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Understanding the eff ect of recreational drug use on bone health and musculoskeletal disease in the establishment of pain regimens

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World Journal of Emergency medicine 2024年第5期15卷 356-364页

作者： Ariella Gartenberg Alexander Petrie Winston Yen Woojn Cho Emergency medicine Department Montefi ore Medical Center and Jacobi Medical CenterNew York 10461USA Emergency medicine Department Jacobi Medical Center and North Central BronxNew York 10461USA touro college of osteopathic medicine Touro UniversityNew York 10027USA

BACKGROUND:The widespread use of recreational drugs has raised concerns regarding their eff ects on various organ *** use of cannabis and opioids in chronic pain management increases their prevalence among patients with musculoskeletal conditions whose bone health may already be *** article aims to review the pathophysiology and toxic eff ects of recreational drug use on musculoskeletal health to establish appropriate pain regimens for patients with substance ***:Medical literature published from 1970 until 2022 was identifi ed utilizing MEDLINE/PubMed and the Cochrane *** addition to the databases,references were obtained through the use of reference lists of published articles identifi ed by the aforementioned *** initial search terms included opioids,inhalants,hallucinogens,cannabis,stimulants,and bone *** were no methodological limitations in relation to the initial acquisition and analysis of ***:A total of 55 research articles were included in this ***,stimulants,opioids,and inhalants impact bone maintenance,specifically osteoblast and osteoclast activity,as well as impede hormone *** substances inhibit bone remodeling and development,manifesting as lower bone mineral density and increased fracture risk in chronic ***:Although the current literature suggests a deleterious effect of recreational drugs on bone health and musculoskeletal disease,further research is warranted to evaluate the clinical effects of long-term substance *** evaluation of such effects will aid in establishing appropriate pain regimens,as well as appropriate screening and treatment plans for recreational drug users.

关键词： Musculoskeletal disorders Bone health Cannabis Opioids Stimulants

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The Impact of Psychosocial Influences on Chronic Wound Healing

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Open Journal of Medical Psychology 2024年第3期13卷 39-57页

作者： Kelly Frasier Vivian Li Sara Christoforides Kathleen Daly Alexandra Loperfito Karina Stech Milena Dragovic Nuvance Health/Vassar Brothers Medical Center Poughkeepsie NY USA Lake Erie college of osteopathic medicine New York NY USA Medical college of Georgia Augusta University Augusta GA USA Edward Via college of osteopathic medicine Blacksburg VA USA Lewis Katz School of medicine Temple University Philadelphia PA USA college of osteopathic medicine California Health Sciences University Clovis CA USA

This comprehensive review explores the intricate dynamics between psychosocial factors and chronic wound healing processes, specifically focusing on prevalent conditions such as pressure ulcers, diabetic foot ulcers, and venous leg ulcers. By examining the roles of psychiatric conditions, including depression, anxiety, and post-traumatic stress disorder (PTSD), this paper illuminates how these factors intricately influence wound healing dynamics, including mechanisms of pain perception and inflammatory responses. Furthermore, we evaluate the effectiveness of integrated biopsychosocial interventions, which encompass a holistic approach to wound care, thereby enhancing healing outcomes for dermatology patients. Future studies should focus on investigating the specific psychosocial determinants that significantly influence wound healing, exploring novel therapeutic strategies, and implementing personalized interventions to meet the unique needs of each patient. Such endeavors hold promise in advancing the fields of psychodermatology and wound management, fostering a deeper understanding and application of psychosocial considerations in dermatological care.

关键词： Psychosocial Factors Chronic Wound Healing Biopsychosocial Interventions Psychiatric Conditions Dermatology Patients

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Psychiatric Sequelae of Chronic Pruritic Dermatoses

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Open Journal of Medical Psychology 2024年第2期13卷 25-38页

作者： Kelly Frasier Vivian Li Kathleen Click Christina Dudzik Michelle Sobotka Evadne Rodriguez Karina Stech Nuvance Health/Vassar Brothers Medical Center Poughkeepsie NY USA School of osteopathic medicine Kansas City University Kansas City MO USA touro college of osteopathic medicine Middleton Campus Middletown NY USA Abrazo Health Network Goodyear AZ USA School of medicine University of Missouri-Columbia Columbia MO USA Lewis Katz School of medicine at Temple university Philadelphia PA USA

This comprehensive review investigates the significant psychological impact and profound psychological comorbidities found in individuals suffering from chronic pruritic dermatoses, including atopic dermatitis, chronic urticaria, and prurigo nodularis. Highlighting the complex, reciprocal relationship between pruritus and psychiatric conditions such as depression, anxiety, and sleep disturbances, this paper elucidates the comprehensive impact of dermatological disorders on the skin in addition to the far-reaching effects on an individual’s psychological well-being. By evaluating the efficacy of integrated psychodermatological interventions, including cognitive behavioral therapy, mindfulness practices, pharmacological treatments, and innovative telepsychiatry and digital health solutions, this review aims to lay the foundation for a more holistic approach to treatment of concurrent dermatological and psychiatric conditions. Future research endeavors should delve deeper into the mechanistic foundation of the pruritus-psychiatry interface, the refinement of tailored treatment strategies, and the evaluation of long-term patient outcomes. In doing so, this review seeks to contribute to the optimization of patient care and well-being, underscoring the pivotal role of addressing both dermatological and psychological needs in achieving comprehensive health outcomes.

关键词： Psychodermatology Chronic Pruritic Dermatoses Psychological Comorbidities Integrated Interventions Pruritus-Psychiatry Interface

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Epidemiologic investigation of pediatric distal humerus fractures: An American insurance claims database study

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World Journal of Orthopedics 2024年第1期15卷 52-60页

作者： Kyle Jay Klahs Jake E Dertinger Grant T Mello Kevin Thapa Alexis B Sandler E'Stephan J Jesus Garcia Nata Parnes Department of Orthopaedic Surgery Texas Tech University Health Sciences-El PasoEl PasoTX 79905United States Medical School California Health Sciences University College of Osteopathic MedicineClovisCA 93611United States Undergraduate School Binghampton UniversityVestalNY 13902United States Department of Orthopaedic Surgery William Beaumont Army Medical CenterFort BlissTX 79918United States Department of Orthopaedic Surgery Carthage Area HospitalCarthageNY 13619United States

BACKGROUND Distal humerus elbow fractures are one of the most common traumatic fractures seen in pediatric patients and present as three main types:Supracondylar(SC),lateral condyle(LC),and medial epicondyle(ME)*** To evaluate the epidemiology of pediatric distal humerus fractures(SC,LC,and ME)from an American insurance claims *** A retrospective review was performed on patients 17 years and younger with the ICD 9 and 10 codes for SC,LC and ME fractures based on the IBM Truven MarketScan®Commercial and IBM Truven MarketScan Medicare Supplemental *** from 2015 to 2020 were queried for treatments,patient age,sex,length of hospitalization,and *** A total of 1133 SC,154 LC,and 124 ME fractures were *** fractures had the highest percentage of operation at 83%,followed by LC(78%)and ME fractures(41%).Male patients were,on average,older than female patients for both SC and ME *** In the insurance claims databases used,SC fractures were the most reported,followed by LC fractures,and finally ME *** was identified to be a factor for how a pediatric distal humerus fractures,with patients with SC and LC fractures being younger than those with ME *** peak age per injury per sex was similar to reported historic central tendencies,despite reported trends for younger physiologic development.

关键词： Supracondylar humerus fracture Lateral condyle fracture Medial epicondyle fracture Pediatric elbow Truven Epidemiology

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Coronary artery disease presenting as intractable hiccups:an unclear mechanism

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Journal of Geriatric Cardiology 2021年第5期18卷 398-399页

作者： Alor Sahoo Sarabjeet Singh Central Cardiology Medical Center BakersfieldCAUSA Central Cardiology Medical Center Cedars-SinaiCollege of Osteopathic MedicineTouro University CaliforniaVallejoCAUSA

A 66yearold gentleman presented for a cardiovascular evaluation secondary to chest discomfort,right knee pain,and intractable *** patient also had type 2 diabetes mellitus,hypercholesterolemia,aortic atherosclerosis,and ascending aortic *** family history was also significant for premature coronary artery disease in the *** patient had been compliant with his medical therapy,which included subcutaneous 200 units/mL insulin degludec,18 mg/3 mL subcutaneous liraglutide,daily oral 500 mg metformin hydrochloride,daily oral 100 mg sitagliptin,daily oral 12.5 mg zolpidem,daily oral 5 mg tadalafil,and 20 mg tablet rosuvastatin daily.

关键词： artery cardiovascular intractable

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Effectiveness of seatbelts in mitigating traumatic brain injury severity

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World Journal of Emergency medicine 2021年第1期12卷 68-72页

作者： Latha Ganti Aakash NBodhit Yasamin Daneshvar Kelsey Hatchitt Sudeep Kuchibhotla Christa Pulvino Sarah WAyala Keith RPeters Emergency medicine and Neurology University of Central Florida College of MedicineOrlando 32827USA Department of Neurology Saint Louis UniversitySaint Louis 63103USA New York college of Podiatric medicine New York 10035USA George Washington university Washington DC 20052USA Texas Heart Institute Houston 77030USA Department of Emergency medicine University of CincinnatiCincinnati 45221USA touro college of osteopathic medicine Vallejo 94592USA Department of Radiology University of FloridaGainesville 32610USA

INTRODUCTION Over the past few decades,traumatic brain injuries(TBIs)have become one of the leading causes of death and the leading cause of injury-related death in the USA.[1,2]It is estimated that 1.70 million people are subject to TBIs each year.[2]Males are more likely to sustain TBIs(59%);the most common age groups are 0–5 years,15–19 years,and>65 years.[2]Approximately 1.36 million people present to the emergency department(ED),275,000 are admitted to the hospital,and 52,000 people die from TBIs.[2]The leading causes of TBIs are falling(35.2%),motor vehicle collisions(MVCs,17.3%),struck by/against an object(16.5%),and assault(10.0%).[2]These statistics combine to make TBIs the leading cause of injury-related death in the USA at 30.5%.[2]It has been estimated that,with specifi c guidelines from the Brain Trauma Foundation,up to 50.0%of the 52,000 TBIrelated deaths may be prevented.[3]

关键词： admitted injuries traumatic

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Scabies Surrepticius (Presenting as Crusted-Norwegian-Scabies, Scalp Scabies, and Scabies Incognito) in an Immunocompromised Patient: A Challenging Condition to Diagnose and Treat

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International Journal of Dermatology and Venereology 2020年第3期3卷 184-185页

作者： Philip R.Cohen San Diego Family Dermatology National CityCAUSA touro university california college of osteopathic medicine VallejoCAUSA

Dear Editor:I read with interest the excellent report by Zhang et al.1 of a 55-year-old woman with Norwegian scabies(which is also referred to as crusted scabies)that masqueraded as scalp seborrheic dermatitis for 5 months until the correct diagnosis was *** authors attributed her immunosuppressed state-which accounted not only for the crusted scabies but also its location on her scalp in addition to other body areas-to a chronic hepatitis C *** mite infestation also had a component of scabies incognito from the application of high-potency topical corticosteroids(0.05%fluticasone propionate cream and 0.1%halcinonide solution)for 5 months.

关键词： abies attributed diagnosis

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Advances in endovascular aneurysm management: coiling and adjunctive devices

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Stroke & Vascular Neurology 2020年第1期5卷 14-21页

作者： Jessica K Campos Brian V Lien Alice S Wang Li-Mei Lin Department of Neurological Surgery University of California Irvine Medical CenterOrangeCaliforniaUSA college of osteopathic medicine of the Pacific Western University of Health SciencesPomonaCaliforniaUSA Carondelet Neurological Institute St.Joseph's HospitalCarondelet Health NetworkTucsonAZUnited States

Endovascular coil embolisation continues to evolve and remains a valid modality in managing ruptured and unruptured cerebral *** advances in coil properties,adjunctive devices and interventional techniques continue to improve long-term aneurysm occlusion *** review elaborates on the latest advances in next-generation endovascular coils and adjunctive coiling techniques for treating cerebral aneurysms.

关键词： aneurysm cerebral endovascular

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Emerging wearable technology applications in gastroenterology:A review of the literature

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World Journal of Gastroenterology 2021年第12期27卷 1149-1160页

作者： Kimberly PL Chong Benjamin KP Woo college of osteopathic medicine Western University of Health SciencesPomonaCA 91766United States Department of Psychiatry and Biobehavioral Sciences Olive View-University of California Los Angeles Medical CenterSylmarCA 91342United States

The field of gastroenterology has recently seen a surge in wearable technology to monitor physical activity,sleep quality,pain,and even gut *** past decade has seen the emergence of wearable devices including Fitbit,Apple Watch,AbStats,and ingestible *** this review,we discuss current and future devices designed to measure sweat biomarkers,steps taken,sleep efficiency,gastric electrical activity,stomach pH,and intestinal *** also summarize several clinical studies to better understand wearable devices so that we may assess their potential benefit in improving healthcare while also weighing the challenges that must be addressed.

关键词： Wearable technology Wearables Ingestibles Smartphone Remote patient monitoring Gastroenterology

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Multimodal management of giant cerebral aneurysms: review of literature and case presentation

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Stroke & Vascular Neurology 2020年第1期5卷 22-28页

作者： Jessica K Campos Benjamin Z Ball Barry Cheaney II Alexander J Sweidan Bima J Hasjim Frank P K Hsu Alice S Wang Li-Mei Lin Department of Neurosurgery University of California Irvine Medical CenterOrangeCaliforniaUSA Oregon Health&Science university School of MedicinePortlandOregonUSA Department of Neurology University of California Irvine Medical CenterOrangeCaliforniaUSA Western university of Health Sciences College of Osteopathic Medicine of the PacificPomonaCaliforniaUSA Carondelet Neurological Institute St Joseph’s HospitalCarondelet Health NetworkTucsonArizonaUSA

The pathophysiology of giant cerebral aneurysms renders them difficult to *** in technology have attempted to address any shortcomings associated with open surgery or endovascular *** the introduction of the flow diversion technique,the endovascular approach with flow diversion has become the first-line modality chosen to treat giant aneurysms.A subset of these giant aneurysms may persistent despite any treatment *** the best option for these recurrent and/or persistent giant aneurysms is to employ a multimodal approach-both surgical and endovascular-rather than any single technique to provide a curative result with favourable patient *** paper provides a review of the histopathology and treatment options for giant cerebral ***,an illustrative case is presented to highlight the unique challenges of a curative solution for giant cerebral aneurysms that persist despite initial treatment.

关键词： aneurysm cerebral giant

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