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The Relationship Between the Atmospheric Environment and Road Traffic Fatalities — Shandong Province, China, 2012–2021

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China CDC weekly 2024年第13期6卷 267-271页

作者： Tao Wang Jie Chu Zhiying Yao Li Yang Zilong Lu Ge Tian Xiaolei Guo Cunxian Jia department of epidemiology School of Public HealthCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina department for Chronic and Non-Communicable Disease Control and prevention Shandong Center for Disease Control and PreventionJinanShandong ProvinceChina

Introduction:This study aims to analyze the potential impact of the meteorological environment and air pollutants on road traffic ***:Road traffic fatality data in Shandong Province from 2012 to 2021 were obtained from the Population Death Information Registration Management *** and air pollutant data for the same period were collected from the *** Oceanic and Atmospheric Administration and the Ecological Environment Monitoring Center of Shandong Province,***’s correlation and ridge regression were used to analyze the impact of the meteorological environment and air pollutants on road traffic ***:From 2012 to 2021,there were 163,863 road traffic fatality *** results of the ridge regression analysis showed that the daily average temperature was negatively correlated with total fatalities and passengers and positively correlated with pedestrians,nonmotorized drivers,and motorized *** daily minimum temperature was negatively correlated with total fatalities and positively correlated with motorized *** daily maximum temperature was positively correlated with both pedestrian and nonmotorized *** daily accumulated precipitation was negatively correlated with *** duration was positively correlated with both nonmotorized and motorized *** particulate matter(PM_(10))and nitrogen dioxide(NO_(2))were positively correlated with total fatalities,pedestrians,and nonmotorized *** dioxide(SO_(2))was positively correlated with total fatalities but negatively correlated with nonmotorized drivers,passengers,and motorized ***:Atmospheric factors associated with the occurrence of road traffic fatalities include air temperature,daily accumulated precipitation,sunshine duration,and air pollutants such as PM_(10),NO_(2),and SO_(2).

关键词： Ecological dioxide sunshine

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The non-stationary and spatially varying associations between hand,foot and mouth disease and multiple environmental factors:A Bayesian spatiotemporal mapping model study

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Infectious Disease Modelling 2024年第2期9卷 373-386页

作者： Li Shen Minghao Sun Mengna Wei Qingwu Hu Yao Bai Zhongjun Shao Kun Liu School of Remote Sensing and Information Engineering Wuhan UniversityWuhanHubei ProvinceChina department of infection Disease Control and prevention Xi'an Center for Disease Control and PreventionXi'anShaanxiChina department of epidemiology Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational EnvironmentSchool of Public HealthAir Force Medical UniversityXi'anShaanxi ProvinceChina

The transmission and prevalence of Hand,Foot and Mouth Disease(HFMD)are affected by a variety of natural and socio-economic environmental *** study aims to quantitatively investigate the non-stationary and spatially varying associations between various environmental factors and HFMD *** collected HFMD surveillance cases and a series of relevant environmental data from 2013 to 2021 in Xi'an,Northwest *** controlling the spatial and temporal mixture effects of HFMD,we constructed a Bayesian spatiotemporal mapping model and characterized the impacts of different driving factors into global linear,non-stationary and spatially varying *** results showed that the impact of meteorological conditions on HFMD risk varies in both type and magnitude above certain thresholds(temperature:30°C,precipitation:70 mm,solar radiation:13000 kJ/m^(2),pressure:945 hPa,humidity:69%).Air pollutants(PM_(2.5),PM_(10),NO_(2))showed an inverted U-shaped relationship with the risk of HFMD,while other air pollutants(O_(3),SO_(2))showed nonlinear ***,the driving effect of increasing temperature on HFMD was significant in the 3-year period,while the inhibitory effect of increasing precipitation appeared evident in the 5-year *** addition,the proportion of urban/suburban/rural area had a strong influence on HFMD,indicating that the incidence of HFMD firstly increased and then decreased during the rapid urbanization *** influence of population density on HFMD was not only limited by spatial location,but also varied between high and low *** road density inhibited the risk of HFMD,but higher night light index promoted the occurrence of *** findings further demonstrated that both ecological and socioeconomic environmental factors can pose multiple driving effects on increasing the spatiotemporal risk of HFMD,which is of great significance for effectively responding to the changes in HFMD epidemic outbreaks.

关键词： Hand,foot,and mouth disease(HFMD) Environmental factors Bayesian spatiotemporal mapping model Non-stationary effects Spatially varying effects

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An Outbreak of Serogroup Y Meningococcal Meningitis in a Private Secondary Vocational School-Guangzhou City,Guangdong Province,China,2023

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China CDC weekly 2024年第12期6卷 242-246,I0005页

作者： Xiang Zeng Qing He Yilan Li Yong Zhou Xiaoping Shao Pei Hu Jian Liang Yudan Song Chao Ma Lijie Zhang Limei Sun Lei Luo Chinese Field epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina Zhuhai Center for Disease Control and prevention Zhuhai CityGuangdong ProvinceChina Guangdong Center for Disease Control and prevention Guangzhou CityGuangdong ProvinceChina Guangzhou Center for Disease Control and prevention Guangzhou CityGuangdong ProvinceChina Institute of Public Health Guangzhou Medical University&Guangzhou Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina department of the National Immunization Programme Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?The inclusion of meningococcal vaccines in the National Immunization Program(NIP)over several years has significantly reduced the incidence of meningococcal meningitis in China to historic ***,there has been a diversification of meningococcal serogroups,leading to a shift in dominant serogroups in China from serogroup A to serogroups C and B,accompanied by a rise in reports of serogroups Y and *** is added by this report?An outbreak of serogroup Y Neisseria meningitidis(Nm)in a secondary vocational school involved a single confirmed severe case and 24 individuals with laboratory-confirmed Nm *** investigation revealed that the outbreak was localized to the classroom of the confirmed *** close contact within a confined space was identified as a significant risk factor for Nm *** genotype sequence identified was type 1655(ST-1655),which is categorized under clonal complex 23(CC-23)and bears resemblance to 8 previously confirmed cases of serogroup Y meningococcal meningitis within Guangdong *** suggests that serogroup Y infections continue to sporadically emerge and have become prevalent *** are the implications for public health practice?This outbreak underscores the critical need to enhance surveillance of meningococcal serogroups and population carrier,and advocate for vaccination with MenY-containing vaccines.

关键词： break Secondary Guangdong

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Salmonella Grumpensis Causing Diarrhea in Children—Shanghai Municipality,China,2023

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China CDC weekly 2024年第18期6卷 396-400,I0006,I0007页

作者： Yue Liu Xuebin Xu Wenqin Wang Wenjia Xiao Yi Hu Xin Chen Min Chen Shanghai Municipal Center for Disease Control and prevention ShanghaiChina Pudong New Area Center for Disease Control and prevention ShanghaiChina department of epidemiology Key Laboratory of Public Health Safety of Ministry of EducationSchool of Public HealthFudan UniversityShanghaiChina

Summary What is already known about this topic?Foodborne diseases are a growing public health concern with a notable disease burden in *** is added by this report?Two children with diarrhea visited a healthcare facility within 24 hours on August 1 and 2,*** Grumpensis was detected in their stool samples by the public health *** genome sequencing(WGS)analysis revealed characteristics typical of outbreak *** the origin of the outbreak was unknown,the possibility of a hidden shared infection was deemed feasible.

关键词： diarrhea diseases Whole

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The Association Between Depression and All-Cause,Cause-Specific Mortality in the Chinese Population—China,2010-2022

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China CDC weekly 2024年第40期6卷 1022-1027页

作者： Jifei Wang Zhenping Zhao Jing Yang Limin Wang Mei Zhang Maigeng Zhou department of epidemiology School of Public HealthCheeloo College of MedicineShandong UniversityJinan CityShandong ProvinceChina National Center for Chronic and Noncommunicable Disease Control and prevention Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?Depression is linked to higher all-cause and cardiovascular mortality rates,but its effects on specific subgroups and non-cardiovascular mortality in the Chinese population remain *** is added by this report?Both severe and mild to moderate depression were found to elevate mortality rates among the Chinese *** impact was particularly notable among males,urban residents,younger individuals,and those with higher education *** exhibited a stronger connection with fatalities related to suicide and non-suicidal *** are the implications for public health practice?Individuals experiencing mild depression require healthcare attention to avoid negative *** physical and psychological support is particularly crucial for high-risk subgroups.

关键词： mortality injuries cardiovascular

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Effectiveness of colorectal cancer screening integrating non-genetic and genetic risk: a prospective study based on UK Biobank data

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Cancer Biology & Medicine 2024年第8期21卷 712-723页

作者： Yu Zhang Chao Sheng Zhangyan Lyu Hongji Dai Fangfang Song Fengju Song Yubei Huang Kexin Chen department of epidemiology and Biostatistics Key Laboratory of Molecular Cancer EpidemiologyKey Laboratory of Prevention and Control of Human Major DiseasesMinistry of EducationNational Clinical Research Center for CancerTianjin Medical University Cancer Institute and HospitalTianjin Medical UniversityTianjin 300060China

Objective: Few studies have evaluated the benefits of colorectal cancer(CRC) screening integrating both non-genetic and genetic risk factors. Here, we aimed to integrate an existing non-genetic risk model(QCancer-10) and a 139-variant polygenic risk score to evaluate the effectiveness of screening on CRC incidence and ***: We applied the integrated model to calculate 10-year CRC risk for 430,908 participants in the UK Biobank, and divided the participants into low-, intermediate-, and high-risk groups. We calculated the screening-associated hazard ratios(HRs) and absolute risk reductions(ARRs) for CRC incidence and mortality according to risk ***: During a median follow-up of 11.03 years and 12.60 years, we observed 5,158 CRC cases and 1,487 CRC deaths, respectively. CRC incidence and mortality were significantly lower among screened than non-screened participants in both the intermediateand high-risk groups [incidence: HR: 0.87, 95% confidence interval(CI): 0.81±0.94;0.81, 0.73±0.90;mortality: 0.75, 0.64±0.87;0.70, 0.58±0.85], which composed approximately 60% of the study population. The ARRs(95% CI) were 0.17(0.11±0.24) and 0.43(0.24±0.61), respectively, for CRC incidence, and 0.08(0.05±0.11) and 0.24(0.15±0.33), respectively, for mortality. Screening did not significantly reduce the relative or absolute risk of CRC incidence and mortality in the low-risk group. Further analysis revealed that screening was most effective for men and individuals with distal CRC among the intermediate to high-risk ***: After integrating both genetic and non-genetic factors, our findings provided priority evidence of risk-stratified CRC screening and valuable insights for the rational allocation of health resources.

关键词： Colorectal cancer screening polygenic risk score incidence mortality

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Establishment and Application of a Radiation Dose Rate Model for Nuclear Medicine Examinees

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China CDC weekly 2024年第23期6卷 553-557,I0019-I0025页

作者： Yuehua Hu Xinyu He Wenjia Zhao Lixin Ding Meiying You Zihan Li Xinyu Liu Miaomiao Wang Siyi Chen Ziwei Lu Lei Qu Kuke Ding Li Zhang Qiuxian Fu Office of epidemiology Chinese Center for Disease Control and PreventionBeijingChina department of Oncology Central Hospital Affiliated to Shandong First Medical UniversityJinan CityShandong ProvinceChina National Institute for Radiological Protection Chinese Center for Disease Control and PreventionBeijingChina National Center for Chronic and Noncommunicable Disease Control and prevention Chinese Center for Disease Control and PreventionBeijingChina Laboratory Animal Center Chinese Center for Disease Control and PreventionBeijingChina National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghaiChina Office of Public Health Management Chinese Center for Disease Control and PreventionBeijingChina Hainan Medical University Haikou CityHainan ProvinceChina

Introduction:Traditional methods for determining radiation dose in nuclear medicine include the Monte Carlo method,the discrete ordinate method,and the point kernel integration *** study presents a new mathematical model for predicting the radiation dose rate in the vicinity of nuclear medicine ***:A new algorithm was created by combining the physical model of“cylinder superposition”of the human body with integral analysis to assess the radiation dose rate in the vicinity of nuclear medicine ***:The model accurately predicted radiation dose rates within distances of 0.1–3.0 m,with a deviation of less than 11%compared to observed *** model demonstrated greater accuracy at shorter distances from the radiation source,with a deviation of only 1.55%from observed values at 0.1 ***:The model proposed in this study effectively represents the spatial and temporal distribution of the radiation field around nuclear medicine patients and demonstrates good agreement with actual *** model has the potential to serve as a radiation dose rate alert system in hospital environments.

关键词： method. deviation cylinder

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Trends and Spatial Pattern Analysis of Typhoid and Paratyphoid Fever Incidence — Yunnan Province, China, 1989–2022

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China CDC weekly 2024年第41期6卷 1049-1053,I0001,I0002页

作者： Xiulian Shen Liqiong Zhang Lining Guo Jibo He Weijun Yu Epidemic Surveillance/Public Health Emergency Response Center Yunnan Provincial Center for Disease Control and PreventionKunming CityYunnan ProvinceChina department of Intervention Research Yunnan Institute for Drug AbuseKunming CityYunnan ProvinceChina Hunnan District Center for Disease Control and prevention Shenyang CityLiaoning ProvinceChina Institute for prevention and Control of infection and Infectious Diseases Liaoning Provincial Center for Disease Control and PreventionShenyang CityLiaoning ProvinceChina.

Introduction:This study explored the incidence trends and spatial clustering of typhoid and paratyphoid fever(TPF)in Yunnan Province to provide scientific evidence for developing and improving prevention and control ***:Temporal trends were investigated by calculating the annual percent change(APC)and average annual percent change(AAPC),along with their 95%confidence intervals(CIs).The spatial clustering of TPF across Yunnan Province was examined using global Moran’s I and local indicators of spatial association(LISA)***:A total of 206,066 TPF cases were reported in Yunnan Province from 1989 to 2022,with an average annual incidence of 13.98 per 100,000 population and a case fatality rate of 2.5 per 1,*** greatest number of cases was reported during July and *** 25–34-year age group had the highest incidence,and farmers were prominently *** incidence in Yunnan Province showed a significant decrease and spatial *** 2005 to 2022,13 county-level cities/counties/municipal districts in 5 prefectures(cities)in Yunnan Province were identified as statistically significant H-H spatial clusters of TPF incidence.A total of 24 TPF outbreaks were reported in Yunnan Province from 2005 to ***:The incidence of TPF in Yunnan Province showed a significant decrease and spatial *** strategies should focus on highincidence areas,seasons,and populations to reduce the incidence of TPF.

关键词： Spatial prevention district

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First Case Report of Cystic Echinococcosis Caused by G7 Genotype Echinococcus intermedius Confirmed by Genetic Sequencing—Southern China,December 2023

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China CDC weekly 2024年第23期6卷 558-562页

作者： De Wu Jiayi Zhang Jieling Wang Yangyang Zhao Lei Wang Qiang Mao Haisen Lin Gang Yao Guanting Zhang Xu Wang Chuizhao Xue Ying Wang Jingdiao Chen Parasitic Disease prevention and Control Institute Guangdong Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina Epidemic prevention and Control Institute Zhuhai Center for Disease Control and PreventionZhuhai CityGuangdong ProvinceChina department of prevention&Healthcare Zhuhai First People's HospitalZhuhai CityGuangdong ProvinceChina National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)ShanghaiChina

What is already known about this topic?Echinococcosis exhibits a global *** China,the primary endemic area is the northwest *** December 2023,we documented a case of echinococcosis in an individual lacking any travel or residential history in endemic *** is added by this report?This is the first laboratory-confirmed case of hepatic echinococcosis reported in Guangdong Province,associated with the G7 genotype of Echinococcus granulosus(***).The most probable mode of transmission is a local infection resulting from *** introduced from endemic *** are the implications for public health practice?As the circulation of agricultural products increases,it is essential to enhance the quarantine and management of livestock from epidemic areas to prevent and control the spread of echinococcosis to non-epidemic regions.

关键词： travel fir northwest

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Evaluation of Latent Tuberculosis infection Using the ESAT6-CFP10 Skin Test Among International Freshmen With Diverse Skin Tones at a University—Nanjing City,Jiangsu Province,China,September 2023

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China CDC weekly 2024年第35期6卷 896-900,I0001页

作者： Peng Lu Rong Wang Jingjing Xu Jianming Wang Fangfang Du Guozhi Wang Shiming Cheng Limei Zhu department of Chronic Communicable Disease Jiangsu Provincial Center for Disease Control and PreventionNanjing CityJiangsu ProvinceChina department of epidemiology School of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Nanjing City Center for Disease Control and prevention Nanjing CityJiangsu ProvinceChina Chinese Antituberculosis Association BeijingChina National Institutes for Food and Drug Control BeijingChina

Introduction:Newer skin tests,including the ESAT6-CFP10(EC)skin test,were recommended for diagnosing Mycobacterium tuberculosis(***)***,no data exist assessing the diagnostic performance of the EC skin test among foreign students with different skin ***:A cohort study at Nanjing Medical University screened incoming foreign *** EC skin test was used to assess for *** infection,and results were read at 24,48,72,and 96-hours ***:Among 96 participants,*** infection rates at 24,48,72,and 96-hours post-injection were 3.13%,7.29%,13.54%,and 9.38%,*** infection rates were lower among individuals with darker skin tones,the difference was not statistically significant(P=0.186),and variations were consistent across different measurement *** analysis revealed 5.3%in the continuousincreasing group,86.5%in the low-stable group,and 5.2%in the elevated-decreasing ***,participants in the elevated-decreasing group had lighter skin tones,with trajectory patterns consistent across different skin ***:The EC skin test is safe,and redness diameter is a more reliable indicator than *** should be collected within 48 to 72 hours,with verification at 72 hours crucial if initial results are ***,skin color does not affect EC skin test outcomes.

关键词： CFP10 Skin Nanjing

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