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Spatial distribution of shallow landslides caused by Typhoon Lekima in 2019 in Zhejiang Province, China

Journal of Mountain Science 2024年第5期21卷 1564-1580页

作者： CUI Yulong YANG Liu XU Chong ZHENG Jun School of Civil Engineering and Architecture Anhui University of Science and TechnologyHuainan 232001China National Institute of Natural Hazards Ministry of Emergency Management of ChinaBeijing 100085China department of Civil Engineering Zhejiang UniversityHangzhou 310058China

In recent years, the coastal region of Southeast China has witnessed a significant increase in the frequency and intensity of extreme rainfall events associated with landfalling typhoons. The hilly and mountainous terrain of this area, combined with rapid rainfall accumulation, has led to a surge in flash floods and severe geological hazards. On August 10, 2019, Typhoon Lekima made landfall in Zhejiang Province, China, and its torrential rainfall triggered extensive landslides, resulting in substantial damage and economic losses. Utilizing high-resolution satellite images, we compiled a landslide inventory of the affected area, which comprises a total of 2,774 rainfallinduced landslides over an area of 2965 km2. The majority of these landslides were small to mediumsized and exhibited elongated, clustered patterns. Some landslides displayed characteristics of high-level initiation, obstructing or partially blocking rivers, leading to the formation of debris dams. We used the inventory to analyze the distribution pattern of the landslides and their relationship with topographical, geological, and hydrological factors. The results showed that landslide abundance was closely related to elevation, slope angle, faults, and road density. The landslides were predominantly located in hilly and low mountainous areas, with elevations ranging from 150 to 300 m, slopes of 20 to 30 degrees, and a NE-SE aspect. Notably, we observed the highest Landslide Number Density(LND) and Landslide Area Percentage(LAP) in the rhyolite region. Landslides were concentrated within approximately 4 km on either side of fault zones, with their size and frequency negatively correlated with distances to faults, roads, and river systems. Furthermore, under the influence of typhoons, regions with denser vegetation cover exhibited higher landslide density, reaching maximum values in shrubland areas. In areas experiencing significantly increased concentrated rainfall, landslide density also showed a corr

关键词： Typhoon rainfall Landslide characteristics Spatial distribution Southeast coastal region

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Effects of the urban landscape on heatwave-mortality associations in Hong Kong: comparison of different heatwave definitions

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Frontiers of Environmental Science & Engineering 2024年第1期18卷 145-156页

作者： Jinglu Song Yi Lu Thomas Fischer Kejia Hu department of Urban Planning and Design Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China department of Architecture and Civil Engineering City University of Hong KongKowloon TongHong Kong 999077China Environmental Assessment and management Research Centre School of Environmental SciencesUniversity of LiverpoolLiverpool L35TRUK Research Unit for Environmental Sciences and management Faculty of Natural and Agricultural SciencesNorth West UniversityPotchefstroom 31750South Africa Institute of Big Data in Health Science School of Public HealthZhejiang UniversityZijingang CampusHangzhou 310058China

Despite increased attention given to potential modifiers of temperature-mortality associations, evidence for variations between different urban landscape characteristics remains limited. It is in this context that in this paper effect modifications of multiple urban landscape characteristics are explored under different heatwave definitions for different age groups and gender in Hong Kong, China. Daily meteorological data and heatwave-related mortality counts from 2008 to 2017 were collected from the Hong Kong Census and Statistics department, China. A case-only design was adopted, combined with logistic regression models to examine the modification effects of five urban landscape characteristics under six heatwave definitions. Stratified analyses were conducted to investigate age- and gender-specific effect modifications. It is found that individuals living in greener areas experienced lower levels of mortality during or immediately after heatwaves. In contrast, a higher building density and nighttime land surface temperature (LST) were associated with a higher heatwave-related mortality risk. Pronounced effect modifications of these urban landscape characteristics were observed under hotter and longer heatwaves, and in older adults (age ≥ 65 years) and males. The findings provide a scientific basis for policymakers and practitioners when considering measures for coping with hotter, longer, and more frequent heatwaves in the context of global climate change.

关键词： Urban landscape Heatwave Mortality Effect modification Intra-urban differences Health risk reduction

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Applying Machine Learning Approach to Explore Childhood Circumstances and Self-Rated Health in Old Age-China and the US,2020-2021

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China CDC weekly 2024年第11期6卷 213-218,I0008-I0013页

作者： Shutong Huo Derek Feng Thomas M.Gill Xi Chen department of Health Society&BehaviorPublic HealthUniversity of CaliforniaIrvineCAUSA department of Statistics and Data Science Yale UniversityNew HavenCTUS department of Internal Medicine Yale School of MedicineNew HavenCTUS department of Health Policy and management Yale School of Public HealthNew HavenCTUS department of Economics Yale UniversityNew HavenCTUS.

Introduction:Childhood circumstances impact senior health,prompting the introduction of machine learning methods to assess their individual and collective contributions to senior ***:Using health and retirement study(HRS)and China Health and Retirement Longitudinal Study(CHARLS),we analyzed 2,434 American and 5,612 Chinese participants aged 60 and *** inference trees and forests were employed to estimate the influence of childhood circumstances on self-rated health(SRH).Results:The conventional method estimated higher inequality of opportunity(IOP)values in both China(0.039,accounting for 22.67%of the total Gini coefficient 0.172)and the US(0.067,accounting for 35.08%of the total Gini coefficient 0.191).In contrast,the conditional inference tree yielded lower estimates(China:0.022,accounting for 12.79%of 0.172;US:0.044,accounting for 23.04%of 0.191),as did the forest(China:0.035,accounting for 20.35%of 0.172;US:0.054,accounting for 28.27%of 0.191).Childhood health,financial status,and regional differences were key determinants of senior *** conditional inference forest consistently outperformed others in predictive accuracy,as demonstrated by lower out-of-sample mean squared error(MSE).Discussion:The findings emphasize the need for early-life interventions to promote health equity in aging *** learning showcases the potential in identifying contributing factors.

关键词： collective inequality estimates

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Sorafenib sensitization in tumor therapy by iron overload and AMPK activation

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Nano Research 2024年第7期17卷 6386-6399页

作者： Jun Zhu Shoujie Zhao Yejing Zhu Shouzheng Ma Tenghui Han Fenghua Xu Huichen Li Bo Wang Zhixiong Guo Da Chen Yongquan Qu Zhimin Tian Junlong Zhao Lei Liu State Key Laboratory of Holistic Integrative management of Gastrointestinal Cancers National Clinical Research Center for Digestive DiseasesXijing HospitalFourth Military Medical UniversityXi’an 710032China department of General Surgery The Southern Theater Air Force HospitalGuangzhou 510602China department of General Surgery Tangdu HospitalFourth Military Medical UniversityXi’an 710038China department of Thoracic Surgery Tangdu HospitalFourth Military Medical UniversityXi’an 710038China department of Neurology Airborne Army HospitalWuhan 430012China Key Laboratory of Modern Teaching Technology(Ministry of Education) Shaanxi Normal UniversityXi’an 710062China State Key Laboratory of Holistic Integrative management of Gastrointestinal Cancers Department of Biochemistry and Molecular BiologySchool of Basic MedicineFourth Military Medical UniversityXi’an 710032China Key Laboratory of Special Functional and Smart Polymer Materials of Ministry of Industry and Information Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China State Key Laboratory of Holistic Integrative management of Gastrointestinal Cancers Department of Medical Genetics and Developmental BiologyFourth Military Medical UniversityXi’an 710032China department of Pediatrics Tangdu HospitalFourth Military Medical UniversityXi’an 710000China

Sorafenib,as a first-line drug for advanced hepatocellular carcinoma(HCC),could trigger ferroptosis by inhibiting cystine/glutamate ***,low-level intracellular iron and insufficient activation of adenosine monophosphate(AMP)-activated protein kinase(AMPK)confer impaired response to *** this study,a unique sorafenib nanocomposite dexterously modified with Fe-Material of Institut Lavoisier(sora@Fe-MIL)was synthesized to escalate intracellular iron level and activate AMPK,further potentiating the ferroptotic effect of ***,this strategic deployment of sora@Fe-MIL triggered an extensive demise of cancer cells,while manifesting negligible deleterious impact on normal *** prominent ferroptosis biomarkers,glutathione peroxidase 4(GPX4)and solute carrier family 7 member 11(SLC7A11),underwent pronounced downregulation,underscoring the efficacy of this strategy in inducing ***,the bioactivity of AMPK was considerably elevated,and its downstream targets were conspicuously inhibited by the treatment with sora@*** orthotopic HCC animal models,we observed a substantial suppression of primary in situ tumor growth,and ribonucleic acid(RNA)sequencing elucidated an elevated degree of ferroptosis and AMPK activation with the treatment of sora@*** conclusion,we proposed that the meticulously designed strategy for secure and efficacious iron release and AMPK activation could significantly potentiate the ferroptotic impact of sorafenib,thus resuscitating its therapeutic response in HCC patients.

关键词： anti-tumor ferroptosis Fe-Material of Institut Lavoisier(Fe-MIL) sorafenib adenosine monophosphate(AMP)-activated protein kinase(AMPK)

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Identifying the effective combination of acupuncture and traditional Chinese medicinal herbs for postmenopausal osteoporosis therapy through studies of their molecular regulation of bone homeostasis

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Journal of Traditional Chinese Medicine 2024年第1期44卷 212-219页

作者： REN Ping WANG Quanwu BAI Wei SUN Miao LIU Zheling GAO Ming WANG Liang PENG Bo XU Liguang department of Health management the Third Affiliated Clinical Hospital of Changchun University of Chinese MedicineChangchun 130117China department of Dirty Tuina the affiliated Hospital to Changchun University of Chinese MedicineChangchun 130117China department of Acupuncture the affiliated Hospital to Changchun University of Chinese MedicineChangchun 130117China department of Rehabilitation Medicine the 924th Hospital of the PLA Joint Logistic Support ForceFoshan 528226China department of College of Acupuncture and Massage Changchun University of Chinese MedicineChangchun 130117China

Worldwide,as the population age,osteoporosis is becoming increasingly common,and osteoporotic fractures have a significant economic *** women are the most susceptible to developing osteoporosis and the most critical time to prevent it is during the perimenopausal and early menopausal *** this regard,we hypothesize rational combination of acupuncture and Traditional Chinese Medicine(TCM)in the form of herbal extract could prevent osteoporosis in *** deficiency during menopause causes low-level inflammation that stimulates the formation of osteoclasts,the boneresorbing cells,and simultaneously inhibits the viability and function of osteoblasts,the bone-forming *** most potent inflammatory cytokine in skeletal homeostasis is the receptor activator of nuclear factor kappa B ligand(RANKL)that stimulates osteoclast ***,the canonical Wnt pathway is essential for osteoblastogenesis and bone formation,and estrogen deficiency leads to diminished functioning of this *** and acupuncture could target the RANKL and the Wnt pathway in favorable ways to prevent the accelerated bone loss experienced during the early menopausal stage and promote the gain in bone mass in postmenopausal *** this review,we propose a rational combination of specific TCM and acupuncture targeting those signaling molecules/pathways by the drugs that are in clinical use for the treatment of postmenopausal *** rational approach revealed that Danshen(Radix Salviae Miltiorrhizae)could exert a synergistic effect with *** then propose a translational path for developing the putative combination in women with postmenopausal osteoporosis to curtail the risk of osteoporotic fractures.

关键词： medicine traditional osteogenic anti-resorptive review

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Reducing children’s exposure to di(2-ethylhexyl)phthalate in homes and kindergartens in China:Impact on lifetime cancer risks and burden of disease

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Building Simulation 2024年第3期17卷 431-440页

作者： Dongsheng Tao Wen Sun Donghui Mo Yonghui Lin Wei Lv Daniel Mmereki Yousheng Xu Yanghui Ye Yuanjun Tang Chao Ye Cong Dong Zhongming Bu Zhejiang Ecowell Energy management Technology Co. LtdHangzhouChina department of Energy and Environmental System Engineering Zhejiang University of Science and TechnologyHangzhouChina Faculty of Health Sciences School of Clinical MedicineUniversity of the WitwatersrandParktown2193JohannesburgSouth Africa

Exposure to di(2-ethylhexyl)phthalate(DEHP)in the indoor environment has been linked with significant health risks for Chinese ***-phase DEHP concentrations in Chinese residences and kindergartens were estimated using a mass balance model based on the current baseline condition and control strategies(i.e.,increasing ventilation rate,reducing area of sources,using mechanical ventilation systems,and using portable air cleaners).The health benefits of each control strategy were quantified as the reduction in lifetime cancer risks(LCR)and burden of disease(BoD).In the current situation,the mean LCR and disability-adjusted life years(DALY)number attributable to indoor DEHP exposure for Chinese children were around 6.0×10^(−6) and 155 thousand,*** mean LCR and DALY might be reduced by 25%-54%and 16%-40%,respectively,by increasing air exchange rates by 100%,reducing the use of source materials by two-thirds or deploying commercial air cleaners in naturally ventilated ***,avoidable DALYs could result in a reduction of mean economic losses of 2.2-5.3 billion *** ventilation systems with filtration units may not be helpful for reducing children’s health ***-specific and tailor-made control measures are critical in lowering indoor exposure to DEHP to promote sustainable buildings and children’s health in China.

关键词： indoor air di(2-ethylhexyl)phthalate children exposure control strategies health benefits

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Effects of low molecular weight polysaccharide from Sargassum thunbergii against palmitic acid-induced intracellular lipid accumulation in 3T3-L1 adipocyte and HepG2 cells

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Food Science and Human Wellness 2024年第4期13卷 2244-2252页

作者： Hyo-Geun Lee D.P.Nagahawatta M.J.M.S.Kurera Kyung-Mo Song Yun-Sang Choi You-Jin Jeon Min-Cheol Kang department of Marine Life Sciences Jeju National UniversityJeju 63243Republic of Korea department of Biotechnology Faculty of Agriculture and Plantation ManagementWayamba University of Sri LankaMakanduraGonawila(NWP)60170Sri Lanka Research Group of Food Processing Korea Food Research Institute245Wanju 55365Republic of Korea

Low molecular weight polysaccharides can be isolated from Sargassum thunbergii(LMPST)and in vitro experiments were conducted to evaluate the inhibitory effects on *** natures of LMPST were attained from *** and appraised their LMPST on palmitic acid(PA)induced lipid accretion in Hep G2,and 3T3-L1 *** treatment lessened lipid deposition and intracellular free fatty acid and triglyceride intensities in PA-treated above mentioned *** mechanistic study publicized that LMPST2 significantly suppressed adipogenesis and stimulated the PA-treated 3T3-L1 cells occupied in the lipolysis ***,in PA-treated Hep G2 cells,the free fatty acid oxidation was significantly increased by *** these constructive properties of LMPST2 from ***,is a potential candidate for diminishing the intracellular lipids,and for a therapeutic agent in those conditions.

关键词： Sargassum thunbergii Low molecular weight polysaccharide Lipid accumulation Obesity Liver steatosis

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Relationships among Sedentary Time,Electronic Product Addiction,and Depression in Adolescents during the COVID-19 Epidemic:A Cross-Lagged Study

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International Journal of Mental Health Promotion 2024年第3期26卷 221-228页

作者： Feng Sheng Chen Kong Chao Li Teaching department of Sports Qufu Normal UniversityQufu273165China Teaching department of Sports Shandong Management UniversityJinan250100China General Education Center Weifang Vocational CollegeWeifang262737China

Objective:This study was conducted to explore the relationships among sedentary behavior(SB),electronic product addiction(EPA),and depression(D)in adolescents during the COVID-19 ***:A total of 604 adolescents(including 309 girls and 295 boys aged 12-18)were selected from Qufu City,Shandong Province,China for three rounds of *** model was constructed using AMOS 23.0 software,and cross-lagged analysis was ***:SB at T1 can significantly positively predict SB and EPA at T2(p<0.05).EPA at T1 can significantly positively predict SB and D at T2(p<0.05).Physical activity level and SB at T2 can significantly predict SB and EPA at T3(p<0.05).EPA at T2 can significantly predict SB,EPA,and D at T3(p<0.05).Conclusions:SB and EPA are predictive factors for ***,SB can significantly positively predict D and indirectly predict D through the mediating effect of EPA.

关键词： COVID-19 electronic product addiction depression sedentary behavior

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Burden of routine orthopedic implant removal a single center retrospective study

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World Journal of Orthopedics 2024年第2期15卷 139-146页

作者： Ammar K AlOmran Nader Alosaimi Ahmed A Alshaikhi Omar M Bakhurji Khalid J Alzahrani Basil Ziyad Salloot Tamim Omar Alabduladhem Ahmed I AlMulhim Arwa Alumran department of Orthopedic College of MedicineImam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia Health Information management and Technology department Imam Abdulrahman Bin Faisal UniversityDammam 31441Saudi Arabia

BACKGROUND Open reduction and internal fixation represent prevalent orthopedic procedures,sparking ongoing discourse over whether to retain or remove asymptomatic *** consensus on this matter is paramount for orthopedic *** study aims to quantify the impact of routine implant removal on patients and healthcare facilities.A retrospective analysis of implant removal cases from 2016 to 2022 at King Fahad Hospital of the University(KFHU)was conducted and subjected to statistical *** these cases,44%necessitated hospitalization exceeding one day,while 56%required only a single *** exhibited a 55%need for extended hospital stays,contrasting with 22.8%among the pediatric *** complication rate was 6%,with all patients experiencing at least one ***,34.1%required sick leave and 4.8%exceeded 14 *** anesthesia was predominant(88%).Routine implant removal introduces unwarranted complications,particularly in adults,potentially prolonging *** procedure strains hospital resources,tying up the operating room that could otherwise accommodate critical *** defined institutional guidelines are imperative to regulate this *** To measure the burden of routine implant removal on the patients and *** This is a retrospective analysis study of 167 routine implant removal cases treated at KFHU,a tertiary hospital in Saudi *** were collected in the orthopedic department at KFHU from February 2016 to August 2022,which includes routine asymptomatic implant removal cases across all age *** indications such as infection,pain,implant failure,malunion,nonunion,restricted range of motion,and prominent hardware were *** who had external fixators removed or joints replaced were also *** Between February 2016 and August 2022,360 implants were retrieved;however,only 167 of those who met the inclusion criteria were included in this

关键词： Implant removal Healed fracture Orthopedic implant Complications Healthcare system

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Nitrogen and phosphorus fertilization leads to soil arbuscular mycorrhizal fungal diversity changes and rainfed crop yield increase on the Loess Plateau of China:A 37-year study

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Pedosphere 2024年第2期34卷 328-338页

作者： Yi WANG Wenting ZHANG Chunyue LI Shun CHANG Yu MIAO Qianxue LI Zhaoyang KOU Tinghui DANG State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi'an 710061China School of Geography and tourism Shaanxi Normal UniversityXi'an 710119China Institute of Soil and Water Conservation Northwest A&F UniversityYangling 712100China

More than 80%of plants form mutualistic symbiotic relationships with arbuscular mycorrhizal fungi(AMF),and the application of fertilizers,such as nitrogen(N)and phosphorus(P)fertilizers,is a common agricultural management practice to improve crop yield and ***,the potential effects of long-term N and P fertilization on the AMF community in the rainfed agricultural system of the Loess Plateau of China are still not well *** this study,a long-term field experiment was conducted based on orthogonal design,with three N levels(0,90,and 180 kg ha^(-1)year^(-1))and three P levels(0,90,and 180 kg ha^(-1)year^(-1))for wheat *** in AMF community and correlations between AMF community composition,soil environmental factors,and wheat yield component traits were analyzed using traditional biochemical methods and high-throughput sequencing *** results showed that long-term N and P addition had a significant effect on the AMF community structure and *** application alone significantly reduced the richness and diversity of AMF community,whereas the combined application of N and P significantly increased the richness and diversity of AMF *** AMF community was driven mainly by soil available P,total P,and *** was a significant positive correlation between Glomus abundance and wheat yield and a significant negative correlation between Paraglomus abundance and wheat ***-term N and P addition directly increased crop yield and affected yield indirectly by influencing soil chemical properties and the AMF *** application of N and P both at90 kg ha^(-1)year^(-1)could improve the ecological and physiological functions of the AMF community and benefit the sustainable development of rainfed agriculture.

关键词： Glomus long-term fertilization microbial community Paraglomus rainfed agriculture wheat

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