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Mechanism of Thermally Radiative Prandtl Nanofluids and Double-Diffusive Convection in Tapered Channel on Peristaltic Flow with Viscous Dissipation and Induced Magnetic Field

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Computer Modeling in engineering & Sciences 2024年第2期138卷 1501-1520页

作者： Yasir Khan Safia Akram Maria Athar Khalid Saeed Alia Razia A.Alameer department of Mathematics University of Hafr Al-BatinHafr Al-Batin31991Saudi Arabia MCS National University of Sciences and TechnologyIslamabadPakistan SEECS National University of Sciences and TechnologyIslamabadPakistan College of Aeronautical engineering National University of Sciences and TechnologyIslamabadPakistan

The application of mathematical modeling to biological fluids is of utmost importance, as it has diverse applicationsin medicine. The peristaltic mechanism plays a crucial role in understanding numerous biological flows. In thispaper, we present a theoretical investigation of the double diffusion convection in the peristaltic transport of aPrandtl nanofluid through an asymmetric tapered channel under the combined action of thermal radiation andan induced magnetic field. The equations for the current flow scenario are developed, incorporating relevantassumptions, and considering the effect of viscous dissipation. The impact of thermal radiation and doublediffusion on public health is of particular interest. For instance, infrared radiation techniques have been used totreat various skin-related diseases and can also be employed as a measure of thermotherapy for some bones toenhance blood circulation, with radiation increasing blood flow by approximately 80%. To solve the governingequations, we employ a numerical method with the aid of symbolic software such as Mathematica and *** velocity, magnetic force function, pressure rise, temperature, solute (species) concentration, and nanoparticlevolume fraction profiles are analytically derived and graphically displayed. The results outcomes are compared withthe findings of limiting situations for verification.

关键词： Double diffusion convection thermal radiation induced magnetic field peristaltic flow tapered asymmetric channel viscous dissipation Prandtl nanofluid

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A systematic understanding of microbial reductive dechlorination towards an improved “one health” soil bioremediation: A review and perspective

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Science China Technological Sciences 2024年第10期67卷 3009-3031页

作者： HE Yan LI ShuYao YUAN Jing CHENG Jie DOU JiBo YANG XueLing XU JianMing Zhejiang Provincial Key Laboratory of Agricultural Resources and Environment Institute of Soil and Water Resources and Environmental ScienceCollege of Environmental and Resource SciencesZhejiang University Key Laboratory of Environment Remediation and Ecological Health Ministry of Education Microbiome Network and department of Agricultural Biology Colorado State University departments of Chemistry and Chemical & Biomolecular engineering Institute for Functional Intelligent Materials (I-FIM)National University of Singapore

Chlorinated organic pollutants(COPs), both emerging and traditional, are typical persistent pollutants that harm soil health worldwide. Dechlorinators mediated reductive dechlorination is the optimal way to completely remove COPs from anaerobic soil through a redox reaction driven by electron transfer during microbial anaerobic respiration. Generally, the dechlorinated depletion of COPs in situ often interacts with multiple element biogeochemical activities, e.g., methanogenesis, sulfate reduction, iron reduction, and denitrification. Elucidating the relevance of biogeochemical cycles between COPs and multiple elements and the coupled mechanisms involved, thus, helps to develop effective pollution control strategies with the balance between pollution degradation and element cycles in heterogeneous soil, ultimately contributing to “one health” goal. In this review, we summarized the microbial-chemical coupling redox processes and the driving factors, elucidated the interspecies metabolites exchange and electron transfer mechanisms within COP-dechlorinating communities, and further proposed a detailed design, construction, and analysis framework of engineering COP-dechlorinating microbiomes via “top-down” selfassembly and “bottom-up” synthesis to pave the way from laboratory to practical field application. Especially, we delve into the major challenges and perspectives surrounding the design of state-of-the-art synthetic microbial communities. Our goal is to improve the understanding of the microbial-mediated coupling between reductive dechlorination and element biogeochemical cycling, with a particular focus on the implications for health-integrated soil bioremediation under the “one health” concept.

关键词： reductive dechlorination biogeochemical redox processes interspecies interaction synthetic microbiomes, anaerobic soils

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Experimental demonstration of a flexible-grid 1×(2×3)mode-and wavelength-selective switch using silicon microring resonators and counter-tapered couplers

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Chinese Optics Letters 2024年第1期22卷 52-58页

作者：孔德军鲁昊汪鹏君符强戴世勋陈伟伟王栎沣张波豪马凌霄李军戴庭舸杨建义 Faculty of Electrical engineering and Computer Science Ningbo UniversityNingbo 315211China College of Electrical and Electronic engineering Wenzhou UniversityWenzhou 325035China College of Science and Technology Ningbo UniversityNingbo 315300China Laboratory of Infrared Materials and Devices The Research Institute of Advanced TechnologiesNingbo UniversityNingbo 315211China department of Information Science and Electronics engineering and Cyrus Tang Center for Sensor Materials and Applications Zhejiang UniversityHangzhou 310027China

A flexible-grid 1×(2×3)mode-and wavelength-selective switch which comprises counter-tapered couplers and silicon microring resonators has been proposed,optimized,and demonstrated experimentally in this *** carefully thermally tuning phase shifters and silicon microring resonators,mode and wavelength signals can be independently and flexibly conveyed to any one of the output ports,and different bandwidths can be generated as *** particle swarm optimization algorithm and finite difference time-domain method are employed to optimize structural parameters of the twomode(de)multiplexer and crossing *** bandwidth-tunable wavelength-selective optical router composed of12 microring resonators is studied by taking advantage of the transfer matrix *** results show that,for the fabricated module,cross talk less than-10.18 dB,an extinction ratio larger than 17.41 d B,an in-band ripple lower than0.79 dB,and a 3-dB bandwidth changing from 0.38 to 1.05 nm are obtained,as the wavelength-channel spacing is 0.40 *** corresponding response time is measured to be 13.64μs.

关键词： integrated optics optical waveguide mode-and wavelength-selective switch

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Actively contractible and antibacterial hydrogel for accelerated wound healing

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Nano Research 2024年第8期17卷 7394-7403页

作者： Zhaoxin Ji Ting Wei Jiafei Zhu Jiaying Hu Zhisheng Xiao Boxiong Bai Xinying Lv Yu Miao Muchao Chen Cheng Wang Feng Pan Yang Yang Meng Li Qian Chen Institute of Functional Nano and Soft Materials Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesSoochow UniversitySuzhou 215123China department of Thoracic Surgery Shanghai Pulmonary HospitalSchool of MedicineTongji UniversityShanghai 200433China Central Laboratory Shanghai Pulmonary HospitalSchool of MedicineTongji UniversityShanghai 200433China School of Materials Science and engineering Tongji UniversityShanghai 201804China department of dermatology Shanghai Children’s Medical Center School of MedicineShanghai Jiao Tong UniversityShanghai 200025China

Adhesive hydrogel has drawn great attention for wide applications in wound healing owing to its excellent biocompatibility and lasting ***,traditional adhesive hydrogels only keep the wound moist to promote wound *** is still imperative to fabricate adhesive hydrogels that exhibit efficient antibacterial ability,active driving dynamic wound closure,and reactive oxygen species(ROS)scavenging together with excellent mechanical ***,a novel hydrogel based on poly(N-isopropyl acrylamide)(PNIPAAm),a thermoresponsive polymer,and tannic acid(TA)-Ag nanoparticles(TA-Ag NPs)exhibiting active contraction,tissue adhesion,anti-inflammatory and antibacterial functions was ***-Ag dispersed in the hydrogel not only functioned as the catalyst to polymerize the reaction but also provided additional anti-inflammatory and antibacterial ***,tannic acid containing catechol groups endowed the hydrogel with adhesive *** interestingly,the obtained hydrogel exhibited the thermoresponsive shrinkage ability,which could mechanically drive wound closure due to the presence of PNIPAAm *** vivo mouse full-thickness skin defect model demonstrated that this actively contractible and antibacterial hydrogel is a promising dressing to improve wound healing process by accelerating tissue regeneration and preventing bacterial ***,this multi-functional adhesive hydrogel developed here may provide a new possibility for wound healing.

关键词： anti-inflammatory antibacterial active contraction hydrogel patch wound healing

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Artificial intelligence enhances the management of esophageal squamous cell carcinoma in the precision oncology era

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World Journal of Gastroenterology 2024年第39期30卷 4267-4280页

作者： Wan-Yue Zhang Yong-Jian Chang Rui-Hua Shi School of Medicine Southeast UniversityNanjing 221000Jiangsu ProvinceChina School of Cyber Science and engineering Southeast UniversityNanjing 210009Jiangsu ProvinceChina department of Gastroenterology Zhongda HospitalSoutheast UniversityNanjing 210009Jiangsu ProvinceChina

Esophageal squamous cell carcinoma(ESCC)is the most common histological type of esophageal cancer with a poor *** diagnosis and prognosis assessment are crucial for improving the survival rate of ESCC *** the advancement of artificial intelligence(AI)technology and the proliferation of medical digital information,AI has demonstrated promising sensitivity and accuracy in assisting precise detection,treatment decision-making,and prognosis assessment of *** has become a unique opportunity to enhance comprehen-sive clinical management of ESCC in the era of precision *** review examines how AI is applied to the diagnosis,treatment,and prognosis assessment of ESCC in the era of precision oncology,and analyzes the challenges and potential opportunities that AI faces in clinical *** insights into future prospects,it is hoped that this review will contribute to the real-world application of AI in future clinical settings,ultimately alleviating the disease burden caused by ESCC.

关键词： Esophageal squamous cell carcinoma Artificial intelligence Deep learning Machine learning Precision tumor therapy

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Enhancing the Photosensitivity of Hypocrellin A by Perylene Diimide Metallacage‑Based Host–Guest Complexation for Photodynamic Therapy

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Nano-Micro Letters 2024年第11期16卷 71-87页

作者： Rongrong Li Tianfeng Yang Xiuhong Peng Qian Feng Yali Hou Jiao Zhu Dake Chu Xianglong Duan Yanming Zhang Mingming Zhang State Key Laboratory for Mechanical Behavior of Materials Shaanxi International Research Center for Soft MatterSchool of Materials Science and EngineeringXi’an Jiaotong UniversityXi’an 710049People’s Republic of China School of Pharmacy Health Science CenterXi’an Jiaotong UniversityXi’an 710061People’s Republic of China department of Rehabilitation Medicine Shaanxi Provincial People’s HospitalXi’an 710068ShaanxiPeople’s Republic of China department of Gastroenterology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061People’s Republic of China

The development of supramolecular hosts which can efficiently encapsulate photosensitizers to improve the photodynamic efficacy holds great promise for cancer ***,we report two perylene diimide-based metallacages that can form stable host–guest complexes with planar conjugated molecules including polycyclic aromatic hydrocarbons and photosensitizers(hypocrellin A).Such host–guest complexation not only prevents the aggregation of photosensitizers in aqueous environments,but also offers fluorescence resonance energy transfer(FRET)from the metallacage to the photosensitizers to further improve the singlet oxygen generation(Φ_(Δ)=0.66).The complexes are further assembled with amphiphilic polymers,forming nanoparticles with improved stability for anticancer *** in vitro and in vivo studies indicate that the nanoparticles display excellent anticancer activities upon light irradiation,showing great potential for cancer photodynamic *** study provides a straightforward and effective approach for enhancing the photosensitivity of conventional photosensitizers via host–guest complexation-based FRET,which will open a new avenue for host–guest chemistry-based supramolecular theranostics.

关键词： Metallacages Host-guest interactions Fluorescence resonance energy transfer Singlet oxygen Photodynamic therapy

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Climate change vulnerability assessment in the new urban planning process in Tanzania

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Regional Sustainability 2024年第3期5卷 1-11页

作者： Issa NYASHILU Robert KIUNSI Alphonce KYESSI Vice President’s Office Government CityDodoma2502Tanzania department of Environmental engineering and Technology Ardhi UniversityDar es Salaam35176Tanzania Institute of Human Settlements Studies Ardhi UniversityDar es Salaam35176Tanzania

Climate change vulnerability assessment is an essential tool for identifying regions that are most susceptible to the impacts of climate change and designing effective adaptation actions that can reduce vulnerability and enhance long-term resilience of these *** study explored a framework for climate change vulnerability assessment in the new urban planning process in Jangwani Ward,***,taking flood as an example,this study highlighted the steps and methods for climate change vulnerability assessment in the new urban planning *** the study area,95 households were selected and interviewed through purposeful ***,10 respondents(4 females and 6 males)were interviewed for Focus Group Discussion(FGD),and 3 respondents(1 female and 2 males)were selected for Key Informant Interviews(KII)at the Ministry of Lands,Housing and Human Settlements *** study indicated that climate change vulnerability assessment framework involves the assessment of climatic hazards,risk elements,and adaptive capacity,and the determination of vulnerability *** average hazard risk rating of flood was *** and livelihood activities and physical infrastructures both had the average risk element rating of 3.0,and ecosystems had the average risk element rating of *** capacity ratings of knowledge,technology,economy or finance,and institution were 1.6,1.9,1.4,and 2.2,*** vulnerability levels of socioeconomic and livelihood activities and physical infrastructure were very high(4.0).Ecosystems had a high vulnerability level(3.8)to *** very high vulnerability level of socioeconomic and livelihood activities was driven by high exposure and sensitivity to risk elements and low adaptive *** study recommends adoption of the new urban planning process including preparation,planning,implementation,and monitoring-evaluation-review phases that integrates climate change vulnerability assessment in

关键词： Climate change Vulnerability level Climatic hazard Risk elements Adaptive capacity New urban planning process

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New acoustic system for continuous measurement of river discharge and water temperature

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Water Science and engineering 2010年第1期3卷 47-55页

作者： Kiyosi KAWANISI Arata KANEKO Shinya NIGO Mohammad SOLTANIASL Mahmoud F. MAGHREBI Graduate School of engineering Hiroshima University Ministry of Land InfrastructureTransport and Tourism(Kitaku) Civil engineering department Ferdowsi University of Mashhad

In many cases, river discharge is indirectly estimated from water level or streamflow velocity near the water surface. However, these methods have limited applicability. In this study, an innovative system, the fluvial acoustic tomography system （FATS）, was used for continuous discharge measurement. Transducers with a central frequency of 30 kHz were installed diagonally across the river. The system＇s significant functions include accurate measurement of the travel time of the transmission signal using a GPS clock and the attainment of a high signal-to-noise ratio as a result of modulation of the signal by the 10th order M-sequence. In addition, FATS is small and lightweight, and its power consumption is low. Operating in unsteady streamflow, FATS successfully measured the cross-sectional average velocity. The agreement between FATS and acoustic Doppler current profilers （ADCPs） on water discharge was satisfactory. Moreover, the temporal variation of the cross-sectional average temperature deduced from the sound speed of FATS was similar to that measured by a temperature sensor near the bank.

关键词： streamflow fluvial acoustic tomography cross-sectional average velocity unsteadyflow water temperature

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Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1359-1388页

作者： Qian Zhou Yu Meng Daishi Li Lei Yao Jiayuan Le Yihuang Liu Yuming Sun Furong Zeng Xiang Chen Guangtong Deng department of Dermatology Xiangya HospitalCentral South University87 Xiangya RoadChangsha 410008 Hunan ProvinceChina National engineering Research Center of Personalized Diagnostic and Therapeutic Technology 87 Xiangya RoadChangsha 410008 Hunan ProvinceChina Furong Laboratory 87 Xiangya RoadChangsha 410008 Hunan ProvinceChina Hunan Key Laboratory of Skin Cancer and Psoriasis Hunan Engineering Research Center of Skin Health and DiseaseXiangya HospitalCentral South University87 Xiangya RoadChangsha 410008 Hunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya Hospital87 Xiangya RoadChangsha 410008 Hunan ProvinceChina department of General Surgery Xiangya HospitalCentral South University87 Xiangya RoadChangsha 410008 Hunan ProvinceChina department of Plastic and Cosmetic Surgery Xiangya HospitalCentral South University87 Xiangya RoadChangsha 410008 Hunan ProvinceChina department of Oncology Xiangya HospitalCentral South University87Xiangya RoadChangsha 410008Hunan ProvinceChina

Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal accumulation of iron-dependent membranelocalized lipid *** acts as an innate tumor suppressor mechanism and participates in the biological processes of ***,mesenchymal and dedifferentiated cancer cells,which are usually resistant to apoptosis and traditional therapies,are exquisitely vulnerable to ferroptosis,further underscoring its potential as a treatment approach for cancers,especially for refractory ***,the impact of ferroptosis on cancer extends beyond its direct cytotoxic effect on tumor *** induction not only inhibits cancer but also promotes cancer development due to its potential negative impact on anticancer ***,a comprehensive understanding of the role of ferroptosis in cancer is crucial for the successful translation of ferroptosis therapy from the laboratory to clinical *** this review,we provide an overview of the recent advancements in understanding ferroptosis in cancer,covering molecular mechanisms,biological functions,regulatory pathways,and interactions with the tumor *** also summarize the potential applications of ferroptosis induction in immunotherapy,radiotherapy,and systemic therapy,as well as ferroptosis inhibition for cancer treatment in various *** finally discuss ferroptosis markers,the current challenges and future directions of ferroptosis in the treatment of cancer.

关键词： cancer mechanisms treatment

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Long cycle-life aqueous Zn battery enabled by facile carbon nanotube coating on Cu current collector

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Carbon Energy 2024年第6期6卷 151-164页

作者： Beom-Keun Cho Sung-Ho Huh So Hee Kim Seungho Yu Jong-Seong Bae Jung-Keun Yoo Seung-Ho Yu department of Chemical and Biological engineering Korea UniversitySeoulRepublic of Korea Advanced Analysis Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea Energy Storage Research Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea KIST School Division of Energy and Environment TechnologyKorea University of Science and TechnologySeoulRepublic of Korea Busan Center Korea Basic Science Institute(KBSI)BusanRepublic of Korea Carbon Composites department Composites Research DivisionKorea Institute of Materials Science(KIMS)ChangwonRepublic of Korea

As an alternative to Li-ion batteries,aqueous Zn batteries have gained attention due to the abundance of Zn metal,low reduction potential(-0.76 V *** hydrogen electrode),and high theoretical capacity(820 mAh g^(-1))of multivalent Zn2+***,the growth of Zn dendrites and the formation of irreversible surface reaction byproducts pose challenges for ensuring a long battery lifespan and ***,the Cu foil coated with a single-walled carbon nanotube(SWCNT)layer using a facile doctor blade casting method is *** SWCNT-coated Cu foil demonstrates a significantly longer battery lifespan compared to the bare Cu in the half-cell *** operando optical microscopy imaging,we are able to provide intuitive evidence that Zn deposition occurs between the carbon nanotube(CNT)coating and Cu substrate,in agreement with the computational ***,with various imaging techniques,the flat morphology and homogeneous distribution of Zn beneath the SWCNT layer are *** addition,the full-cell using CNT-coated Cu exhibits a long cycle life compared to the control group,thereby demonstrating improved electrochemical performance with limited Zn for the cycling process.

关键词： aqueous Zn battery carbon nanotube operando imaging surface coating

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