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Global paleobiogeography of Albian—Cenomanian(mid-Cretaceous)marine ostracods

Journal of Palaeogeography 2024年第2期13卷 212-236页

作者： Bernardo Vázquez-García Jorge Villegas-Martín Gerson Fauth Leonardo Borghi Aristóteles De Moraes Rios Netto Post-Graduate Program in Geology Unisinos UniversitySao LeopoldoRSBrazil Technological Institute of Paleoceanography and Climate Change-Itt Oceaneon Unisinos UniversitySao LeopoldoRSBrazil Laboratory of Sedimentary Geology(Lagesed) Department of GeologyInstitute of GeosciencesUFRJ-Federal Universityof Riode JaneiroBrazil Labmicro Department of GeologyInstitute of GeosciencesUFRJ-Federal University of Rio de JaneiroBrazil

Despite their potential for providing important information for paleobiogeography,studies using ostracod assemblages compiled from global datasets have been scarce so *** this study,the paleogeographic implications of the relationship between different ostracod assemblages are analyzed and discussed for the Albian and *** compiled an ostracod dataset at the genus level,with 168 genera for the Albian and 174 for the Cenomanian,to which different multivariate statistical methods of grouping were *** affinity between different ostracod assemblages from different regions allowed for the delineation of 30 operational geographic units(OGUs)for the Albian,and 32 OGUs for the Cenomanian,grouped in three paleobiogeographic units(PBUs;Megatethys,Persia,and Austral)and one sub-unit(PBSU;Maghreb associated to the Megatethys).The Maghreb PBSU showed minor changes between the Albian and *** relationship among the OGUs grouped in each PBU is related to different factors,such as eustatic sea level events,similar climatic zones,and marine current circulation patterns.A relationship was observed between the Gabon and Nigeria OGUs with the Persia PBU,which suggests a direct east—west connection between them during the *** affinity observed in the Austral PBU between the South American,South African,and Australian regions during the Albian can be explained by their relative geographic isolation due to the Walvis Ridge *** eventual flooding of this barrier led to the relationship observed between the SE Brazilian and Bolivian regions with the Austral ***,the data also suggested that the separation of the Indian subcontinent from the Austral PBU took place during the Cenomanian.

关键词： Operational geographic units Paleobiogeographic units Albian Cenomanian Marine ostracods

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The impact of heterogeneity and pore network characteristics on single and multi-phase fluid propagation in complex porous media:An X-ray computed tomography study

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Petroleum Science 2024年第3期21卷 1719-1738页

作者： Shohreh Iraji Tales Rodrigues De Almeida Eddy Ruidiaz Munoz Mateus Basso Alexandre Campane Vidal Department of Mechanical Engineering(FEM) State University of Campinas(UNICAMP)CampinasSP13083-860Brazil Department of Geology and Natural Resources Geosciences Institute(IG)State University of Campinas(UNICAMP)CampinasSP.13083-855.Brazil LRAP/COPPE/COPPETEC/ufrj Rua Moniz Aragao 360Bloco 4 Cidade UniversitariaRio de Janeiro21941-594Brazil Center of Energy and Petroleum Studies(CEPETRO) State University of Campinas(UNICAMP)CampinasSP13083-896Brazil

This study investigates the impact of pore network characteristics on fluid flow through complex and heterogeneous porous media,providing insights into the factors affecting fluid propagation in such ***,high-resolution or micro X-ray computed tomography(CT)imaging techniques were utilized to examine outcrop stromatolite samples of the Lagoa Salgada,considered flow analogous to the Brazilian Pre-salt carbonate *** petrophysical results comprised two distinct stromatolite depositional facies,the columnar and the fine-grained *** generating pore network model(PNM),the study quantified the relationship between key features of the porous system,including pore and throat radius,throat length,coordination number,shape factor,and pore *** study found that the less dense pore network of the columnar sample is typically characterized by larger pores and wider and longer throats but with a weaker connection of throats to *** facies exhibited less variability in the radius of the pores and throats in comparison to throat ***,a series of core flooding experiments coupled with medical CT scanning was designed and conducted in the plug samples to assess flow propagation and saturation *** study revealed that the heterogeneity and presence of disconnected or dead-end pores significantly impacted the flow patterns and ***-phase flow patterns and oil saturation distribution reveal a preferential and heterogeneous displacement that mainly swept displaced fluid in some regions of plugs and bypassed it in *** relation between saturation profiles,porosity profiles,and the number of fluid flow patterns for the samples was *** for the columnar plug sample was the enhancement in recovery factor after shifting to lower salinity water injection(SB)observed.

关键词： Pore network model Heterogeneous porous media Flow patterns Dead-end pores

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Z-Score in Fetal Echocardiography–Is there Still Room for New Studies?

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Congenital Heart Disease 2024年第3期19卷 305-314页

作者： Marcio Fragoso Vieira Nathalie Jeanne Bravo-Valenzuela Edward Araujo Júnior Department of Obstetrics Paulista School of MedicineFederal University of São Paulo(EPM-UNIFESP)São Paulo-SP04023-062Brazil Department of Obstetrics Federal University of Ceará(UFC)Sobral-CE60020-181Brazil Department of Pediatrics Pediatric CardiologySchool of MedicineFederal University of Rio de Janeiro(UFRJ)Rio de Janeiro-RJ21941-853Brazil

Congenital heart disease(CHD)is the most common type of birth defect,representing a significant cause of peri-natal morbidity and *** diagnosis of such anomalies is crucial for improving *** pro-tocols recommend a qualitative assessment of cardiac structures using two-dimensional ultrasound(2DUS)and color Doppler *** cases of suspected abnormalities,quantitative assessments through cardiac structure measurements and reference curves can aid in accurate *** to centiles widely employed in obste-trics,Z-scores provide more precise quantification of various cardiac structures,particularly at the extremes of the *** the development of reference curves and Z-scores has progressed over the past two decades,a lack of standardization in measurements and statistical methodology for their determination is *** reference curves requires adherence to specific recommendations to improve their *** purpose of this study is to provide a narrative review of the major studies that have generated reference values for cardiac struc-tures using 2DUS and Z-scores,to evaluate their methodology,and to provide a summary of the results.

关键词： Z-scores reference ranges fetal echocardiography

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Harnessing marine microbiomes to develop a sustainable,all-Atlantic bioeconomy

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mLife 2024年第2期3卷 163-166页

作者： Cristiane Thompson Alice C.Ortmann Henk Bolhuis Thulani Makhalanyane Fabiano Thompson Institute of Biology Federal University of Rio de Janeiro(UFRJ)Rio de JaneiroBrazil Fisheries and Oceans Canada Bedford Institute of OceanographyDartmouthNova ScotiaCanada Department of Marine Microbiology and Biogeochemistry Royal Netherlands Institute for Sea Research(NIOZ)The Netherlands Department of Microbiology School of Data Science and Computational ThinkingStellenbosch UniversityStellenboschSouth Africa

Marine microbiomes are integral to the functioning of a healthy ocean and have the potential to be key contributors toward an all-Atlantic sustainable blue bioeconomy(Figure 1).New compounds may be developed based on these *** Atlantic Ocean is a biodiversity *** All-Atlantic Ocean Research and Innovation Alliance(AAORIA)Declaration,signed in 2022 in Washington,DC,is a promising mechanism to move forward marine microbiome science,technology,and innovation.

关键词： Atlantic marine ocean

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Phenomenological model for torsional galloping of an elastic flat plate due to hydrodynamic loads

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Journal of Hydrodynamics 2014年第1期26卷 57-65页

作者： FERNANDES Antonio Carlos ARMANDEI Mohammadmehdi Department of Naval and Ocean Engineering COPPE/UFRJ

This study investigates the torsional galloping phenomenon, an instability type flow-induced oscillation, in an elastic stru-cture due to hydrodynamic loads into the water current. The structure applied here is a rectangular flat plate with an elastic axis in its mid-chord length. The elasticity is provided by torsion spring. The flat plate has only one degree of freedom which is rotation in pure yaw about its axis. It is observed that as the current speed is higher than a critical velocity, the flat plate becomes unstable. The instability leads to torsional galloping occurrence, as a result of which the flat plate begins to yaw about the elastic axis. By testing two different chord lengths each with several torsion spring rates, the flat plate behavior is investigated and three different responses are recognized. Then, a phenomenological model is developed with the original kernel in the form of the van der Pol-Duffing equa-tion. The model explains these three responses observed experimentally.

关键词： torsional galloping flow-induced oscillation phenomenological model van der Pol-Duffing equation

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Treatment of spinal cord injury with biomaterials and stem cell therapy in non-human primates and humans

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Neural Regeneration Research 2025年第2期20卷 343-353页

作者： Ana Milena Silva Olaya Fernanda Martins Almeida Ana Maria Blanco Martinez Suelen Adriani Marques PhD Program in Pathological Anatomy Federal University of Rio de JaneiroRio de JaneiroBrazil Biomedical Science Institute Federal University of Rio de JaneiroRio de JaneiroBrazil Graduate Program in Pathological Anatomy Federal University of Rio de JaneiroRio de JaneiroBrazil Graduate Program in Pathological Anatomy(PPGAP/ufrj) Department of Neurobiology/Institute of BiologyCampus do GragoatáNiteróiRio de JaneiroBrazil

Spinal cord injury results in the loss of sensory,motor,and autonomic functions,which almost always produces permanent physical ***,in the search for more effective treatments than those already applied for years,which are not entirely efficient,researches have been able to demonstrate the potential of biological strategies using biomaterials to tissue manufacturing through bioengineering and stem cell therapy as a neuroregenerative approach,seeking to promote neuronal recovery after spinal cord *** of these strategies has been developed and meticulously evaluated in several animal models with the aim of analyzing the potential of interventions for neuronal repair and,consequently,boosting functional *** the majority of experimental research has been conducted in rodents,there is increasing recognition of the importance,and need,of evaluating the safety and efficacy of these interventions in non-human primates before moving to clinical trials involving therapies potentially promising in *** article is a literature review from databases(PubMed,Science Direct,Elsevier,Scielo,Redalyc,Cochrane,and NCBI)from 10 years ago to date,using keywords(spinal cord injury,cell therapy,non-human primates,humans,and bioengineering in spinal cord injury).From 110 retrieved articles,after two selection rounds based on inclusion and exclusion criteria,21 articles were ***,this review arises from the need to recognize the experimental therapeutic advances applied in non-human primates and even humans,aimed at deepening these strategies and identifying the advantages and influence of the results on extrapolation for clinical applicability in humans.

关键词： bioengineering biomaterials cell therapy humans non-human primates spinal cord injury stem cell therapy

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Comparison of morphological and functional outcomes of mouse sciatic nerve repair with three biodegradable polymer conduits containing poly (lactic acid)

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Neural Regeneration Research 2018年第10期13卷 1811-1819页

作者： Fernanda Marques Pestana Rui C.C.Domingues Júlia Teixeira Oliveira Daniela F.P.A.Durco Camila Oliveira Goulart Henrique Rocha Mendonca Anne Caroline Rodrigues dos Santos Natália Tavares de Campos Beatriz Theodoro da Silva Cristina Cardoso Pereira Cristiano Piacsek Borges Ana Maria Blanco Martinez Pós Graduacao em Ciências Morfológicas Instituto de Ciências Biomédicas-UFRJRio de Janeiro RJ Brazil Anatomia Patológica-Faculdade de Medicina-HUCFF-ufrj Rio de Janeiro RJ Brazil Laboratório de Neurodegeneracao e Reparo-Faculdade de Medicina-HUCFF-ufrj Rio de Janeiro RJ Brazil Programa de Eng. Química COPPE-UFRJRio de Janeiro Brazil Polo Universitário de Macaé Laboratório Integrado de Produtos Bioativos e BiociênciasMacaê UFRJ Brazil

Poly（lactic acid）（PLA）-containing nerve guidance conduits（NGCs） are currently being investigated for nerve repair as an alternative to autograft, which leads to permanent functional impairment in the territory innervated by the removed nerve. Combination of polymers modifies the physical properties of the conduits, altering their nerve-guidance properties. Conduits made from PLA-only or combined with other polymers have been used successfully for nerve repair, but their efficiency has not been compared. We compared the morphological and functional outcomes of peripheral nerve repair by using NGCs made of poly（lactic acid） and combined or not with polycaprolactone（PLA/PCL） or polyvinylpyrrolidone（PLA/PVP）. To assess the functional recovery, we employed a mechanical hyperalgesia analysis, sciatic functional index（SFI）, and electroneuromyography. The mechanical hyperalgesia analysis showed that the PLA group improved more rapidly than the PLA/PVP and PLA/PCL groups; similarly, in the electroneuromyography assay, the PLA group exhibited higher amplitude than the PLA/PCL and PLA/PVP groups. However, the SFI improvement rates did not differ among the groups. Morphologically, the PLA group showed more vascularization, while the nerve fiber regeneration did not differ among the groups. In conclusion, the PLA-only conduits were superior to the other NGCs tested for nerve repair.

关键词： sciatic nerve tubulization biodegradable conduit poly(lactic acid) regeneration

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Phasor-domain Dynamic Model of Asymmetric Current Injection Controller for Converter-interfaced Generator

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Journal of Modern Power Systems and Clean Energy 2021年第6期9卷 1269-1278页

作者： Victor A.F.Almeida Glauco N.Taranto José M.T.Marinho Electrical Engineering Department of the Federal University of Rio de Janeiro(COPPE/ufrj) Petrobras S.A.

This paper presents a controller model of asymmetric current injection for converter-interfaced generators suitable for root-mean-square(RMS)phasor-domain,fundamentalfrequency,three-phase,and dynamic simulation *** effectiveness of the proposed controller is assessed with simulations in test systems with high percentage of converter-interfaced *** simulations focus on the operation of protection relays that use negative-sequence quantities in their directional *** paper also presents and compares two strategies to limit reactive negative-sequence currents,and active and reactive positive-sequence currents.A tutorial test system and a regional system part of the actual Brazilian Interconnected Power System are used to assess the correctness of the proposed controller in three-phase fundamental-frequency RMS dynamic simulations.

关键词： Converter-interfaced generator three-phase model power system protection negative-sequence current injection negative-sequence current protection unbalanced fault three-phase root-mean-square(RMS)dynamic simulation

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Stability analysis of the fluttering and autorotation of flow-induced rotation of a hinged flat plate

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Journal of Hydrodynamics 2013年第5期25卷 755-762页

作者： MIRZAEISEFAT Sina FERNANDES Antonio Carlos Department of Naval Architecture and Marine Engineering University of Michigan COPPE/ufrj Federal University of Rio de Janeiro

This work describes investigations performed on the interaction of uniform current and freely rotating plate about a fixed vertical axis. Fluttering and autorotation are two different motions that may occur during the flow induced rotation. The dimensional analysis proves that the motion in flow induced rotation motion is governed essentially by the dimensionless moment of inertia and Reynolds number. Certain combinations define the stability boundaries between fluttering and autorotation. Fluttering is oscillation of body about a vertical axis and the autorotation is a name given to the case when the body turns continuously about the vertical axis First, the loads and moment coefficients are calculated by experiments and streamline theory for different angles of attack for a fixed fiat plate. Then for dynamic case, a bifurcation diagram is presented based on experiments to classify different motion states of flow induced rotation. Finally, a dynamical model is proposed for stability analysis of flow induced rotation of a flat plate.

关键词： flow-induced rotation autorotation fluttering stability analysis

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Absence of galectin-3 attenuates neuroinflammation improving functional recovery after spinal cord injury

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Neural Regeneration Research 2016年第1期11卷 92-93页

作者： Caio Andrade Prins Fernanda Martins Almeida Ana Maria Blanco Martinez Laboratorio de Neurodegeneracao e Reparo-Departamento de Patologia-Faculdade de Medicina-HUCFF-ufrj-Rio de Janeiro-RJ Brazil Instituto de Ciencia Biomedicas UFRJRio de JaneiroRJBrazil

After spinal cord injury （SCI）, a cascade of events begins. At first, there is physical damage with disruption of the blood-brain barrier （BBB） and the integrity of the nervous tissue. The disruption of central ner- vous system （CNS） BBB alters the endothelial permeability, the protein and chemokines expression and the propensity to release in situ inflam- matory cytokines, overcoming anti-inflammatory signals, facilitating the attraction and entry of immune system cells into the injured spinal cord parenchyma （Gaudet et al., 2011）. As a result, there is a neuroin- flammatory response with changes in blood flow, edema, cell infiltra- tion, apoptosis and release of axonal growth inhibitory factors. Nerve function loss occurs when the nerve impulse propagation is interrupted and do not reach its target. This disorder encompasses neuron and glia apoptosis, accompanied by Wallerian degeneration of disconnected axons, and CNS cells exposure to a hostile microenvironment that hampers axon regeneration （Mautes et al., 2000; Harkey et al., 2003）.

关键词： galectin disruption permeability facilitating attraction cascade macrophages cytokines morphologic exposure

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