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Neuronal para-apoptosis after acute brain trauma in rats

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外科研究与新技术 2003年第2期 100-100页

作者：杨新宇 Dept Neurosurg Gener Hosp Tianjin Med Univ.Tianjin 300052

Objective To observe neuronal apoptosis after acute brain trauma (ABT). Diffused brain trauma model was used to histologically and morphologically observe the neuronal damage by microscopy and electromicroscopy. The neuronal DNA injury in the brain cortex and hippocampus was detected by DNA-Ladder gel electrophoresis and TUNEL stain. Results After impact, the shrunken and contracted degenerations were found in neurons under microscopy. Under the electromicroscopy, para-apoptosis could be seen at the 2nd hour after impact, became the most distinct at the 24th hour and lasted 7 days. There appeared DNA-ladder electrophoresis in the hippocampus and the cortex at the 24th hour after impact through DNA-ladder gel electrophoresis. Positive TUNEL stain could be easily seen at the 2nd hour after impact, reached most distinct at the 24th hour and was still higher than normal at the 7th day. Conclusion Neuronal para-apoptosis exists in the brain tissues after ABI and can last a long time. 8 refs,2 figs.

关键词： trauma neuronal hippocampus cortex histologically ladder DNA Ladder stain appeared

Effect of transient ischemic attack on early neurological deterioration in patients with ipsilateral ischemic stroke

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China Medical Abstracts (Internal Medicine) 2018年第2期 124-124页

作者：曹杉杉 tianjin Med Univ General hosp Tianjin Neurol InstitMinistry Edu

Objective To explore the effect of anterior circulation transient ischemic attack(TIA)on early neurological deterioration(END)in patients with ipsilateral ischemic stroke and its ***(1)One hundred and thirteen patients with ipsilateral ischemic stroke and 36 healthy volunteers(healthy control group)in Neurology Department of tianjin Medical University General hospital from November 2014 to July 2015 were

关键词： TIA Effect of transient ischemic attack on early neurological deterioration in patients with ipsilateral ischemic stroke NIHSS

The treatment of severe open Pilon fractures

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外科研究与新技术 2011年第2期 111-111页

作者：曾宪铁 Dept Orthop Surg Tianjin Hosp

Objective To discuss the operative methods,timing and outcomes of severe open Pilon *** From April 2003 to July 2008,21 patients with open Pilon fractures were *** the patients were type C fracture according to

关键词： OTA open AO The treatment of severe open Pilon fractures

Therapeutic efficacy of Voriconazole on invasive fungal infections in very elderly patients

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China Medical Abstracts(Internal Medicine) 2016年第3期33卷 142-页

作者：李萌萌 Dept Geriatr Tianjin Med Univ General Hosp Tianjin Geriatr Instit

Objective To evaluate the safety and efficacy of Voriconazole on invasive fungal infections in elderly *** Clinical data of 24 elderly patients with invasive fungal infections who had sought treatment at the Department of Geriatrics of our hospital from April 2013to April 2014 were retrospectively *** classifications and quantities of fungi,accompanying symp-

关键词： very

Surgical treatment options and its results for thoracic and thoracolumbar disc herniation with or without ossification of ligment flavum

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外科研究与新技术 2011年第2期 96-96页

作者：徐宝山 Dept Spine Surg Tianjin Hosp

Objective To analyze the surgical treatment options and its results for thoracic and thoracolumbar disc *** From June 2004 to December 2009,thirty-one patients of thoracic and thoracolumbar disc herniation with

关键词： Surgical treatment options and its results for thoracic and thoracolumbar disc herniation with or without ossification of ligment flavum

The effect of atorvastatin combined with probucol on contrast-induced acute kidney injury and serum uric acid in elderly patients

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China Medical Abstracts(Internal Medicine) 2013年第1期30卷 29-29页

作者：李作成 Dept Cardiol Tianjin Chest Hosp

Objective To observe the effect of different doses of atorvastatin combined with probucol on contrast-induced acute kidney injury(CIAKI) and serum uric acid in elderly patients. Methods Totally 121 cases admitted for ... 详细信息

关键词： elderly angioplasty glomerular admitted filtration doses creatinine intake immunosorbent combi

Clinical value of nucleic acid detection for hepatitis B virus screening in hospitalized patients

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中国医学文摘:内科学分册(英文版) 2023年第2期40卷 85-85页

作者：杜春红 Dept Transfusion Med Tianjin Med Univ General HospTianjin 300052

Objective To explore clinical value of nucleic acid detection for hepatitis B virus(HBV)screening in hospitalized *** This cross-sectional study collected and analyzed plasma samples from patients admitted to 10 domes... 详细信息

关键词： patients admitted clinical

Effects of interferon regulatory factor 9 on the biological phenotypes in PML-RARα-induced promyelocytic leukemia

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China Medical Abstracts (Internal Medicine) 2022年第3期39卷 184-185页

作者：杨雪 State Key Experiment Hematol Lab Natl Clin Blood Dis Res CenterHaihe Cell Ecosystem LabTianjin Blood Dis Cell Therapy Key LabInstit Hematol & Blood Dis Hosp CAMS & PUMC

Objective To investigate the prognostic significance of interferon regulatory factor 9 (IRF9) expression and identify its role as a potential therapeutic target in acute promyelocytic leukemia (APL). Methods The gene expression profile and survival data applied in the bioinformatic analysis were obtained from The Cancer Genome Atlas and Beat acute myeloid leukemia (AML)cohorts. A dox-induced lentiviral system was used to induce the expression of PML-RARα (PR) in U937cells,and the expression level of IRF9 in U937 cells treated with or without ATRA was examined. We then induced the expression of IRF9 in NB4,a promyelocytic leukemia cell line. In vitro studies focused on leukemic phenotypes triggered by IRF9 expression.

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Study on difference between intravascular cooling system and traditional moderate hypothermia in patients with severe traumatic brain injury

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外科研究与新技术 2011年第3期 200-200页

作者：梁恩和 Dept Neurosurg Tianjin Huanhu Hosp

Objective To study difference between intravascular cooling system and traditional moderate hypothermia in patients with severe traumatic brain injury. Methods Eighty sTBI patients were randomly divided into intravascular hypothermic groups (IVT) and traditional moderate hypothermia groups(HT) . Inclusion criteria included a Glasgow Coma Scale(GCS) score ≤8 and time from injury to admission must be within 12 hours.

关键词： Study on difference between intravascular cooling system and traditional moderate hypothermia in patients with severe traumatic brain injury IVT ICP