved in glucose metabolism and plays a significant role in human glucose ***,there is still a limited understanding of the in vivo glucose uptake and distribution across the human *** address this issue,we aimed to elucidate the detailed profile of glucose uptake across the skeleton using a total-body positron emission tomography(PET)scanner.A total of 41 healthy participants were *** of them received a 1-hour dynamic total-body^(18)F-fluorodeoxyglucose(^(18)F-FDG)PET scan,and all of them received a10-minute static total-body^(18)F-FDG PET *** net influx rate(K_i)and standardized uptake value normalized by lean body mass(SUL)were calculated as indicators of glucose uptake from the dynamic and static PET data,*** results showed that the vertebrae,hip bone and skull had relatively high Kiand SUL values compared with metabolic organs such as the *** the K_(i) and SUL were higher in the epiphyseal,metaphyseal and cortical regions of long ***,trends associated with age and overweight with glucose uptake(SUL_(max)and SUL_(mean))in bones were ***,these results indicate that the skeleton is a site with significant glucose uptake,and skeletal glucose uptake can be affected by age and dysregulated metabolism.

关键词： metabolism skeleton organs

动态增强MR成像对新辅助化疗原发性乳腺癌生存期的预测

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国际医学放射学杂志 2011年第5期 472-473页

作者： A.Makris M.J.Beresford N.J.Taylor M.L.W.Ah-See J.J.Stirling 刘芳 academic Oncology unit Mount Vernon Cancer CentreRickmansworth RdNorthwoodMiddlesexHA6 2RNEngland

目的探讨原发性乳腺癌2个周期新辅助化疗(NAC)后行动态增强MR成像并测量其早期血管参数变化以预测无病生存期和总生存期的可行性。材料与方法本研

关键词：乳腺癌总生存期无病生存乳腺肿瘤动态增强新辅助化疗原发性 MR

高空间分辨力双能量X线吸收骨密度仪的自由兴趣区数据分析

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国际医学放射学杂志 2015年第2期 181-182页

作者： R.M.Morris L.Yang M.A.Martín-Fernández J.M.Pozo A.F.Frangi J.M.Wilkinson 赵芳 academic unit of Bone Metabolism University of Sheffield Northern General Hospital Beech Hill Road Sheffield S102RXEngland

摘要目的概述双能量骨密度吸收(DXA)自由兴趣区分析技术的进展,定量分析其精确性,评估其在全髋关节置换术12个月后对纵向股骨假体骨密度(BMD)定量分析方面

关键词：兴趣区 DXA 空间分辨力空间分辨率 BMD 双能量

采用MRI形态学特征和表观扩散系数预测WHO分级的Ⅱ、Ⅲ级胶质瘤分子状态

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国际医学放射学杂志 2020年第5期 610-610页

作者： J.Maynard S.Okuchi S.Wastling A.A.Busaidi O.Almossawi W.Mbatha 冯逢 Neuroradiological academic unit Department of BrainRepair and Rehabilitation UCL Institute of Neurology

摘要目前缺乏一种现成的用于胶质瘤基因分型的MRI生物标志物。目的评估临床可获得的MRI参数是否可以预测胶质瘤病人的异柠檬酸脱氢酶(IDH)基因状态。材料

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三核混合MRI肺结构和功能的同时成像

国际医学放射学杂志 2013年第3期 280-280页

作者： J.M.Wild H.Marshall X.Xu G.Norquay S.R.Parnell M.Clemence 张业坡 academic unit of radiology University of SheffieldC FloorRoyal Hallamshire Hospital

目的重新设计一个标准的临床MRI体系,在相同的屏气条件下,能同时采集已知的解剖学质子(1H)所生成的MR肺结构图以及由超极化气体(3He和129Xe)所生成的肺部影像。材料与方法本研究获得国家研究伦理委员会批准,并由志愿者签署知情同意书。... 详细信息

目的重新设计一个标准的临床MRI体系,在相同的屏气条件下,能同时采集已知的解剖学质子(1H)所生成的MR肺结构图以及由超极化气体(3He和129Xe)所生成的肺部影像。材料与方法本研究获得国家研究伦理委员会批准,并由志愿者签署知情同意书。在同样呼吸下,使用互不偶联的嵌套射频线圈互不干扰地各自发射和采集氢、氦及氙原子核所产生的MR影像。同时开发了适用于原子核间快速转换的MR脉冲序列。该系统获得了一个健康志愿者吸入3He和129Xe混合气体的三核肺部MR影像。结果同样呼吸下所有三核的时空配准影像均具有高信噪比和高空间分辨率。结论多核技术能提供解剖结构和功能相互弥补的标准肺部MR影像。

关键词：肺结构 MRI 原子核功能