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Neural Regeneration Research 2025年第11期20卷 3217-3218页

作者： Laura Huggon Emma L.Clayton UK Dementia Research Institute at king’s College London LondonUK Department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T D)and amyo t rophic lateral sclerosis(ALs)are neurodegenerative diseases with significant overlapping *** these neurodegenerative diseases affect different neuronal populations(with FTD affecting neurons of the frontal and temporal lobes,and ALs affecting upper and lower motor neurons),these two diseases are complexly *** and ALs exist on a disease spectrum,with shared genetic causes,clinical presentations,and pathologies.

关键词： diseases amyotrophic sclerosis

Recoil polarimetry with the Crystal Ball at MAMI

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Chinese Physics C 2009年第12期33卷 1183-1188页

作者： D.P. Watts D.I. Glazier M.s. sikora University of Edinburgh King's Buildings Edinburgh EH9 3JZ UK

The spectrum and properties of the excited states of the nucleon are still poorly established despite decades of study. These proceedings describe new measurements of pseudo-scalar meson photoproduction at the Crystal Ball at MAMI, employing a new large acceptance nucleon recoil polarimeter. The double- and single-polarisation observables obtained will provide valuable and unique data to be used as part of the world effort to improve our knowledge of this fundamental spectrum.

关键词： photoproduction reactrons

Exploring Nanoscale Perovskite Materials for Next‑Generation Photodetectors:A Comprehensive Review and Future Directions

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Nano-Micro Letters 2025年第2期17卷 46-108页

作者： Xin Li sikandar Aftab Maria Mukhtar Fahmid Kabir Muhammad Farooq Khan Hosameldin Helmy Hegazy Erdi Akman state Key Laboratory of Pulsed Power Laser Technology National University of Defense TechnologyHefei 230037AnhuiPeople’s Republic of China Anhui Laboratory of Advanced Laser Technology Hefei 230037AnhuiPeople’s Republic of China Nanhu Laser Laboratory Changsha 410015HunanPeople’s Republic of China Department of semiconductor systems Engineering and Clean Energy Sejong UniversitySeoul 05006Republic of Korea Department of Artificial Intelligence and Robotics Sejong UniversitySeoul 05006Republic of Korea school of Engineering science Simon Fraser UniversityBurnabyBC V5A 1S6Canada Department of Electrical Engineering Sejong UniversitySeoul 05006South Korea Department of Physics Faculty of ScienceKing Khalid UniversityP.O.Box 9004AbhaSaudi Arabia Central Labs King Khalid UniversityAlQura’aP.O.Box 96061413 AbhaSaudi Arabia scientific and Technological Research and Application Center Karamanoglu Mehmetbey University70100 KaramanTurkey

The rapid advancement of nanotechnology has sparked much interest in applying nanoscale perovskite materials for photodetection *** materials are promising candidates for next-generation photodetectors(PDs)due to their unique optoelectronic properties and flexible synthesis *** review explores the approaches used in the development and use of optoelectronic devices made of different nanoscale perovskite architectures,including quantum dots,nanosheets,nanorods,nanowires,and *** a thorough analysis of recent literature,the review also addresses common issues like the mechanisms underlying the degradation of perovskite PDs and offers perspectives on potential solutions to improve stability and scalability that impede widespread *** addition,it highlights that photodetection encompasses the detection of light fields in dimensions other than light intensity and suggests potential avenues for future research to overcome these obstacles and fully realize the potential of nanoscale perovskite materials in state-of-the-art photodetection *** review provides a comprehensive overview of nanoscale perovskite PDs and guides future research efforts towards improved performance and wider applicability,making it a valuable resource for researchers.

关键词： Nanoscale perovskites Photodetectors Nanosheets Nanorods Nanowires Quantum dots Nanocrystals

EQUIVARIANT COHOMOLOGY AND REPREsENTATIONs OF THE sYMMETRIC GROUP

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Chinese Annals of Mathematics,series B 2001年第1期22卷 23-30页

作者： M. ATIYAH Department of Mathematics & statistics University of Edinburgh James Clerk Maxwell Buildings King's Buildings Edinburgh EH9 3JZ UK

In a recent paper the author constructed a continuous map from the configuration space of n distinct ordered points in 3-space to the flag manifold of the unitary group U(n), which is compatible with the action of the symmetric group. This map is also compatible with appropriate actions of the rotation group sO(3). In this paper the author studies the induced homomorphism in sO(3)-equivariant cohomology and shows that this contains much interesting information involving representations of the symmetric group.

关键词： Cohomology symmetric group Rotation group

Recoil polarimetry in meson photoproduction at MAMI

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Chinese Physics C 2009年第12期33卷 1373-1376页

作者： M.H. sikora D.I. Glazier D.P. Watts University of Edinburgh King’s Buildings Edinburgh EH9 3JZ United Kingdom

The nucleon excitation spectrum remains poorly known, with the masses, widths, EM couplings and even existence of many states not well established. A program of experiments using meson photoproduction off the nucleon is being carried out to improve this situation. A new large acceptance recoil polarimeter has been developed by the Edinburgh group for use in such reactions with the Crystal Ball at MAMI. This work summarizes the procedure used to measure recoil polarization with the new device and presents some preliminary results for the double polarization observable Cx in the reaction γp→pπ, compared to the current partial wave analysis.

关键词： polarimeter meson photoproduction polarization observable recoil

CFD simulation of fluidization quality in the three-dimensional fluidized bed

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Progress in Natural science:Materials International 2008年第6期18卷 729-733页

作者： stefano Brandani Edinburgh EH9 3JL IMP-sEE University of Edinburgh the king’s buildings UK

Multiphase computational fluid dynamics(CFD)has become an alternative method to experimental investigation for predicting the fluid dynamics in gas-solid fluidized *** model of Brandani and Zhang,which contains additional terms in both the gas-and solid-phase momentum equations,is employed to explore homogeneous fluidization of Geldart type A particles and bubbling fluidization of Geldart type B particles in three-dimensional gas-fluidized *** this model,only a correlation for drag force is necessary to close the governing *** kinds of solids,i.e.,fine alumina powder(dp=60 lm and qp=1500 kg/m3)and sand(dp=610 lm and qp=2500 kg/m3),are numerically simulated in a rectangular duct of 0.2 m(long)0.2 m(wide)0.5 m(high)*** results show good agreement with the classic theory of Geldart.

关键词： Three-dimensional gas-solid fluidized bed Fluidization quality CFD simulation

A general method for assaying homo-and hetero-transglycanase activities that act on plant cell-wall polysaccharides

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Journal of Integrative Plant Biology 2015年第4期57卷 411-428页

作者： Lenka Franková stephen C.Fry The Edinburgh Cell Wall Group Institute of Molecular Plant SciencesThe University of EdinburghDaniel Rutherford BuildingThe King's Buildings

Transglycanases（endotransglycosylases） cleave a polysaccharide（donor-substrate） in mid-chain, and then transfer a portion onto another poly-or oligosaccharide（acceptor-substrate）. such enzymes contribute to plant cellwall assembly and/or re-structuring. We sought a general method for revealing novel homo- and hetero-transglycanases, applicable to diverse polysaccharides and oligosaccharides, separating transglycanase-generated3 Hpolysaccharides from unreacted3H-oligosaccharides—the former immobilized（on filter-paper, silica-gel or glassfiber）,the latter eluted. On filter-paper, certain polysaccharides [e.g.（1!3, 1!4）-b-D-glucans] remained satisfactorily adsorbed when water-washed; others（e.g. pectins） were partially lost. Many oligosaccharides（e.g. arabinan-, galactan-, xyloglucan-based） were successfully eluted in appropriate solvents, but others（e.g. [3H]xylohexaitol, [3H]mannohexaitol[3H]cellohexaitol） remained immobile. On silica-gel, all3 Holigosaccharides left an immobile ‘ghost’ spot（contaminating any3H-polysaccharides）, which was diminished but not prevented by additives e.g. sucrose or Triton X-100. The best stratum was glassfiber（GF）, onto which the reactionmixture was dried then washed in 75% ethanol. Washing led to minimal loss or lateral migration of3H-polysaccharides if conducted by slow percolation of acidified ethanol. The effectiveness of GF-blotting was well demonstrated for Chara vulgaris transb-mannanase. In conclusion, our novel GF-blotting technique ef ficiently frees transglycanase-generated3H-polysaccharides from unreacted3H-oligosaccharides,enabling high-throughput screening of multiple postulated transglycanase activities utilising chemically diverse donorand acceptor-substrates.

关键词： Glass-fiber blotting plant cell wall polysaccharides(donor) radiolabeled oligosaccharides (acceptor) transglycanase

Decoding molecular mechanisms:brain aging and Alzheimer's disease

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Neural Regeneration Research 2025年第8期20卷 2279-2299页

作者： Mahnoor Hayat Rafay Ali syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna Abdullah Mohammed Albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish sBhatti shahid Bashir Atta-ur-Rahman school of Applied Biosciences(AsAB) National University of Sciences and Technology(NUST)IslamabadPakistan Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan Department of Biological sciences Faculty of Basic&Applied SciencesInternational Islamic University Islamabad(IIUI)IslamabadPakistan Department of Bioengineering King Fahd University of Petroleum and MineralsDhahranSaudi Arabia Department of Physiology College of MedicineKing Saud UniversityRiyadhSaudi Arabia Department of Neurology Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Mental Health Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Biosciences Commission on Science and Technology for Sustainable Development in the South(COMSATS University)IslamabadPakistan Department of Psychiatry The First Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Mental Health Institute of Hebei Medical University ShijiazhuangHebei ProvinceChina Department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA Neuroscience Center King Fahad Specialist Hospital DammamDammamSaudi Arabia

The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for *** aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's *** these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging *** these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect *** review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.

关键词： Alzheimer’s disease brain aging cognitive health dementia molecular mechanisms neuronal activity neuroplasticity neurotransmission

There is no such thing as the ‘Ediacara Biota'

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Geoscience Frontiers 2014年第1期5卷 53-62页

作者： Breandán Anraoi MacGabhann school of Geosciences University of Edinburgh King’s Buildings West Mains RoadEdinburgh EH9 3JW UK

The term ＇Ediacara Biota＇（or many variants thereof） is commonly used to refer to certain megascopic fossils of Precambrian and early Palaeozoic age - but what does the term actually mean？ What differ- entiates a non-Ediacaran ＇Ediacaran＇ and an Ediacaran ＇Ediacaran＇ from an Ediacaran non-＇Ediacaran＇？ Historically, the term has been used in either a geographic, stratigraphic, taphonomic, or biologic sense. More recent research and new discoveries, however, mean that the term cannot actually be defined on any of these bases, or any combination thereof. Indeed, the term is now used and understood in a manner which is internally inconsistent, and unintentionally implies that these fossils are somehow distinct from other fossil assemblages, which is simply not the case. Continued use of the term is a historical relic, which has led in part to incorrect assumptions that the ＇Ediacara Biota＇ can be treated as a single coherent group, has obscured our understanding of the biological change over the Precambrian-Cambrian boundary, and has confused research on the early evolution of the Metazoa. In the future, the term ＇Ediacaran＇ should be restricted to purely stratigraphic usage, regardless of affinity, geography, or taphonomy; sufficient terminology also exists where reference to specimens on a geographic, tapho- nomic, or biologic basis is required. It is therefore time to abandon the term ＇Ediacara Biota＇ and to instead treat ecmallv all of the fossils of the Ediacaran system.

关键词： Ediacara Biota Ediacaran Cambrian Metazoan evolution Terminal Precambrian mass extinction

Enhancing Deepfake Detection:Proactive Forensics Techniques Using Digital Watermarking

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Computers, Materials & Continua 2025年第1期82卷 73-102页

作者： Zhimao Lai saad Arif Cong Feng Guangjun Liao Chuntao Wang school of Automation Guangdong University and TechnologyGuangzhou510006China school of Immigration Administration(Guangzhou) China People’s Police UniversityGuangzhou510663China Department of Mechanical Engineering College of EngineeringKing Faisal UniversityAl Ahsa31982Saudi Arabia Cyber Police Division Guangzhou Public Security BureauGuangzhou510030China school of Forensic science and Technology Guangdong Police CollegeGuangzhou510320China College of Mathematics and Informatics South China Agricultural UniversityGuangzhou510642China

With the rapid advancement of visual generative models such as Generative Adversarial Networks(GANs)and stable Diffusion,the creation of highly realistic Deepfake through automated forgery has significantly *** paper examines the advancements inDeepfake detection and defense technologies,emphasizing the shift from passive detection methods to proactive digital watermarking *** detection methods,which involve extracting features from images or videos to identify forgeries,encounter challenges such as poor performance against unknown manipulation techniques and susceptibility to counter-forensic *** contrast,proactive digital watermarking techniques embed specificmarkers into images or videos,facilitating real-time detection and traceability,thereby providing a preemptive defense againstDeepfake *** offer a comprehensive analysis of digitalwatermarking-based forensic techniques,discussing their advantages over passivemethods and highlighting four key benefits:real-time detection,embedded defense,resistance to tampering,and provision of legal ***,the paper identifies gaps in the literature concerning proactive forensic techniques and suggests future research directions,including cross-domain watermarking and adaptive watermarking *** systematically classifying and comparing existing techniques,this review aims to contribute valuable insights for the development of more effective proactive defense strategies in Deepfake forensics.

关键词： Deepfake proactive forensics digital watermarking traceability detection techniques