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Event-triggered receding horizon control via actor-critic design

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Science China(Information Sciences) 2020年第5期63卷 131-145页

作者： Lu DONG Xin YUAN Changyin SUN School of Automation Southeast University College of Electronics and Information Engineering Tongji University Key Laboratory of Measurement and Control of Complex Systems of Engineering Ministry of EducationSoutheast University

In this paper, we propose a novel event-triggered near-optimal control for nonlinear continuoustime systems. The receding horizon principle is utilized to improve the system robustness and obtain better dynamic control performance. In the proposed structure, we first decompose the infinite horizon optimal control into a series of finite horizon optimal problems. Then a learning strategy is adopted, in which an actor network is employed to approximate the cost function and an critic network is used to learn the optimal control law in each finite horizon. Furthermore, in order to reduce the computational cost and transmission cost, an event-triggered strategy is applied. We design an adaptive trigger condition, so that the signal transmissions and controller updates are conducted in an aperiodic way. Detailed stability analysis shows that the nonlinear system with the developed event-triggered optimal control policy is asymptotically *** results on a single-link robot arm with different noise types have demonstrated the effectiveness of the proposed method.

关键词： event-triggered control receding horizon control actor-critic design optimal control nonlinear systems neural networks

E-Commerce Supply Chain Process Optimization Based on Whole-Process Sharing of Internet of Things Identification Technology

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Computer Modeling in Engineering & Sciences 2021年第2期126卷 843-854页

作者： Shiyan Xu Jun Chen Maoguo Wu Chenyang Zhao School of Economics and Management Tongji UniversityShanghai200092China SILC Business School Shanghai UniversityShanghai201800China

With in-depth development of the Internet of Things(IoT)in various industries,the informatization process of various industries has also entered the fast *** article aims to solve the supply chain process problem in e-commerce,focusing on the specific application of Internet of Things technology in *** logistics is an important link in today’s e-commerce *** article proposes a distributed analysis method for RFID-based e-commerce warehousing process optimization and an e-commerce supply chain management process based on Internet of Things *** article first introduces the advantages and disadvantages of shared IoT identification technology and the IoT resource sharing platform based on the three-layer abstract data model and representational state transfer(REST)*** actual IoT applications and the characteristics of an existing platform,a REST-based IoT resource sharing platform is *** with actual projects,a REST-based IoT resource sharing platform was built,and key technology experiments were conducted for ***,optimizing the e-commerce supply chain management process under Internet of Things technology and explaining the advantages of optimized e-commerce supply chain management are *** on this subject provides a theoretical basis for the application of the Internet of Things in e-commerce and has practical significance and practical value for managing service capabilities and service levels in e-commerce.

关键词： Shared IoT identification technology e-commerce supply chain process optimization

Extracorporeal membrane oxygenation for lung cancer-related life-threatening hypoxia:A case report

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World Journal of Clinical Cases 2022年第25期10卷 8974-8979页

作者： Seung Soo Yoo Shin Yup Lee Sun Ha Choi Department of Internal Medicine Kyungpook National UniversityDaegu 41404South Korea Lung cancer center Kyungpook National University Chilgok HospitalDaegu 41404South Korea

BACKGROUND Life-threatening hypoxia can occur in patients with lung cancer due to bronchial *** membrane oxygenation(ECMO)can be used as a bridge therapy for patients with severe hypoxia not relieved by conventional mechanical ***,the usefulness of chemotherapy in patients with lung cancer receiving ECMO therapy is not well *** SUMMARY A 53-year-old man visited the emergency room with worsening dyspnea for 1 mo.A series of imaging and diagnostic tests were performed,and stageⅢB(cT4N2M0)lung cancer was eventually *** hospital day 3,he experienced dyspnea and hypoxia that was not relieved with oxygen support via a high-flow nasal *** was initiated because his respiratory condition did not improve even with mechanical *** patient then underwent gemcitabine/cisplatin chemotherapy without dose reduction while on *** two cycles of chemotherapy,there was a decrease in the size of the primary tumor in the right main *** the completion of concurrent chemoradiotherapy,a computed tomography scan revealed further improvement in the right main bronchus *** months after a lung cancer diagnosis,the patient did well without any *** ECMO is a potential bridge therapy for respiratory failure in patients with central airway obstruction secondary to lung cancer.

关键词： Extracorporeal membrane oxygen Lung cancer Hypoxia Respiratory failure Chemoradiotherapy Case report

Aspiration as the first-choice procedure for airway management in an infant with large epiglottic cysts: A case report

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World Journal of Clinical Cases 2022年第23期10卷 8249-8254页

作者： Jian-Qiao Zheng Li Du Wei-Yi Zhang Department of Anesthesiology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Anesthesiology Sichuan Cancer Hospital and InstituteSichuan Cancer CenterSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengdu 610041Sichuan ProvinceChina

BACKGROUND Epiglottic cysts is a rare but potentially lethal supraglottic airway pathology in infants due to the high risk of cannot intubation or cannot *** fiberoptic intubation appeared to be the safest technique,but it is very challenging in infants with large epiglottic *** it has the risk of airway *** report that cyst aspiration is an effective treatment as the first-choice procedure for airway management in an infant with large epiglottic *** SUMMARY A 46-day-old male infant weighing 2.3 kg presented to the emergency room with difficulty feeding,worsening stridor,and progressive respiratory *** cysts was diagnosed,but fibro bronchoscopy examination failed,as the fiberoptic bronchoscope was unable to cross the epiglottic cysts to the *** infant was transferred to the operating room for emergency cystectomy under general *** respiration was maintained during anesthesia induction,and cyst aspiration was performed as the first procedure for airway management under video laryngoscopy considering that the preoperative fibro bronchoscopy examination ***,the endotracheal tube was intubated *** was performed uneventfully,and the infant was safely transferred to the intensive care unit after *** infant was extubated smoothly on the third postoperative day and discharged on the eighth day after *** follow-up 1 year after the surgery,a normal airway was found by fibro bronchoscopy *** Epiglottic cyst aspiration can be considered the first procedure for airway management in infants with large epiglottic cysts.

关键词： Epiglottic cysts Infant Airway management Difficult airway Case report

Biogenic Sediments and Their Paleoceanographic Implication in West Pacific Warm Pool during the Pleistocene

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Journal of Earth Science 2010年第1期21卷 42-54页

作者：王汝建肖文申 State Key Laboratory of Marine Geology Tongji University Alfred Wegener Institute for Polar and Marine Research

Primary productivity has played an important role in the global carbon cycle during the Quaternary. The average Corg/N ratio was 7.0 from the core MD97-2140 in the West Pacific Warm Pool （WPWP） over the last 1 755 ka, which indicates a main contribution of marine organic carbon to the organic matter in the sediments. Large fluctuations in mass accumulation rates （MARs） of biogenics and lithogenics from this core since the marine isotope stage （MIS） 6 reflected the moderate variability in oceanographic condition, while tittle fluctuations in MAR-biogenics and -lithogenics from the MIS 59 to MIS 7 implied the relatively stable and uniform oceanographic condition, although the sea surface temperatures （SSTs） probably fluctuated by ca. 5 ℃. MAR-organic since the MIS 6 increased evidently during the glacial periods, which ascribed to terrestrial inputs, including lithogenic matter and dissolved nutrient, which also contribute to stimulating primary productivity. The results compared among the four cores in the WPWP since the MIS 9 indicate that in the western sector with the shallow thermocline, high primary productivity during the glacial periods was controlled by wind-induced surface water mixing, upwelling, and terrestrial inputs, while in the central and eastern sectors, the little different medium to low productivity might have been made by more intense upweil- ing driven by strong winds because the thicker warm surface water pool and the deeper thermocline prevented nutrient-bearing water from upwelling to upper water column even during the glacial times.

关键词： biogenic sediment paleoceanographic implication West Pacific Warming Pool Pleistocene.

Neogene oxygen isotopic stratigraphy,ODP Site 1148,northern South China Sea

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Science China Earth Sciences 2001年第10期44卷 934-942页

作者：赵泉鸿翦知湣王吉良成鑫荣黄宝琦徐建周震房殿勇汪品先 1. Key Laboratory of Marine Geology Ministry of Education Tongji University 200092 Shanghai China

A detailed stable isotopic study based on benthic foraminifera from 1165 samples of ODP Site 1148 (18° 50.17.3’N, 116° 33.93’E, water depth 3308.3 m), northern South China Sea, provides an excellent oxygen isotopic record with an average resolution of 30 ka. It contains the most continuous δ18O data with highest resolution for the whole Neogene sequence in the world. The δ18O curve shows a step-like increasing upwards and records 5 increases, 3 decreases and 2 stable stages during the Neogene, reflecting the general trend of global cooling. Among these events the δ18O decrease at 17.2–14.5 Ma, and two δ18O increases at 14.5-13.6 and 3.0-2.4 Ma are most marked and globally comparable. The intervals at 13.6-10.2 and 6.0-3.0 Ma with the lowest-amplitude and least fluctuation in δ18O represent the most stable bottom water periods for the South China Sea.

关键词： oxygen stable isotope benthic foraminifera stratigraphy paleoceanography Neogene South China Sea

Epigenetic silencing of BEND4,a novel DNA damage repair gene,is a synthetic lethal marker for ATM inhibitor in pancreatic cancer

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Frontiers of Medicine 2024年第4期18卷 721-734页

作者： Yuanxin Yao Honghui Lv Meiying Zhang Yuan Li James G.Herman Malcolm V.Brock Aiai Gao Qian Wang Francois Fuks Lirong Zhang Mingzhou Guo Department of Gastroenterology and Hepatology the First Medical CenterChinese PLA General HospitalBeijing100853China Department of Pharmacology School of Basic Medical SciencesZhengzhou UniversityZhengzhou450001China Henan Institute of Advanced Technology Zhengzhou UniversityZhengzhou450001China UPMC Hillman cancer center University of Pittsburgh Medical CenterPittsburghPA15213USA Department of surgery School of MedicineJohns Hopkins School of MedicineBaltimoreMD21287USA Laboratory of cancer Epigenetics Faculty of MedicineULB-Cancer Research Center(U-CRC)Universite Libre de Bruxelles(ULB)Brussels1070Belgium National Key Laboratory of Kidney Diseases the First Medical CenterChinese PLA General HospitalBeijing100853China

Synthetic lethality is a novel model for cancer *** understand the function and mechanism of BEN domain-containing protein 4(BEND4)in pancreatic cancer,eight cell lines and a total of 492 cases of pancreatic neoplasia samples were included in this ***-specific polymerase chain reaction,CRISPR/Cas9,immunoprecipitation assay,comet assay,and xenograft mouse model were ***4 is a new member of the BEN domain *** expression of BEND4 is regulated by promoter region *** is methylated in 58.1%(176/303)of pancreatic ductal adenocarcinoma(PDAC),33.3%(14/42)of intraductal papillary mucinous neoplasm,31.0%(13/42)of pancreatic neuroendocrine tumor,14.3%(3/21)of mucinous cystic neoplasm,4.3%(2/47)of solid pseudopapillary neoplasm,and 2.7%(1/37)of serous cystic ***4 methylation is significantly associated with late-onset PDAC(>50 years,P<0.01)and tumor differentiation(P<0.0001),and methylation of BEND4 is an independent poor prognostic marker(P<0.01)in ***,BEND4 plays tumor-suppressive roles in vitro and in ***,BEND4 involves non-homologous end joining signaling by interacting with Ku80 and promotes DNA damage *** of BEND4 increased the sensitivity of PDAC cells to ATM ***,the present study revealed an uncharacterized tumor suppressor BEND4 and indicated that methylation of BEND4 may serve as a potential synthetic lethal marker for ATM inhibitor in PDAC treatment.

关键词： BEND4 DNA methylation synthetic lethality NHEJ pathway

Rates of bacterial sulfate reduction and their response to experimental temperature changes in coastal sediments of Qi'ao Island, Zhujiang River Estuary in China

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Acta Oceanologica Sinica 2014年第8期33卷 10-17页

作者： WU Zijun ZHOU Huaiyang PENG Xiaotong LI Jiangtao CHEN Guangqian State Key Laboratory of Marine Geology Tongji University Guangzhou Institute of Geochemistry Chinese Academy of Sciences

Subtropical sediment cores （QA09-1 and QA12-9） from the coastal zone of Qi’ao Island in the Zhujiang River Estuary were used to determine the rates of sulfate reduction and their response to experimental tempera-ture changes. The depth distribution of the sulfate reduction rates was measured from whole-core incu-bations with radioactive tracer35SO42-, and peaks of 181.19 nmol/（cm3·d） and 107.49 nmol/（cm3·d） were exhibited at stations QA09-1 and QA12-9, respectively. The profiles of the pore water methane and sulfate concentrations demonstrated that anaerobic oxidation of methane occurred in the study area, which result-ed in an increase in the sulfate reduction rate at the base of the sulfate-reducing zone. Meanwhile, the sulfate concentration was not a major limiting factor for controlling the rates of sulfate reduction. In addition, the incubation of the sediment slurries in a block with a temperature gradient showed that the optimum tem-perature for the sulfate reduction reaction was 36°C. The Arrhenius plot was linear from the lowest tempera-ture to the optimum temperature, and the activation energy was at the lower end of the range of previously reported values. The results suggested that the ambient temperature regime of marine environments prob-ably selected for the microbial population with the best-suited physiology for the respective environment.

关键词： sulfate reduction rate temperature-gradient incubations 35SO42- tracer Qi’ao Island

A Dynamic Road Incident Information Delivery Strategy to Reduce Urban Traffic Congestion

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IEEE/CAA Journal of Automatica Sinica 2018年第5期5卷 934-945页

作者： Liang Qi Mengchu Zhou Wenjing Luan IEEE Department of Computer Scicnce and Technology Shandong University of Science and TechnologyQingdao 266590China Department of Computer Science Tongji UniversityShanghai 201804China Department of Electrical and Computer Engineering New Jersey Institute of TechnologyNewark NJ 07102USA Key Laboratory of Embedded System and Service Computing Ministry of EducationShanghai Electronic Transactions and Information Service Collaborative Innovation CenterDepartment of Com-puter ScienceTongji UniversityShanghai 201804China

Advanced information and communication technolo-gies can be used to facilitate traffic incident *** an incident is detected and blocks a road link,in order to reduce the incident-induced traffic congestion,a dynamic strategy to deliver incident information to selected drivers and help them make detours in urban areas is proposed by this ***-dependent shortest path algorithms are used to generate a subnetwork where vehicles should receive such information.A simulation approach based on an extended cell transmission model is used to describe traffic flow in urban networks where path information and traffic flow at downstream road links are well *** results reveal the influences of some major parameters of an incident-induced congestion dissipation process such as the ratio of route-changing vehicles to the total vehicles,operation time interval of the proposed strategy,traffic density in the traffic network,and the scope of the area where traffic incident information is *** results can be used to improve the state of the art in preventing urban road traffic congestion caused by incidents.

关键词： Cell transmission model(CTM) intelligent transportation systems(ITS) traffic incident management(TIM) urban traffic congestion