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A study on oral tolerance to treat traumatic brain injury in laboratory

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外科研究与新技术 2011年第3期 199-199页

作者：张洪伟 Dept Neurosurg 2nd Hosp Tianjin Med Univ

Objective To explore the cerebral protective effects of oral tolerance therapy in rabbit-TBI-models established by lateral fluid percussion machine. Methods 58 rabbits were divided into four groups randomly (18 in con... 详细信息

关键词： oral than CSF A study on oral tolerance to treat traumatic brain injury in laboratory

The specific cytotoxicities of chimeric antigen receptor-engineered T cells on different lymphomas

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China Medical Abstracts (Internal Medicine) 2017年第4期 230-230页

作者：张蕊 Dept Hematol Oncol Tianjin 1st Centr Hosp

Objective To investigate the specific cytotoxicities of the second and the third generations of chimeric antigen receptor(CAR)-engineered T cells(CAR-T)on different *** CAR-Ts were prepared by lentivirus packaging and infection of T ***-8,ELISA and Lactate dehydrogenase cytotoxicity assay were applied to detect the proliferation capacity,the secretion

关键词： The specific cytotoxicities of chimeric antigen receptor-engineered T cells on different lymphomas

Effect of high glucose and anoxia on Amot expression in vascular endothelial cells with regard to its function in promoting angiogenesis

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China Medical Abstracts(Internal Medicine) 2014年第3期31卷 151-151页

作者：禇月颉 Dept Diabet Foot Metab Dis HospTianjin Med Univ

Objective To observe the effects of high glucose and anoxia on Amot expression in vascular endothelial cells(VECs),and explore its role in *** VECs were incubated with different glucose concentrations for 48 h,and then cultured at normal oxygen concentration or anaerobic condition for 24 *** protein expressions of p130-Amot and p80-Amot were detected by Western *** Amot expression was downregulated in VECs by siRNA,wound healing experiments and angiogenesis experiments were performed to test the

关键词： angiogenesis anaerobic incubated healing cultured wound promoting centration attenuated migration

Clinical features of patients with liver failure accompanied with non-thyroid sick syndrome

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China Medical Abstracts(Internal Medicine) 2019年第3期36卷 173-173页

作者： FENG Hongling Dept ICU Tianjin 2nd People’s Hosp

Objective To investigate clinical characteristics of patients with liver failure accompanied with non-thyroid sick syndrome(NTIS)and the predictive value for shortterm *** Ninety patients with liver failure hospitalized in tianjin Second People's hospital from January 2013 to December 2017 were retrospectively *** them,75 patients(liver failure group)were randomly selected to establish prognostic models and the other 15 were selected for model *** 75 patients at the same time of hospitalization with chronic hepatitis were randomly selected as the control *** serum free triiodothyronine(FT3),free thyroxine(FT4)and thyroid-stimulating hormone(TSH)were measured by *** clinical characteristics and survival rates 3 months after admission of patients with liver failure accompanied with NTIS were *** predictive value of the model for end-stage liver disease(MELD)score,Child-Turcotte-Pugh(CTP)score,chronic liver failure-sequential organ failure assessment(CLIF-SOFA)score,FT3-MELD model and FT3 for prognosis of liver failure were *** data were analyzed with Student's t-test and Mann-Whitney U *** data were analyzed with chi-square *** The liver failure group had significantly lower levels of FT3,TSH and albumin(Alb),but higher levels of total bilirubin(TBil),international normalized ration(INR),serum creatinine(Cr)and FT4 than the control *** was diagnosed in 50 patients with liver failure(50/75,66.67%).There were 32 deaths in patients with NTIS and 7 in patients with *** difference was statistically significant(χ2=8.654,P=0.003).INR,Cr,FT3,MELD score,CTP score and CLIF-SOFA score were significantly different between the survival and death groups(t=-3.037,t=-2,720,t=4.100,t=-4.221,t=-3.471,and t=-3.901,respectively;all P<0.01).A negative correlation was observed between FT3 and MELD score(r=-0.439,P<0.01).The area under the receiver's operating characte

关键词： patients liver specificity

Detection of chromosomal imbalance in oligodendroglial tumors by comparative genomic hybridization

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外科研究与新技术 2011年第3期 216-216页

作者：孙翠云 Dept Neuropathol Neurol InstTianjin Med Univ Gener Hosp

Objective To investigate the relationship between genomic DNA imbalance in oligodendroglial tumors and its different classification. Methods 16 oligodendrogliomas and 17 anaplastic oligodendrogliomas were investigated by comparative genomic hybridization on Paraffin-Embedded tissue samples,and the chromosomal genomic DNA imbalances were analyzed. Results Chromosome DNA imbalance rates in oligodendrogliomas

关键词： Detection of chromosomal imbalance in oligodendroglial tumors by comparative genomic hybridization

Relationship between islet α-cell function and glomerular filtration rate in type 2 diabetic patients

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China Medical Abstracts(Internal Medicine) 2013年第4期30卷 227-227页

作者：王晓宇 Dept Diabetic Nephropathy Metab Dis HospTianjin Med Univ

Objective To analyze the isletα-cell function in type 2 diabetic patients with different levels of glomerular filtration rate (eGFR) .Methods Three hundred and eighty-eight cases of type 2 diabetic patients were classified into four groups according to eGFR:glomerular hyperfiltration group,normal renal function group,mild renal dysfunction group and moderate-severe renal dysfunction *** glucose tolerance test,insulin releasing test and glucagon releasing test were conducted to

关键词： islet glomerular filtration glucagon fasting hundred hemoglobin moderate classified releasing

The correlation between free fatty acid and insulin resistance in ischemic stroke patients

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China Medical Abstracts(Internal Medicine) 2013年第4期30卷 235-235页

作者：刘怀平 Dept Med Lab Tianjin 3rd Centr Hosp

Objective To explore the level of free fatty acid (FFA) in ischemic stroke (IS) patients and its correlation with insulin resistance (IR) .Methods This study was case-control *** who were diagnosed with IS were followed up from June,2011 to September,2012in tianjin Third Central *** 180 IS patients were divied into large infarct (57) ,middle infarct (63) and small infarct (60) according to the area of *** the same time,60 healthy persons were selected as con-

关键词： infarct tianjin APOB multivariate homeostasis fasting cholesterol stepwise varia

Detection of cancer stem cell like circulating tumor cells in peripheral blood of 45 patients with gastric cancer

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China Medical Abstracts(Internal Medicine) 2016年第1期33卷 38-页

作者：李熳 Dept Gastroenterol 2nd HospTianjin Med Univ

Objective To explore the expression and significance of CD44 gastric cancer stem cell biomarker positive circulating tumor cells(CTC)in peripheral blood of patients with gastric *** From March 2010 to December 2012,45 patients with gastric cancer and 20healthy individuals were *** blood samples of all the subjects were *** expression

关键词： circulating biomarker recurrence enrolled distant metastasis staining shorter proximal maybe

Association between fragmented QRS complexes and imperfect ST-segment resolution in patients with St-elevation myocardial infarction after primary percutaneous coronary intervention

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China Medical Abstracts(Internal Medicine) 2014年第3期31卷 164-164页

作者：段雯婷 Dept Cardiol 2nd HospTianjin Med Univ

Objective To explore the relationship between fragmented QRS complexes(fQ RS)and imperfect ST-segment resolution in ST elevation myocardial infarction(STEMI)patients undergoing primary percutaneous coronary intervention(p-PCI).Methods This study included 227 consecutive patients with STEMI who underwent *** were divided into two groups:ECG with fQ RS(n=142)and without fQ RS(n=85).Baseline clinical characteristics,Gensini score,coronary angiography features and the rate of ST-segment resolution were compared between the two ***(1)

关键词： imperfect elevation complexes consecutive ejection prolonged Pearson