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Organic matter produced by algae and cyanobacteria: Quantitative and qualitative characterization

Journal of Environmental Sciences 2013年第6期25卷 1089-1097页

作者： Maud Leloup Rudy Nicolau Virginie Pallier Claude Yprmian Geneviève Feuillade-Cathalifaud University of Limoges EA 4330Groupement de Recherche EauSolEnvironnement(GRESE)ENSILParc d'ESTER Technople16 rue AtlantisF-87068 Limoges CedexFrance umr 7245 mcam mnhn-cnrs Equipe CyanobactériesCyanotoxines et EnvironnementMuséum National d'Histoire NaturelleCase 3912 rue BuffonF-75231 Paris Cedex 05France

This work aims at characterizing organic matter produced by an alga Euglena gracil~ and a cyanobacteria Microcystis aeruginosa and assessing the evolution of its characteristics during growth. A culture medium was optimized. The species growth phases were monitored using both visible spectrophotometry and flow cytometry cell counting. Organic matter fractionation according to hydrophobicity and specific UV absorbance （SUVA） index were used to specifically characterize the produced algal organic matter （AOM）. The AOM characteristics were both growth phase and species dependent. However, a similar evolution was observed. The hydrophilic fraction （HPI） was the major fraction whatever the growth phases and was almost the only one produced during lag and exponential phases. It represented around 75% of AOM during exponential phase and then decreased when the stationary phase appeared. It represented 46% and 60% of the AOM during late decline phase for the cyanobacteria and the alga respectively. The hydrophobic （HPO） and transphilic （TPH） fractions started to appear from the beginning of the stationary phase with more hydrophobic compounds coming from intracellular organic material of dying cells. HPO and TPH percentages still increased during the decline phase probably because of two additional processes： photo-dissolution and leaching of particulate organic matter from cells fragments. A comparison of AOM during late decline phase and natural organic matter （NOM） from Glane River （France） underlined that AOM was more fiydrophilic and presented a lower SUVA for each fractions than NOM. However, the difference between NOM and AOM hydrophobicity narrowed during decline phase.

关键词： algae cyanobacteria organic matter XAD fractionation SUVA flow cytometry

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Palcernuine, the first [5/6/6/6]-cernuane-type alkaloid from Palhinhaea cernua ***

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Chinese Chemical Letters 2016年第6期27卷 969-973页

作者： Yu Tang Juan Xiong Yike Zou Bastien Nay Li-Jun Wang Jin-Feng Hu Department of Natural Products Chemistry School of PharmacyFudan UniversityShanghai 201203China Department of Chemistry University of PennsylvaniaPhiladelphia 19104-6323USA Unite Molecules de Communication et Adaptation des Micro-organismes Sorbonne UniversitesMuseum National d'Histoire NaturelleCentre National de la Recherche Scientifique(CNRS UMR 7245)Paris 75005France

One novel（named palcernuine, 1） and five known cernuane-type（2–6） alkaloids were isolated from the whole plant of Palhinhaea cernua f. sikkimensis. The structure of 1, possessing an unprecedented [5/6/6/6]-tetracyclic ring system containing two nitrogen atoms, was established on the basis of spectroscopic methods, and its absolute configuration was determined by comparison of the experimental and calculated electronic circular dichroism（ECD） spectra. A plausible biosynthetic pathway to 1 is proposed.

关键词： Palhinhaea cernua f.sikkimensis Lycopodiaceae Palcernuine Cernuane-type alkaloids Biosynthetic pathway

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欧洲心血管病一级预防中对血压控制的欠缺：欧洲心血管事件风险日常防范与管理研究结果

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中华高血压杂志 2016年第7期24卷 682-684页

作者： Borghi C Tubach F De Backer G Dallongeville J Guallar E Medina J Perk J Roy C Banegas JR Rodriguez-Artalejo F Halcox JP 黄邦邦 Department of Internal Medicine Ageing and Clinical Nephrology University of Bologna Bologna Italy Italy INSERM CIC-EC 1425 and Département d'Epidemiologie et Recherche Clinique Assistance Publique-Hopitaux de Paris Hopital Bichat Paris France Université Paris Diderot UMR 1123 ECEVE Paris France France Department of Public Health University of Ghent Ghent Belgium Belgium INSERM U 744 Institut Pasteur de Lille Université Lille-Nord de France France Departments of Epidemiology and Medicine and Welch Center of Prevention Epidemiology and Clinical Research Johns Hopkins Bloomberg School of Public Health Baltimore MD USA USA Medical Evidence and Observational Research AstraZeneca Madrid Spain Spain Faculty of Health and Caring Sciences Linnaeus University Kalmar Sweden Sweden INSERM CIC-EC 1425 and Département d'Epidemiologie et Recherche Clinique Assistance Publique-Hopitaux de Paris Hopital Bichat Paris France France Department of Preventive Medicine and Public Health School of Medicine Universidad Autónoma de Madrid/IdiPaz and CIBER of Epidemiology and Public Health (CIBERESP) Madrid Spain Spain Institute of Life Sciences 2 Swansea University College of Medicine Swansea UK UK

尽管近年来欧洲心血管病的死亡率有所下降,但每年约47%的死亡仍由心血管病引起。因此,心血管病的一级和二级预防十分重要。发生心血管事件的首要危险因素包括年龄、性别、吸烟、动脉高血压、血脂异常、糖尿病、肥胖及缺乏锻炼。

关键词：心血管病二级预防一级预防血脂异常敏感性分析控制率血清尿酸水平代谢综合征危险评估钙拮抗剂

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