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Device-measured physical activity and sedentary time in the Nordic countries:A scoping review of population-based studies

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Journal of Sport and Health Science 2024年第5期13卷 650-660页

作者： Ing-Mari Dohrn Jakob Tarp Jostein Steene-Johannessen Tommi Vasankari Maria Hagströmer Division of Physiotherapy Department of NeurobiologyCare Sciences and SocietyKarolinska Institutet14183 HuddingeSweden Department of Sports Medicine Norwegian School of Sports Sciences0806 OsloNorway UKK Institute for Health Promotion Research 33500 TampereFinland Faculty of Medicine and Health Technology Tampere University33100 TampereFinland Academic Primary Health Care Centre Region Stockholm13365 StockholmSweden

Purpose:The purpose of this scoping review was to summarize and describe the methodology and results from population-based studies of physical activity and sedentary time measured with devices in the Nordic countries(Denmark,Finland,Iceland,Norway,and Sweden)and published in 2000 or ***:A systematic search was carried out in PubMed and Web of Science in June 2023 using predefined search ***:Fourteen unique research projects or surveillance studies were ***,2 surveillance studies published by national agencies were included,resulting in a total of 16 studies for *** surveillance systems exist in Finland and Norway,with regular survey waves in school-aged children/adolescents and *** Denmark,recent nationally representative data have been collected in school children *** far,Sweden has no regular national surveillance system using device-based data *** studies were found from *** first study was conducted in 2001 and the most recent in 2022,with most data collected from 2016 to *** studies included children/adole scents 6-18 years,no study included *** total 11 studies included adults,of which 8 also covered older *** study focused specifically on older *** analytical sample size ranged from 205 to 27,*** methodology is presented,such as information on sampling strategy,device type and placement,wear protocols,and physical activity classification *** of physical activity and sedentary time in children/adolescents,adults,and older adults across the Nordic countries are ***:A growing implementation of device-based population surveillance of physical activity and sedentary behavior in the Nordic countries has been *** variety of devices,placement,and data procedures both within and between the Nordic countries highlights the challenges when it comes to comparing study outcomes as well as the need for more standa

关键词： Accelerometer Light intensity Moderate-vigorous intensity Surveillance Wearable devices

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MEFV,IRF8,ADA,PEPD,and NBAS gene variants and elevated serum cytokines in a patient with unilateral sporadic Meniere's disease and vascular congestion over the endolymphatic sac

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Journal of Otology 2022年第3期17卷 175-181页

作者： Jing Zou Zikai Zhao Guoping Zhang Qing Zhang Ilmari Pyykko Department of Otolaryngology-Head and Neck Surgery Changhai HospitalSecond Military Medical UniversityShanghaiChina Faculty of Information Technology and Communication Sciences Tampere UniversityTampereFinland Hearing and Balance Research Unit Field of OtolaryngologySchool of MedicineFaculty of Medicine and Health TechnologyTampere UniversityTampereFinland

The etiology and underlying mechanism of Meniere's disease(MD)development are still unknown,although inflammation and autoimmunity have been implicated as underlying *** human endolymphatic sac(ES)has been reported to have innate and adaptive immune capacity in local immune *** vivo demonstration of inflammation of the ES in patients with MD is missing in the *** report the case of a 47-year-old female patient diagnosed with unilateral MD with genetic variants and cytokine markers indicating inflammation and vascular congestion of the *** hydrops in the right cochlea(grade 2)and vestibulum(grade 3)were detected using *** carried heterozygous variants in MEFV(c.442G>C),IRF8(c.1157G>T),ADA(c.445C>T),PEPD(c.151G>A),NBAS(c.4049T>C),CSF2RB(c.2222C>T),HPS6(c.277G>T),IL2RB(c.1109C>T),IL12RB1(c.1384G>T),IL17RC(c.260_271del GCAAGAGC TGGG),LIG1(c.746G>A),RAG1(c.650C>A),and SLX4(c.1258G>C,c.5072A>G).In the serum,the levels of granulocyte colony-stimulating factor(G-CSF),macrophage inflammatory protein 1a,and IL7 were significantly elevated,and the level of IL2Ra was *** administration of dexamethasone temporarily alleviated her hearing *** vertigo was significantly relieved but remained slight after ES administration of corticosteroids.

关键词： Meniere's disease Autoinflammation Autoimmune Immune organ Endolymphatic sac

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Dexamethasone does not affect endolymphatic hydrops(EH)in patients with Meniere's disease within 24 h,and intratympanic administration of gadolinium plus dexamethasone simplifies high-quality imaging of EH using a novel protocol of 7 min

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Journal of Otology 2022年第3期17卷 164-174页

作者： Jing Zou Zikai Zhao Hongbin Li Guoping Zhang Qing Zhang Jianping Lu Ilmari Pyykko Department of Otolaryngology-Head and Neck Surgery Changhai HospitalSecond Military Medical UniversityShanghaiChina Department of Radiology Changhai HospitalSecond Military Medical UniversityShanghaiChina Faculty of Information Technology and Communication Sciences Tampere UniversityTampereFinland Hearing and Balance Research Unit Field of OtolaryngologySchool of MedicineFaculty of Medicine and Health TechnologyTampere UniversityTampereFinland

Background:Intratympanic administration of gadolinium chelate allows for a better visualization of endolymphatic hydrops(EH)using MRI than intravenous injection and was recently further improved to facilitate high-quality imaging of EH in 7 *** aim of the present study was to simplify the intratympanic administration protocol by mixing gadolinium chelate with therapeutic dexamethasone and to evaluate the effects of this mixture on the visualization of EH in *** and methods:In an in vitro study,the potential impact of gadolinium-diethylenetriamine pentaacetic acid(Gd-DTPA)on the stability of dexamethasone was evaluated by analyzing dynamic changes in dexamethasone with high-performance liquid chromatography(HPLC)after mixing with *** patients with definite Meniere's disease(MD)were recruited to study the potential interference of dexamethasone on MRI visualization of EH,and 49 patients with MD were recruited to evaluate the effect of intratympanic injection of Gd-DTPA mixed with dexamethasone on MRI of EH using a 3T MR machine and a novel heavily T2-weighted 3-dimensional fluid-attenuated inversion recovery reconstructed using a magnitude plus zero-filled interpolation(hT2FLAIR-MZFI)***:The retention times and peak area of dexamethasone in HPLC were not modified by the addition of *** grading in the cochlea and vestibule was not influenced in any ear by intratympanic injection of *** inner ear images were obtained from all patients,and EHs with various grades were *** were significant correlations between diagnosis and cochlear EH(p<0.01,Spearman's Rho),between diagnosis and vestibular EH(p<0.01,Spearman's Rho),and between cochlear and vestibular EH(p<0.01,Spearman's Rho).The distribution of Gd-DTPA plus dexamethasone negatively correlated with the grade of vestibular *** of the endolymph-perilymph barrier was detected in one cochlea and three vestibules of 59 inner ears with ***

关键词： Meniere's disease Endolymphatic hydrops MRI Contrast agent Therapeutics Topical administration

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Antibodies in celiac disease:implications beyond diagnostics

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Cellular & Molecular Immunology 2011年第2期8卷 103-109页

作者： Sergio Caja Markku Maki Katri Kaukinen Katri Lindfors Pediatric Research Centre University of Tampere and Tampere University HospitalTampereFinland medical school University of Tampere and Department of Gastroenterology and Alimentary Tract SurgeryTampere University HospitalTampereFinland

Celiac disease is a multisystemic dietary,gluten-induced autoimmune disorder characterized by the presence of transglutaminase(TG)2 serum *** autoantibodies targeting members of the TG family(TG2,TG3 and TG6)are found deposited in small-bowel mucosa and in extraintestinal tissues affected by the *** autoantibodies against other self-antigens also emerge in untreated celiac disease *** villous atrophy and crypt hyperplasia in small-bowel biopsy samples are still the gold standards in diagnostics,celiac disease-specific antibodies are widely used as diagnostic ***-induced small-bowel mucosal T-cell response is the cornerstone in the pathogenesis of the disorder,but humoral immunity may also play a central *** review article is focused on the autoantibodies that occur in the context of celiac *** article summarizes the diagnostic utility of different celiac-related antibodies and discusses their roles in the pathogenesis of the disease.

关键词： antibody celiacdisease diagnostics pathogenesis

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Prevalence of lactase persistent/non-persistent genotypes and milk consumption in a young population in north-west Russia

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World Journal of Gastroenterology 2009年第15期15卷 1849-1853页

作者： Yulia Khabarova Suvi Torniainen Hanna Nurmi Irma Jrvel Mauri Isokoski Kari Mattila Department of Family Medicine Northern State Medical University Department of medical Genetics University of Helsinki tampere school of Public Health University of Tampere medical school University of Tampere33014 and Centre of General PracticeHealth District of Pirkanmaa

AIM:To estimate the prevalence of the lactase non-persistent genotype(C/C-13910)in a northern Russian population in accordance with ethnicity,and to evaluate self-reported milk consumption depending on lactase activity. METHODS:Blood samples for genotyping lactase activity,defining the C/T-13910 variant by polymerase chain reaction,and direct sequencing were taken from 231 medical students of Russian origin aged 17-26 years. We analyzed milk product consumption by questionnaire which was specially designed for the estimation of milk consumption and abdominal complaints. RESULTS:We found that the prevalence of the C/C-13190 genotype in the northern Russian population was 35.6%.The other genotypes nearby C/T-13910 and associated with lactase activity were not present in the study *** consumption of milk among people with the non-persistent genotype tended to be lower than among the lactose tolerant subjects,but was not statistically ***:An investigation of the lactase persistent genotype in a northern Russian population has not been performed *** genotype did not affect the consumption of milk products in this population which could be explained by low consumption of milk products among the entire study population.

关键词：消费人群牛奶产品乳糖酶基因型俄罗斯持久性人口西北

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Endomysial antibodies predict celiac disease irrespective of the titers or clinical presentation

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World Journal of Gastroenterology 2012年第20期18卷 2511-2516页

作者： Kalle Kurppa Tiia Rsnen Pekka Collin Sari Iltanen Heini Huhtala Merja Ashorn Pivi Saavalainen Katri Haimila Jukka Partanen Markku Mki Katri Kaukinen Pediatric Research Centre University of Tampere and Tampere University HospitalFin-33014Tampere Finland Department of Gastroenterology and Alimentary Tract Surgery Tampere University Hospital and School of MedicineUniversity of TampereFin-33014 TampereFinland tampere school of Public Health University of TampereFin-33014TampereFinland Department of medical Genetics and Research Program for Molecular Medicine University of Helsinki Fin-00014HelsinkiFinland Research and Development Finnish Red Cross Blood ServiceFin-00310HelsinkiFinland

AIM:To investigate the association between serum antibody levels and a subsequent celiac disease diag-nosis in a large series of children and adults. METHODS:Besides subjects with classical gastrointestinal presentation of celiac disease,the study cohort included a substantial number of individuals with extraintestinal symptoms and those found by screening in at-risk *** 405 patients underwent clinical,serological and histological *** collection of data,the antibody values were further graded as low[endomysial(EmA)1:5-200,transglutaminase 2 antibodies(TG2-ab)5.0-30.0 U/L]and high (EmA 1:≥500,TG2-ab≥30.0 U/L),and the serological results were compared with the small intestinal mucosal histology and clinical presentation. RESULTS:In total,79%of the subjects with low and 94%of those with high serum EmA titers showed small-bowel mucosal villous ***, 96%of the 47 EmA positive subjects who had normal mucosal villi and remained on follow-up either subsequently developed mucosal atrophy while on a glutencontaining diet,or responded positively to a glutenfree diet. CONCLUSION:Irrespective of the initial serum titers or clinical presentation,EmA positivity as such is a very strong predictor of a subsequent celiac disease diagnosis.

关键词：疾病诊断临床表现抗体水平腹腔滴度预测内膜转谷氨酰胺酶

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Peptic ulcer and childhood adversities experienced by working-aged people

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World Journal of Gastroenterology 2009年第27期15卷 3405-3410页

作者： Markku PT Sumanen Markku J Koskenvuo Lauri H Sillanmki Kari J Mattila Kangasala Health Center and Medical School University of TampereFI 33014 Finland Department of Public Health University of HelsinkiFI 00014 Finland Department of General Practice University of Tampere Medical School and Hospital District of PirkanmaaFI 33014 Finland

AIM: To study the association between self-reported peptic ulcer and childhood ***: The Health and Social Support Study (HeS-Sup) population consisted of a stratif ied random sample drawn from the Finnish Population Register in four age groups: 20-24, 30-34, 40-44 and 50-54. The survey was carried out by postal questionnaire during 1998, with a response rate of 40.0%. A follow-up questionnaire was sent during 2003 to all those who responded to the f irst. Altogether 19 626 individuals returned the follow-up questionnaire; a response rate of 75.8%. The subjects were asked whether a doctor had told them that they have or have had peptic ulcer. The analyses covered those who responded aff irmatively to both the baseline and the follow-up enquiries (n = 718). Those not re-porting a peptic ulcer in either of the two questionnaires (n = 17 677) were taken as controls. The subjects were further requested (through six questions) to think about their childhood ***: The most common adversities mentioned were long-lasting financial difficulties in the family, serious conflicts in the family, and a family member seriously or chronically ill. All the adversities reported, except parental divorce, were more common among peptic ulcer patients than among controls (P values varied between < 0.001 and 0.003). Age- and sex-adjusted odds ratios (OR) of childhood adversities in the multivariate logistic analysis for self-reported pep-tic ulcer varied between 1.45 and 2.01. Adjusting for smoking, heavy drinking, stress and nonsteroidal anti-inflammatory drug use had no further influence (ORs between 1.22 and 1.73).CONCLUSION: Our findings suggest that childhood adversities maintain a connection with and have a predictive role in the development of peptic ulcer.

关键词：消化性溃疡工作经验老年人逆境童年

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China-Europe Higher Education Cooperation: Opportunities and Challenges

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Frontiers of Education in China 2019年第2期14卷 167-179页

作者： Yuzhuo CAI school of Management University of TampereTampere 33014Finland

This article introduces Frontiers of Education in China’s special issue on China-Europe higher education *** is more than simply an introduction to the five studies collected for the special ***,it provides an overview of higher education cooperation between China and Europe from the perspective of opportunities and *** background information will help readers not only better understand the studies included in the special issue,but also link these studies to a bigger picture of China-Europe higher education cooperation.

关键词： higher education cooperation internationalization of higher edu-cation China Europe China-EU relations

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Characterizing and Understanding Development of Social Computing Through DBLP: A Data-Driven Analysis

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Journal of Social Computing 2022年第4期3卷 287-302页

作者： Jiaqi Wu Bodian Ye Qingyuan Gong Atte Oksanen Cong Li Jingjing Qu Felicia F.Tian Xiang Li Yang Chen the Shanghai Key Lab of Intelligent Information Processing the School of Computer ScienceFudan UniversityShanghai 200438China the Faculty of Social Sciences Tampere UniversityTampere 33100Finland school of Information Science and Technology Fudan UniversityShanghai 200438China Shanghai Artificial Intelligence Laboratory Shanghai 200232China. school of Social Development and Public Policy Fudan UniversityShanghai 200433China. Institute of Complex Networks and Intelligent Systems Shanghai Research Institute for Intelligent Autonomous SystemsTongji UniversityShanghai 200092China.

During the past decades,the term“social computing”has become a promising interdisciplinary area in the intersection of computer science and social *** this work,we conduct a data-driven study to understand the development of social computing using the data collected from Digital Bibliography and Library Project(DBLP),a representative computer science bibliography *** have observed a series of trends in the development of social computing,including the evolution of the number of publications,popular keywords,top venues,international collaborations,and research *** findings will be helpful for researchers and practitioners working in relevant fields.

关键词： social computing Digital Bibliography and Library Project(DBLP) bibliometric evolution visualization

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A Configuration Deactivation Algorithm for Boosting Probabilistic Roadmap Planning of Robots

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International Journal of Automation and computing 2012年第2期9卷 155-164页

作者： Mika T. Rantanen Martti Juhola Computer Sciences School of Information Sciences University of Tampere

We present a method to improve the execution time used to build the roadmap in probabilistic roadmap planners. Our method intelligently deactivates some of the configurations during the learning phase and allows the planner to concentrate on those configurations that axe most likely going to be useful when building the roadmap. The method can be used with many of the existing sampling algorithms. We ran tests with four simulated robot problems typical in robotics literature. The sampling methods applied were purely random, using Halton numbers, Gaussian distribution, and bridge test technique. In our tests, the deactivation method clearly improved the execution times. Compared with pure random selections, the deactivation method also significantly decreased the size of the roadmap, which is a useful property to simplify roadmap planning tasks.

关键词： Probabilistic roadmaps motion planning collision avoidance sampling algorithms robotics.

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