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Chinese Chemical Letters 2024年第6期35卷 274-278页

作者： Huan Yao Jian Qin Yan-Fang Wang Song-Meng Wang Liu-Huan Yi Shi-Yao Li Fangfang Du Liu-Pan Yang Li-Li Wang School of Pharmaceutical Science Postdoctoral Research Station of Basic MedicineHengyang Medical SchoolUniversity of South ChinaHengyang 421001China Department of Chemistry Southern University of Science and TechnologyShenzhen 518055China

Artificial macrocycle with high binding selectivity in water is often challenging but urgently needed in various research and application ***,we report a new water-soluble biomimetic tetralactam macrocycle and realize the ultra-high selectivity to nucleosides over corresponding monophosphate nucleotides by rational *** introduction of charged groups at the periphery of endofunctionalized cavity makes the selectivity(guanosine to guanosine 5-monophosphate)increase remarkably from 100 to *** on the ultra-high selectivity of biomimetic tetralactam macrocycle,the sensitive CD73 enzyme activity assay was then achieved through product-selective fluorescence indicator displacement ***,the capability of the proposed method for inhibitor screening was successfully displayed.

关键词： Rational modification Biomimetic macrocycle Ultra-high selectivity Enzyme assay

Assessment of coastal and mangrove vulnerability in the Andaman Island,Indian Ocean

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Geoscience Frontiers 2024年第5期15卷 47-60页

作者： Biswajit Mondal Rupesh K.Bhomia Ashis Kumar Saha Richard A.MacKenzie Department of Geography Delhi School of EconomicsUniversity of DelhiDelhi 110007India Centre for International Forestry research(CIFOR) Jalan CIFORSitu GedeBogor BaratBogor 16115Indonesia Institute of Pacific Islands Forestry Pacific Southwest Research StationUSDA Forest ServiceHiloHI 96720USA

Coastal regions are highly susceptible to the effects of global warming,including rising atmospheric and sea surface temperatures,increased cyclone frequency,and sea level ***,it is imperative to examine coastal vulnerability to minimize the impact of multiple hazards and protect coastal resources,such as *** in India studying the vulnerability of coastal zones of Andaman and Nicobar Islands which fall in seismic zone V is critical for conservation *** conducted a vulnerability analysis of coastal zones impacted by the 2004 earthquake,causing varying degrees of ground upliftment and *** compared coastal vulnerability among sites that experienced uplift,no change,and subsidence(the southern portion).Our analysis utilized the Coastal and Mangrove Vulnerability Index(CVI and MVI)to measure and compare vulnerability in six zones distributed along uplift and subsidence ***-resolution satellite imagery including WorldView-2,3,and GeoEye-1 from year 2022 are utilized on this *** CVI and MVI offers a good way to measure and compare vulnerabilities across sites and offer insights for better *** CVI and MVI results indicate that approximately 34%of coastal grids and over 23%of mangrove grids across all zones are highly to extremely highly *** zones were found to be more vulnerable than uplifted *** findings suggest that large-scale natural disturbances such as tectonic displacement have the potential to impact coastal vegetation and mangrove cover can become even more *** conclusion,our study emphasizes the importance of vulnerability analyses in coastal regions,especially in areas prone to seismic *** findings have direct implications for conservation and restoration efforts and underscore the need for continued monitoring and mitigation efforts to safeguard coastal resources for long-term sustainability.

关键词： Mangroves Coastal vulnerability Mangrove vulnerability 2004 Indian Ocean earthquake Andaman Island

Genetic analysis and candidate gene identification of salt tolerancerelated traits in maize

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Journal of Integrative Agriculture 2024年第7期23卷 2196-2210页

作者： Hui Fang Xiuyi Fu Hanqiu Ge Mengxue Jia Jie Ji Yizhou Zhao Zijian Qu Ziqian Cui Aixia Zhang Yuandong Wang Ping Li Baohua Wang Scientific Observing and Experimental station of Maize in Plain Area of southern Region Ministry of Agriculture and Rural Affairs/School of Life SciencesNantong UniversityNantong 226019China Maize research Institute Beijing Academy of Agriculture and Forestry Sciences(BAAFS)Beijing 100097China

Soil salinization poses a threat to maize production worldwide,but the genetic mechanism of salt tolerance in maize is not well ***,identifying the genetic components underlying salt tolerance in maize is of great *** the current study,a teosinte-maize BC2F7 population was used to investigate the genetic basis of 21 salt tolerance-related *** total,125 QTLs were detected using a high-density genetic bin map,with one to five QTLs explaining 6.05–32.02%of the phenotypic variation for each *** total phenotypic variation explained(PVE)by all detected QTLs ranged from 6.84 to 63.88%for each *** all 125 QTLs,only three were major QTLs distributed in two genomic regions on chromosome 6,which were involved in three salt tolerance-related *** addition,10 pairs of epistatic QTLs with additive effects were detected for eight traits,explaining 0.9 to 4.44%of the phenotypic ***,18 QTL hotspots affecting 3–7 traits were *** one hotspot(L5),a gene cluster consisting of four genes(ZmNSA1,SAG6,ZmCLCg,and ZmHKT1;2)was found,suggesting the involvement of multiple pleiotropic ***,two important candidate genes,Zm00001d002090 and Zm00001d002391,were found to be associated with salt tolerance-related traits by a combination of linkage and marker-trait association ***00001d002090 encodes a calcium-dependent lipid-binding(CaLB domain)family protein,which may function as a Ca^(2+)sensor for transmitting the salt stress signal downstream,while Zm00001d002391 encodes a ubiquitin-specific protease belonging to the C19-related *** findings provide valuable insights into the genetic basis of salt tolerance-related traits in maize and a theoretical foundation for breeders to develop enhanced salt-tolerant maize varieties.

关键词： maize salt tolerance-related traits QTL mapping region-based association analysis

Fast spreading of surface ozone in both temporal and spatial scale in Pearl River Delta

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Journal of Environmental Sciences 2024年第3期137卷 540-552页

作者： Tianhui Cao Haichao Wang Lei Li Xiao Lu Yiming Liu Shaojia Fan School of Atmospheric Sciences Sun Yat-sen University and Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Guangdong Provincial Observation and research station for Climate Environment and Air Quality Change in the Pearl River Estuary Key Laboratory of Tropical Atmosphere-Ocean SystemMinistry of EducationZhuhai 519082China

Surface ozone(O_(3))is a major air pollutant and draw increasing attention in the Pearl River Delta(PRD),***,we characterize the spatial-temporal variability of ozone based on a dataset obtained from 57 national monitoring sites during *** results show that:(1)the seasonal difference of ozone distribution in the inland and coastal areas was significant,which was largely affected by the wind pattern reversals related to the East Asian monsoon,and local ozone production and destruction;(2)the daily maximum 8hr average(MDA8 O_(3))showed an overall upward trend by 1.11 ppbv/*** the trends in the nine cities varied differently by ranging from-0.12 to 2.51 ppbv/*** hot spots of ozone were spreading to southwestern areas from the central areas since *** ozone is becoming a year-round air pollution problem with the pollution season extending to winter and spring in PRD region.(3)at the central and southwestern PRD cities,the percentage of exceedance days from the continuous type(defined as≥3 days)was ***,the ozone concentration of continuous type was much higher than that of scattered exceedance type(<3 days).In addition,although the occurrence of continuous type starts to decline since2017,the total number of exceedance days during the continuous type is *** results indicate that it is more difficult to eliminate the continuous exceedance than the scatter pollution days and highlight the great challenge in mitigation of O_(3)pollution in these cities.

关键词： Surface ozone pollution Ozone trend Spatial and temporal variability Pearl River Delta Pollution mitigation

Aqueous-phase formation of N-containing secondary organic compounds affected by the ionic strength

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Journal of Environmental Sciences 2024年第4期138卷 88-101页

作者： Yuqi Gan Xiaohui Lu Shaodong Chen Xinghua Jiang Shanye Yang Xiewen Ma Mei Li Fan Yang Yewen Shi Xiaofei Wang Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention Department of Environmental Science and EngineeringFudan UniversityShanghai 200433China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China Guangdong Provincial Observation and research station for Coastal Atmosphere and Climate of the Great Bay Area Southern University of Science and TechnologyShenzhen 518055China Institute of Mass Spectrometry and Atmospheric Environment Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air PollutionJinan UniversityGuangzhouChina Environmental Monitoring station of Pudong New District Shanghai 201200China Shanghai Municipal Center for Disease Control&Prevention Shanghai 200336China

The reaction of carbonyl-to-imine/hemiaminal conversion in the atmospheric aqueous phase is a critical pathway to produce the light-absorbing N-containing secondary organic compounds(SOC).The formation mechanism of these compounds has been wildly investigated in bulk solutions with a low ionic ***,the ionic strength in the aqueous phase of the polluted atmosphere may be *** is still unclear whether and to what extent the inorganic ions can affect the SOC *** we prepared the bulk solution with certain ionic strength,in which glyoxal and ammonium were mixed to mimic the aqueous-phase *** characterization by High-resolution Mass Spectrometry was performed to identify the N-containing products,and the light absorption of the mixtures was measured by ultraviolet-visible ***-nine N-containing compounds were identified and divided into four categories(N-heterocyclic chromophores,high-molecular-weight compounds with N-heterocycle,aliphatic imines/hemiaminals,and the unclassified).It was observed that the longer reaction time and higher ionic strength led to the formation of more N-heterocyclic chromophores and the increasing of the lightabsorbance of the *** added inorganic ions were proposed to make the aqueous phase somewhat viscous so that the molecules were prone to undergo consecutive and intramolecular reactions to form the *** general,this study revealed that the enhanced ionic strength and prolonged reaction time had the promotion effect on the lightabsorbing SOC *** implies that the aldehyde-derived aqueous-phase SOC would contribute more light-absorbing particulate matter in the industrial or populated area where inorganic ions are abundant.

关键词： Ionic strength Carbonyl-to-imine/hemiaminal Heterocyclic Brown carbon Mass spectrometry Aqueous-phase reaction

Seismicity changes and numerical simulation of coseismic deformation following the 2022 M_(s)6.8 Luding earthquake in Sichuan,China

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Science China Earth Sciences 2024年第8期67卷 2507-2521页

作者： Qiu MENG Zitao WANG Huai ZHANG Key Laboratory of Computational Geodynamics of Chinese Academy of Sciences College of Earth and Planetary SciencesUniversity of Chinese Academy of SciencesBeijing 100049China Institute of Earthquake Forecasting China Earthquake AdministrationBeijing 100036China southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519080China Beijing Yanshan Earth Critical Zone National research station Beijing 101408China

The Xianshuihe fault is a major tectonic boundary between the Sichuan-Yunnan rhombic and Bayanhar blocks in Southwest *** an average left-lateral strike-slip movement of 10–15 mm/yr,it is a fast-moving strike-slip continental *** September 5,2022,the Ms6.8 Luding earthquake occurred along the Moxi segment of the Xianshuihe fault,reaching a maximum intensity of IX and resulting in a significant number of casualties and severe property *** earthquake broke the long-standing seismic quiescence of the Xianshuihe fault,which lasted for more than 40 years,and was followed by a significant number of *** outstanding question is how the behavior of the Xianshuihe fault and major earthquakes changed following this *** this study,we examined the changes in regional seismicity following the Luding earthquake and identified the potential for future strong earthquakes along the Xianshuihe *** used a finite element numerical method to simulate the environment of the seismogenic fault and its adjacent *** addition,we used the coseismic slip model of the Luding earthquake with the split-node method to calculate how the stress and strain fields in the surrounding area were affected by the2022 *** stress changes were resolved in the main faults,and the seismicity of adjacent faults was analyzed in conjunction with the observed seismic *** results indicate that regional tectonic movement primarily occurred to the southeast along the Moxi *** stress field is approximately north-south in tension and east-west in *** in the stress field in the epicentral region of the Luding earthquake exceeded 1 *** maximum displacement of the coseismic deformation field was concentrated between Moxi town and Tuanjie village,and the Coulomb stress of the fault zone in this region experienced the largest ***,the b-value of the Gutenberg-Richter magnitude-frequency relationship at the epicenter a

关键词： Luding earthquake Seismicity Coulomb failure stress change Finite element numerical simulation

Longitudinal dependence of the forecast accuracy of the ionospheric total electron content in the equatorial zone

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Geodesy and Geodynamics 2024年第5期15卷 528-541页

作者： Artem Kharakhashyan Olga Maltseva Institute for Physics Southern Federal University344090Russia

The longitudinal dependence of the behavior of ionospheric parameters has been the subject of a number of works where significant variations are *** also applies to the prediction of the ionospheric total electron content(TEC),which neural network methods have recently been widely ***,the results are mainly presented for a limited set of *** paper examines the longitudinal dependence of the TEC forecast accuracy in the equatorial *** this case,the methods are used that provided the best accuracy on three meridians:European(30°E),Southeastern(110°E)and American(75°W).Results for the stations considered are analyzed as a function of longitude using the Jet Propulsion Laboratory Global Ionosphere Map(JPL GIM)for *** results are for 2 h ahead and 24 h ahead *** was found that in this case,based on the metric values,three groups of architectures can be *** first group included long short-term memory(LSTM),gated recurrent unit(GRU),and temporal convolutional networks(TCN)models as a part of unidirectional deep learning models;the second group is based on the recurrent models from the first group,which were supplemented with a bidirectional algorithm,increasing the TEC forecasting accuracy by 2-3 *** third group,which includes the bidirectional TCN architecture(BiTCN),provided the highest *** this architecture,according to data obtained for 9 equatorial stations,practical independence of the TEC prediction accuracy from longitude was observed under the following metrics(Mean Absolute Error MAE,Root Mean Square Error RMSE,Mean Absolute Percentage Error MAPE):MAE(2 h)is 0.2 TECU approximately;MAE(24 h)is 0.4 TECU approximately;RMSE(2 h)is less than 0.5 TECU except Niue station(RMSE(2 h)is 1 TECU approximately);RMSE(24 h)is in the range of 1.0-1.7 TECU;MAPE(2 h)station,MAPE(24 h)stations that formed latitudinal chains in the

关键词： Ionosphere Total electron content Forecasting BiGRU BiLSTM BiTCN Temporal convolution

Mandarin fish von Hippel-Lindau protein regulates the NF-κB signaling pathway via interaction with IκB to promote fish ranavirus replication

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Zoological research 2024年第5期45卷 990-1000页

作者： Zhi-Min Li Xiao-Wei Qin Qi Zhang Jian He Min-Cong Liang Chuan-Rui Li Yang Yu Weng-Hui Liu Shao-Ping Weng Jian-Guo He Chang-Jun Guo School of Marine Sciences State Key Laboratory for BiocontrolSouthern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Guangdong Province Key Laboratory of Aquatic Economic Animals&Guangdong Provincial Observation and Research Station for Marine Ranching of the Lingdingyang BaySun Yat-sen UniversityGuangzhouGuangdong 510275China Guangdong Laboratory for Lingnan Modern Agriculture South China Agricultural UniversityGuangzhouGuangdong 510640China

The von Hippel-Lindau tumor suppressor protein(VHL),an E3 ubiquitin ligase,functions as a critical regulator of the oxygen-sensing pathway for targeting hypoxia-inducible *** evidence suggests that mammalian VHL may also be critical to the NF-κB signaling pathway,although the specific molecular mechanisms remain ***,the roles of mandarin fish(Siniperca chuatsi)VHL(scVHL)in the NF-κB signaling pathway and mandarin fish ranavirus(MRV)replication were *** transcription of scVHL was induced by immune stimulation and MRV infection,indicating a potential role in innate ***-luciferase reporter gene assays and reverse transcription quantitative PCR(RT-qPCR)results demonstrated that scVHL evoked and positively regulated the NF-κB signaling *** with NF-κB signaling pathway inhibitors indicated that the role of scVHL may be mediated through scIKKα,scIKKβ,scIκBα,or ***-immunoprecipitation(Co-IP)analysis identified scIκBαas a novel target protein of ***,scVHL targeted scIκBαto catalyze the formation of K63-linked polyubiquitin chains to activate the NF-κB signaling *** MRV infection,NF-κB signaling remained activated,which,in turn,promoted MRV *** findings suggest that scVHL not only positively regulates NF-κB but also significantly enhances MRV *** study reveals a novel function of scVHL in NF-κB signaling and viral infection in fish.

关键词： VHL NF-κB IκBα Ranavirus Mandarin fish

Genetics of biochemical attributes regulating morpho-physiology of upland cotton under high temperature conditions

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Journal of Cotton research 2024年第1期7卷 29-44页

作者： MAJEED Sajid CHAUDHARY Muhammad Tanees MUBARIK Muhammad Salman RANA Iqrar Ahmad SHABAN Muhammad TAN Daniel KY JIA Yinhua DU Xiongming HINZE Lori AZHAR Muhammad Tehseen Federal Seed Certification and Registration Department Ministry of National Food Security and ResearchIslamabad 44090Pakistan Horticultural research Institute National Agricultural Research CentreIslamabad 44000Pakistan Department of Biotechnology University of NarowalNarowal 51600Pakistan Centre of Agricultural Biochemistry and Biotechnology University of AgricultureFaisalabad 38400Pakistan Department of Plant Breeding and Genetics University of Agriculture FaisalabadSub-Campus BurewalaVehariPakistan Faculty of Science School of Life and Environ-mental SciencesPlant Breeding InstituteSydney Institute of AgricultureThe University of SydneySydneyNSW 2006Australia State Key Laboratory of Cotton Biology Institute of Cotton Research of Chinese Academy of Agri-cultural ScienceAnyang 455000China Agricultural research Service USDASouthern Plains Agricultural Research CentreCollege StationTX 77845USA Department of Plant Breeding and Genetics University of AgricultureFaisal-abad 38400Pakistan School of Agriculture Sciences Zhengzhou UniversityZhengzhou 450000China.

Background Cotton is a strategically important fibre crop for global textile *** profoundly impacts several countries’industrial and agricultural *** cotton production is continuously threatened by the unpre-dictable changes in climate,specifically high *** heat-tolerant,high-yielding cotton cultivars with wide adaptability to be grown in the regions with rising temperatures is one of the primary objectives of modern cotton breeding ***,the main objective of the current study is to figure out the effective breed-ing approach to imparting heat tolerance as well as the judicious utilization of commercially significant and stress-tolerant attributes in cotton ***,the two most notable heat-susceptible(FH-115 and NIAB Kiran)and tolerant(IUB-13 and GH-Mubarak)cotton cultivars were spotted to develop filial and backcross populations to accom-plish the preceding study *** heat tolerant cultivars were screened on the basis of various morphological(seed cotton yield per plant,ginning turnout percentage),physiological(pollen viability,cell membrane thermostabil-ity)and biochemical(peroxidase activity,proline content,hydrogen peroxide content)*** The results clearly exhibited that heat stress consequently had a detrimental impact on every studied plant trait,as revealed by the ability of crossing and their backcross populations to tolerate high ***,when considering overall yield,biochemical,and physiological traits,the IUB-13×FH-115 cross went over particularly well at both normal and high temperature ***,overall seed cotton yield per plant exhibited a posi-tive correlation with both pollen viability and antioxidant levels(POD activity and proline content).Conclusions Selection from segregation population and criteria involving pollen viability and antioxidant levels concluded to be an effective strategy for the screening of heat-tolerant cotton g

关键词： Accessions Biochemical Breeding Cotton Generation mean analysis Heat stress

Summer Atmospheric Water Cycle under the Transition Influence of the Westerly and Summer Monsoon over the Yarlung Zangbo River Basin in the southern Tibetan Plateau

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Advances in Atmospheric Sciences 2024年第5期41卷 830-846页

作者： Qianhui MA Chunyan ZHANG Donghai WANG Zihao PANG School of Atmospheric Sciences Sun Yat-sen UniversityGuangdong Province Key Laboratory for Climate Change and Natural Disaster StudiesKey Laboratory of Tropical Atmosphere-Ocean SystemMinistry of EducationZhuhai 519082China southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China Guangdong Meteorological Data Center Guangdong Meteorological ServiceGuangzhou 510080China National Observation and research station of Coastal Ecological Environments in Macao Macao Environmental Research InstituteMacao University of Science and TechnologyMacao SAR 999078China National Meteorological Information Center China Meteorological AdministrationBeijing 100081China

This study compares the summer atmospheric water cycle,including moisture sources and consumption,in the upstream,midstream,and downstream regions of the Yarlung Zangbo River Basin in the southern Tibetan *** evolutions of moisture properties under the influence of the westerly and summer southerly monsoon are examined using 5-yr multi-source measurements and ERA5 reanalysis *** that moisture consumption in this study is associated with clouds,precipitation,and diabatic *** to the midstream and downstream regions,the upstream region has less moisture,clouds,and precipitation,where the moisture is brought by the *** early August,the vertical wet advection over this region becomes enhanced and generates more high clouds and *** midstream region has moisture carried by the westerly in June and by the southerly monsoon from July to *** higher vertical wet advection maximum here forms more high clouds,with a precipitation peak in early *** downstream region is mainly affected by the southerly-driven wet *** rich moisture and strong vertical wet advection here produce the most clouds and precipitation among the three regions,with a precipitation peak in late *** height of the maximum moisture condensation is different between the midstream region(325 hPa)and the other two regions(375 hPa),due to the higher upward motion maximum in the midstream *** diabatic heating structures show that stratiform clouds dominate the upstream region,stratiform clouds and deep convection co-exist in the midstream region,and deep convection systems characterize the downstream region.

关键词： Yarlung Zangbo River Basin atmospheric water cycle constrained variational analysis moisture source and consumption