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Woody plant cell walls:Fundamentals and utilization

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Molecular Plant 2024年第1期17卷 112-140页

作者： Wei Li Ying-Chung Jimmy Lin Ying-Lan Chen Chenguang Zhou Shuang Li Nette De Ridder Dyoni M.Oliveira Lanjun Zhange Baocai Zhang Jack P.Wang Changzheng Xu Xiaokang Fu Keming Luo Ai-Min Wu Taku Demura Meng-Zhu Lu Yihua Zhou Laigeng Li Toshiaki Umezawa Wout Boerjan Vincent L.Chiang State Key Laboratory of Tree Genetics and Breeding Northeast Forestry UniversityHarbin 150040China Department of Life Science National Taiwan UniversityTaipeiTaiwanChina Department of Biotechnology and Bioindustry Sciences College of Bioscience and BiotechnologyNational Cheng Kung UniversityTainanTaiwanChina Department of Plant Biotechnology and Bioinformatics Ghent UniversityTechnologiepark 719052 GhentBelgium VIB Center for Plant Systems Biology Technologiepark 719052 GhentBelgium State Key Laboratory of Plant Genomics Insttute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Forest Biotechnology group Department of Forestry and Environmental ResourcesNorth Carolina State UniversityRaleighNC 27695USA Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation Integrative Science Center of Germplasm CreationSchool of Life SciencesSouthwest UniversityChongqing 400715China Guangdong Key Laboratory for Innovative Developmentand Utilization of Forest Plant Germplasm College of Forestry and Landscape ArchitecturesSouth China Agricultural UniversityGuangzhou510642China Center for Digital Green-innovation Nara Institute of Science and TechnologykomaNara 630-0192Japan State Key Laboratory of Subtropical Siviculture College of Forestry and BiotechnologyZhejang A&F UniversityHangzhou 311300China CAS Center for Excellence in Molecular Plant Sciences Chinese Academy of Sciences300 Fenglin RoadShanghai 200032China Laboratoryof MetabolicScienceofForest Plants and Microorganisms Rsearch Institute for Sustainable HumanosphereKyoto UniversityUjiKyoto 611-0011 Japan

cell walls in plants,particularly forest trees,are the major carbon sink of the terrestrial *** and biosynthetic features of plant cell walls were revealed early on,focusing mostly on herbaceous model *** developments in genomics,transcriptomics,epigenomics,transgenesis,and associated analytical techniques are enabling novel insights into formation of woody cell ***,we review multilevel regulation of cell wall biosynthesis in forest tree *** highlight current approaches to engineering cell walls as potential feedstock for materials and energy and survey reported field tests of such engineered transgenic *** outline opportunities and challenges in future research to better understand cell type biogenesis for more efficient wood cell wall modification and utilization for biomaterials or for enhanced carbon capture and storage.

关键词： regulation of cell wall formation biosynthesis of cell wall components lignin cellulose hemicellulose cell wall utilization

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Preface

Journal of Computer Science & Technology 2010年第1期25卷 1-2页

作者： Ying Xu Ming Li Tao Jiang Department of Biochemistry and Molecular Biology and Institute of Bioinformatics The University of Georgia Athens U.S.A. D.R. Cheriton School of Computer Science University of Waterloo Waterloo Canada Department of Computer Science and engineering University of California Riverside U.S.A.

Bioinformatics is considered as one of the fastest growing fields in science today, thanks to the rapidly expanding and advancing capabilities in biological data collection from cellular organisms using high-throughput measurement technologies. These data reflect different aspects of living organisms such as the existence, structure, functionality and functional states of biological molecules and assemblies under designed experimental conditions. The enormous amount of information hidden in these data allows computational scientists to start to elucidate the internal structures and control mechanisms of biological systems at various levels such as cell, tissue, organ, organism and eco-system in a systematic manner, and even possibly to derive the organizational and operating principles of such systems. Scientists have begun to draw comparisons between the relationship of physics and mathematics and that of biology and computational science, and believe that the future of biology could be taught, like physics, “as a set of basic systems duplicated and adapted to a very wide range of cellular and organismal functions, following basic evolutionary principles constrained by the Earth＇s geological history”（T. F. Smith, The challenges facing genomic informatics. Current Topics in Computational Molecular Biology, T. Jiang, Y. Xu and M. Q. Zhang （eds.）, pp.3-8, MIT Press, Cambridge, Massachusetts （2002）.）. It is clearly exciting to possibly play a role in helping to transform biological science from a pure experimental science to a science like physics. Yet the gap between where we are now and where we want to be is enormously large! It is generally believed that computational scientists can and should play essential roles in bridging this gap by offering new techniques, frameworks and possibly theories for solving a variety of computational challenges arising in modern biology.

关键词： data collection capabilities structure existence different aspects

Development and assessment of a cutaneous tissue stretch device as a novel scar therapy

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Plastic and Aesthetic Research 2016年第1期3卷 351-358页

作者： Jonathan Kanevsky Joshua Vorstenbosch Julian Diaz-Abele Tyler Safran Markus Prinz Youssef Tahiri Mirko Gilardino Satya Prakash Division of Plastic and Reconstructive Surgery McGill University Health CentreMontrealQC H3G 1B3Canada Section of Plastic and Reconstructive Surgery University of ManitobaWinnipegMB R3T 2N2Canada McGill Medical School McGill UniversityMontrealQC H3G 2M1Canada Division of General Surgery University of SherbrookeSherbrookeQC J1K 2R1Canada Division of Plastic and Reconstructive Surgery Indiana UniversityIndianapolisIN 46202USA Biomedical engineering Department Artificial Cells and Organs Research CentreMontrealQC H3A 2B4Canada

Aim:Scar prevention and reduction is an area of therapeutic opportunity and unmet medical *** no current effective scar therapy,patients are often disappointed in their appearance post surgery and re-present to surgeons,only to be turned *** purpose of this study was to develop and test a device that produces intermittent parallel stretch on new scars and to analyze its potential to reduce ***:Mice were randomized into 5 scar stretch treatment groups:1 control,1 sham,and 3 stretch models(0.5×,1×,or 2×device strength)and treated for 10 *** were scored using the Vancouver Scar *** tissue samples were compared by histology and transforming growth factor beta 1(TGF-β1)expression between control and treatment ***:Scar scores of 0.5×and 1×groups were significantly lower than the control group(Pgroup were also significantly lower than the 0.5×group(Pgroups showed more collagen deposition and a thicker dermal scar than the 0.5×and 1×*** scars had fewer fibroblasts with more collagen deposition than the 0.5×and 2×***-β1 levels were significantly lower in the 0.5×(342.1±9.2)and 1×(254.1±3.1)groups than in the control group(Pgroup were also significantly lower than the 0.5×treatment group(Ptissue stretch parallel to scars during the proliferative phase of wound healing decreases fibrosis on a macroscopic,microscopic and biochemical level.

关键词： Mechanotransduction scar therapy hypertrophic scar skin stretch

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肝脏干细胞研究及应用前景展望

中国组织工程研究 2012年第6期16卷 1119-1124页

作者：王楠邹伟刘鹏崔占峰刘晶大连医科大学附属第一医院中英再生医学应用研究中心辽宁省大连市116011 辽宁师范大学生命科学学院辽宁省大连市116029 Department of engineering Science University of Oxford

背景:近年肝脏干细胞移植治疗终末期肝病得到人们的广泛关注,但临床应用中却面临来源有限,细胞数量不足,移植后干细胞往往弥散、流失,且分化率低,无法有效发挥其修复功能等技术问题制约。目的:总结肝脏干细胞组织工程的研究进展,并展望... 详细信息

背景:近年肝脏干细胞移植治疗终末期肝病得到人们的广泛关注,但临床应用中却面临来源有限,细胞数量不足,移植后干细胞往往弥散、流失,且分化率低,无法有效发挥其修复功能等技术问题制约。目的:总结肝脏干细胞组织工程的研究进展,并展望其应用前景。方法:应用计算机检索1999-01/2010-12 PubMed数据库相关文献,英文检索词"liver stem cell tissue engineering"分别与"three dimensional culture,biodegradable materials,biological reactor"组合,并限定文献语言种类为English。共检索到文献241篇,最终纳入符合标准的文献43篇。结果与结论:肝脏干细胞来源有限,而肝脏组织工程需要大量可靠的种子干细胞,三维培养是目前发现行之有效的体外扩增手段。在三维培养条件下,使用不同支架材料和反应器扩增效率及移植效果存在巨大差异,如何确定具有肝脏干细胞特异性的理想扩增条件、改善支架生物相容性以提高移植效率是关键技术问题。未来的研究需要进一步探讨肝脏干细胞特异性扩增生物反应器及肝脏干细胞特异性支架构建等技术难点。

关键词：肝脏干细胞组织工程三维培养生物可降解材料生物反应器综述文献

氟化钾化学转化涂层提高镁合金血管支架耐蚀性和生物相容性

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中国医药导刊 2015年第B5期17卷 1-8页

作者：毛琳 Kwak Minsuk 陈佳慧沈雳 Fan Rong 袁广银上海交通大学轻合金精密成型国家工程研究中心及金属基复合材料国家重点实验室上海200240 Department of Biomedical engineering Yale University 复旦大学中山医院心脏病学中心上海200032

镁合金是能够同时满足工程学和医学的短期结构支撑类生物材料.然而,耐蚀性能差制约着生物镁合金的广泛应用.本文中我们通过一种简单的化学转化处理方法,在Mg-Nd-Zn-Zr合金（简称JDBM）表面制备了一层均匀的纳米级MgF2涂层,以提高基体的... 详细信息

镁合金是能够同时满足工程学和医学的短期结构支撑类生物材料.然而,耐蚀性能差制约着生物镁合金的广泛应用.本文中我们通过一种简单的化学转化处理方法,在Mg-Nd-Zn-Zr合金（简称JDBM）表面制备了一层均匀的纳米级MgF2涂层,以提高基体的耐腐蚀性能和生物相容性.体外腐蚀性能研究结果表明,由于膜层的保护作用,JDBM基体的腐蚀速率从（0.337±0.021）mm/y下降到（0.269±0.043）mm/y,耐腐蚀性能提高了约20%.MgF2膜层表面鳞片尺寸在200～300nm,有利于内皮细胞的粘附、增殖和细胞间的排列取向.动物实验结果表明,鳞片状MgF2膜层有利于促进表面内皮化,提高支架的组织相容性.

关键词：镁合金表面处理体外降解细胞粘附内皮化

Inflammatory Mechanism of Total Flavonoids of Chrysanthemum and Medicated Serum on Castrated Dry Eye Animal and cell Models

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Digital Chinese Medicine 2020年第4期3卷 283-296页

作者： SHI Jian CHEN Li-Hao LIU Qian-Hong PENG Jun TANG Yu YAO Xiao-Lei LIU Zu-Guo Hunan University of Chinese Medicine ChangshaHunan 410208China Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine ChangshaHunan 410208China Hunan Provincial engineering and Technological Research Center for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine and Protecting Visual Function ChangshaHunan 410208China Department of Ophthalmology The First Hospital of Hunan University of Chinese MedicineChangshaHunan 410007China Fujian Provincial Key Laboratory of Ophthalmology and Visual Science Eye Institute of Xiamen UniversitySchool of MedicineXiamen UniversityXiamenFujian 361102China Xiamen Eye Center of Xiamen University XiamenFujian 361001China Department of Ophthalmology The First Affiliated Hospital of University of South ChinaHengyangHunan 421001China

Objective To observe the effects of total flavonoids of chrysanthemum and medicated serum on the expression of related proteins in the lacrimal tissue and dry-eye cell models of male rabbits with dry eye caused by ***(1)150 male Japanese rabbits were randomly divided into five groups,with 30 rabbits in each group:normal control group(group A),sham group(group B),model group(group C),androgen control group(group D)and total flavonoids of chrysanthemum treatment group(group E).The androgen deficiency dry-eye model was established by bilateral castration in groups C,D and *** saline was administered to groups A,B and C by gavage;androgen(testosterone propionate)was injected into muscle in group D;and group E was given total flavonoids of chrysanthemum by *** white rabbits were tested the Schirmer I test(SIT)and tear break-up time(BUT).After euthanasia,tear gland tissue was harvested so that we could observe pathological changes in the expression of related inflammatory factors in the lacrimal gland *** expression of interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α)and transforming growth factor-β1(TGF-β1)was detected in the lacrimal gland tissue by *** transcription PCR was used to quantitatively detect expression of TGF-β1 mRNA.(2)Male Wistar rat lacrimal epithelial cells were used to establish a model of eye stem cell apoptosis caused by androgen *** blank control group was set up without androgen culture,the control group with androgen culture,and the total flavonoids of chrysanthemum group without *** MTT method was used to determine the optimal intervention dosage of drug-containing *** blot and QPCR were used to detect the expression of AR mRNA,NF-κB phosphorylated protein and TGF-β1 in lacrimal epithelial cells,and the androgen-like effect of total flavonoids of chrysanthemum was ***(1)Immunohistochemistry showed that groups A,B,D and E had significantly lower e

关键词： Total flavonoids of chrysanthemum Dry eye disease Interleukin-1β(IL-1β) Tumor necrosis factor-α(TNF-α) Transforming growth factor-β1(TGF-β1) Androgen receptor(AR) Nuclear factor-к-gene binding(NF-кB)

Ionized jet deposition of antimicrobial and stem cell friendly silver-substituted tricalcium phosphate nanocoatings on titanium alloy

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Bioactive Materials 2021年第8期6卷 2629-2642页

作者： Gabriela Graziani Katia Barbaro Inna V.Fadeeva Daniele Ghezzi Marco Fosca Enrico Sassoni Gianluca Vadalà Martina Cappelletti Francesco Valle Nicola Baldini Julietta V.Rau IRCSS Istituto Ortopedico Rizzoli Laboratory of NanoBiotechnologyvia di Barbiano 1/1040136BolognaItaly Istituto Zooprofilattico Sperimentale Lazio e Toscana“M.Aleandri” Via Appia Nuova 1411-00178RomeItaly A.A.Baikov Institute of Metallurgy and Materials Science Russian Academy of SciencesLeninsky prospect 49119334MoscowRussia Istituto di Struttura della Materia Consiglio Nazionale delle Ricerche(ISM-CNR)Via del Fosso del Cavaliere100-00133RomeItaly University of Bologna Department of CivilChemicalEnvironmental and Materials Engineeringvia Terracini 2840131BolognaItaly UniversitàCampus Bio-Medico di Roma Research Unit of Orthopaedic SurgeryFaculty of Medicine and SurgeryVia Alvaro del Portillo 2100128RomeItaly University of Bologna Department of Pharmacy and Biotechnologyvia Irnerio 4240126BolognaItaly Institute of Nanostructured Materials National Research Council(ISMN-CNR)Via Piero Gobetti10140129BolognaItaly IRCSS Istituto Ortopedico Rizzoli BST Biomedical Science and Technologies Labvia di Barbiano 1/1040136BolognaItaly University of Bologna Department of Biomedical and Neuromotor SciencesVia Massarenti940128BolognaItaly Sechenov First Moscow State Medical University Institute of PharmacyDepartment of AnalyticalPhysical and Colloid ChemistryTrubetskaya 8build.2119991MoscowRussia

Orthopedic infections pose severe societal and economic burden and interfere with the capability of the implanted devices to integrate in the host bone,thus significantly increasing implants failure *** address infection and promote integration,here nanostructured antibacterial and bioactive thin films are proposed,obtained,for the first time,by Ionized Jet Deposition(IJD)of silver-substituted tricalcium phosphate(Ag-TCP)targets on *** morphology,composition and mechanical properties are characterized and proof-of-concept of biocompatibility is *** efficacy is investigated against four Gram positive and Gram negative bacterial strains and against *** fungus,by investigating the modifications in planktonic bacterial growth in the absence and presence of ***,for all bacterial strains,the capability of the film to inhibit bacterial adhesion is also *** indicate that IJD permits a fine control over films composition and morphology and deposition of films with suitable mechanical *** studies show a good efficacy against Escherichia coli,Staphylococcus aureus,Pseudomonas aeruginosa,Enterococcus faecalis and against fungus Candida albicans,with evidences of efficacy against planktonic growth and significant reduction of bacterial cell *** cytotoxic effects are evidenced for equine adipose tissue derived mesenchymal stem cells(ADMSCs),as no reductions are caused to cells viability and no interference is assessed in cells differentiation towards osteogenic lineage,in the presence of ***,thanks to nanostructuration and biomimetic composition,tricalcium phosphate(TCP)coatings favor cells viability,also when *** findings show that silver-substituted nanostructured coatings are promising for orthopedic implant applications.

关键词： Tricalcium phosphate Silver Nanostructured coatings Antibacterial coatings Orthopedics Antibacterial ceramics

短波红外荧光成像活体监测和评估植入的M2巨噬细胞在骨骼肌再生中的作用（英文）

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engineering 2024年第2期 283-294页

作者： Mo Chen Yuzhou Chen Sijia Feng Shixian Dong Luyi Sun Huizhu Li Fuchun Chen Nguyen Thi Kim Thanh Yunxia Li Shiyi Chen You Wang Jun Chen Sports Medicine Institute of Fudan University Department of Sports Medicine Huashan Hospital Fudan University Department of Bone and Joint Surgery Department of Orthopedics Renji Hospital School of Medicine Shanghai Jiao Tong University Department of Anatomy and Physiology School of Medicine Shanghai Jiao Tong University Key Laboratory of Infrared System Detection & Imaging Technology Shanghai Institute of Technical Physics Chinese Academy of Sciences Biophysics group Department of Physics and Astronomy University College London Healthcare Biomagnetics and Nanomaterials Laboratories University College London

Skeletal muscle has a robust regeneration ability that is impaired by severe injury,disease,and *** in a decline in skeletal muscle ***,improving skeletal muscle regeneration is a key challenge in treating skeletal muscle-related *** to their significant role in tissue regeneration,implantation of M2 macrophages(M2M?) has great potential for improving skeletal muscle ***,we present a short-wave infrared(SWIR) fluorescence imaging technique to obtain more in vivo information for an in-depth evaluation of the skeletal muscle regeneration effect after M2M? *** fluorescence imaging was employed to track implanted M2M? in the injured skeletal muscle of mouse *** is found that the implanted M2M? accumulated at the injury site for two ***,SWIR fluorescence imaging of blood vessels showed that M2M? implantation could improve the relative perfusion ratio on day 5(1.09±0.09 vs 0.85±0.05;p=0.01) and day 9(1.38±0.16 vs 0.95±0.03;p=0.01) post-injury,as well as augment the degree of skeletal muscle regencration on day 13 ***,multiple linear regression analyses determined that post-injury time and relative perfusion ratio could be used as predictive indicators to evaluate skeletal muscle *** results provide more in vivo details about M2M? in skeletal muscle regeneration and confirm that M2M? could promote angiogenesis and improve the degree of skeletal muscle repair,which will guide the research and development of M2M? implantation to improve skeletal muscle regeneration.

关键词：

Skin Slice as a Model for the Investigation of the Role of Mast cells in Acupuncture Effects

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Journal of Acupuncture and Tuina Science 2008年第6期6卷 367-367页

作者：汪丽娜丁光宏顾全保 Wolfgang SCHWARZ Shanghai Research Center for Acupuncture and Meridians Shanghai 201203P.R.China Department of Mechanics and Engineering ScienceFudan UniversityShanghai 200443P.R.China Shanghai Research Center for Acupuncture and Meridians Shanghai 201203P.R.China Max-Planck-Institute for BiophysicsFrankfurt/MainGermany

Objective:To establish a new and better model to investigate the properties of mast cells that couldbe involved in acupuncture process ***:Connective tissue under the corium at thearea of acupuncture point Zusanli(ST 36)from rat was acutely bluntly separated with forceps andscissors,and incubated in bath solution up to several *** cells in slices of that tissue wereirradiated with laser light of 650 nm,and changes in the appearance were observed under *** addition,patch-clamp technique in whole-cell configuration was employed to induce mechano-

关键词：皮肤真皮层针刺疗法柱状细胞