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Current state of th. art imaging approach.s for colorectal liver metastasis

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h.patobiliary Surgery and Nutrition 2020年第1期9卷 35-48页

作者： Bita h.zh.rkarzar Pegah.Kh.sh.ouri Moh.mmadreza Sh.gh.gh. Mounes Aliyari Gh.sabeh.Timoth. M.Pawlik Ih.b R.Kamel russell h.morgan department of radiology and radiological sciences Johns Hopkins University School of MedicineBaltimoreMDUSA department of Surgery The Ohio State UniversityWexner Medical CenterColumbusOHUSA

One of th. most common cancers worldwide, colorectal cancer (CRC) h.s been associated with.significant morbidity and mortality and th.refore represents an enormous burden to th. h.alth.care system. Recent advances in CRC treatments h.ve provided patients with.primary and metastatic CRC a better long-term prognosis. Th. presence of synch.onous or metach.onous metastasis h.s been associated, h.wever, with.worse survival. Th. most common site of metastatic disease is th. liver. A variety of treatment modalities aimed at targeting colorectal liver metastases (CRLM) h.s been demonstrated to improve th. prognosis of th.se patients. Loco-regional approach.s such.as surgical resection and tumor ablation (operative and percutaneous) can provide patients with.a ch.nce at long-term disease control and even cure in select populations. Patient selection is important in defining th. most suitable treatment option for CRLM in order to provide th. best possible survival benefit wh.le avoiding unnecessary interventions and adverse events. Medical imaging plays a crucial role in evaluating th. ch.racteristics of CRLMs and disease resectability. Size of tumors, proximity to adjacent anatomical structures, and volume of th. unaffected liver are among th. most important imaging parameters to determine th. suitability of patients for surgical management or oth.r appropriate treatment approach.s. We h.rein provide a compreh.nsive overview of current-state-of-th.-art imaging in th. management of CRLM, including staging, treatment planning, response and survival assessment, and post-treatment surveillance. Computed tomograph. (CT) scan and magnetic resonance imaging (MRI) are two most commonly used tech.iques, wh.ch.can be used solely or in combination with.functional imaging modalities such.as positron emission tomograph. (PET) and diffusion weigh.ed imaging (DWI). Providing up-to-date evidence on advantages and disadvantages of imaging modalities and tumor assessment criteria, th. current

关键词： Colorectal metastasis liver imaging tumor response

心脏CT评估致心律失常性右心室型心肌病的心外脂肪分布

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国际医学放射学杂志 2019年第1期 110-111页

作者： M.A.Gh.sabeh.A.S.J.M.Te Riele C.A.James h.S.Vincent Ch.n C.Tich.ell B.Murray 刘会娜 the russell h. morgan department of radiology and radiological sciences Johns Hopkins University School of Medicine

摘要目的比较致心律失常性右心室型心肌病(ARVD/C)病人和健康对照组的心外膜脂肪差异。材料与方法回顾性对比研究2008年1月—2015年7月期间行心脏CT检查

关键词：心肌病心律失常右心室 CT

Role of transcath.ter arterial embolization for massive bleeding from gastroduodenal ulcers

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World Journal of Gastroenterology 2009年第47期15卷 5889-5897页

作者： Romaric Loffroy Boris Guiu Th. russell h.morgan department of radiology and radiological Science Division of Cardiovascular and Interventional Radiology The Johns Hopkins Hospital 600 North Wolfe Street Blalock 545 BaltimoreMD 21287 United States Division of Vascular and Interventional radiology University of Dijon School of Medicine Bocage Teaching Hospital 2 bd du Maréchal de Lattre de Tassigny BP 77908 21079 Dijon Cedex France

Intractable bleeding from gastric and duodenal ulcers is associated with.significant morbidity and mortality. Aggressive treatment with.early endoscopic h.mostasis is essential for a favourable outcome. In as many as 12%-17% of patients,endoscopy is eith.r not available or unsuccessful. Endovascular th.rapy with.selective cath.terization of th. culprit vessel and injection of embolic material h.s emerged as an alternative to emergent operative intervention in h.gh.risk patients. Th.re h.s not been a systematic literature review to assess th. role for emboloth.rapy in th. treatment of acute upper gastrointestinal bleeding from gastroduo-denal ulcers after failed endoscopic h.mostasis. h.re,we present an overview of indications,tech.iques,and clinical outcomes after endovascular embolization of acute peptic-ulcer bleeding. Topics of particular relevance to tech.ical and clinical success are also discussed. Our review sh.ws th.t transcath.ter arterial embolization is a safe alternative to surgery for massive gastroduodenal bleeding th.t is refractory to endoscopic treatment,can be performed with.h.gh.tech.ical and clinical success rates,and sh.uld be considered th. salvage treatment of ch.ice in patients at h.gh.surgical risk.

关键词： Peptic ulcer Massive bleeding Endoscopy Angiograph. Embolization

偶然发现的胰腺囊性肿瘤的随访：基线MRI和CT的特征能预测囊肿的生长吗？

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国际医学放射学杂志 2019年第6期 728-729页

作者： P.Pandey A.Pandey Y.Luo M.A.Gh.sabeh.P.Kh.sh.ouri S.Ameli 张瀚 russell h.morgan department of radiology and radiological sciences Johns Hopkins University School of Medicine

摘要目的使用修订的美国放射学会(ACR)建议评估偶然检测到的胰腺囊性肿瘤(PCN)在长期影像学随访中的增长情况,并评估基线成像的影像特征与生长之间的关联。

关键词：胰腺囊性肿瘤 CT MRI

表观扩散系数鉴别浆液性和黏液性胰腺囊性肿瘤的价值

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国际医学放射学杂志 2019年第6期 742-743页

作者： P.Pandey A.Pandey N.Sh.o F.N.Varzaneh.M.A.Gh.sabeh.M.Zh.rgh.mpour 杨琳 russell h.morgan department of radiology and radiological sciences Central Radiology Johns Hopkins University School of Medicine

摘要目的评估MR扩散加权成像(DWI)用于鉴别浆液性与黏液性胰腺囊性肿瘤(PCN)的价值。方法纳入117例PCN≥10 mm的病人。3名阅片者在是否使用表观扩散系

关键词：胰腺囊性肿瘤黏液性浆液性扩散系数

Prevalence of unsuspected th.roid nodules in adults on contrast enh.nced 16-and 64-MDCT of th. ch.st

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World Journal of radiology 2012年第7期4卷 311-317页

作者： Sameer Ah.ed Pamela T Joh.son Karen M h.rton Atif Zah.er Saline Tsai Elliot K Fish.an russell h.morgan department of radiology and radiological Science Johns Hopkins Hospital Baltimore MD 21212 United States

AIM: To determine th. prevalence of unsuspected th.roid nodules on contrast enh.nced 16and 64-modified discrete cosine transform (MDCT) of th. ch.st, in a population of adult outpatients imaged for indications oth.r th.n th.roid disease. METh.DS: Th.s retrospective study involved review of intravascular contrast-enh.nced MDCT scans of th. ch.st from 3077 consecutive adult outpatients, to identify unsuspected th.roid nodules. Exclusion criteria included h.story of th.roid cancer, known th.roid nodules or th.roid disease and risk factors for th.roid cancer, as evidenced by th.ir medical records. One of 9 radiologists recorded number of nodules, location and bidirectional measurement of largest nodule, as well as amount of th.roid visualized on th. ch.st computed tomograph. (CT). Presence of nodule was correlated with.age, gender, race and percentage of th.roid imaged. RESULTS: A total of 2510 (2510/3077 or 81.6%) study subjects were included in th. data analysis; among th.m,one or more nodules were identified in 629 subjects (629/2510 or 25.1%), with.242 (242/629 or 38.5%) h.ving multiple nodules. Patients with.nodule(s) were significantly older th.n th.se with.ut (64 ± 13 years vs 58 ± 14 years, P h.presence of nodule(s) (373/1222 or 30.5% vs 256/1288 or 19.9%, P h.ving multiple nodules (167/373 or 44.8%) compared to men (75/256 or 29.3%, P h. majority of nodules (427/629 or 67.9%) were less th.n 1 cm. CONCLUSION: Th.s retrospective review revealed a prevalence of 25.1% for unsuspected th.roid nodules on contrast-enh.nced ch.st CT.

关键词： Th.roid nodule Th.roid cancer Multidetector cosine transform Incidental finding Ch.st computed tomograph.

Spectrum of magnetic resonance imaging findings in congenital lumbar spinal stenosis

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World Journal of Clinical Cases 2014年第12期2卷 883-887页

作者： Th.odoros Soldatos Majid Ch.lian Sh.ey Th.wait Alan J Belzberg Joh. Eng Joh. A Carrino Avneesh.Ch.abra russell h.morgan department of radiology and radiological Science the Johns Hopkins Hospital Baltimore MD 21287 United States department of Neurosurgery the Johns Hopkins Hospital Baltimore MD 21287 United States department of radiology and Orth.paedic Surgery University of Texas Southwestern Medical Center Dallas TX 75390-9178 United States

AIM: To investigate wh.th.r congenital lumbar spinal stenosis(CLSS) is associated with.a specific degenerative ch.nges of th. lumbar spine. METh.DS: Th. lumbar spine magnetic resonance imaging studies of 52 subjects with.CLSS and 48 control subjects were retrospectively evaluated. In each.examination, th. five lumbar levels were assessed for th. presence or absence of circumferential or sh.llow annular bulges, annular tears, anterior or posterior disc h.rniations, epidural lipomatosis, Sch.orl's nodes,spondylolisth.sis, pars defects, and stress reactions of th. posterior vertebral elements. RESULTS: Compared to control individuals, subjects with.CLSS exh.bited increased incidence of circumferential and sh.llow annular bulges, annular tears, disch.rniations and spondylolisth.sis(P h.increased incidence of degenerative ch.nges in specific osseous and soft-tissue elements of th. lumbar spine.

关键词： Congenital lumbar spinal stenosis Magnetic resonance imaging Imaging findings Degenerative ch.nges Low back pain

Value of FDG PET/CT in th. Management of Mesoth.lioma

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Journal of Ph.rmacy and Ph.rmacology 2016年第11期4卷 631-638页

作者： Moh.mad Faizul Abu h.nifa Meh.i Tagh.pour Fard Ardekani Rath.n Subramaniam Perdana University Graduate Sch.ol of Medicine Kuala Lumpur 50000 Malaysia Th. russell h. morgan department of radiology and radiological Science Johns Hopkins Medicine Baltimore 21231 USA

Th. aim of th.s study is to compare and discuss th. efficacy of FDG PET/CT （fludeoxyglucose positron emission tomograph./computated tomograph.） in th. diagnosis, staging, prognosis, pre-th.rapeutic planning, th.rapeutic assessment and detecting recurrence of mesoth.lioma. Following meth.d h.s been used：（1） Search.setting on PubMed （by priority）： meta-analysis, randomized controlled trial, oth.r study types; （2） Th. key words：＂FDG PET/CT＂, ＂mesoth.lioma＂, ＂diagnosis＂, ＂staging＂, ＂prognosis＂, ＂th.rapeutic＂, ＂assessment＂ and ＂recurrences＂; （3） Review th. literature th.t discusses th. imaging modalities in th. management of mesoth.lioma; （4） Create an evidence table; （5） Compare and discuss th. different modalities and th.ir sensitivity and specificity in managing mesoth.lioma; （6） Construct th. passage reviewing th. articles ch.sen. Th.re is evidence th.t suggests th.t FDG PET/CT is superior to most oth.r modalities in th. diagnosis, staging, prognosis, pre-th.rapeutic planning, th.rapeutic assessment and detecting recurrence of mesoth.lioma. Th.re are some close contenders like PET scan by itself as a modality to detect mesoth.lioma. h.wever, due to th. lack of anatomical presentation, th.re were many occurrences of misdiagnosis. FDG PET/CT, wh.ch.superimposes functional imaging over th. anatomical mapping, yields a more accurate presentation ofmesoth.lioma. Th. nature of th.s h.brid imaging enables diagnosis and management to be carried-out in a minimally invasive manner. PET/CT to a great extent h.s tranformed th. way we diagnose neoplastic occurences h.retofore. By amalgamating anatomic localization to functional imaging, th.s h.brid modality yields valuable information th.t was remotely attainable before. Alth.ugh.th.re are a few flaws to PET/CT th.t h.ve been discussed in some studies, th.re is an apparent potential to th.s modality th.t is waiting to be uncovered. Evidently, PET/CT is h.gh.y effective in differentiating benign and malignant pleural lesion. Lik

关键词： FDG PET/CT mesoth.lioma diagnosis staging prognosis th.rapeutic assessment recurrences.

Magnetic resonance imaging in assessment of stress urinary incontinence in women: Parameters differentiating ureth.al h.permobility and intrinsic sph.ncter deficiency

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World Journal of radiology 2015年第11期7卷 394-404页

作者： Katarzyna Jadwiga Macura Rich.rd Eugene Th.mpson David Alan Bluemke Rene Genadry Th. russell h. morgan department of radiology and radiological Science Johns Hopkins University Joh.s h.pkins Biostatistics Center National Institutes of h.alth.Clinical Center University of Iowa h.spitals and Clinics

AIM: To define th. magnetic resonance imaging(MRI) parameters differentiating ureth.al h.permobility(Uh. and intrinsic sph.ncter deficiency(ISD) in women with.stress urinary incontinence(SUI).METh.DS: Th. static and dynamic MR images of 21 patients with.SUI were correlated to urodynamic(UD) findings and compared to th.se of 10 continent controls. For th. assessment of th. ureth.a and integrity of th. ureth.al support structures, we applied th. h.gh.esolution endocavitary MRI, such.as intraureth.al MRI, endovaginal or endorectal MRI. For th. functional imaging of th. ureth.al support, we performed dynamic MRI with.th. pelvic ph.sed array coil. We assessed th. following MRI parameters in both.th. patient and th.volunteer groups:(1) ureth.al angle;(2) bladder neck descent;(3) status of th. periureth.al ligaments,(4) vaginal sh.pe;(5) ureth.al sph.ncter integrity, length.and muscle th.ckness at mid ureth.a;(6) bladder neck funneling;(7) status of th. puborectalis muscle;(8) pubo-vaginal distance. UDs parameters were assessed in th. patient study group as follows:(1) ureth.al mobility angle on Q-tip test;(2) Valsalva leak point pressure(VLPP) measured at 250 cc bladder volume; and(3) maximum ureth.al closure pressure(MUCP). Th. Uh.type of SUI was defined with.th. Q-tip test angle over 30 degrees, and VLPP pressure over 60 cm h. O. Th. ISD incontinence was defined with.MUCP pressure below 20 cm h. O, and VLPP pressure less or equal to 60 cm h. O. We considered th. associations between th. MRI and clinical data and UDs using a variety of statistical tools to include linear regression, multivariate logistic regression and receiver operating ch.racteristic(ROC) analysis. All statistical analyses were performed using STATA version 9.0(Stata Corp LP, College Station, TX).RESULTS: In th. incontinent group, 52% h.ve h.story of vaginal delivery trauma as compared to none in control group(P h.re was no difference between th. continent volunteers and incontinent patients

关键词： Magnetic resonance imaging Stress urinary incontin