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Is economic fitness helpful in achieving environmental sustainability in BRICS economies?A risk exposure perspective

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Chinese Journal of Population,Resources and Environment 2024年第2期22卷 109-117页

作者： Jabbar Ul-Haq Hubert Visas Muhlis Can Qazi Muhammad Adnan Hye Noreen Aslama Department of Economics University of SargodhaSargodha 40100Pakistan School of International Trade&Economics University of International Business and EconomicsBeijing 100029China Middle East University Amman 11831Jordan Vishi Higher Institute DoualaCameroon BETA Akademi Social Sciences Research Lab(SSR Lab)Istanbul 34000Turkey academic Research and Development Wing DubaiUnited Arab Emirates

A country’s ability to create complex goods and diversify its lines of products is essential for addressing all types of *** a country’s vulnerability to extreme climatic events,such as droughts,superstorms,and other natural disasters,and its capacity for successful adaption,is an essential global need that has been *** study examines the role of economic fitness(EF)in addressing climate change risk ex‐posure in BRICS countries in the context of the environmental Kuznets curve using panel data from 1995 to *** threshold methodology is employed to ascertain the nonlinear relationship between EF and climate change risk exposure(i.e.,Notre Dame Global Adaptation Initiative Country Index(ND-GAIN)).In addition,empirical associations were estimated using panel-corrected standard errors,Driscoll-Kraay standard errors,and feasible generalized least squares estimation *** findings demonstrated an inverted N shaped link between EF and ***,even after controlling for significant ND-GAIN influencing variables such as gross domestic product per capita,financial development,and urbanization,our robustness checks revealed significant and consistent findings.

关键词： Economic fitness Climate change BRICS countries Environmental Kuznets Curve Notre Dame Index

Screening for early-onset neonatal sepsis on the Kaiser Permanente sepsis risk calculator could reduce neonatal antibiotic usage by two-thirds

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Pediatric Investigation 2022年第3期6卷 171-178页

作者： Michelle Fernandes Lucinda Winckworth Lyrille Lee Madiha Akram Simon Struthers The Department of Neonatal Medicine and the Neonatal Intensive care unit Princess Anne HospitalUniversity Hospitals Southampton NHS Foundation TrustSouthamptonUK The MRC Lifecourse Epidemiology Centre and Human Development and Health academic unit Faculty of MedicineUniversity of SouthamptonSouthamptonUK Nuffield Department of Women’s and Reproductive Health John Radcliffe HospitalUniversity of OxfordOxfordUK Department of Pediatrics Royal Hampshire County HospitalWinchesterUK

Importance:Effective screening strategies for early-onset neonatal sepsis(EONS)have the potential to reduce high volume parenteral antibiotics(PAb)usage in ***:To compare management decisions for EONS,between CG149 National Institute for Health and care Excellence(NICE)guidelines and those projected through the virtual application of the Kaiser Permanente sepsis risk calculator(SRC)in a level 2 neonatal unit at a district general hospital(DGH).Methods:Hospital records were reviewed for maternal and neonatal risk factors for EONS,neonatal clinical examination findings,and microbial culture results for all neonates born at≥34 weeks’gestation between February and July 2019,who were(1)managed according to CG149-NICE guidelines or(2)received PAb within 72 h following birth at a DGH in Winchester,*** projections were obtained using its virtual risk ***:Sixty infants received PAb within the first 72 h of birth during the study *** these,19(31.7%)met SRC criteria for antibiotics;20(33.3%)met the criteria for enhanced observations and none had culture-proven *** on SRC projections,neonates with’’≥1 NICE clinical indicator and≥1 risk factor’were most likely to have a sepsis risk score(SRS)>*** below 37 weeks’gestation(risk ratio[RR]=2.31,95%confidence interval[CI]:1.02–5.22)and prolonged rupture of membranes(RR=3.14,95%CI:1.16–8.48)increased the risk of an SRS>***:Screening for EONS on the SRC could potentially reduce PAb usage by 68%in term and near-term neonates in level 2 neonatal units.

关键词： Early onset neonatal sepsis Kaiser Permanente sepsis risk calculator NICE guidelines Parenteral antibiotics

Liquid Phase Exfoliation of 2D Materials and Its ElectrochemicalApplications in the Data-Driven Future

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Precision Chemistry 2024年第7期2卷 300-329页

作者： Panwad Chavalekvirat Wisit Hirunpinyopas Krittapong Deshsorn Kulpavee Jitapunkul Pawin Iamprasertkun School of Bio-Chemical Engineering and Technology Sirindhorn International Institute of TechnologyThammasat UniversityPathum Thani 12120ThailandResearch Unit in Sustainable Electrochemical IntelligentThammasat UniversityPathum Thani 12120Thailand Department of Chemistry Faculty of ScienceKasetsart UniversityBangkok 10900Thailand Department of Chemical Engineering Faculty of EngineeringKasetsart UniversityBangkok 10900Thailand

The electrochemical properties of 2D materials,particularly transition metal dichalcogenides(TMDs),hinge ontheir structural and chemical *** be practicallyviable,achieving large-scale,high-yield production is crucial,ensuring both quality and electrochemical suitability forapplications in energy storage,electrocatalysis,and potentialbasedionic sieving membranes.A prerequisite for success is a deepunderstanding of the synthesis process,forming a critical linkbetween materials synthesis and electrochemical *** extensively examines the liquid-phase exfoliation technique,providing insights into potential advancements and strategies tooptimize the TMDs nanosheet yield while preserving theirelectrochemical *** primary goal is to compiletechniques for enhancing TMDs nanosheet yield through direct liquid-phase exfoliation,considering parameters like solvents,surfactants,centrifugation,and sonication *** addressing the exfoliation yield,the review emphasizes the potentialimpact of these parameters on the structural and chemical properties of TMD nanosheets,highlighting their pivotal role inelectrochemical *** evolving research methodologies,the review explores integrating machine learning anddata science as tools for understanding relationships and key *** to advance 2D material research,includingthe optimization of graphene,MXenes,and TMDs synthesis for electrochemical applications,this compilation charts a coursetoward data-driven *** bridging experimental and machine learning approaches,it promises to reshape the landscape ofknowledge in electrochemistry,offering a transformative resource for the academic community.

关键词： Liquid Phase Exfoliation 2D Materials Transition Metal Dichalcogenides TMDs Size Selection Electrochemistry Energy Storage Ionic Sieving Machine Learning

Characterization of Wastewater in School Environments for an Ecological Treatment Solution: A Case Study of Ndiebene Gandiol 1 School

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Journal of Water Resource and Protection 2024年第1期16卷 27-40页

作者： Falilou Coundoul Abdou Khafor Ndiaye Abdoulaye Deme Polytechnic Institute of Saint-Louis Gaston Berger University Saint-Louis Sénégal Applied Sciences and Technologies Training and Research unit Gaston Berger University Saint-Louis Sénégal

The study conducted at Ndiebene Gandiol 1 school in Senegal has unveiled serious environmental and public health challenges. The wastewater analysis revealed high levels of Biochemical Oxygen Demand (BOD5), Chemical Oxygen Demand (COD), and fecal coliforms, signaling potential risks to the well-being of students and staff. This situation mirrors a wider issue in rural educational settings, where inadequate sanitation persists. Intensive wastewater treatment options are known for their effectiveness against high pollutant loads but are resource-intensive in both energy and cost. Conversely, extensive treatment systems, while requiring more land, provide a sustainable alternative by harnessing natural processes for pollutant removal. The research suggests a hybrid treatment approach could serve the school’s needs, balancing the robust capabilities of intensive methods with the ecological benefits of extensive systems. Such a solution would need to be tailored to the specific environmental, financial, and logistical context of the school, based on comprehensive feasibility studies and stakeholder engagement. This study’s findings underscore the urgency of addressing sanitation in schools, as it is intrinsically linked to the health and academic success of students. Quick, effective, and long-term strategies are vital to secure a healthier and more prosperous future for the youth. With proper implementation, the school can transform its sanitation facilities, setting a precedent for rural educational institutions in Senegal and similar contexts globally.

关键词： Wastewater Characterization Ecological Treatment School Sanitation Phytoremediation Rural Infrastructure Environmental Health

Effects of ginkgo flavone aglycone on atherosclerosis based on network pharmacology,molecular docking,and in vitro experiments

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TMR Modern Herbal Medicine 2024年第2期7卷 1-10页

作者： Miao Zhou Rui Li Qin Li Yan-Li Huang Shi-Jing Liu Ji-Yu Chen Yan He Animal Core Facility Nanjing Medical UniversityNanjing 211166China The Animal Experimental Center China Pharmaceutical UniversityNanjing 211166China Clinical Trials Center The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550000China Key Laboratory of Basic Pharmacology of Ministry of Education Zunyi Medical UniversityZunyi 563000China Office of academic Research The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550000China

Background:Ginkgo flavone aglycones(GA),a Ginkgo(Ginkgo biloba)extract,has been proven to have good biological activity in atherosclerosis(AS)***,its active compounds and the corresponding mechanism for the treatment of AS remain ***:To evaluate and identify the potential pharmacological mechanisms of GA in AS treatment,the program Cytoscape was used to generate network mappings of the GA-AS-potential target *** and KEGG enrichment analyses were performed to further investigate the potential mechanism of AS and the pharmacological properties of GA.A molecular docking approach was utilized to determine the GA components that interact with *** vitro experiments were carried out to identify the anti-atherosclerotic effects of GA by targeting ***:Network pharmacological research determined that the active components of GA(quercetin,kaempferol,and isorhamnetin)correlated with AS target genes such as AKT1,EGFR,SRC,ESR1,PTGS2,MMP9,KDR,GSK3B,APP,and MMP2,*** enrichment and KEGG analysis showed that PI3K-Akt signaling may play an important role in GA *** docking experiments indicated that quercetin,kaempferol,and isorhamnetin integrate into the binding pockets of the most potentially beneficial GA-AS target protein(Akt).Consequently,cell experiments were conducted to support the anti-atherosclerotic activity of GA on AS by inhibiting the phosphorylation of AKT1 and its downstream signaling molecules,which regulated the proliferation of ***:Our results detailed GA's active ingredients,potential targets,and molecular basis against *** may exert anti-atherosclerotic effects by suppressing Akt phosphorylation and inhibiting the proliferation of *** also proposed a viable approach to determining the scientific foundation and therapeutic mechanism of Chinese herbal medicine extracts in disease therapy.

关键词： network pharmacology ginkgo flavone aglycones atherosclerosis molecular docking kaempferol quercetin isorhamnetin

Learning from parental experience in a neonatal surgical unit:a qualitative service evaluation

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World Journal of Pediatric Surgery 2023年第3期6卷 147-153页

作者： Anna Littlejohns Emile Crouzen Rebecca Mernenko Fiona Metcalfe Waaka Moni-Nwinia Hemma Chauhan Bethan Johnson Douglas McConachie Elizabeth Lawson Victoria Tricklebank John G McElwaine Gurdeep S Sagoo Liz McKechnie Gary Latchford Jonathan Sutcliffe Anaesthesia and Critical care Leeds Teaching Hospitals NHS TrustLeedsUK Paediatric Surgery Leeds Children's HospitalLeedsUK Leeds Centre for Newborn care Leeds Children's HospitalLeedsUK Faculty of Medicine and Health University of LeedsLeedsUK academic unit of Health Economics University of LeedsLeedsUK Institute of Health Sciences University of Leeds LeedsLeedsUK St James's University Hospital Department of Clinical and Health Psychology LeedsUK

Objectives Patient experience is directly related to health outcomes,and parental experience can be used as a proxy for this in neonatal *** project was designed to assess parental experience of neonatal surgical care to inform future service developments and improve the care we *** This was a qualitative study using rapid qualitative *** study was carried out in a large neonatal surgical intensive care unit in the *** of infants treated by the neonatal surgical team between March 2020 and February 2021,during the COVID-19 pandemic were *** sampling was used to ensure that a representative range of parents were interviewed.A semistructured interview was created and tested in a previous phase of *** questionnaire was used to ask parents open questions about different aspects of their infants’healthcare journey from the antenatal phase through to discharge from the neonatal unit(NUU).Results Rapid qualitative analysis was employed,and parental experiences were grouped into five main categories:before admission to the NNU,initial admission to NNU,information and support,COVID-19 and *** these five groups,we highlighted positive experiences to be fed back to the healthcare teams to reinforce good practice,areas that warranted improvement and suggestions for service *** The wealth of data generated from the interviews has been summarized and shared with healthcare teams who are putting the service improvement suggestions into *** tool is available for services that wish to measure parental experience.

关键词： qualitative service interview

The Effectiveness of Antiviral Treatment in Severe COVID-19 Patients in Wuhan,China:A Multicenter Study

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Biomedical and Environmental Sciences 2022年第1期35卷 58-63页

作者： ZHOU Xian Long DING Guo Yong YANG Lu Yu LIU Rui Ning HOU Hai Feng WANG Ping MA Min HU Zhuan Zhuan HUANG Lei XU Xi Zhu HU Quan ZHAO Yan XING Wei Jia ZHAO Zhi Gang Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina School of Public Health Shandong First Medical University&Shandong Academy of Medical SciencesTai’an 271016ShandongChina Intensive care unit Wuhan Third HospitalWuhan 430060HubeiChina Intensive care unit Huazhong University of Science and Technology Union Jiangbei HospitalWuhan 430100HubeiChina Intensive care unit The first people's Hospital of Jiangxia DistrictWuhan 430200HubeiChina Hubei Clinical Research Center for Emergency and Resuscitation Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina

Coronavirus disease 2019(COVID-19)has inarguably caused the most challenging *** less than 2 years,greater than 200 million cases of COVID-19 and 4.5 million deaths have been reported worldwide[1].The treatment strategy of an emerging infectious disease is a huge challenge for clinical practitioners because of missing key knowledge about the disease.

关键词： Patients clinical COV

Post-tuberculosis lung disease and chronic obstructive pulmonary disease

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Chinese Medical Journal 2023年第16期136卷 1923-1928页

作者： Xiaoyan Gai Brian Allwood Yongchang Sun Department of Respiratory and Critical care Medicine Peking University Third HospitalCenter for Chronic Airway DiseasesPeking University Health Science CenterPeking UniversityBeijing 100191China Division of Pulmonology Department of MedicineStellenbosch University&Tygerberg Academic HospitalCape TownSouth Africa

The burden of chronic airway diseases,including chronic obstructive pulmonary disease(COPD),continues to increase,especially in low-and middle-income ***-tuberculosis lung disease(PTLD)is characterized by chronic lung changes after the"cure"of pulmonary tuberculosis(TB),which may be associated with the pathogenesis of ***,data on its prevalence,clinical manifestations,computed tomography features,patterns of lung function impairment,and influencing factors are *** pathogenic mechanisms underlying PTLD remain to be *** review summarizes the recent advances in PTLD and TB-associated *** is urgently needed both for the prevention and management of PTLD.

关键词： Tuberculosis Post-tuberculosis lung disease Chronic obstructive pulmonary disease

COVID-19 vaccination and diabetic ketoacidosis

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World Journal of Diabetes 2023年第5期14卷 560-564页

作者： Beuy Joob Viroj Wiwanitkit academic Center Sanitation1 Medical Academic CenterBangkok 1033300Thailand Community Medicine DY Patil VidhyapeethPune 233230India

An efficient coronavirus disease 2019(COVID-19)vaccine is urgently required to fight the pandemic due to its high transmission rate and quick *** have been numerous reports on the side effects of the COVID-19 immunization,with a focus on its negative *** endocrinology is extremely interested in the endocrine issue that arises after receiving the COVID-19 *** was already mentioned,after receiving the COVID-19 vaccine,many clinical problems could ***,there are some compelling reports on *** receiving the COVID-19 vaccine,a patient experienced hyperosmolar hyperglycemia state,a case of newly-onset type 2 *** has also been information on a potential connection between the COVID-19 vaccine and diabetic *** symptoms include thirst,polydipsia,polyuria,palpitations,a lack of appetite,and *** extremely rare clinical circumstances,a COVID-19 vaccine recipient may develop diabetes complications such as hyperglycemia and *** these circumstances,routine clinical care has a successful track *** is advised to give vaccine recipients who are vulnerable to problems,such as those with type 1 diabetes as an underlying illness,extra attention.

关键词： Diabetes COVID-19 Vaccine Ketoacidosis Effect